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21. 发明授权

EP2498835B1 BIODEGRADABLE THERMOPLASTIC ELASTOMERS 有权
标题翻译：生物学ABBAUBARE热塑性弹性体
公开(公告)号：EP2498835B1
公开(公告)日：2017-05-24
申请号：EP10830295.1
申请日：2010-11-15
申请人： Nanyang Technological University
发明人： VENKATRAMAN, Subramanian , ABADIE, Marc , WIDJAJA, Leonardus, Kresna , LIPIK, Vitali
IPC分类号： A61L31/06 , A61L17/00 , A61L27/18 , A61L29/06 , C08G63/91 , C08G64/18 , C08G83/00
CPC分类号： C08G63/06 , A61L17/06 , A61L17/12 , A61L27/18 , A61L27/58 , C08G63/81 , C08G63/912 , C08G64/18 , C08G2261/126 , C08L67/04

22. 发明公开

EP2962702A1 SUTURE TO BE USED IN PRODUCING MEDICAL INSTRUMENT PROVIDED WITH SUTURED PART, METHOD FOR USING SAME AND MEDICAL INSTRUMENT SEWN USING SAME 审中-公开
标题翻译：煤层生产与缝制部的医疗器械，并使用方法缝纫医疗器械
公开(公告)号：EP2962702A1
公开(公告)日：2016-01-06
申请号：EP13876205.9
申请日：2013-02-26
申请人： NICEM LTD
发明人： NOISHIKI, Yasuharu
IPC分类号： A61L17/00 , A61F2/06 , A61F2/24 , A61L27/00 , A61L31/00
CPC分类号： A61F2/07 , A61B17/06166 , A61F2/24 , A61F2002/065 , A61F2002/075 , A61F2002/826 , A61L17/00 , Y10T156/10
摘要： A suture to be used in producing a medical instrument provided with a sutured site such as a stent graft, an artificial blood vessel or an artificial heart valve, namely, a suture for sewing a medical instrument. The suture comprises two components, i.e., a high melting-point component and a low-melting point component, the difference between the melting points of components being 30°Cor more and the low-melting point component is exposed on the suture surface entirely along the length direction. The suture is, for example, a multifilament yarn comprising a combination of a high melting-point filament (3) with a low-melting point filament (4) shown in Fig.2 or a composite filament comprising the high melting-point component and the low-melting point component, or a yarn wherein the high melting-point component is coated with the low-melting point component. When a medical material formed of a fabric or a film is sutured or knotted with the suture and then the suture site is heated at such a temperature allowing not the high-melting point component but the low-melting point component alone to melt, the sutured site is fused and fixed. Thus, a knot or a seam, which sustains the fiber shape and strength and never becomes loose, can be formed.
摘要翻译：在制造设置有缝合部位的医疗器械中使用的缝合线：如支架移植物，人工血管或人造心脏瓣膜，即，用于缝合的医疗器械的缝合线。所述缝合线包括两个组件，即，高熔点组分和低熔点组分，成分为30°肺心病更多的熔点和低熔点组分之间的差被缝合线表面上完全沿露出长度方向。缝合线是，对于实施例中，复丝纱，其包括高熔点灯丝（3）与低熔点长丝的组合在图2中（4）所示或复合长丝包含所述高熔点组分和的低熔点组分，或worin所述高熔点组分的纱线涂有低熔点组分。当制成的织物或薄膜的医用材料被缝合或用缝合线打结，然后将缝合部位被加热在寻求的温度允许不是高熔点组分，但单独的低熔点组分熔化，所述缝合网站融合和固定。因此，一个结或一个接缝，其中维持所述纤维的形状和强度，永不变松，可以形成。

23. 发明授权

EP2279013B1 SHAPE-MEMORY SELF-RETAINING SUTURES, METHODS OF MANUFACTURE, AND METHODS OF USE 有权
标题翻译：自停止END形状记忆缝，处理和使用方法
公开(公告)号：EP2279013B1
公开(公告)日：2015-08-05
申请号：EP09735127.4
申请日：2009-04-24
申请人： Ethicon LLC
发明人： GORALTCHOUK, Alexei , LAI, John , HERRMANN, Robert, A
IPC分类号： A61L17/10 , A61B17/064 , A61L17/00 , D06M11/83 , D06M15/00 , D01F6/00 , A61B17/00 , A61B17/06
CPC分类号： A61B17/06166 , A61B2017/00526 , A61B2017/00792 , A61B2017/00867 , A61B2017/06057 , A61B2017/06176 , A61L17/00 , A61L2400/16 , D01F6/00 , D06M11/83 , D06M15/00

