专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明授权

EP3323813B1 HISTONE ACETYLTRANSFERASE MODULATORS AND USES THEREOF 有权
公开(公告)号：EP3323813B1
公开(公告)日：2020-08-26
申请号：EP17207865.1
申请日：2011-12-22
申请人： The Trustees of Columbia University in the City of New York
发明人： Francis, Yitshak , Fa, Mauro , Arancio, Ottavio , Fiorito, Jole , Deng, Shixian , Landry, Donald W. , Luzac, Michal , Feng, Yan
IPC分类号： C07D265/14 , C07C217/22 , C07C217/58 , C07C235/60 , C07C235/64 , C07D265/36 , C07C251/24 , C07D209/48 , C07D295/088 , A61K31/167 , A61P25/28

12. 发明公开

EP3395804A1 NOVEL SPIROQUINONE DERIVATIVE COMPOUND, PRODUCTION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NEUROLOGICAL DISORDERS WHICH CONTAINS SAME AS ACTIVE INGREDIENT 有权
公开(公告)号：EP3395804A1
公开(公告)日：2018-10-31
申请号：EP17849145.2
申请日：2017-09-08
申请人： Gachon University of Industry-Academic Cooperation Foundation , Gil Medical Center
发明人： KIM, Mi-hyun , KIM, Sun Yeou , LEE, Sang-Yoon , ARRAMSHETTI, Venkanna , KIM, Kang , CHO, Kyohee , LAMA, Prema Dhorma
IPC分类号： C07D265/14 , A61K31/537 , A23L33/10
摘要： The present invention relates to a novel spiroquinone derivative compound, a production method thereof, and a pharmaceutical composition for preventing or treating neurological disorders which contains the compound as an active ingredient, and it has been confirmed that the novel spiroquinone derivative compound according to the present invention, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof may excellently suppress 'microglial activation' and shows excellent inhibition activity against acetylcholinesterase, JNK1, JNK2 and JNK3, and in addition to this, significant enzyme inhibition activity has been confirmed in a neurological diseases-related enzyme group, RIPK5, CDK3/cyclin E, PKN2/PRK2, Haspin, STK25/YSK1, ARK5/NUAK1, PKCb2, CDK2/cyclin O, DAPK1, PKCa, CDK1/cyclin B, MST3/STK24 and TLK1 and it has been confirmed that cell death suppression effect may be exhibited, and thus the novel spiroquinone derivative compound according to the present invention, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof can be usefully used for a pharmaceutical composition for preventing or treating neurological disorders or health functional food composition for preventing or improving neurological disorders by being contained therein as an active ingredient.

13. 发明授权

EP1314755B1 Ultraviolet radiation absorbents for thermoplastic polymers and methods of producing the same 有权
标题翻译：对于它们的制备热塑性聚合物和方法紫外线吸收剂
公开(公告)号：EP1314755B1
公开(公告)日：2010-09-08
申请号：EP02258010.4
申请日：2002-11-20
申请人： Takemoto Yushi Kabushiki Kaisha , Teijin Dupont Films Japan Limited
发明人： Osaki, Tatsuhiko, c/o Takemoto Yushi , Ichihashi, Tetsuo, c/o Teijin DuPont Films
IPC分类号： C08K5/357 , C07D265/14
CPC分类号： C07D265/14 , C08K5/357

14. 发明授权

EP1366053B1 FLAME-PROOFING AGENTS 有权
标题翻译：手段的闪存保护
公开(公告)号：EP1366053B1
公开(公告)日：2005-01-05
申请号：EP01273295.4
申请日：2001-11-20
申请人： Huntsman Advanced Materials (Switzerland) GmbH
发明人： WEIDMANN, Ulrich , MAGENDIE, Franck
IPC分类号： C07F9/6571 , C07D265/14 , C07D265/20 , C08K5/00
CPC分类号： C08K5/5313 , C07F9/657172
摘要： Compounds of formula (I) or (II), wherein R1 is C1-C18alkyl; C5-C12cycloalkyl that is unsubstituted or substituted by one or more C1-C6alkyl groups or C1-C6alkoxy groups; C5-C22aryl that is unsubstituted or substituted by one or more C1-C6alkyl groups or C1-C6alkoxy groups; or C7-C30aralkyl that is unsubstituted or substituted by one or more C1-C6alkyl groups or C1-C6alkoxy groups, and the radicals R2 to R13 are each independently of the others hydrogen; -NO2; dialkylamino; alkylthio; alkylsulfonyl; halogen; C1-C18alkyl; C1-C18alkoxy; C1-C18alkoxyalkyl; C5-C12cycloalkyl that is unsubstituted or substituted by one or more C1-C6alkyl groups or C1-C6alkoxy groups; C5-C22aryl that is unsubstituted or substituted by one or more C1-C6alkyl groups or C1-C6alkoxy groups; or C7-C30aralkyl that is unsubstituted or substituted by one or more C1-C6alkyl groups or C1-C6alkoxy groups, are suitable as flame-proofing agents for thermoplastic or thermosetting polymers.

