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21. 发明授权

EP3002023B1 INHALER 有权
公开(公告)号：EP3002023B1
公开(公告)日：2017-05-31
申请号：EP15194896.5
申请日：2010-01-25
申请人： Vectura Delivery Devices Limited
发明人： SARKAR, Matthew , MILIVOJEVIC, Ivan , CLARKE, Roger , WILLIAMSON, Emma
IPC分类号： A61M15/00
CPC分类号： A61M15/0028 , A61M15/0026 , A61M15/0038 , A61M15/0091 , A61M15/0093 , A61M2202/064 , A61M2206/16

22. 发明授权

EP1670532B1 UNIT DOSE CARTRIDGE AND DRY POWDER INHALER 有权转让
标题翻译：单位剂量筒和干粉吸入器
公开(公告)号：EP1670532B1
公开(公告)日：2017-05-31
申请号：EP04783061.7
申请日：2004-09-03
申请人： MannKind Corporation
发明人： STEINER, Solomon, S. , POOLE, Trent, A. , FOG, Per, B. , POHL, Roderike , CRICK, Michael , FELDSTEIN, Robert
IPC分类号： A61M15/00
CPC分类号： A61M15/0015 , A61M15/002 , A61M15/0023 , A61M15/0025 , A61M15/0028 , A61M15/0086 , A61M16/0495 , A61M16/0825 , A61M2202/064 , A61M2205/43

23. 发明公开

EP3160553A2 METHOD AND DEVICE FOR VAPORIZATION AND INHALATION OF ISOLATED SUBSTANCES 有权
标题翻译：方法和设备的扩张和吸入分离的物质的
公开(公告)号：EP3160553A2
公开(公告)日：2017-05-03
申请号：EP15756490.7
申请日：2015-06-30
申请人： Syqe Medical Ltd.
发明人： DAVIDSON, Perry , SCHORR, Aaron , KROLL, Asaf , SCHWARTZ, Binyamin
IPC分类号： A61M11/04 , A61M15/00 , A61M16/20 , A24F47/00 , A61J1/03
CPC分类号： A61M15/002 , A24F47/008 , A61K9/007 , A61K9/0073 , A61K31/05 , A61K31/352 , A61K31/465 , A61K36/185 , A61K36/81 , A61M11/02 , A61M11/041 , A61M11/042 , A61M15/0001 , A61M15/0003 , A61M15/0013 , A61M15/0015 , A61M15/0021 , A61M15/0028 , A61M15/0045 , A61M15/005 , A61M15/0051 , A61M15/0065 , A61M15/0066 , A61M15/0091 , A61M15/06 , A61M16/14 , A61M16/20 , A61M2205/0216 , A61M2205/3303 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368 , A61M2205/3569 , A61M2205/3592 , A61M2205/36 , A61M2205/502 , A61M2205/52 , H05B1/025
摘要： Devices and methods are described for preparing, managing, and/or administering metered doses of substances for vaporized administration. In some embodiments, dose cartridges comprising at least one botanical substance include a heating element integrated into the cartridge in close contact with the botanical substance. In some embodiments, cartridge-mounted doses are stored in a magazine, optionally in carousel form, before use. Transport of a cartridge from a magazine to an electrically operated vaporizing chamber which activates the heating element is provided by a mechanical pickup means.
摘要翻译：设备和方法被描述用于制备，管理，和/或施用计量剂量的用于汽化的施用物质。在一些实施方案中，剂量药筒，其包含至少一个植物物质包括集成到与植物物质紧密接触的盒的加热元件。在一些实施例中，盒安装剂量被存储在一本杂志，任选地在圆盘传送带的形式，在使用前。从杂志盒的运输到在电气操纵蒸发室哪激活由机械拾取所提供的加热元件的装置。

24. 发明公开

EP3041555A4 DRY-POWDER INHALER AND METHOD 无效
标题翻译： TROCKENPULVERINHALATOR UND VERFAHREN
公开(公告)号：EP3041555A4
公开(公告)日：2017-03-08
申请号：EP14841987
申请日：2014-08-26
申请人： 3M INNOVATIVE PROPERTIES CO
发明人： STEIN STEPHEN W , WANG ZHAOLIN
IPC分类号： A61M15/00 , A61M16/00
CPC分类号： A61M15/0005 , A61M11/002 , A61M15/0021 , A61M15/0028 , A61M15/0043 , A61M15/0091 , A61M2202/064 , A61M2202/066 , A61M2206/10 , A61M2209/02

