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111. 发明公开

EP1545749A4 ULTRAFILTRATION MEMBRANE, DEVICE, BIOARTIFICIAL ORGAN AND METHODS 审中-公开
标题翻译：超滤膜装置，生物人工器官及方法
公开(公告)号：EP1545749A4
公开(公告)日：2009-03-18
申请号：EP03754486
申请日：2003-09-11
申请人： UNIV MICHIGAN , CLEVELAND CLINIC FOUNDATION
发明人： FISSELL WILLIAM H IV , HUMES DAVID H , ROY SHUVO , FLEISCHMAN AARON J
IPC分类号： B01D53/22 , A61B5/05 , A61M1/16 , A61M1/34 , B01D57/02 , B01D61/18 , B01D61/28 , B01D61/42 , B01D67/00 , B01D71/00 , B01D71/02 , C12N5/00 , C12N13/00 , G01N1/34 , G01N33/487
CPC分类号： B01D67/0088 , A61M1/1678 , A61M1/34 , A61M1/3403 , A61M1/3406 , A61M1/3489 , A61M2205/3331 , A61M2205/50 , B01D57/02 , B01D61/18 , B01D61/28 , B01D61/425 , B01D67/0058 , B01D67/0072 , B01D67/0086 , B01D67/0093 , B01D71/027 , B01D2323/38 , B01D2325/028 , B01D2325/28 , C12N13/00 , G01N27/3271 , G01N2001/4016
摘要： The present invention relates to ultrafiltration. In particular, the present invention provides a compact ultrafiltration device (10) and methods for generating an ultrafiltrate, both of which can be used for a variety of applications, including, but not limited to filtering blood, diagnostic applications, and as a bioreactor.

112. 发明公开

EP1973472A1 ANALYTE DETECTION SYSTEM AND METHOD WITH PERIODIC SAMPLE DRAW AND BODY FLUID ANALYZER 审中-公开
标题翻译： ANALYTENNACHWEISSYSTEM带有周期采样，津液分析仪程序
公开(公告)号：EP1973472A1
公开(公告)日：2008-10-01
申请号：EP06734992.8
申请日：2006-02-13
申请人： Optiscan Biomedical Corporation
发明人： BRAIG, James R. , RULE, Peter
IPC分类号： A61B5/15 , A61M5/172
CPC分类号： A61B5/1486 , A61B5/145 , A61B5/14532 , A61B5/14539 , A61B5/14546 , A61B5/14557 , A61B5/1495 , A61B5/15003 , A61B5/150213 , A61B5/150221 , A61B5/150229 , A61B5/150358 , A61B5/150755 , A61B5/150862 , A61B5/150992 , A61B5/153 , A61B5/155 , A61B5/157 , A61B5/4839 , A61B2562/0295 , A61M5/14232 , A61M2005/1726 , A61M2230/201 , G01N27/3271 , G01N33/49
摘要： Described is a system for analyzing a body fluid of a patient comprises a fluid transport network having a patient end configured to provide fluid communication with the body fluid in the patient and a fluid delivery point spaced from the patient end. A pump system (203) is coupled to the fluid transport network. The pump system has an infusion mode in which the pump system is operable to pump an infusion fluid toward the patient end of the fluid transport network and a draw mode in which the pump system is operable to draw the body fluid from the patient into the fluid transport network through the patient end. At least one electrochemical test element is located near the fluid delivery point of the fluid transport network. The electrochemical test element (9520) is positioned to receive a portion of the body fluid delivered to the delivery point by the fluid transport network. An analyte detection system (334) is configured to receive the test element and to measure at least one analyte in the portion of the body fluid.

113. 发明公开

EP1956525A2 Method for identifying a sample and RFID tag therefor 审中-公开
标题翻译： Verfahren zur Erkennung einer Probe und RFID-TAGdafür
公开(公告)号：EP1956525A2
公开(公告)日：2008-08-13
申请号：EP08075158.9
申请日：2006-10-27
申请人： Seiko Epson Corporation
发明人： Tam, Simon
IPC分类号： G06K19/07 , G01N33/487 , G01N35/00
CPC分类号： G01N27/3271
摘要： A method of sensing a property of each of a plurality of samples, is disclosed. The method comprises disposing a sensor chip in each sample, the sensor chip being adapted to sense the property of a respective sample and comprising sensing electronics, a wireless communication device and an identifier. Each sensor chip is then registered and sensed data is received from each of the registered sensor chips concurrently via the respective wireless communication device.
摘要翻译：一种识别样本（200）的方法，所述方法包括：从容器（X）接收识别数据，所述容器包括RFID标签（210）并被配置为存储样本，所述RFID标签被配置为存储识别数据并传输识别数据; 确定识别数据是否是新的; 并且如果识别数据是新的，则登记识别数据。