15. 发明公开

EP0187329A1 Chromogene 3,1-Benzoxazine 失效
标题翻译：染色体3,1-苯并恶嗪。
公开(公告)号：EP0187329A1
公开(公告)日：1986-07-16
申请号：EP85116194.3
申请日：1985-12-18
申请人： BAYER AG
发明人： Berneth, Horst, Dr.
IPC分类号： B41M5/12 , C07D265/14 , C07D413/04 , C07D413/06 , C07D413/10 , C07D413/14 , C07C103/30
CPC分类号： C09B11/04 , B41M5/136 , B41M5/323 , C07D265/16 , C07D413/04 , C09B11/02
摘要： Als Farbbildner für druck-, wärme- und elektrosensitive Aufzeichnungsmaterialien mit saurem Entwickler eignen sich hervorragend Verbindungen der Formel
worin Z 1 Wasserstoff, Alkyl, Cycloalkyl oder
R 1 Wasserstoff, Alkyl, Cycloalkyl, Aralkyl, Aryl, Heteroalkyl oder Heteryl, X 1 , X 2 und X 3 Wasserstoff, Halogen, Alkyl, Cycloalkyl, Aryl, Alkanoylamino, Aroylamino, Heteryl und wenigstens einer dieser Reste NY 1 Y 2 , OY 3 oder SY 3 , Y', Y 2 und Y 3 Wasserstoff, Alkyl, Cycloalkyl, Aralkyl, Aryl oder Heteryl und Y 1 + Y 2 die restlichen Glieder eines gegebenenfalls weitere Heteroatome enthaltenden 5- oder 6-gliedrigen Ringes bedeuten. Man erhält farbstarke und lichtechte Kopien.
摘要翻译：正如前对压力 - ，热和电敏记录材料的彩色与下式的酸性显影剂特别适合的化合物其中Z是氢，烷基，环烷基，或 R是氢，烷基，环烷基，芳烷基。芳基，杂烷基或heteryl，X 1，X 2和X 3是氢，卤素，烷基，环烷基，芳基，烷酰基氨基，芳酰基氨基，heteryl，和这些基团NY¹Y²，OY³或SY³，Y 1，Y 2和中的至少一个Y 3是氢，烷基，环烷基，芳烷基，芳基或heteryl Y 1和Y +任选含有另外的杂原子的其余成员意味着5-或6-元环。产生强烈的光 - 快速复制。

16. 发明授权

EP2831052B1 BENZOXAZINES AND COMPOSITIONS CONTAINING THE SAME 有权
标题翻译：苯并恶嗪及含有该化合物的组合物
公开(公告)号：EP2831052B1
公开(公告)日：2017-06-14
申请号：EP13713697.4
申请日：2013-03-19
申请人： Cytec Technology Corp.
发明人： WARD, Steven, Richard , HARRIMAN, Mark, Edward
IPC分类号： C07D265/14 , C08K5/357 , C08J5/24 , C07D265/16
CPC分类号： C08G73/0233 , C07D265/16 , C08G14/06 , C08G59/00 , C08J5/24 , C08K5/357 , C08L61/34 , C08L79/02

17. 发明授权

EP1638928B1 N-ALKYNYL-2-(SUBSTITUTED ARYLOXY)ALKYLTHIOAMIDE DERIVATIVES AS FUNGICIDES 有权
标题翻译： N-炔基-2-（取代的芳氧基）ALKYLTHIOAMIDE衍生物作为杀真菌剂
公开(公告)号：EP1638928B1
公开(公告)日：2010-09-29
申请号：EP04735260.4
申请日：2004-05-28
申请人： Syngenta Limited
发明人： CROWLEY, Patrick Jelf, Syngenta Limited , SALMON, Roger, Syngenta Limited , SAGEOT, Olivia Anabelle, Syngenta Limited , BACON, David Philip, Syngenta Limited , LANGFORD, David William, Syngenta Limited
IPC分类号： C07C323/22 , C07C323/29 , C07D285/00 , C07D265/14 , C07D271/12 , C07D215/02 , C07D235/06 , C07D213/16 , A01N43/40
CPC分类号： C07D215/20 , C07C317/46 , C07C323/60 , C07D213/65 , C07D213/68 , C07D217/02 , C07D231/56 , C07D239/74 , C07D261/20 , C07D271/12 , C07D277/62 , C07D277/68 , C07D277/82
摘要： Fungicidal compounds of the general formula (1), wherein Ar is a group of the formula (A), (B1), (B2) or (C), or Ar is a 5- or 6-linked group of the formula (D1) or (D2); and R1, R2, R3, R4, R5, n, A1, A2, A3, A4, A5, Ka, Kb, L, M, V, W, X,Y and Z have the definitions given in claim 1.

