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101. 发明公开

EP2429417A1 SURGICAL FASTENERS, APPLICATOR INSTRUMENTS, AND METHODS FOR DEPLOYING SURGICAL FASTENERS 有权
标题翻译：设备用于放置手术紧固元件
公开(公告)号：EP2429417A1
公开(公告)日：2012-03-21
申请号：EP10718801.3
申请日：2010-05-07
申请人： Ethicon, Inc
发明人： COHN, Simon , CARDINALE, Michael , FUCHS, Richard, P. , DANIEL, Matthew, David , JARRETT, Jeremy, David
IPC分类号： A61B17/068 , A61B17/128
CPC分类号： A61B17/0682 , A61B17/064 , A61B17/1285 , A61B2090/0807
摘要： A firing system for an applicator instrument adapted to dispense surgical fasteners includes a housing, an elongated shaft extending from the housing, a firing rod disposed within the elongated shaft, a firing rod release engageable with the firing rod for preventing distal movement of the firing rod during at least one stage of a firing cycle, a trigger mounted to the housing, and a firing spring having a first end connected with the firing rod and a second end adapted for being sequentially coupled and decoupled from the trigger during the firing cycle. The firing cycle includes an initial stage in which the trigger is open and decoupled from the energy storing element, and the firing spring is at least partially compressed, and a piloting stage during which the firing rod release is disengaged from the firing rod for enabling distal movement of the firing rod.

102. 发明授权

EP2086464B1 IMPLANTABLE REPAIR DEVICE 有权
标题翻译： IMPLANTIERBARE REPARATURVORRICHTUNG
公开(公告)号：EP2086464B1
公开(公告)日：2012-03-07
申请号：EP07854306.3
申请日：2007-10-23
申请人： Ethicon, Inc
发明人： ROUSSEAU, Robert A. , LINDH, David C. Sr. , JACOBS, John R. , KOYFMAN, Ilya S. , CHEN, Gaoyuan Gavin , HILL, Donald G.
IPC分类号： A61F2/00
CPC分类号： A61F2/02 , A61F2/0063 , A61F2002/0068 , A61F2210/0004
摘要： An implantable prosthesis for repairing or reinforcing a tissue or muscle wall defect including a first composite structure including at least one layer of a non-absorbable material, wherein the first composite structure has a central portion sized and shaped to cover at least a portion of the tissue or muscle wall defect, and has an outer periphery. The prosthesis further includes a second structure having a reinforced central region and an outer peripheral edge, a reinforcing element positioned between the first and second structures, and having an outer periphery and a stiffness greater than that of the first and second structures, and at least one pulling element coupled to the reinforced central region of the second structure. The second structure is coupled to the first structure substantially only at their respective peripheries.
摘要翻译：公开了一种用于修复或加强组织或肌肉壁缺陷的可植入假体，其包括包括至少一层不可吸收材料的第一复合结构。第一复合结构具有中心部分的尺寸和形状以覆盖组织或肌肉壁缺损的至少一部分，并具有外周。假体还包括具有加强的中心区域和外周边缘的第二结构，位于第一和第二结构之间的加强元件，并且具有大于第一和第二结构的外周边和刚度的至少一个牵引元件联接到第二结构的加强中心区域。第二结构基本上仅在它们各自的周边耦合到第一结构。

103. 发明公开

EP2413812A1 PACKAGED ANTIMICROBIAL MEDICAL DEVICE AND METHOD OF PREPARING SAME 有权转让
标题翻译：包装的抗微生物医疗装置及其制造方法
公开(公告)号：EP2413812A1
公开(公告)日：2012-02-08
申请号：EP10711810.1
申请日：2010-03-30
申请人： Ethicon, Inc
发明人： REYHAN, Mehmet , CERWIN, Robert
IPC分类号： A61B17/06
CPC分类号： A61B17/04 , A61B17/06114 , A61B17/06166 , A61B50/00 , A61B2050/3005 , A61L17/005
摘要： A method of making a packaged antimicrobial suture. The method includes the steps of providing a containment compartment molded from a polymeric resin comprising a polymeric material and an antimicrobial agent, positioning a suture within the containment compartment, the suture comprising one or more surfaces; covering the containment compartment having the suture in an outer package cover having an inner surface, and subjecting the outer package, the containment compartment and the suture to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the containment compartment to the suture, while retaining an effective amount of the antimicrobial agent on the containment compartment, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment. A packaged antimicrobial suture is also provided.