25. 发明公开

EP3117858A1 NEBULIZER FOR INFANTS AND RESPIRATORY COMPROMISED PATIENTS 审中-公开
标题翻译： VERNEBLERFÜRSÄUGLINGEUND PATITENTEN MITATEMWEGSBEEINTRÄCHTIGUNG
公开(公告)号：EP3117858A1
公开(公告)日：2017-01-18
申请号：EP16183458.5
申请日：2010-07-01
申请人： MicroDose Therapeutx, Inc.
发明人： GUMASTE, Anand , FLEMING, Scott , CHAN, Phiip
IPC分类号： A61M11/00 , B05B17/06 , A61M15/00 , A61M16/00 , A61M16/06 , A61M16/20
CPC分类号： A61M11/005 , A61M15/0028 , A61M15/0085 , A61M16/024 , A61M16/06 , A61M16/208 , A61M2016/0021 , A61M2016/0027 , A61M2205/50 , A61M2205/502 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/59 , A61M2205/8206 , B05B17/0607
摘要： A nebulizer device for delivering medication to infants and respiratory compromised patients includes a housing (12) defining an aerosol chamber (23) into which an aerosolized medication may be introduced, an outlet (14) for said chamber (23), a mask (26) surrounding the outlet (14), at least in part and a nebulizer for aerosolizing a medication and introducing the medication into the chamber (23).
摘要翻译：一种用于将药物输送给婴儿和呼吸系统受损的患者的雾化器装置包括限定气溶胶室（23）的壳体（12），可以引入气雾化药物，用于所述腔室（23）的出口（14），掩模（26）），至少部分地包括用于使药物雾化并将药物引入所述腔室（23）的喷雾器。

26. 发明公开

EP3116569A1 ACTIVE DRY POWDER INHALER 有权
标题翻译： INHALATORFÜRAKTIVES TROCKENPULVER
公开(公告)号：EP3116569A1
公开(公告)日：2017-01-18
申请号：EP15715459.2
申请日：2015-03-10
申请人： Inspiro Medical Ltd.
发明人： KAUFMANN, Nimrod
IPC分类号： A61M15/00
CPC分类号： A61M15/0041 , A61M11/02 , A61M15/0003 , A61M15/002 , A61M15/0028 , A61M15/0036 , A61M2016/0021 , A61M2202/064 , A61M2205/3334 , A61M2205/502 , A61M2206/16 , A61M2230/205 , A61M2230/30 , A61M2230/005
摘要： A method of flowing a medicament comprising dry powder using gas, including preparing a medicament capsule with designated inflow and outflow apertures, introducing a volume of a gas to within a medicament capsule according to one or more release conditions, and releasing a therapeutically effective amount of said powder using said gas. In some embodiments, the medicament capsule apertures are prepared and/or gas delivered to it so that deagglomeration potentially occurs largely within the energetic flow conditions of the capsule, without significant trapping of residual powder by structures such as aperture edge irregularities.
摘要翻译：一种使用气体流动包含干粉的药物的方法，包括制备具有指定的流入和流出孔的药物胶囊，根据一种或多种释放条件将一定体积的气体引入药物胶囊内，并释放治疗有效量的所说的粉末使用所说的气体。在一些实施方案中，制备药物胶囊孔口和/或将气体输送到其中，使得解聚集潜在地在胶囊的能量流动条件下潜在地发生，而不会通过诸如孔边缘不规则性的结构显着捕获残留的粉末。

27. 发明公开

EP3099364A1 POWDER COMPARTMENT FOR HIGH DOSAGE DRUG DELIVERY 有权
标题翻译： PULVERKAMMERFÜRHOCHDOSIERTE WIRKSTOFFFREISETZUNG
公开(公告)号：EP3099364A1
公开(公告)日：2016-12-07
申请号：EP16722343.7
申请日：2016-04-28
申请人： Hovione Technology Limited
发明人： VENTURA, Joao , VILLAX, Peter , FARIA, Cristina
IPC分类号： A61M15/00
CPC分类号： A61M15/002 , A61K9/0075 , A61M15/0021 , A61M15/0028 , A61M15/0043 , A61M15/0086 , A61M2202/064
摘要： A dry powder inhaler for pulmonary or nasal use, comprising at least an inhaler body 801 and a cartridge 803 with at least one powder compartment 805 including one dose of a drug. The body has an opening 804 shaped for receiving the cartridge 803 and the means to allow a controlled sliding movement of the cartridge 803 relative to the body 801 after mounting. The cartridge powder compartment 805 comprises at least two inlets or slits 806, 809, at least one of which is a side inlet 809, for the admission of air, and a compartment outlet 807 to allow filling and fluid communication with an inhalation channel 808 provided in the body 801. In use, the patient slides the cartridge 803 relative to the body 801 from the storage position, where the inlets in the cartridge powder compartment 805 are blocked and sealed by walls comprised in the body 801, into the inhalation position, where the compartment inlets become available for the admission of air used in the dispersion of the particles there contained and the compartment outlet 807 becomes aligned with the inhalation channel 808 in the body 801 to allow the entrainment of the dose dispersed through the device and into the desired site of action during inhalation. The addition of one or more lateral vents 809 in the cartridge powder compartments induces a turbulent and swirling flow pattern that promotes improved dispersion and entrainment. The invention affords a very economical and simple device for the delivery of high dosages of inhaled medicines.
摘要翻译：一种用于肺或鼻用的干粉吸入器，至少包括吸入器主体（801）和具有至少一个包含一剂药物的粉末隔室（805）的药筒（803）。主体具有形状用于接收盒（803）的开口（804）和用于在安装之后允许盒（803）相对于主体（801）受到控制的滑动运动的装置。墨粉盒隔室（805）包括至少两个入口或狭缝（806,809），其至少一个是用于容纳空气的侧入口（809），以及隔室出口（807），以允许填充和与设置在身体（801）中的吸入通道（808）流体连通。在使用中，患者相对于身体（801）相对于身体（801）滑动，其中药筒粉末隔室（805）中的入口被包含在身体（801）中的壁被阻塞和密封，吸入位置，其中隔室入口变得可用于容纳在其中包含的颗粒的分散体中使用的空气，并且隔室出口（807）变得与主体（801）中的吸入通道（808）对准，以允许夹带剂量在吸入期间分散通过装置并进入所需的作用位置。在筒式粉末隔室中添加一个或多个侧向通风口（809）引起湍流和涡流模式，其促进改进的分散和夹带。本发明提供了用于递送高剂量吸入药物的非常经济且简单的装置。