114. 发明公开

EP1939613A1 SENSOR CHIP AND METHOD FOR PRODUCING THE SAME 审中-公开
标题翻译： SENSORCHIP UND VERFAHREN ZUR HERSTELLUNG DAVON
公开(公告)号：EP1939613A1
公开(公告)日：2008-07-02
申请号：EP06811834.8
申请日：2006-10-16
申请人： Sumitomo Electric Industries, Ltd. , National Institute of Advanced Industrial Science and Technology
发明人： NAKAMURA, Hideaki , GOTOH, Masao , ISHIKAWA, Tomoko , KARUBE, Isao , HOSOYA, Toshifumi , KAIMORI, Shingo , ICHINO, Moriyasu
IPC分类号： G01N27/327
CPC分类号： G01N27/3271 , Y10T156/1051
摘要： It is intended to provide a sensor chip which has a small size and is easily produced and capable of determining quantities of at least two components of multiple samples rapidly, conveniently, and correctly as well as to provide a production method capable of producing the sensor chip easily and with high productivity.
A sensor chip includes a substrate, a cover layer, a spacer layer sandwiched between the substrate and the cover layer, multiple reaction portions disposed between the substrate and the cover layer, multiple detection units exposed in the hollow reaction portions, and a sample inlet communicated with the hollow reaction portions and a method for producing the sensor chip.
A sensor chip includes two substrates opposed to each other, a spacer layer sandwiched between the substrates, and multiple measurement units disposed between the substrates and including two or more hollow reaction portions that share one sample inlet opened on outer surfaces of the substrates and detection electrode units respectively exposed in the hollow reaction portions and a method for producing the sensor chip.
摘要翻译：本发明提供一种传感器芯片，其尺寸小，易于制造，能够快速，方便，准确地确定多个样品的至少两个组分的量，并提供能够生产传感器芯片的制造方法容易和高生产力。传感器芯片包括衬底，覆盖层，夹在衬底和覆盖层之间的间隔层，设置在衬底和覆盖层之间的多个反应部分，暴露在中空反应部分中的多个检测单元和连通的样品入口中空反应部分和传感器芯片的制造方法。传感器芯片包括彼此相对的两个基板，夹在基板之间的间隔层和设置在基板之间的多个测量单元，并且包括两个或更多个中空反应部分，其共享在基板的外表面上开放的一个样品入口和检测电极分别暴露在中空反应部分中的单元和传感器芯片的制造方法。

115. 发明公开

EP1862543A1 COENZYME-LINKED GLUCOSE DEHYDROGENASE AND POLYNUCLEOTIDE ENCODING THE SAME 有权转让
标题翻译： COENZYM-VERKNÜPFTEGLUCOSE-DEHYDROGENASE UNDDAFÜRCODIERENDES POLYNUKLEOTID
公开(公告)号：EP1862543A1
公开(公告)日：2007-12-05
申请号：EP06730146.5
申请日：2006-03-27
申请人： Ikeda Food Research Co. Ltd.
发明人： OMURA, Hironori , SANADA, Hirokazu , YADA, Takako , ATSUMI, Ayaka , MORITA, Tetsunari , ISHIMARU, Emi
IPC分类号： C12N15/09 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/04 , C12Q1/32 , C12R1/645 , C12R1/66 , C12R1/69
CPC分类号： C12Q1/006 , C12N9/0004 , C12N9/0006 , C12Q1/004 , C12Q1/32 , C12Y101/05 , C12Y101/9901 , G01N27/3271 , G01N2333/904
摘要： The present invention provides members that produce on a large scale a coenzyme-linked glucose dehydrogenase which has excellent substrate-recognizing ability toward glucose while providing low action on maltose. The present invention relates to a polynucleotide encoding a soluble coenzyme-linked glucose dehydrogenase that catalyzes the oxidation of glucose in the presence of an electron acceptor and has an activity toward maltose of 5% or lower; a polypeptide encoded by the nucleotide sequence of the polynucleotide; a recombinant vector carrying the polynucleotide; a transformed cell produced using the recombinant vector; a method for producing a polypeptide comprising culturing the transformed cell and collecting from the cultivated products a polypeptide that links to FAD to exert the glucose dehydration activity; a method for determination of glucose using the polypeptide; a reagent composition for determination of glucose; and a biosensor.
摘要翻译：本发明提供了大规模生产辅酶葡萄糖脱氢酶的成员，其对葡萄糖具有优异的底物识别能力，同时对麦芽糖提供低作用。本发明涉及编码可溶性辅酶葡萄糖脱氢酶的多核苷酸，其在电子受体的存在下催化葡萄糖的氧化并具有麦芽糖的活性为5％以下; 由多核苷酸的核苷酸序列编码的多肽; 携带多核苷酸的重组载体; 使用重组载体产生的转化细胞; 一种生产多肽的方法，包括培养转化的细胞并从培养产物中收集与FAD连接以发挥葡萄糖脱水活性的多肽; 使用多肽测定葡萄糖的方法; 用于测定葡萄糖的试剂组合物; 和生物传感器。

