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11. 发明授权

EP3169324B1 MICROBICIDAL COMPOSITION COMPRISING AN OCTOXYNOL AND A QUINOLIZIDINE ALKALOID COMPOUND OR A SOURCE THEREOF 有权转让
公开(公告)号：EP3169324B1
公开(公告)日：2019-05-08
申请号：EP15822892.4
申请日：2015-07-10
申请人： Orion Biotechnology Canada Ltd.
发明人： ZHANG, Xuewu , LEIRE, Eric
IPC分类号： A61K31/4375 , A61K31/085 , A61K31/4166 , A61K36/489 , A61K36/886 , A61P15/00 , A61K45/06

12. 发明公开

EP3456336A1 COMPOUND CELERY SEED AND SOPHORA FLOWER BUD EXTRACT AND MEDICAL USE THEREOF 有权转让
公开(公告)号：EP3456336A1
公开(公告)日：2019-03-20
申请号：EP17795603.4
申请日：2017-05-12
申请人： Beijing Humanwell Junwei Pharmaceutical Tech Co., Ltd.
发明人： GAO, Yongliang , ZHANG, Bing , CHEN, Haisheng , SUN, Jianning , LU, Yanwei , LIN, Zhijian , LIU, Weixin , ZUO, Conglin , WANG, Xuezhi , WANG, Huixia. , ZHAO, Jing. , SUN, Yunxia
IPC分类号： A61K36/489 , A61K36/23 , A61P19/06
摘要： Disclosed are a compound celery seed and sophora flower bud extract and the medical use thereof, wherein the compound celery seed and sophora flower bud extract is obtained by extracting celery seed and sophora flower bud with an alcohol solvent. The extract has the effect of decreasing uric acid, can prevent or treat gout induced by hyperuricemia, and can be prepared into many kinds of preparations for oral administration.

13. 发明公开

EP2858658A4 METHODS AND COMPOSITIONS FOR IMPROVING GUT MICROBIOTA POPULATION 有权转让
标题翻译：方法和组合物改善肠道生物群落
公开(公告)号：EP2858658A4
公开(公告)日：2016-05-04
申请号：EP13799987
申请日：2013-06-04
申请人： UNIV SHANGHAI JIAOTONG , PERFECT CHINA CO LTD
发明人： ZHAO LIPING , ZHANG XU , ZHANG MENGHUI , ZHAO YUFENG , PANG XIAOYAN , ZHANG XIAOJUN , WANG LINGHUA , NING GUANG , LI XIAOYING , ZHANG YIFEI
IPC分类号： A61K36/8964 , A61K36/185 , A61K36/288 , A61K36/29 , A61K36/42 , A61K36/489 , A61K36/515 , A61K36/539 , A61K36/708 , A61K36/718 , A61K36/744 , A61K36/756 , A61P1/00
CPC分类号： A61K31/4375 , A23L33/105 , A23L33/30 , A23V2002/00 , A61K35/74 , A61K35/741 , A61K35/745 , A61K36/185 , A61K36/28 , A61K36/288 , A61K36/29 , A61K36/42 , A61K36/48 , A61K36/489 , A61K36/515 , A61K36/53 , A61K36/539 , A61K36/59 , A61K36/70 , A61K36/708 , A61K36/71 , A61K36/718 , A61K36/74 , A61K36/744 , A61K36/75 , A61K36/756 , A61K36/88 , A61K36/8964 , C12Q1/689 , C12Q2600/136 , G01N33/5088 , G01N2500/10 , A61K2300/00
摘要： A method and a composition for improving gut micro biota structure, selectively increase a first gut microbiota population while simultaneously decrease a second gut micro biota population in a subject. The first gut micro biota population includes a short-chain fatty acid (SCFA)-producing bacterium and the second gut microbiota population includes an endotoxin-producing bacterium.