24. 发明公开

EP2832380A1 BIODEGRADABLE MATERIAL AND METHOD FOR PRODUCING BIODEGRADABLE MATERIAL 有权
标题翻译：生物材料ABBAUBARES材料VERFAHREN ZUR HERSTELLUNG VON生物学ABBAUBAREM材料
公开(公告)号：EP2832380A1
公开(公告)日：2015-02-04
申请号：EP13768529.3
申请日：2013-03-28
申请人： Toray Industries, Inc.
发明人： FUJITA, Masaki , NAKANISHI, Megumi , TANAHASHI, Kazuhiro
IPC分类号： A61L31/00 , A61L15/64 , A61L17/00 , C08G63/06 , C08L101/16
CPC分类号： A61L15/26 , A61L15/64 , A61L24/0042 , A61L24/046 , A61L31/148 , A61L2430/36 , C08G63/08 , C08G63/668 , C08L67/02 , C08L67/025 , C08L67/04 , C08L101/16
摘要： The present invention aims to provide a biodegradable material having an enhanced shape recovery rate after deformation of the material and an improved flexibility. The present invention provides a biodegradable material which is a chemically cross-linked product between a multivalent compound A having 3 or more functional groups X such as hydroxyl group; and a multivalent compound B having 3 or more functional groups Y such as carboxyl group wherein chemical cross-linkage(s) is/are formed by condensation reaction of the functional group(s) X and the functional group(s) Y; wherein the value of (y + z)/(x + z) is 1.2 to 4.0 when MA ≥ MB, and the value of (x + z)/(y + z) is 1.2 to 4.0 when MA
摘要翻译：本发明的目的在于提供一种生物降解材料，其具有在材料变形后具有增强的形状恢复率和改进的柔性。本发明提供一种生物降解性材料，其是具有3个以上官能团X的多价化合物A（如羟基）上的化学交联产物; 和具有3个以上官能团Y的多价化合物B，例如羧基，其中通过官能团X和官能团Y的缩合反应形成化学交联; 其中当MA≤MB时，（y + z）/（x + z）的值为1.2〜4.0，当MA

25. 发明授权

EP1804843B1 ADHESIVE SUTURE STRUCTURE 有权
标题翻译：胶粘式接缝结构
公开(公告)号：EP1804843B1
公开(公告)日：2014-12-03
申请号：EP05804217.7
申请日：2005-10-14
申请人： Covidien LP
发明人： VIOLA, Frank, J.
IPC分类号： A61B17/06 , A61L17/00
CPC分类号： A61B17/1114 , A61B17/00491 , A61B17/06 , A61B17/072 , A61B17/11 , A61B17/115 , A61B17/1155 , A61B2017/00893 , A61B2017/06185 , A61B2017/07214 , A61B2090/037 , A61L17/005 , A61L2300/406 , A61L2300/414

26. 发明公开

EP2374416A3 Deployment system for surgical suture 审中-公开
标题翻译：应用系统的手术缝合线
公开(公告)号：EP2374416A3
公开(公告)日：2014-10-15
申请号：EP11250290.1
申请日：2011-03-11
申请人： Covidien LP
发明人： Bogart, Michael , Krehel, Gregg , Fishbein, Christopher , Pribanic, Russell , Kirsch, David , Horton, Kenneth W., Jr. , Kosa, Timothy D. , Maiorino, Nicholas , Buchter, Mark S. , Hadba, Ahmad Robert , Hodgkinson, Gerald , Bowns, William R.
IPC分类号： A61B17/04 , A61B17/062 , A61B17/00 , A61B17/06 , A61B17/29 , A61L17/00
CPC分类号： A61B17/0469 , A61B17/0491 , A61B17/06004 , A61B17/0625 , A61B2017/00004 , A61B2017/003 , A61B2017/00867 , A61B2017/00871 , A61B2017/06047 , A61B2017/0609 , A61B2017/06176 , A61B2017/2908 , A61B2017/2936 , A61L17/005 , A61L17/04 , A61L17/06 , A61L17/12 , A61L2300/00 , A61L2400/16
摘要： A suture deployment system is disclosed including a surgical needle having a flexible suture fixedly attached thereto and a target suture releasably secured to the flexible suture. Either the flexible suture or the target suture may be made of a shape memory polymer. A collar is positioned between the flexible suture and the target suture and is fixedly secured to the flexible suture. The target suture is releasably secured to the collar is such that the target suture may detach from the collar once a surgical procedure has been completed. The surgical needle is a double pointed surgical needle specifically configured to be manipulated by a surgical suturing apparatus.

