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31. 发明公开

EP2775902A4 INFLATABLE CUFF WITH BUILT-IN DRUG DELIVERY DEVICE FOR DYNAMIC DRUG THERAPY RESPONSE TO BLOOD PRESSURE INCIDENTS 失效转让
标题翻译：借助内置的药物供应系统充气管套一个动态的治疗药物响应血压征候
公开(公告)号：EP2775902A4
公开(公告)日：2015-05-06
申请号：EP12847228
申请日：2012-11-08
申请人： ELWHA LLC
发明人： BAYM MICHAEL H , BOYDEN EDWARD S , HYDE RODERICK A , KARE JORDIN T , LEUTHARDT ERIC C , MYHRVOLD NATHAN P , WOOD JR LOWELL L
IPC分类号： A61B5/00 , A61B5/02 , A61B5/022 , A61B5/026 , A61B8/04 , A61B8/06 , A61K9/00 , A61M5/142 , A61M5/172 , A61M5/30 , A61M37/00 , A61N1/04 , A61N1/30 , A61N1/32
CPC分类号： A61B8/04 , A61B5/02007 , A61B5/022 , A61B5/026 , A61B5/4839 , A61B5/6833 , A61B8/06 , A61K9/0009 , A61K9/0021 , A61M5/14248 , A61M5/14276 , A61M5/1723 , A61M5/30 , A61M37/00 , A61M37/0015 , A61M37/0092 , A61M2037/0007 , A61M2230/30 , A61N1/0412 , A61N1/0428 , A61N1/0492 , A61N1/30 , A61N1/325
摘要： A dermal or transdermal drug-delivery skin patch has a blood pressure sensor structurally integrated or built into it. The skin patch when attached to a skin portion of an individual determines a blood pressure of the individual and in response needle-lessly delivers a treatment drug to the individual if necessary.
摘要翻译：甲真皮或经皮药物递送皮肤贴片具有结构上集成或内置到它血压传感器。皮肤贴剂当连接到个体的皮肤部分bestimmt个体的血压，并响应针lessly递送治疗药物的个体，如果是必要的。

32. 发明授权

EP2203113B1 DIAGNOSTISCHE SENSOREINHEIT 有权
标题翻译：诊断传感器单元
公开(公告)号：EP2203113B1
公开(公告)日：2015-02-25
申请号：EP08801909.6
申请日：2008-09-08
申请人： Flore, Ingo
发明人： CHO, Ok Kyung , KIM, Yoon Ok
IPC分类号： A61B5/00 , A61B5/01 , A61B5/02 , A61B5/022 , A61B5/024 , A61B5/0402 , A61B5/053 , A61B5/1455
CPC分类号： A61B5/00 , A61B5/01 , A61B5/02 , A61B5/022 , A61B5/02416 , A61B5/02438 , A61B5/0402 , A61B5/0404 , A61B5/0537 , A61B5/14532 , A61B5/1455 , A61B5/6887

33. 发明授权

EP2680745B1 A METHOD AND DEVICE FOR POSITIONING A DOPPLER ULTRASOUND TRANSDUCER FOR BLOOD FLOW MEASUREMENT AND A SYSTEM FOR BLOOD FLOW MEASUREMENT 有权
标题翻译：方法和装置的多普勒超声波换能器的用于血流测量血流测量和定位系统的
公开(公告)号：EP2680745B1
公开(公告)日：2015-01-14
申请号：EP12712359.4
申请日：2012-02-27
申请人： Koninklijke Philips N.V.
发明人： YAN, Ming , CHEN, Yinan
IPC分类号： A61B8/00 , A61B5/022 , A61B8/06 , A61B8/08
CPC分类号： A61B8/06 , A61B5/022 , A61B8/08 , A61B8/0891 , A61B8/42 , A61B8/488
摘要： The method of positioning a Doppler ultrasound transducer for performing blood flow measurement according to the invention comprises the steps of: detecting a pressure oscillation signal from an inflated cuff placed on patient's artery; detecting an ultrasound pulse signal from the Doppler ultrasound transducer placed along the artery; deriving a first signal from the pressure oscillation signal and the ultrasound pulse signal, the first signal indicating the degree of synchronization between the pressure oscillation signal and the ultrasound pulse signal; and outputting an indication signal to indicate the Doppler ultrasound transducer is in a desired position when the first signal satisfies a predefined condition. Since the synchronization property of the cuff pressure oscillation signal and the ultrasound signal caused by the blood flow is utilized to determine whether the transducer is well positioned or not, ultrasound signal, which is a pulse signal but not reflecting the blood flow of the artery, could be determined as not in synchronization with the oscillation signal and therefore the accuracy of the positioning could be improved.

