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111. 发明授权

EP3395796B1 A CRYSTALLINE TRIHYDRATE FORM OF (3S,3S') 4,4'-DISULFANEDIYLBIS (3-AMINOBUTANE 1-SULFONIC ACID) 有权转让
公开(公告)号：EP3395796B1
公开(公告)日：2021-11-24
申请号：EP18177972.9
申请日：2011-10-07
发明人： BALAVOINE, Fabrice , MADEC, Jonathan , SCHNEIDER, Jean-Marie , COQUEREL, Gérard , COUVRAT, Nicolas , CARTIGNY, Yohann , PETIT, Marie-Noëlle
IPC分类号： C07C309/14 , C07C303/02 , C07C319/24 , C07C323/66 , C07C303/22

112. 发明授权

EP3164381B1 PROCÉDÉ DE PRÉPARATION DE MÉTHYLMERCAPTAN 有权
公开(公告)号：EP3164381B1
公开(公告)日：2019-12-11
申请号：EP15736577.6
申请日：2015-06-29
申请人： Arkema France
发明人： FREMY, Georges , BARRE, Patrice , RAYMOND, Jean-Michel
IPC分类号： C07C319/02 , C07C319/24 , C01B32/75

113. 发明授权

EP3080079B1 OXIDATION OF 2-MERCAPTOETHANOL 有权
公开(公告)号：EP3080079B1
公开(公告)日：2018-07-25
申请号：EP14816166.4
申请日：2014-12-09
申请人： BASF SE
发明人： VAUTRAVERS, Nicolas , TELES, Joaquim Henrique
IPC分类号： C07C319/24 , C07C323/12 , C10M135/24
CPC分类号： C07C319/24 , C07C323/12 , C10M135/24 , C10M2219/084
摘要： The present invention relates to a process for the preparation of bis-(2-hydroxyethyl)-disulfide by oxidizing 2-mercaptoethanol with oxygen in a reaction mixture comprising at least one homogeneously distributed iron comprising salt or complex as catalyst and at least one tertiary amine, to bis-(2-hydroxyethyl)-disulfide, obtainable with the process, and to the use of this bis-(2-hydroxyethyl)-disulfide as intermediate in the manufacture of chemical compounds, such as lubricant additives and in the tertiary oil recovery.

114. 发明公开

EP2951151A1 POLYSULFIDE POLYOLS, THEIR PRODUCTION AND USE IN THE SYNTHESIS OF POLYURETHANES 审中-公开
标题翻译： POLYSULFIDPOLYOLE，生产和使用及其特性聚氨酯的生产
公开(公告)号：EP2951151A1
公开(公告)日：2015-12-09
申请号：EP14701185.2
申请日：2014-01-23
申请人： BASF SE
发明人： BALBO BLOCK, Marco , RHUDY, Kevin , FLECKENSTEIN, Christoph
IPC分类号： C07C319/24 , C08G71/04 , C08G75/14 , C08G101/00
CPC分类号： C08G18/7664 , C07C319/24 , C08G18/3865 , C08G18/3868 , C08G18/4009 , C08G18/69 , C08G2101/0025 , C08G2101/0058 , C07C321/18 , C07C321/14
摘要： The present invention relates to sulfur containing polyols, a process for their production by reaction of at least one unsaturated alcohol A with elemental sulfur, wherein the unsaturated alcohol A has only one carbon-carbon double bond-unsaturation per molecule. The sulfur containing polyols are used in the production of polyurethanes, in particular rigid foam polyurethanes, for high-temperature pipe insulation applications.

115. 发明公开

EP2664614A4 PALLADIUM-COPPER CATALYSTS FOR THE HOMOGENEOUS SELECTIVE OXIDATION OF THIOL GROUPS 审中-公开
标题翻译：钯 - 铜系催化剂选择性氧化均相巯基
公开(公告)号：EP2664614A4
公开(公告)日：2014-11-26
申请号：EP11855523
申请日：2011-12-30
申请人： IVY PHARM LTD LIABILITY COMPANY
发明人： BALAZOVSKY MARK BORISOVICH , ANTONOV VIKTOR GEORGIEVICH , BELYAEV ALEXANDR NIKOLAEVICH , EREMIN ALEXEI VLADIMIROVICH
IPC分类号： C07C319/24 , A61K31/095 , A61K31/28 , A61K31/30 , A61K38/06 , A61P7/04 , A61P31/12 , B01J23/89 , B01J31/16
CPC分类号： A61K47/48023 , A61K31/198 , A61K31/28 , A61K31/7056 , A61K31/708 , A61K33/34 , A61K38/06 , A61K45/06 , B01J31/226 , B01J2231/763 , B01J2531/0216 , B01J2531/16 , B01J2531/824 , C07C319/24 , C07C323/59 , A61K2300/00