18. 发明公开

EP1874743A2 PURIFIED FORM OF TANAPROGET 有权
标题翻译： TANAPROGET的净化形式
公开(公告)号：EP1874743A2
公开(公告)日：2008-01-09
申请号：EP06769890.2
申请日：2006-04-26
申请人： Wyeth
发明人： CHATLAPALLI, Ramarao , NAGI, Arwinder , POTOSKI, John , HELOM, Jean, Louise , WILK, Bogdan, Kazimierz , RUBEZHOV, Arkadiy, Zinoviy , DRAGAN, Vladimir
IPC分类号： C07D265/14 , C07D413/04 , A61K31/536 , A61P15/00
CPC分类号： C07D265/14 , C07D413/04
摘要： Micronized tanaproget, purified tanaproget Form I, and micronized, purified tanaproget Form I are provided. Also provided are compositions containing one or more of the prepared tanaproget forms, methods of using one or more of the prepared tanaproget forms, and kits containing one or more of the prepared tanaproget forms.
摘要翻译：提供微粉化的tanaproget，纯化的tanaproget I型和微粉化纯化的tanaproget I型。还提供了含有一种或多种制备的tanaproget形式的组合物，使用一种或多种制备的tanaproget形式的方法和含有一种或多种制备的tanaproget形式的试剂盒。

19. 发明公开

EP1457548A1 Oxazines as such and as dispersants in lubricating compositions 审中-公开
标题翻译：奥卡津嗪在Schmiermittelzusammensetzungen的Dispergentien
公开(公告)号：EP1457548A1
公开(公告)日：2004-09-15
申请号：EP03254549.3
申请日：2003-07-21
申请人： Infineum International Limited
发明人： Gutierrez, Antonio
IPC分类号： C10M133/48 , C07D265/12 , C07D265/14
CPC分类号： C07D265/12 , C10M133/08 , C10M133/48 , C10M135/32 , C10M169/04 , C10M2215/042 , C10M2215/225 , C10M2215/28 , C10M2217/043 , C10M2219/09 , C10N2230/04
摘要： Low molecular weight oxazine ring-containing Mannich base condensates of hydroxy aromatic compounds, aldehyde; and amine. Such compounds are useful as soot dispersants in lubricating oils when used alone, or in combination with high molecular weight dispersants.
摘要翻译：低分子量恶嗪环的曼尼希碱缩合物的羟基芳族化合物，醛; 和胺。这些化合物可用作单独使用的润滑油中的烟灰分散剂，或与高分子量分散剂组合使用。

20. 发明公开

EP1306373A4 3,4-DIHYDROISOQUINOLINE DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THESE COMPOUNDS AS THE ACTIVE INGREDIENT 有权
标题翻译： 3,4-DIHYDROISOQUINOLINDERIVAT化合物及其化合物作为活性成分配合药物
公开(公告)号：EP1306373A4
公开(公告)日：2004-09-01
申请号：EP01953336
申请日：2001-07-30
申请人： ONO PHARMACEUTICAL CO
发明人： OGAWA MIKIO , TAKAOKA Y , OHHATA AKIRA
IPC分类号： A61K31/472 , A61K31/4725 , A61P11/06 , A61P17/00 , A61P25/04 , A61P27/16 , A61P29/00 , A61P37/04 , A61P37/06 , A61P37/08 , C07D217/16 , C07D217/18 , C07D221/20 , C07D265/14 , C07D401/04 , C07D401/06 , C07D405/04 , C07D405/06 , C07D409/06 , C07D413/06 , C07D417/06 , C07D471/04 , C07D491/04 , C07D491/10 , C07D491/107 , C07D495/04 , A61K31/435 , A61K31/495 , C07D265/16 , C07D471/10
CPC分类号： C07D221/20 , A61K31/472 , A61K31/4725 , C07D217/16 , C07D217/18 , C07D265/14 , C07D401/04 , C07D401/06 , C07D405/04 , C07D405/06 , C07D409/06 , C07D413/06 , C07D417/06 , C07D471/04 , C07D491/04 , C07D491/10 , C07D495/04
摘要： 3,4-Dihydroisoquinoline derivative compounds represented by the following general formula (I) (wherein each symbol has the meaning as specified in the description) or nontoxic salts thereof. Because of having a CB2 receptor agonist activity, the compounds represented by the general formula (I) are useful in preventing and/or treating various diseases, for example, asthma, nasal allergy, atopic dermatitis, autoimmune diseases, rheumatish, immnodeficiency, postoperative pain and carcinomatous pain.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式