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    • 91. 发明公开
    • MULTI-STAGED FILTRATION SYSTEM FOR BLOOD FLUID REMOVAL
    • N ES N N N N N N N N N N N N N N N N N N
    • EP2800592A1
    • 2014-11-12
    • EP13733819.0
    • 2013-01-04
    • Medtronic Inc.
    • COLLIER, Kenneth, J.PUDIL, Bryant, J.GERBER, Martin, T.
    • A61M1/34A61M1/16
    • A61M1/3472A61M1/14A61M1/16A61M1/1633A61M1/34A61M1/3475A61M1/3479A61M1/3482A61M1/3486A61M2205/75B01D15/08B01D61/145B01D61/243B01D61/28B01D63/00B01D63/043B01D63/08B01D2313/40B01D2317/02B01D2319/06
    • A device includes (i) a housing defining an interior, wherein the interior has a blood compartment, a plasma compartment, and a fluid compartment; (ii) a first filter disposed in the interior of the housing, and (iii) a second filter disposed in the interior of the housing. The first filter separates at least a portion of the blood compartment from at least a portion of the plasma compartment. The first filter is configured to allow plasma components, but not cell components, of blood to pass through the first filter from the blood compartment to the plasma compartment. The second filter separates at least a portion of the plasma compartment from at least a portion of the fluid compartment. The second filter is configured to allow fluid and small molecules, but not larger components, to pass through the second filter from the plasma compartment to the fluid compartment. The device may include a sorbent in the plasma compartment to remove or reduce the concentration of selected components of the plasma. In embodiments, a system including the device includes a sorbent with which the plasma may be contacted.
    • 一种装置包括(i)限定内部的壳体,其中内部具有血液隔室,等离子体隔室和流体隔室; (ii)设置在壳体内部的第一过滤器,和(iii)设置在壳体内部的第二过滤器。 第一过滤器将血液隔室的至少一部分与等离子体隔室的至少一部分分开。 第一过滤器被配置为允许血液的血浆成分(而不是细胞组分)从血液隔室通过第一过滤器到等离子体室。 第二过滤器将至少一部分等离子体隔室与流体室的至少一部分分离。 第二过滤器被配置为允许流体和小分子但不是较大的组分通过第二过滤器从等离子室到流体室。 该装置可以包括在等离子体室中的吸附剂以去除或降低等离子体的选定组分的浓度。 在实施方案中,包括该装置的系统包括可与等离子体接触的吸附剂。