116. 发明公开

EP2640692A1 PROCESS FOR PREPARING AZOMETHINES FROM ALPHA-OXOCARBOXYLATES, AMINES AND ARYL BROMIDES 审中-公开
标题翻译： VERFAHREN ZUR HERSTELLUNG VON AZOMETHINEN AUS ALPHA-OXOCARBOXYLATEN，AMINEN UND ARYLBROMIDEN
公开(公告)号：EP2640692A1
公开(公告)日：2013-09-25
申请号：EP11784515.6
申请日：2011-11-18
申请人： Saltigo GmbH
发明人： COTTE, Alain , GOTTA, Matthias , GOOßEN, Lukas , RUDOLPHI, Felix , SONG, Bingrui
IPC分类号： C07C249/02 , C07C319/24 , C07D213/127 , C07D213/53 , C07D307/52 , C07D333/22
CPC分类号： C07C253/00 , C07C45/42 , C07C249/02 , C07C253/30 , C07C319/20 , C07C2601/14 , C07C2603/26 , C07D213/53 , C07D307/52 , C07D333/22 , C07C251/18 , C07C251/24 , C07C255/61 , C07C323/45
摘要： A process for preparing azomethines of the general formula (V) where R is an optionally substituted carbocyclic aromatic radical having 6 to 24 carbon atoms or an optionally substituted alkyl radical or an optionally substituted heteroaromatic radical having 5 to 24 carbon atoms, and R
1 is an optionally substituted carbocyclic aromatic radical having 6 to 24 carbon atoms or an optionally substituted heteroaromatic radical having 5 to 24 carbon atoms, R
2 is hydrogen or an optionally substituted carbocyclic aromatic radical having 6 to 24 carbon atoms or an optionally substituted alkyl radical or an optionally substituted cycloalkyl radical or an optionally substituted heteroaromatic radical having 5 to 24 carbon atoms by reacting alpha-oxo carboxylates of the general formula (I) where n is a number in the range from 1 to 6, M
(n+) is a cation, with aryl bromides of the general formula (IV) and amines of the general formula (II) via the alpha-iminocarboxylate intermediate of the general formula (III), in the presence of two transition metals or compounds thereof as catalyst, is described.
摘要翻译：一种制备通式（Ⅴ）的偶氮甲碱的方法，其中R是具有6至24个碳原子的任选取代的碳环芳族基团或任选取代的烷基或任选取代的具有5至24个碳原子的杂芳基，R 1是具有6至24个碳原子的任选取代的碳环芳族基团或具有5至24个碳原子的任选取代的杂芳族基团，R 2是氢或具有6至24个碳原子的任选取代的碳环芳族基团或任选取代的烷基或任选取代的环烷基或具有5至24个碳原子的任选取代的杂芳族基团，其中通式（I）的α-氧代羧酸盐，其中n为1至6的数，M（n +）为阳离子，与通式（Ⅳ）的芳基溴化物ƒ€ƒ€€ƒ€ƒ€ƒ€ƒR 1 -Br€ƒ€ƒ€ƒ（Ⅳ）和胺通式（II）€ƒ€€ƒ€ƒ€ƒ€ƒ€ƒR 2 -NH 2€ƒ€ƒ€ƒ€ƒ（II）通过通式的α-亚氨基羧酸盐中间体（ III）在两种过渡金属或其化合物作为催化剂的存在下进行了描述。

117. 发明授权

EP1633705B1 OXIDATION VON MERCAPTOETHANOL 失效转让
标题翻译：氧化性巯基乙醇
公开(公告)号：EP1633705B1
公开(公告)日：2013-06-19
申请号：EP04724562.6
申请日：2004-03-31
申请人： Akzo Nobel N.V.
发明人： ZEITLER, Michael , KOTTNER, Nils , BERGFELD, Manfred
IPC分类号： C07C319/24
CPC分类号： B01J31/0237 , B01J27/24 , B01J31/04 , B01J31/28 , B01J31/32 , B01J2231/70 , C07C319/24 , C07C323/12