28. 发明授权

EP2736814B1 EINWEGAMPULLE ZUM EINSETZEN IN EINEN AEROSOLERZEUGER 有权
标题翻译：一次性试剂盒用于插入的烟雾发生器
公开(公告)号：EP2736814B1
公开(公告)日：2016-10-12
申请号：EP12720907.0
申请日：2012-05-16
申请人： PARI Pharma GmbH
发明人： GALLEM, Thomas , HETZER, Uwe
IPC分类号： B65D1/09 , B65D81/32 , A61M15/00
CPC分类号： B65D51/24 , A61M11/005 , A61M15/0003 , A61M15/0028 , A61M15/0036 , A61M15/0085 , A61M2207/00 , A61M2210/0618 , A61M2210/1039 , B65D1/09 , B65D1/095 , B65D81/3211 , B65D81/3277

29. 发明授权

EP2340865B1 Nasal delivery device 有权
标题翻译：鼻腔给药装置
公开(公告)号：EP2340865B1
公开(公告)日：2016-07-20
申请号：EP10011951.0
申请日：2000-03-03
申请人： Optinose AS
发明人： Djupesland, Per Gisle
IPC分类号： A61M15/00 , A61M15/08 , A61M11/02 , A61M16/00 , A61M11/06
CPC分类号： A61M3/0233 , A61M3/0279 , A61M15/0018 , A61M15/002 , A61M15/0021 , A61M15/0028 , A61M15/0045 , A61M15/0065 , A61M15/009 , A61M15/0091 , A61M15/0098 , A61M15/08 , A61M16/0866 , A61M16/1055 , A61M16/1065 , A61M2202/0468 , A61M2202/064 , A61M2205/43 , A61M2205/59 , A61M2206/10 , A61M2206/14 , A61M2210/0618 , A61M2210/0625

30. 发明公开

EP3019225A1 INHALER 有权
标题翻译：气雾
公开(公告)号：EP3019225A1
公开(公告)日：2016-05-18
申请号：EP14738492.9
申请日：2014-07-10
申请人： Liita Holdings Ltd.
发明人： OHRT, Martin , PAUSTIAN, Jeppe , JENSEN, Søren Dyring
IPC分类号： A61M15/00 , A61K33/14 , A61K9/00
CPC分类号： A61M15/0065 , A61K9/0075 , A61K9/16 , A61K33/14 , A61M15/0003 , A61M15/0023 , A61M15/0028 , A61M15/0086 , A61M15/0096 , A61M2202/0468 , A61M2202/064
摘要： An inhaler (1) for halotherapy has in an axial direction (A) a proximal end (P) for insertion into the mouth of a user, and a distal end (D) opposite to the proximal end, wherein the inhaler comprises an inlet (4), an outlet (5) arranged at the proximal end, an air passage (10, 11, 12, 13) extending from the inlet to the outlet, and a reservoir (8, 9) communicating with the air passage through a release orifice (6, 7). The reservoir contains a dispersible substance, such as micronized salt. The inhaler has a proximal part (2) comprising the outlet, and a distal part (3) attached to the proximal part, wherein the proximal part is slidable in the axial direction with respect to the distal part between an 'OPEN' position and a 'CLOSED' position. The inhaler further comprises an inlet valve member (14), an outlet valve member (15), and a reservoir valve member (16, 17). The inlet valve member, outlet valve member and reservoir valve member are arranged so as to simultaneously close the inlet, the outlet, and the release orifice when the proximal part is brought from the 'OPEN' position into the 'CLOSED' position, and to simultaneously open the inlet, open the outlet, and deliver an amount of the dispersible substance from the reservoir through the release orifice to the air passage when the proximal part is brought from the 'CLOSED' position into the 'OPEN' position.
摘要翻译：提供了一种用于卤疗的吸入器，其具有在轴向方向上的近端，用于插入使用者的口中，以及与近端相对的远端，其中吸入器包括入口，布置在近端的出口，空气通道从入口延伸到出口，以及储存器，其通过释放孔与空气通道连通，所述储存器包含可分散物质。

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