35. 发明公开

EP2736418A1 METHOD AND DEVICE FOR DETECTING OCCLUSION/REOPENING OF AN ARTERY AND SYSTEM FOR MEASURING SYSTOLIC BLOOD PRESSURE 审中-公开
标题翻译：用于测量收缩压的方法和装置检测堵塞/重开动脉与系统的
公开(公告)号：EP2736418A1
公开(公告)日：2014-06-04
申请号：EP12770221.5
申请日：2012-07-17
申请人： Koninklijke Philips N.V.
发明人： CHEN, Yinan , LU, Weijia , ZHONG, Jianyi , ANAND, Ajay , PETRUZZELLO, John
IPC分类号： A61B8/06 , A61B8/04 , A61B5/022
CPC分类号： A61B8/5223 , A61B5/022 , A61B5/6824 , A61B8/04 , A61B8/06 , A61B8/4483 , A61B8/488
摘要： This invention provides a method and a device for detecting occlusion and/or reopening of an artery of a body caused by a changing pressure applied on the artery as well as a system for measuring the systolic blood pressure of an artery of a body. The method comprises the steps of: obtaining a blood flow signal indicative of a change of the blood flow in the artery caused by the changing pressure, using a Doppler Ultrasound transducer attached to the exterior of the body; deriving, from the blood flow signal, at least one variable of a first variable indicative of the magnitude of the blood flow and a second variable indicative of the periodicity of the blood flow; and detecting the occlusion and/or reopening of the artery on the basis of the at least one variable. In this way, the occlusion/reopening of the artery can be detected automatically. Since the need to manually detect the occlusion and reopening of the artery by listening with a stethoscope or a Doppler probe is eliminated, the detecting result is more predictable and repeatable, and therefore also more accurate.

36. 发明公开

EP2732759A1 System and method of measurement of systolic blood pressure 审中-公开
标题翻译：系统和Verfahren zur Messung von systolischem Blutdruck
公开(公告)号：EP2732759A1
公开(公告)日：2014-05-21
申请号：EP13192338.5
申请日：2013-11-11
申请人： Jerusalem College of Technology
发明人： Nitzan, Meir
IPC分类号： A61B5/021 , A61B5/022 , A61B5/00 , A61B5/026 , A61B5/024
CPC分类号： A61B5/02255 , A61B5/02108 , A61B5/022 , A61B5/02208 , A61B5/02416 , A61B5/0261 , A61B5/6801 , A61B5/7203 , A61B5/7235 , A61B5/725
摘要： Systolic blood pressure of a subject is determined by application of monotonic changing pressure conditions over a region of an organ of the subject, simultaneous illumination of a tissue in the pressurized organ with light and measurement of optical data indicative of passage of the light through the tissue and of pressure data indicative of the pressure being applied over said region of said organ. At least one pulsatile and at least one baseline component are determined from the measured optical data and changes are then identified in each of the components, said changes indicative that the pressure applied over the organ is smaller than a systolic blood pressure of the subject. The systolic blood pressure of the subject may be determined as a maximal applied pressure at which at least one of the changes in the pulsatile component and the changes in the baseline component started to appear.
摘要翻译：受试者的收缩压通过在受试者的器官的区域上施加单调变化的压力条件来确定，同时用光照射加压器官中的组织，并且测量指示光通过组织的光学数据以及指示施加在所述器官的所述区域上的压力的压力数据。从测量的光学数据确定至少一个脉冲和至少一个基线分量，然后在每个组分中鉴定变化，所述改变指示施加在器官上的压力小于受试者的收缩压。受试者的收缩压可以确定为最大施加压力，在该最大施加压力下，脉搏成分中的至少一个变化和基线组分的变化开始出现。

37. 发明公开

EP2727524A1 Method and apparatus for measuring blood volume 有权
标题翻译： Verfahren und Vorrichtung zum Messen der Blutmenge
公开(公告)号：EP2727524A1
公开(公告)日：2014-05-07
申请号：EP13189096.4
申请日：2013-10-17
申请人： Nihon Kohden Corporation
发明人： Sugo, Yoshihiro , Sakai, Tomoyuki , Terao, Mami
IPC分类号： A61B5/029 , A61B5/08 , A61B5/021 , A61B5/022 , A61B5/0215
CPC分类号： A61B5/029 , A61B5/0205 , A61B5/02108 , A61B5/02125 , A61B5/0215 , A61B5/022 , A61B5/0816
摘要： Method for measuring a blood volume is provided. At least two types of respiratory variation data; for instance, data pertinent to respiratory variations in stroke volume (SVV) data, data pertinent to respiratory variations in an amplitude of a pulse wave (PAV), a pulse wave transit time (PWTT) in a respiratory cycle, and a heart rate (HR) in a predetermined time, are measured, and patient's inherent coefficients α, β, and K are calculated, whereby a cardiac output can be determined by an equation CO = K (α * PWTT + β) * HR.
摘要翻译：提供了测量血容量的方法。至少两种呼吸变异数据; 例如，与呼吸量变化（SVV）数据有关的数据，与脉搏波（PAV）的振幅中的呼吸变化相关的数据，呼吸周期中的脉搏波过渡时间（PWTT）和心率（ HR），并且计算患者的固有系数±，²和K，由此可以通过方程式CO = K（±* PWTT +²）* HR确定心输出量。