104. 发明公开

EP2391393A2 PCL/PGA HEMOSTATIC FOAMS 审中-公开
标题翻译：止血PCL / PGA泡沫材料
公开(公告)号：EP2391393A2
公开(公告)日：2011-12-07
申请号：EP10702388.9
申请日：2010-01-29
申请人： Ethicon, Inc
发明人： YANG, Chunlin , MATALENAS, Thomas , JOHN, Thoppil, Mathew
IPC分类号： A61L15/26 , A61L15/32 , A61L15/42
CPC分类号： A61K38/39 , A61L24/0036 , A61L24/046 , A61L24/10 , A61L2400/04 , C07K14/001 , C07K14/78 , G01N33/86 , G01N2800/224 , Y10T428/24496 , C08L67/04
摘要： The present invention relates to a collagen-related polypeptide (CRP) having hydrophobic amino acid groups at the N- and C-termini capable of non-covalent self-assembly into collagen mimetic triple helices and fibrils thereof and the synthesis, methods of use and compositions thereof. The present invention also relates to novel hemostatic foam substrates, a method of manufacturing the foam substrates, and a method of stimulating hemostasis in a mammal using such foam substrates.

105. 发明公开

EP2387437A1 OPTIMIZING THE STIMULUS CURRENT IN A SURFACE BASED STIMULATION DEVICE 审中-公开
标题翻译：优化技术在刺激设备兴奋剂流量在曲面
公开(公告)号：EP2387437A1
公开(公告)日：2011-11-23
申请号：EP09760677.6
申请日：2009-11-20
申请人： Ethicon, Inc
发明人： DIUBALDI, Anthony , WAHLGREN, Stephen
IPC分类号： A61N1/08 , A61N1/36
CPC分类号： A61N1/36014
摘要： A method and associated stimulation device for ensuring firing of an action potential in an intended physiological target activated by a stimulus pulse generated by an electrode of a non-invasive surface based stimulation device irrespective of skin-to-electrode impedance by: (i) increasing internal impedance of the stimulation device so as to widen a Chronaxie time period thereby ensuring firing of the action potential of the intended physiological target irrespective of the skin-to-electrode impedance; and/or (ii) generating a stimulation waveform that optimizes a non-zero average current (e.g., non-zero slope of the envelope of the stimulation waveform) during preferably substantially the entire current decay of the stimulus pulse.

106. 发明公开

EP2381855A1 SURGICAL NEEDLE SWAGE TOOL 有权
标题翻译：手术针SWAY工具
公开(公告)号：EP2381855A1
公开(公告)日：2011-11-02
申请号：EP09795604.9
申请日：2009-12-04
申请人： Ethicon, Inc
发明人： STAMETZ, Jerry , PRICE, John , REYNOLDS, Eugene , BARSCH, Kenneth
IPC分类号： A61B17/06
CPC分类号： A61B17/06004 , A61B2017/00526 , A61B2017/06028 , Y10T29/49925
摘要： in a method of attaching a suture (84) to a needle barrel (82), a first compression stroke compresses the radially-defined top (86) of the barrel (82) against a suture (84) in the bore (96) of the barrel (82) while restraining the bottom (88) and sides (90, 92) of the barrel (82) against deformation A second compression stroke compresses the bottom (88) of the barrel (82) against the suture (84) while restraining the sides (90 92) against deformation In another method, the top (86) and bottom (88) are compressed concurrently while the sides (90, 92) are restrained against deformation An apparatus for attaching a suture (84) to a needle barrel (82) includes two die sets (22, 48) each including a die (24, 52) with a groove (40, 70) therein In one die set (22), the groove (40) protects the bottom (88) and sides (90, 92) of the barrel (82) from deformation while the top (86) is compressed In the other die set (48), the groove (70) protects the sides (90, 92) of the barrel (82) from deformation while the bottom (88) is compressed.
摘要翻译：在将缝合线84附接到针筒82的方法中，第一压缩冲程压缩针筒82的径向限定的顶部86抵靠孔96中的缝合线84。同时限制筒体82的底部88和侧部90,92以防止变形。第二压缩冲程压缩筒体82的底部88抵靠缝合线84，抑制侧部（90,92）的变形在另一种方法中，顶部（86）和底部（88）同时被压缩，同时侧部（90,92）被限制而不变形。用于将缝合线（84）（82）包括两个模组（22,48），每个模组包括其中具有沟槽（40,70）的模具（24,52）。在一个模具组（22）中，沟槽（40）保护底部（88）（82）的侧面（90,92）在顶部（86）被压缩时发生变形。在另一个模具组（48）中，凹槽（70）保护针筒（82）的侧部（90,92））从变形而底部（88）被压缩。