116. 发明公开

EP1411352A4 ANALYZING APPARATUS, PIERCING ELEMENT INTEGRALLY INSTALLED BODY FOR TEMPERATURE MEASURING DEVICE WITH ANALYZING APPARATUS, AND BODY FLUID SAMPLING APPARATUS 有权
标题翻译：分析装置，冬青元式车身安装对温度测量装置与分析装置及体液采取装置
公开(公告)号：EP1411352A4
公开(公告)日：2007-11-07
申请号：EP02745986
申请日：2002-07-11
申请人： ARKRAY INC
发明人： KATSUKI KOJI , SAKATA TETSUYA , KUSAKA YASUHIDE
IPC分类号： A61B5/00 , G01N33/487 , G01N27/327
CPC分类号： A61B5/1486 , A61B5/14532 , A61B5/150022 , A61B5/150213 , A61B5/150412 , A61B5/150503 , A61B5/15117 , A61B5/15123 , A61B5/1519 , A61B5/15194 , A61B5/157 , A61B2562/0295 , G01N27/3271
摘要： An analyzing apparatus (1A), comprising a capillary (31) formed on a substrate (2), a liquid inlet (20) for leading sample liquid into the capillary (31), and a liquid leading promoting means (6) for promoting the leading of the sample liquid from the liquid inlet (20), the liquid leading promotion means (6) further comprising at least either of an water absorbing layer higher in water absorption than the substrate (2) and a sticking layer higher in adhesiveness to skin than the substrate (2).

117. 发明授权

EP1563085B1 COOLING STATIONS FOR USE IN A WEB PRINTING PROCESS FOR THE MANUFACTURE OF ELECTROCHEMICAL SENSORS 有权
标题翻译：冷却器用在轨压力用于生产电化学传感器
公开(公告)号：EP1563085B1
公开(公告)日：2007-08-01
申请号：EP03769674.7
申请日：2003-10-30
申请人： Lifescan Scotland Ltd
发明人： DAVIES, Oliver, William, Hardwicke , HALLFORD, John, Thomas , MARSHALL, Robert , MCNEILLY, Brian, Andrew , YEUDALL, Robert, Malcolm
IPC分类号： C12Q1/00 , H05K3/12 , H05K3/46 , G01N27/30
CPC分类号： H05K3/1216 , B41M3/006 , C09D11/52 , G01N27/3271 , H05K1/0269 , H05K1/0393 , H05K1/162 , H05K2201/09918 , H05K2203/081 , H05K2203/1545 , H05K2203/166
摘要： The present invention describes a method and apparatus of manufacturing an electrochemical sensor comprising a substrate, and at least two layers to be printed on the substrate, the method comprising transporting a web of the substrate past first and second print stations, a drying station, positioned between the print stations, and a cooling station, located between the drying station and the second print station; printing a first layer on the substrate as it is transported past the first print station, drying the layer on the substrate in the drying station and cooling the printed substrate in the cooling station before printing a second layer on the substrate as it is transported past a second print station.

118. 发明公开

EP1806580A1 METHOD OF DETERMINING LEVEL OF SPECIFIED COMPONENT IN BLOOD SAMPLE AND APPARATUS FOR LEVEL DETERMINATION 有权
标题翻译： METHOD FOR A所列COMPONENT用于确定MIRROR确定反射镜IN的血液样品和装置
公开(公告)号：EP1806580A1
公开(公告)日：2007-07-11
申请号：EP05799319.8
申请日：2005-10-25
申请人： Arkray, Inc.
发明人： SUGIYAMA, Koji c/o ARKRAY Inc. , TAKAGI, Takeshi c/o ARKRAY Inc.
IPC分类号： G01N33/49 , G01N27/327 , G01N27/416 , G01N33/483
CPC分类号： G01N27/3271
摘要： The present invention relates to a method for measuring the concentration of a particular component in a blood sample containing blood cells based on a variable correlated with the concentration of the particular component. In the present invention, a concentration (S) in blood plasma obtained by removing blood cell components from the blood sample, a concentration (DI) in the blood sample computed by a differential method and a concentration (EP) in the blood sample computed by an equilibrium point method are expressed by a relational expression which is unrelated to the proportion of the blood cell components in the blood sample, and the concentration of the particular component is computed by using the relational expression.
摘要翻译：本发明涉及一种用于测量包含基于与所述特定成分的浓度相关联的变量的血细胞的血液样品中的特定成分的浓度的方法。在本发明中，在血浆中的浓度（S）通过从所述血液样品，通过差的方法和通过计算得到的血液样品中的浓度（EP）中计算出的血液样品中的浓度（DI）中除去血细胞成分获得在平衡点法是由关系表达式所有这些是无关的血液样品中的血球成分的比例，和特定成分的浓度是通过使用上述关系式计算的过表达。

