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    • 22. 发明公开
    • POWDER COMPARTMENT FOR HIGH DOSAGE DRUG DELIVERY
    • PULVERKAMMERFÜRHOCHDOSIERTE WIRKSTOFFFREISETZUNG
    • EP3099364A1
    • 2016-12-07
    • EP16722343.7
    • 2016-04-28
    • Hovione Technology Limited
    • VENTURA, JoaoVILLAX, PeterFARIA, Cristina
    • A61M15/00
    • A61M15/002A61K9/0075A61M15/0021A61M15/0028A61M15/0043A61M15/0086A61M2202/064
    • A dry powder inhaler for pulmonary or nasal use, comprising at least an inhaler body 801 and a cartridge 803 with at least one powder compartment 805 including one dose of a drug. The body has an opening 804 shaped for receiving the cartridge 803 and the means to allow a controlled sliding movement of the cartridge 803 relative to the body 801 after mounting. The cartridge powder compartment 805 comprises at least two inlets or slits 806, 809, at least one of which is a side inlet 809, for the admission of air, and a compartment outlet 807 to allow filling and fluid communication with an inhalation channel 808 provided in the body 801. In use, the patient slides the cartridge 803 relative to the body 801 from the storage position, where the inlets in the cartridge powder compartment 805 are blocked and sealed by walls comprised in the body 801, into the inhalation position, where the compartment inlets become available for the admission of air used in the dispersion of the particles there contained and the compartment outlet 807 becomes aligned with the inhalation channel 808 in the body 801 to allow the entrainment of the dose dispersed through the device and into the desired site of action during inhalation. The addition of one or more lateral vents 809 in the cartridge powder compartments induces a turbulent and swirling flow pattern that promotes improved dispersion and entrainment. The invention affords a very economical and simple device for the delivery of high dosages of inhaled medicines.
    • 一种用于肺或鼻用的干粉吸入器,至少包括吸入器主体(801)和具有至少一个包含一剂药物的粉末隔室(805)的药筒(803)。 主体具有形状用于接收盒(803)的开口(804)和用于在安装之后允许盒(803)相对于主体(801)受到控制的滑动运动的装置。 墨粉盒隔室(805)包括至少两个入口或狭缝(806,809),其至少一个是用于容纳空气的侧入口(809),以及隔室出口(807),以允许填充和 与设置在身体(801)中的吸入通道(808)流体连通。 在使用中,患者相对于身体(801)相对于身体(801)滑动,其中药筒粉末隔室(805)中的入口被包含在身体(801)中的壁被阻塞和密封, 吸入位置,其中隔室入口变得可用于容纳在其中包含的颗粒的分散体中使用的空气,并且隔室出口(807)变得与主体(801)中的吸入通道(808)对准,以允许夹带 剂量在吸入期间分散通过装置并进入所需的作用位置。 在筒式粉末隔室中添加一个或多个侧向通风口(809)引起湍流和涡流模式,其促进改进的分散和夹带。 本发明提供了用于递送高剂量吸入药物的非常经济且简单的装置。
    • 25. 发明公开
    • INHALER
    • 气雾
    • EP3019225A1
    • 2016-05-18
    • EP14738492.9
    • 2014-07-10
    • Liita Holdings Ltd.
    • OHRT, MartinPAUSTIAN, JeppeJENSEN, Søren Dyring
    • A61M15/00A61K33/14A61K9/00
    • A61M15/0065A61K9/0075A61K9/16A61K33/14A61M15/0003A61M15/0023A61M15/0028A61M15/0086A61M15/0096A61M2202/0468A61M2202/064
    • An inhaler (1) for halotherapy has in an axial direction (A) a proximal end (P) for insertion into the mouth of a user, and a distal end (D) opposite to the proximal end, wherein the inhaler comprises an inlet (4), an outlet (5) arranged at the proximal end, an air passage (10, 11, 12, 13) extending from the inlet to the outlet, and a reservoir (8, 9) communicating with the air passage through a release orifice (6, 7). The reservoir contains a dispersible substance, such as micronized salt. The inhaler has a proximal part (2) comprising the outlet, and a distal part (3) attached to the proximal part, wherein the proximal part is slidable in the axial direction with respect to the distal part between an 'OPEN' position and a 'CLOSED' position. The inhaler further comprises an inlet valve member (14), an outlet valve member (15), and a reservoir valve member (16, 17). The inlet valve member, outlet valve member and reservoir valve member are arranged so as to simultaneously close the inlet, the outlet, and the release orifice when the proximal part is brought from the 'OPEN' position into the 'CLOSED' position, and to simultaneously open the inlet, open the outlet, and deliver an amount of the dispersible substance from the reservoir through the release orifice to the air passage when the proximal part is brought from the 'CLOSED' position into the 'OPEN' position.
    • 提供了一种用于卤疗的吸入器,其具有在轴向方向上的近端,用于插入使用者的口中,以及与近端相对的远端,其中吸入器包括入口,布置在近端的出口,空气 通道从入口延伸到出口,以及储存器,其通过释放孔与空气通道连通,所述储存器包含可分散物质。