38. 发明授权

EP1679031B1 ELECTRONIC BLOOD PRESSURE METER 有权
标题翻译：电子血压计
公开(公告)号：EP1679031B1
公开(公告)日：2014-03-26
申请号：EP04770993.6
申请日：2004-07-28
申请人： A & D Company, Ltd.
发明人： OZAKI, Shinobu, c/o A & D Company Ltd. , TODA, Shigenobu, c/o A & D Company Ltd. , AIBA, Toshiharu, c/o A & D Company Ltd.
IPC分类号： A61B5/022
CPC分类号： A61B5/7475 , A61B5/022

39. 发明授权

EP2436308B1 Monitoring compliance using venous refill detection 有权转让
标题翻译：使用Venenauffüllerkennung合规性监控
公开(公告)号：EP2436308B1
公开(公告)日：2013-12-11
申请号：EP11182113.8
申请日：2011-09-21
申请人： Covidien LP
发明人： Watson, Kristin , Vess, Mark A
IPC分类号： A61B5/026 , A61H23/04
CPC分类号： A61B5/4833 , A61B5/022 , A61B5/026 , A61B5/6802 , A61B5/6828 , A61B5/7275 , A61H9/0078 , A61H2201/0184 , A61H2201/164 , A61H2201/5007 , A61H2201/5069 , A61H2201/5071 , A61H2205/10 , A61H2209/00 , G06F19/00
摘要： Monitoring patient compliance with a compression therapy regimen. Venous Refill Time (VRT) is monitored via a pressure sensor in a bladder of a compression system. A controller of the compression system correlates the monitored VRT to a predetermined threshold to determine whether the patient is using the compression system.

40. 发明公开

EP2665043A1 Method and system for providing information from a patient-specific model of blood flow 审中-公开
标题翻译：方法和系统提供特定于患者的血流模型的信息
公开(公告)号：EP2665043A1
公开(公告)日：2013-11-20
申请号：EP12171882.9
申请日：2012-06-13
申请人： Heartflow, Inc.
发明人： Hart, Gregory Richard , Stevens, John Henry
IPC分类号： G06T19/20 , G06F3/048
CPC分类号： G06F19/3437 , A61B5/02007 , A61B5/021 , A61B5/022 , A61B5/026 , A61B5/0263 , A61B5/055 , A61B5/7275 , A61B5/7278 , A61B5/7425 , A61B5/7445 , A61B5/748 , A61B6/03 , A61B6/032 , A61B6/466 , A61B6/504 , A61B6/5217 , A61B8/06 , A61B34/10 , A61B2034/104 , A61B2576/023 , G06F3/017 , G06F3/04815 , G06F3/0486 , G06F3/0488 , G06F17/5009 , G06F19/00 , G06F19/12 , G06F19/321 , G06T15/00 , G06T17/00 , G06T19/20 , G06T2200/04 , G06T2200/24 , G06T2210/41 , G06T2219/2016 , G16H50/50
摘要： Embodiments include a system for providing blood flow information for a patient. The system may include at least one computer system including a touchscreen. The at least one computer system may be configured to display, on the touchscreen, a three-dimensional model representing at least a portion of an anatomical structure of the patient based on patient-specific data. The at least one computer system may also be configured to receive a first input relating to a first location on the touchscreen indicated by at least one pointing object controlled by a user, and the first location on the touchscreen may indicate a first location on the displayed three-dimensional model. The at least one computer system may be further configured to display first information on the touchscreen, and the first information may indicate a blood flow characteristic at the first location.
摘要翻译：实施例包括用于为患者提供血流信息的系统。该系统可以包括至少一个计算机系统，其包括触摸屏。所述至少一个计算机系统可被配置成显示在触摸屏上，表示至少基于患者特异性数据的患者的解剖结构的一部分的三维模型。因此，该至少一个计算机系统可被配置为接收第一输入与由用户控制的至少一个指向对象指示的触摸屏上的第一位置，和在触摸屏上的第一位置可指示在所显示的第一位置三维模型。所述至少一个计算机系统可被进一步配置为显示在触摸屏上的第一信息，并且第一信息可以指示在第一位置处的血流特性。

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