118. 发明公开

EP2569279A1 METHOD OF SYNTHESIS 有权转让
标题翻译：合成方法
公开(公告)号：EP2569279A1
公开(公告)日：2013-03-20
申请号：EP11721279.5
申请日：2011-05-13
申请人： GE Healthcare UK Limited
发明人： BRATHE, Anders , OLSSON, Andreas , THANING, Mikkel , BUGGE, Steffen
IPC分类号： C07C319/14 , C07C319/20 , C07C319/24 , C07C323/44 , C07B59/00
CPC分类号： C07C319/14 , C07B59/001 , C07B2200/05 , C07C319/20 , C07C319/24 , C07C323/44
摘要： The present invention provides a method for the preparation of a radiolabeiied guanidine derivative, in particular wherein the radiolabeiied guanidine derivative is a positron emission tomography (PET) tracer. Certain intermediates useful in said method are also provided, as well as means for carrying out said method in an automated fashion. The method of the invention provides advantages over known methods for the preparation of radiolabeiied guanidine derivatives.

119. 发明授权

EP2079686B1 GARLIC PROCESSING 有权
标题翻译：大蒜加工
公开(公告)号：EP2079686B1
公开(公告)日：2013-01-02
申请号：EP07824508.1
申请日：2007-11-09
申请人： Ecospray Limited
发明人： BLOCK, Eric , GROOM, Murree
IPC分类号： C07C319/24 , C07C321/18
CPC分类号： C07C321/18 , C07C319/24

120. 发明公开

EP2455364A1 Process for Preparing Azomethines from alpha-Oxocarboxylates, Amines and Aryl Bromides 审中-公开
标题翻译： Verfahren zur Herstellung von Azomethinen aus Alpha-Oxocarboxylaten，Aminen und Arylbromiden
公开(公告)号：EP2455364A1
公开(公告)日：2012-05-23
申请号：EP10191863.9
申请日：2010-11-19
申请人： Saltigo GmbH
发明人： Cotté, Alain , Gotta, Matthias , Goossen, Lukas , Rudolphi, Felix , Song, Bingrui
IPC分类号： C07C249/02 , C07C319/24 , C07D213/127 , C07D213/53 , C07D307/52 , C07D333/22
CPC分类号： C07C253/00 , C07C45/42 , C07C249/02 , C07C253/30 , C07C319/20 , C07C2601/14 , C07C2603/26 , C07D213/53 , C07D307/52 , C07D333/22 , C07C251/18 , C07C251/24 , C07C255/61 , C07C323/45
摘要： A process for preparing azomethines of the general formula (V)

where
R is an optionally substituted carbocyclic aromatic radical having 6 to 24 carbon atoms or an optionally substituted alkyl radical or an optionally substituted heteroaromatic radical having 5 to 24 carbon atoms, and
R 1 is an optionally substituted carbocyclic aromatic radical having 6 to 24 carbon atoms or an optionally substituted heteroaromatic radical having 5 to 24 carbon atoms,
R 2 is hydrogen or an optionally substituted carbocyclic aromatic radical having 6 to 24 carbon atoms or an optionally substituted alkyl radical or an optionally substituted cycloalkyl radical or an optionally substituted heteroaromatic radical having 5 to 24 carbon atoms

by reacting alpha-oxo carboxylates of the general formula (I)

where
n is a number in the range from 1 to 6,
M (n+) is a cation,

with aryl bromides of the general formula (IV)

R 1 -Br (IV)

and amines of the general formula (II)

R 2 -NH 2 (II)

via the alpha-iminocarboxylate intermediate of the general formula (III),

in the presence of two transition metals or compounds thereof as catalyst, is described.
摘要翻译：一种制备通式（Ⅴ）的偶氮甲碱的方法，其中R是具有6至24个碳原子的任选取代的碳环芳族基团或任选取代的烷基或任选取代的具有5至24个碳原子的杂芳基，R 1是具有6至24个碳原子的任选取代的碳环芳族基团或具有5至24个碳原子的任选取代的杂芳族基团，R 2是氢或具有6至24个碳原子的任选取代的碳环芳族基团或任选取代的烷基或任选取代的环烷基或具有5至24个碳原子的任选取代的杂芳族基团，其中通式（I）的α-氧代羧酸盐，其中n为1至6的数，M（n +）为阳离子，与通式（Ⅳ）的芳基溴化物ƒ€ƒ€€ƒ€ƒ€ƒ€ƒR 1 -Br€ƒ€ƒ€ƒ（Ⅳ）和胺通式（II）€ƒ€€ƒ€ƒ€ƒ€ƒ€ƒR 2 -NH 2€ƒ€ƒ€ƒ€ƒ（II）通过通式的α-亚氨基羧酸盐中间体（ III）在两种过渡金属或其化合物作为催化剂的存在下进行了描述。

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