27. 发明公开

EP2486946A4 BIORESORBABLE SUTURE THREAD 有权
标题翻译：可生物降解的缝纫线
公开(公告)号：EP2486946A4
公开(公告)日：2014-05-14
申请号：EP10822132
申请日：2010-10-08
申请人： OMIKENSHI KK , TOTAI CO LTD
发明人： YOSHIKAWA MASATOSHI , KAJITA HIDEKI , NOGUCHI TAKESHI , KASAI JUICHI
IPC分类号： A61L17/00
CPC分类号： A61L17/08 , A61L17/10 , C08L5/08
摘要： A bioabsorbable suture according to the present invention is characterized in that the suture is manufactured from monofilaments or multifilaments spun from a spinning raw solution containing one or two or more component(s) selected from the group consisting of chitin, chitosan, and derivatives thereof and a degrading enzyme for the component(s), and the degrading enzyme exists on a surface of the suture and in the suture.

28. 发明公开

EP2540323A3 Novel drug eluting medical devices 审中-公开
标题翻译： Neuartige arzneimitteleluierende medizinische Vorrichtungen
公开(公告)号：EP2540323A3
公开(公告)日：2014-01-08
申请号：EP12173984.1
申请日：2012-06-28
申请人： Covidien LP
发明人： Desai, Arpan
IPC分类号： A61L17/00 , A61L17/14 , A61L31/10 , A61L31/16
CPC分类号： A61L17/145 , A61L17/005 , A61L31/10 , A61L31/16 , A61L2300/258 , A61L2420/08
摘要： Medical devices possessing coatings are provided. The coatings include at least one polyelectrolyte, capable of changing the surface charge of the device to which they are applied. The polyelectrolytes permit attachment of charged bioactive agents thereto. Multiple polyelectrolytes, possessing opposite charges, may be sequentially applied to produce a medical device having multiple layers. Methods for forming such devices are also provided.
摘要翻译：提供了具有涂层的医疗设备。涂层包括至少一种聚电解质，能够改变其所施加的装置的表面电荷。聚电解质允许带电的生物活性剂附着于其上。可以依次施加具有相反电荷的多个聚电解质以制造具有多层的医疗装置。还提供了形成这种装置的方法。

29. 发明公开

EP2313122A4 DRUG DELIVERY MEDICAL DEVICE 有权转让
标题翻译：医疗解除单元
公开(公告)号：EP2313122A4
公开(公告)日：2013-10-30
申请号：EP09798764
申请日：2009-07-16
申请人： MICELL TECHNOLOGIES INC
发明人： MCCLAIN JAMES B , TAYLOR DOUGLAS , NEET JOHN
IPC分类号： A61L33/00 , A61L17/00 , A61L17/14 , A61L27/34 , A61L27/50 , A61L27/54 , A61L29/08 , A61L29/14 , A61L29/16 , A61L31/10 , A61L31/14 , A61L31/16
CPC分类号： A61L29/16 , A61F2002/30535 , A61F2250/0058 , A61K9/0024 , A61K9/0034 , A61K31/20 , A61K31/7088 , A61K31/7105 , A61K31/715 , A61K38/00 , A61L17/005 , A61L17/145 , A61L27/34 , A61L27/50 , A61L27/54 , A61L29/08 , A61L29/085 , A61L29/14 , A61L29/148 , A61L31/08 , A61L31/10 , A61L31/14 , A61L31/16 , A61L2300/406 , A61L2300/416 , A61L2300/426 , A61L2300/602 , A61L2300/608 , A61L2300/63 , A61L2420/08 , A61M2025/105
摘要： Provided is a coated implantable medical device, comprising: a substrate; and a coating disposed on said substrate, wherein said coating comprises at least one polymer and at least one pharmaceutical agent in a therapeutically desirable morphology and/or at least one active biological agent and optionally, one or more pharmaceutical carrying agents; wherein substantially all of pharmaceutical agent and/or active biological agent remains within said coating and on said substrate until the implantable device is deployed at an intervention site inside the body of a subject and wherein upon deployment of said medical device in the body of said subject a portion of said pharmaceutical agent and/or active biological agent is delivered at said intervention site along with at least a portion of said polymer and/or a at least a portion of said pharmaceutical carrying agents.

30. 发明公开

EP1916949A4 ABSORBABLE SURGICAL MATERIALS 审中-公开
标题翻译：可吸收外科手术材料
公开(公告)号：EP1916949A4
公开(公告)日：2013-03-27
申请号：EP06813822
申请日：2006-08-25
申请人： COVIDIEN LP
发明人： HADBA AHMAD R
IPC分类号： A61B17/04 , A61B17/06 , A61L17/00 , A61L17/06
CPC分类号： A61B17/06166 , A61B2017/00004 , A61B2017/00831 , A61B2017/06028 , A61B2017/06052 , A61L17/06 , A61L31/022 , A61L31/148

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