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    • 14. 发明公开
    • METHOD FOR PRODUCING A PERFLUORO COMPOUND HAVING HYDROXYL GROUPS
    • VERFAHREN ZUR HERSTELLUNG EINER PERFLUORVERBINDUNG MIT HYDROXYLGRUPPEN
    • EP2325157A1
    • 2011-05-25
    • EP09813069.3
    • 2009-09-08
    • Asahi Glass Company Limited
    • SHIRAKAWA, DaisukeGOZU, YoshiyukiMORISAWA, Yoshitomi
    • C07C41/26C07C43/13C07B61/00
    • C07C69/63C07C43/137C07C59/315C07C69/708
    • To provide a method for producing a perfluoro compound having hydroxyl groups, whereby agglomeration of a reduction reaction intermediate tends not to occur during a reduction reaction, and a perfluoro compound having -C(=O)OH can be used as a starting material.
      Reducing (A-C(=O)=Q=) n R fn in the presence of a metal hydride and an inorganic salt of lithium in an alcohol solvent to obtain
      (B-CH(OH)-Q-) n-m (A-C(=O)-Q-) m R fn , wherein A is a hydroxyl group, a C 1-5 alkoxy group, a hydrogen atom, a C 1-5 alkyl group or the like, Q is a perfluoroalkylene group or the like, n is an integer of at least 1, m is an integer at least 0 and less than n, R fn is an n valent perfluoro saturated hydrocarbon group or the like, and B is a group depending on A wherein when A is a hydroxyl group, a C 1-5 alkoxy group or the like, B is a hydrogen atom, and when A is a hydrogen atom, a C 1-5 alkyl group or the like, B is the same group as A.
    • 为了提供一种制备具有羟基的全氟化合物的方法,因此在还原反应中不会发生还原反应中间体的聚集,并且可以使用具有-C(= O)OH的全氟化合物作为原料。 在醇溶剂中,在金属氢化物和锂的无机盐存在下还原(AC(= O)= Q =)n R fn,得到(B-CH(OH)-Q-)nm(AC(= O )-Q-)m R fn,其中A是羟基,C 1-5烷氧基,氢原子,C 1-5烷基等,Q是全氟亚烷基等,n是 至少为1的整数,m为至少为0且小于n的整数,R fn为n价全氟饱和烃基等,B为取代基的A,其中当A为羟基时, C 1-5烷氧基等,B为氢原子,当A为氢原子,C 1-5烷基等时,B为与A相同的基团。