14. 发明公开

EP2716295A2 COMPOSITION COMPRISING HERBAL EXTRACTS OR FERMENTED PRODUCTS THEREOF HAVING LACTIC ACID BACTERIA FOR PREVENTING OR TREATING RESPIRATORY DISEASES 有权
标题翻译：配合中药提取物及产品组合物以及用于预防乳酸菌和呼吸系统疾病的治疗有发酵
公开(公告)号：EP2716295A2
公开(公告)日：2014-04-09
申请号：EP12792329.0
申请日：2012-05-30
申请人： Korea Institute of Oriental Medicine
发明人： MA, Jin Yeul , KIM, Dong Seon , YANG, Min Cheol , YOON, Jong Hyun
IPC分类号： A61K36/489 , A61K36/484 , A61K36/355 , A61P11/00
CPC分类号： A61K36/725 , A61K35/744 , A61K36/185 , A61K36/23 , A61K36/232 , A61K36/25 , A61K36/28 , A61K36/355 , A61K36/484 , A61K36/489 , A61K36/634 , A61K36/704 , A61K36/78 , A61K2236/19 , A61K2300/00
摘要： The present invention relates to a composition for preventing or treating respiratory diseases, and more particularly, to a pharmaceutical composition, and to a health food, comprising extracts of herbal mixtures or fermented products thereof having lactic acid bacteria as effective ingredients for preventing or treating respiratory diseases, wherein the herbal mixtures comprise: Sophora flavascens, Radix glycyrrhizae, Flos Lonicerae, Angelicae Gigantis radix, Aralia continentalis, Inula helenium, Saposhnikoviae radix, Zizyphus spinosa, Houttuynia cordata, Forsythiae fructus, Arctium lappa, Herba epimedii, ginseng, Lithospermi radix, Sanguisorbae radix, Cnidii rhizoma, Scrophulariae radix, and Polygoni cuspidati radix. The herbal extracts or fermented products thereof having lactic acid bacteria exhibit the effects of significantly lowering an airway resistance value; reducing the numbers of leukocytes, neutrophilic leukocytes, lymphocytes, eosinocytes, and basophil leukocytes to levels similar to that of a normal group; and reducing the infiltration of inflammatory cells and eosinocyte cells near AHR on lung tissues. Therefore, the herbal extracts or fermented products thereof having lactic acid bacteria may be valuably used for the prevention and/or treatment of respiratory diseases such as asthma.
摘要翻译：本发明涉及一种组合物，用于预防或治疗呼吸疾病，并且更具体地，涉及一种药物组合物，以及一种健康食品，其包含混合草药或发酵产物的提取物具有乳酸菌用于预防或治疗呼吸作为有效成分疾病，worin草药混合物包含：苦参flavascens，甘草基数金银花，当归Gigantis，长白楤木，土木香，防风基数，刺枣树，蕺，连翘，牛蒡牛蒡子，淫羊藿人参，紫草基数，地榆，川芎根茎玄参麦冬，和虎杖基数。所述草药提取物或发酵产物及其具有乳酸菌表现出显着降低的气道阻力值的影响; 减少白细胞，嗜中性白细胞，淋巴细胞，嗜酸性，嗜碱细胞和白细胞的数量，以类似于正常水平做一组; 和减少炎症细胞和细胞浸润于肺组织AHR附近嗜酸球。因此，草药提取物或发酵产物及其具有乳酸菌可有价值地用于治疗呼吸疾病的预防和/或治疗：如哮喘。

15. 发明公开

EP2444098A4 TRADITIONAL CHINESE MEDICINE COMPOSITION FOR TREATING SWINE INFLUENZA, PREPARATION METHOD AND USE THEREOF 有权转让
标题翻译：物组成TYPE中医杂志为猪流感及其制造方法和使用治疗
公开(公告)号：EP2444098A4
公开(公告)日：2013-10-23
申请号：EP10788601
申请日：2010-06-17
申请人： LIVZON PHARMACEUTICAL GROUP , NAT ENGINEERING RES CT FOR MODERNIZATION OF TRADITIONAL CHINESE MEDICINE
发明人： TAO DESHENG , ZENG YONGQING , CAO HUI , GUAN YI
IPC分类号： A61K36/896 , A61K31/12 , A61K36/11 , A61K36/185 , A61K36/19 , A61K36/232 , A61K36/282 , A61K36/288 , A61K36/315 , A61K36/34 , A61K36/355 , A61K36/484 , A61K36/489 , A61K36/534 , A61K36/70 , A61K36/78 , A61K36/88 , A61K125/00 , A61P11/00 , A61P31/16
CPC分类号： A61K36/78 , A61K31/12 , A61K36/11 , A61K36/185 , A61K36/19 , A61K36/232 , A61K36/282 , A61K36/288 , A61K36/315 , A61K36/34 , A61K36/355 , A61K36/484 , A61K36/489 , A61K36/534 , A61K36/70 , A61K36/88 , A61K36/896 , A61K2300/00
摘要： The present invention relates to a traditional Chinese medicine composition for preventing and treating swine influenza, preparation method and use thereof. The said traditional Chinese medicine composition is made from Herba Houttuyniae 21.4 wt. %, Caulis Lonicerae Japonicae 17.9 wt. %, Radix Isatidis 14.3 wt. %, Rhizoma Dryopteris Crassirhizomatis 10.7 %, Radix et Rhizoma Sophorae Tonkinensis 7.1 I wt. %, Radix Angelicae Dahuricae 7.1 wt. %, Rhizoma Paridis 7.1 wt. %, Herba Artemisiae Annuae 7.1 wt. %, and Rhizoma Iridis Tectori 7.1 wt. %.