107. 发明授权

EP1795210B1 Wound dressings comprising oxidized cellulose and human recombinant collagen 有权
标题翻译：一种伤口敷料，包括氧化纤维素和人重组胶原
公开(公告)号：EP1795210B1
公开(公告)日：2011-11-02
申请号：EP06256271.5
申请日：2006-12-08
申请人： ETHICON, INC.
发明人： Boyle, Clare , Silcock, Derek Walter , Cullen, Breda Mary
IPC分类号： A61L15/22 , A61L15/42 , A61L15/28 , A61L15/32
CPC分类号： A61L15/325 , A61L15/225 , A61L15/28 , A61L15/425 , C08L89/06 , C08L1/04

108. 发明公开

EP2366018A1 METHOD OF MAKING CONDITIONED MEDIA FROM KIDNEY DERIVED CELLS 审中-公开
标题翻译：用于生产条件培养基从肾脏来源于细胞
公开(公告)号：EP2366018A1
公开(公告)日：2011-09-21
申请号：EP09775031.9
申请日：2009-12-01
申请人： Ethicon, Inc
发明人： COLTER, David, C. , KAZANECKI, Christian , KRAMER, Brian, C. , DONNERS, Jackie, J.
IPC分类号： C12N5/00
CPC分类号： C12N5/0686 , C12N2533/40
摘要： Methods of making conditioned media by culturing cells on nonwoven substrates are disclosed. More specifically, methods of making conditioned media by culturing mammalian kidney-derived cells on nonwoven substrates are disclosed.

109. 发明公开

EP2358780A2 ISOCYANATE TERMINATED MACROMER AND FORMULATION THEREOF FOR USE AS AN INTERNAL ADHESIVE OR SEALANT 有权
标题翻译：异氰酸酯单体及其制剂FOR USE内部粘合剂或密封胶
公开(公告)号：EP2358780A2
公开(公告)日：2011-08-24
申请号：EP09775057.4
申请日：2009-12-16
申请人： Ethicon, Inc
发明人： KHARTI, Chetan, Anirudh , FITZ, Benjamin, D. , ZAVATSKY, Joseph
IPC分类号： C08G18/77
CPC分类号： C08G18/771 , A61L24/046 , A61L2400/06 , C08G18/10 , C08G18/42 , C08G18/4238 , C08L75/04
摘要： A novel macromer or mixture thereof is described herein, comprising isocyanatophenyl ether terminal moieties and at least two residues of a water-soluble polymer having a molecular weight ranging from 80 to 10,000 adjacent to the ether group of the isocyanatophenyl ether terminal isocyanate moieties, thereby forming at least two ether linkages in the macromer or mixture thereof. A method for making a polyisocyanate macromer is also described herein.

110. 发明公开

EP2349407A2 DISPOSABLE INFUSION DEVICE WITH OCCLUSION DETECTOR 有权转让
标题翻译：与障碍物检测一次性输液设备
公开(公告)号：EP2349407A2
公开(公告)日：2011-08-03
申请号：EP09823967.6
申请日：2009-06-26
申请人： Calibra Medical, Inc.
发明人： CARTER, Brett, J.
IPC分类号： A61M5/168 , A61M5/162
CPC分类号： A61M5/1424 , A61M5/14216 , A61M5/14248 , A61M5/16854 , A61M2005/1402 , A61M2005/1585 , A61M2005/16863 , A61M2205/273
摘要： A disposable wearable infusion device comprises a reservoir that holds a liquid medicament and a cannula having a distal end that delivers the liquid medicament to a patient. The device further comprises a pump that displaces a volume of the liquid medicament along a path to the cannula when actuated and a lock-out that precludes actuation of the pump when an occlusion occurs within the path to the distal end of the cannula.

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