119. 发明公开

EP1790861A1 Microfluidic system 审中-公开
标题翻译： Mikrofluidisches系统
公开(公告)号：EP1790861A1
公开(公告)日：2007-05-30
申请号：EP05111343.9
申请日：2005-11-25
申请人： Bonsens AB , Griss, Patrick , Samel, Björn
发明人： Stemme, Göran , Griss, Patrick , Samel, Björn , Neftel, Frédéric , Piveteau, Laurent-Dominique
IPC分类号： F15C5/00 , B01L3/00 , F04B19/00
CPC分类号： B01L3/50273 , B01L3/502738 , B01L3/502746 , B01L2300/0816 , B01L2300/0825 , B01L2300/0861 , B01L2300/0887 , B01L2400/0481 , B01L2400/0655 , B01L2400/0672 , F04B43/043 , F16K99/0001 , F16K99/0026 , F16K99/0036 , F16K99/004 , F16K99/0061 , F16K2099/008 , F16K2099/0084 , F16K2099/0086 , G01N27/3271 , G01N33/4905 , Y10T137/2191 , Y10T137/2196
摘要： Microfluidic system (1,2,10,11,16) comprising a first portion (3,4,24,25) and a second portion (5-7,17-19), said first portion (3,4,24,25) comprising a material which is able to change its volume when activated by an exciting factor, characterized by the fact that said first portion (3,4,24,25) and said second portion (5-7,17-19) define a zone (3-7,17-19) which, when said first portion (3,4,24,25) is not yet activated by said exciting factor, shows a first topography and which, after activation by said exciting factor, shows a second topography (9,14), said second topography (9,14) being adapted to contain a certain amount of fluid, said microfluidic system furthermore comprising a tight cover surface (20) situated above said first portion (3,4,24,25) and said second portion (5-7).
摘要翻译：包括第一部分（3,4,24,25）和第二部分（5-7,17-19）的微流体系统（1,2,10,11,16），所述第一部分（3,4,24,25） 25）包括当被激励因子激活时能够改变其体积的材料，其特征在于所述第一部分（3,4,24,25）和所述第二部分（5-7,17-19）限定当所述第一部分（3,4,24,25）尚未被所述激发因子激活时，所述区域（3-7,17-19）示出了第一形貌，并且在所述激发因子激活之后，显示第二形貌（9,14），所述第二形貌（9,14）适于容纳一定量的流体，所述微流体系统还包括位于所述第一部分（3,4,24）上方的紧密覆盖表面（20），25）和所述第二部分（5-7）。

120. 发明公开

EP1785494A1 Application of biosensor chips 有权转让
标题翻译： Anwendung von Biosensorchips
公开(公告)号：EP1785494A1
公开(公告)日：2007-05-16
申请号：EP06255550.3
申请日：2006-10-27
申请人： SEIKO EPSON CORPORATION
发明人： Tam, Simon, c/o Cambridge Research Laboratory
IPC分类号： C12Q1/68 , G01N27/414 , G06K19/077
CPC分类号： G01N27/3271
摘要： A method of sensing a property of each of a plurality of samples is disclosed. The method comprises disposing a sensor chip in each sample, the sensor chip being adapted to sense the property of a respective sample and comprising sensing electronics, a wireless communication device and an identifier especially RFID (120). Each sensor chip is then registered and sensed data is received from each of the registered sensor chips concurrently via the respective wireless communication device.
摘要翻译：公开了一种感测多个样本中的每一个的属性的方法。所述方法包括在每个样本中布置传感器芯片，所述传感器芯片适于感测相应样品的特性，并且包括感测电子设备，无线通信设备和识别器，特别是RFID（120）。然后通过相应的无线通信设备同时登记每个传感器芯片并从每个注册的传感器芯片接收感测数据。

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