16. 发明公开

EP2376095A4 COMBINATIONS OF HERB EXTRACTS HAVING SYNERGISTIC ANTIOXIDANT EFFECT, AND METHODS RELATING THERETO 审中-公开
标题翻译：与协合抗氧化剂活性Kung和程序中使用连接提取物作为草药组合
公开(公告)号：EP2376095A4
公开(公告)日：2012-10-31
申请号：EP09835627
申请日：2009-12-17
申请人： DIAL CORP
发明人： GE HAIYAN , SEITZ JR EARL P , DOERING THOMAS
IPC分类号： A61K36/355 , A61K36/484 , A61K36/488 , A61K36/489 , A61P17/00
CPC分类号： A61K36/489 , A61K8/97 , A61K9/0014 , A61K36/355 , A61K36/484 , A61K36/488 , A61K2800/30 , A61K2800/5922 , A61Q19/00 , A61K2300/00

17. 发明授权

EP1503777B1 7-Hydroxy chromones as potent antioxidants 有权
标题翻译： 7- Hydroxychromone作为有效的抗氧化剂
公开(公告)号：EP1503777B1
公开(公告)日：2012-08-22
申请号：EP03733934.8
申请日：2003-05-01
申请人： Unigen, Inc.
发明人： JIA, Qi , FARROW, Thomas, M.
IPC分类号： A61K31/7048 , A61K31/353 , A61K36/886 , A61K36/185 , A61K36/704 , A61K36/282 , A61K36/38 , A61K36/48 , A61K36/489 , A61K36/296 , A61P9/10 , A61P27/12 , A61P25/28 , A61P3/10 , A61P35/00
CPC分类号： A61K36/48 , A61K31/353 , A61K31/7034 , A61K31/7048 , A61K36/185 , A61K36/282 , A61K36/296 , A61K36/38 , A61K36/489 , A61K36/704 , A61K36/886
摘要： The present invention describes the identification and purification of 7-hydroxychromes that exhibit potent antioxidant activity. In one embodiment the present invention includes a method for providing an antioxidant to a host in need thereof, comprising administering an effective amount of a 7-hydroxychrome or a mixture of 7-hydroxychromones. The present invention includes methods that are effective in inhibiting free radical and oxidation caused damage through simultaneous suppression of free radical generation and the suppression of the production of reactive oxygen species (ROS). The present invention also includes methods for preventing and treating ROS mediated diseases and conditions and diseases and conditions associated with other oxidative processes. The method for preventing and treating ROS mediated diseases and conditions and diseases and conditions associated with other oxidative processes is comprised of administering to a host in need thereof an effective amount of a composition comprised of a 7-hydroxychrome or a mixture of 7-hydroxychromones and a pharmaceutically acceptable carrier. Included in this invention is an improved method to isolate and purify 7-hydroxychromones from plant sources.

