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    • 95. 发明公开
    • Liquid drug degasing devise and ambulatory infusion system including a degasing device
    • 一种用于液体脱气药物和移动式输注系统,包括脱气装置
    • EP2371408A2
    • 2011-10-05
    • EP10009698.1
    • 2010-09-16
    • Roche Diagnostics GmbHF.Hoffmann-La Roche AG
    • Dogwiler, JörgHuwiler, ChristophMichel, Philipp
    • A61M5/36A61M5/38
    • A61M5/385A61M5/14244A61M5/36A61M5/38A61M2205/75A61M2205/7527A61M2205/7536B01D19/00B01D19/0031B01D53/22B01D63/08B01D2313/365B01D2313/90B01D2325/36B01D2325/38
    • Disclosed is a degassing device (100) for removing gas bubbles from a liquid drug stream, the degassing device including:
      a) an inlet chamber (102), with an inlet opening (104), an outlet chamber (106) with an outlet opening (108), and a degassing opening (114), and
      b) a hydrophilic membrane (110) and a hydrophobic membrane (112),

      wherein
      • the hydrophilic membrane (110) fluidically couples the inlet chamber (102) with the outlet chamber (106), thus enabling a transfer of liquid from the inlet chamber (102) to the outlet chamber (106) through the hydrophilic membrane (110),
      • the hydrophobic membrane (112) fluidically couples the inlet chamber (102) wit the degassing opening (114), thus enabling a transfer of gas from the inlet chamber (102) to the degassing opening (114) through the hydrophobic membrane 112, and
      • the hydrophilic membrane (110) and the hydrophobic membrane (112) are joint along a joint (116) to establish a joined membrane (110 112) such that a contact line of a liquid-gas phase separation on the joined membrane (110, 112) does not coincide with the joint (116) independent of an orientation of the degassing device (100) with respect to gravity.

      Disclosed is further an ambulatory infusion system comprising such a degassing device.
    • 公开了一种用于从液体药物流中除去气泡,包括脱气装置脱气装置(100):在出口开口与a)至入口室(102),其具有入口开口(104)到出口腔室(106) (108),和一个除气开口(114),以及b)亲水性膜(110)和一个疏水性膜(112),worin€¢亲水膜(110)流体地耦合所述入口室(102)与所述出口室 (106)从而使液体从入口室(102)通过亲水性膜(110)的出口室(106)的转印€¢疏水膜(112)耦合流体的入口室(102)机智的 脱气开口(114),从而使得能够从所述入口室(102)到脱气开口(114)通过所述疏水膜112和€¢亲水膜(110)和所述疏水膜(112)是关节气体的转印 沿着接头(116),以建立一个接合膜(110 112)搜索做的接触线 在接合膜的液体 - 气体相分离的(110,112)不与独立于脱气装置(100)的相对于重力的定向的所述接合部(116)重合。 公开的是继移动式输注系统,包括寻求脱气装置。