18. 发明公开

EP2415469A1 Anti-Resorptive and Bone Building Dietary Supplements and Methods of Use 审中-公开
标题翻译： Antiresorptive und KnochenaufbauendeDiätnahrungszusätzeund Verfahren Zu Ihrer Verwendung
公开(公告)号：EP2415469A1
公开(公告)日：2012-02-08
申请号：EP11176493.2
申请日：2007-10-24
申请人： Krempin, David W. , Murray, Mary A. , Lin, Yumei , Gellenbeck, Kevin W. , Da Costa, Silvia R. , Wilkins, Leon M. , Roh-schmidt, Haeri , Rana, Jatinder , Rebhun, John F. , Fast, David J.
发明人： Krempin, David W. , Murray, Mary A. , Lin, Yumei , Gellenbeck, Kevin W. , Da Costa, Silvia R. , Wilkins, Leon M. , Roh-schmidt, Haeri , Rana, Jatinder , Rebhun, John F. , Fast, David J.
IPC分类号： A61K31/352 , A61K36/185 , A61K36/484 , A61K36/258 , A61K36/87 , A61K36/489 , A61P19/00 , A61P19/10
CPC分类号： A61K36/87 , A23L33/105 , A23V2002/00 , A61K31/352 , A61K36/185 , A61K36/254 , A61K36/258 , A61K36/484 , A61K36/489 , A61K36/804 , A61K2300/00
摘要： Disclosed herein are dietary supplement compositions, regimens and methods for increasing or stimulating bone growth, decreasing or preventing bone resorption, increasing bone strength, improving bone structure, and improving bone architecture comprising a first composition comprising a combination of at least two of: quercetin, Siberian ginseng, Sophora japonica , and licorice, wherein the combination of the first composition increases bone morphogenic protein-2 gene, promoter or protein expression; and a second composition comprising an extract of pomegranate in combination with at least one of green tea, grape seed, and ipriflavone, wherein the combination of the second composition inhibits the expression of RANK-L.
摘要翻译：本文公开了膳食补充剂组合物，方案和用于增加或刺激骨生长，减少或预防骨吸收，增加骨强度，改善骨结构和改善骨架构的膳食补充剂组合物，方案和方法，其包含第一组合物，其包含以下组合：槲皮素，西伯利亚人参，苦参和甘草，其中第一组合物的组合增加骨形态发生蛋白-2基因，启动子或蛋白质表达; 以及第二组合物，其包含与绿茶，葡萄籽和异黄酮中的至少一种组合的石榴提取物，其中所述第二组合物的组合抑制RANK-L的表达。

19. 发明公开

EP1707238A4 PHARMACEUTICALS OF CHINESE TRADITIONAL MEDICINE OF TREATING LUNG CANCER AND PREPARATION METHOD THEREOF 审中-公开
标题翻译：从制药中药对肺癌用于生产的热处理工艺
公开(公告)号：EP1707238A4
公开(公告)日：2009-09-09
申请号：EP03779658
申请日：2003-12-19
申请人： MING QI ONCOLOGY CHINESE MEDIC
发明人： LIU JIAXIANG , ZHOU JIANSHI
IPC分类号： A61P35/04 , A61K36/10 , A61K36/23 , A61K36/296 , A61K36/40 , A61K36/424 , A61K36/48 , A61K36/481 , A61K36/489 , A61K36/537 , A61K36/638 , A61K36/748 , A61K36/896 , A61K36/8965 , A61K36/8968
CPC分类号： A61K36/896 , A61K36/10 , A61K36/23 , A61K36/296 , A61K36/40 , A61K36/424 , A61K36/48 , A61K36/481 , A61K36/489 , A61K36/537 , A61K36/638 , A61K36/748 , A61K36/8965 , A61K36/8968 , A61K2300/00
摘要： The present invention provides a composition of treating cancer, comprising (a) pharmaceutically acceptable carriers, and (b) effective dose of water- extract or organic solvent- extract of plant materials, the plant materials including Semen Trigonellae, Astragali Radix, Glehniae Radix and Asparagi Radix. Preferably, the composition also comprises extract of other anticancer plant materials, such as Fructus Ligustri Lucidi or Herba Selaginellae Doederleinii. The present invention also provides processes of preparation for said composition and methods of treating cancer (especially lung cancer).

20. 发明授权

EP1435899B1 A COMPOSITION FOR PROMOTING HAIR GROWTH 有权
标题翻译：组合物技术促进毛发生长
公开(公告)号：EP1435899B1
公开(公告)日：2009-03-11
申请号：EP01972782.5
申请日：2001-09-28
申请人： LG Household & Health Care Ltd.
发明人： HWANG, Seong-Lok , YOON, In-Byeong , LEE, Min-Ho, 11-303 KIT Apt., , CHANG, Sug-Youn , RANG, Moon-Jeong , AHN, Ho-Jeong
IPC分类号： A61Q7/00 , A61K8/97 , A61K36/489 , A61K8/35 , A61K8/67
CPC分类号： A61Q7/00 , A61K8/35 , A61K8/4926 , A61K8/97 , A61K31/122 , A61K31/60 , A61K36/258 , A61K36/489 , A61K36/51 , A61K36/61 , A61K36/67 , A61K36/8994 , A61K45/06 , A61K2800/782 , A61K2300/00
摘要： The present invention relates to a composition for promoting hair growth. More particularly, the present invention comprises a component for inhibiting 5α -reductase activity, a functional component of cell activity, and an expansion component of peripheral blood vessels. A composition for promoting hair growth of the present invention has a superior effect on hair growth.

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