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1. 发明公开

EP4227294A1 CURABLE COMPOUND PRODUCT 审中-实审
公开(公告)号：EP4227294A1
公开(公告)日：2023-08-16
申请号：EP21877623.5
申请日：2021-10-05
申请人： Daicel Corporation
发明人： OKANO, Yoshimichi , NAKATANI, Kouji
IPC分类号： C07D207/452 , C08F38/00 , C08G65/333 , C08G65/48 , C09D201/00 , C09J201/00 , B32B7/027
摘要： Provided is a curable compound product having excellent storage stability and moldability and by which a cured product having ultra-high heat resistance can be formed. The curable compound product according to the present disclosure has the following characteristics (a) to (g): (a) A number average molecular weight (calibrated with polystyrene standard) is from 1000 to 15000. (b) A proportion of a structure derived from an aromatic ring in a total amount of the curable compound product is 50 wt.% or greater. (c) Solvent solubility at 23°C is 1 g/100 g or greater. (d) The glass transition temperature is from 80 to 230°C. (e) A viscosity (η 0 ) of a 20 wt.% NMP solution obtained by subjecting the curable compound product to a reduced-pressure drying process and then dissolving the reduced-pressure-dried curable compound product in NMP, and a viscosity (η 10 ) of the 20 wt.% NMP solution after being left to stand for 10 days in a desiccator maintained at 23°C satisfy the Equation (E): η 10 /η 0

2. 发明授权

EP2716625B1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF 有权
公开(公告)号：EP2716625B1
公开(公告)日：2020-11-11
申请号：EP12792317.5
申请日：2012-05-31
申请人： DIC Corporation
发明人： SCHADT Martin , NOSE Sayaka , IWAKUBO Masayuki , HAYASHI Masanao , NAGASHIMA Yutaka , NISHIYAMA Isa , TAKATSU Haruyoshi
IPC分类号： C07C69/732 , C07C69/92 , C07D207/452 , C07D257/08 , C08F20/40 , C08F22/40 , C09K19/04 , C09K19/56 , G02F1/1337

3. 发明授权

EP3455206B1 CHEMICAL CONJUGATES OF EVANS BLUE DERIVATIVES AND THEIR USE AS RADIOTHERAPY AND IMAGING AGENTS 有权
公开(公告)号：EP3455206B1
公开(公告)日：2020-11-04
申请号：EP17796666.0
申请日：2017-05-09
申请人： The U.S.A. as represented by the Secretary, Department of Health and Human Services
发明人： CHEN, Xiaoyuan , WEISS, Orit Jacobson
IPC分类号： C07D207/444 , C07D207/452 , A61K51/04 , A61K51/08 , A61P35/00

4. 发明公开

EP3590922A1 CYTOTOXIC AND ANTI-MITOTIC COMPOUNDS, AND METHODS OF USING THE SAME 审中-实审转让
公开(公告)号：EP3590922A1
公开(公告)日：2020-01-08
申请号：EP19174765.8
申请日：2014-03-14
申请人： Zymeworks Inc.
发明人： WINTERS, Geoffrey C. , MANDEL, Alexander Laurence , RICH, James R , HEDBERG, Bradley John , HSIEH, Tom Han Hsiao , BOURQUE, Elyse Marie Josée , BABCOOK, John
IPC分类号： C07D207/08 , C07D207/452 , C07D211/34 , C07D211/60 , C07D213/56 , C07D213/71 , C07D333/34 , C07C311/51 , C07C323/12 , C07C323/67 , C07C327/06 , C07C381/08 , A61K38/05 , A61K38/06 , A61P35/00
摘要： Compounds having cytotoxic and/or anti-mitotic activity are disclosed. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed. Also disclosed are compositions having the structure: (T)-(L)-(D), wherein (T) is a targeting moiety, (L) is an optional linker, and (D) is a compound having cytotoxic and/or anti-mitotic activity.

5. 发明授权

EP3362434B1 CROSS-LINKABLE CHARGE TRANSPORT MATERIALS 有权
公开(公告)号：EP3362434B1
公开(公告)日：2019-08-28
申请号：EP16784247.5
申请日：2016-10-13
申请人： Lomox Limited
发明人： ALDRED, Matthew P. , JUDD, Luke WIlliam , FODEN, Clare
IPC分类号： C07D207/452 , C07C217/80 , H01L51/50

7. 发明授权

EP2509638B1 IODINE RADIOLABELLING METHOD 有权
标题翻译：放射性药物MARKIERUNGSVERFAHREN MIT JOD
公开(公告)号：EP2509638B1
公开(公告)日：2017-04-19
申请号：EP10788337.3
申请日：2010-12-10
申请人： GE Healthcare Limited
发明人： AVORY, Michelle
IPC分类号： A61K51/08 , C07K1/13 , C07C247/16 , C07D249/06 , C07D261/08 , C07D207/452 , C07B59/00 , C07C291/06 , C07D231/12 , C07K5/09
CPC分类号： A61K51/08 , C07B59/002 , C07B2200/05 , C07C247/16 , C07C291/06 , C07D231/12 , C07D249/06 , C07D261/08 , C07K1/13 , C07K5/0817 , G01N2800/52

8. 发明公开

EP3131898A1 FLUOROALKYLFLUORENE DERIVATIVES 有权
标题翻译：氟代烷基芴衍生物
公开(公告)号：EP3131898A1
公开(公告)日：2017-02-22
申请号：EP15727031.5
申请日：2015-04-17
申请人： Lomox Limited
发明人： KOCH, Gene Carl , JUDD, Luke William , ALDRED, Matthew Phillip
IPC分类号： C07D417/14 , C07C65/26 , C07C35/21 , C07C69/92 , C07C43/225 , C07D207/452 , C07D285/14 , H01L51/00
摘要： Compounds according to formula D-SÂ¹-A-BÂ¹, where: A represents -Ar1-(FL-Ar2)n-; Ar1 and Ar2 each represent a bond or an aromatic or heteroaromatic diradical, or two aromatic or heteroaromatic diradicals mutually connected by a single bond, or a FL moiety, or two FL moieties mutually connected by a single bond; n is an integer from 1-8. FL represents a 2,7- disubstituted 9,9-fluoroalkyl fluorene diradical according to the formula as shown where R preferably represents an alkyl group; S1 and S2 are flexible linker groups, preferably octyloxy groups. D represents a crosslinkable group, and may be a vinyl ether, maleimide, maleate, or fumarate group. B1 is a crosslinkable group or a hydrogen atom. The fluoroalkylfluorene derivatives may be liquid crystalline materials. Network polymers may be formed by exposure of the crosslinkable groups to radiation, preferably ultraviolet radiation. Also claimed is a device comprising a plurality of charge transport layers and/or emissive layers that contain compounds as defined above. Preferably the device is an OLED device. Preferably the OLED device comprises a light emitting layer that comprises a compound as defined above comprising a uniformly aligned liquid crystalline structure.
摘要翻译：根据式D-S-A-B-1的化合物，其中：A表示-Ar1-（FL-Ar2）n-; Ar 1和Ar 2各自表示键或芳族或杂芳族二价基团，或通过单键或FL部分或通过单键相互连接的两个FL部分相互连接的两个芳族或杂芳族二价基团; n是1-8的整数。 FL表示根据下式表示的2,7-二取代的9,9-氟烷基芴双基，其中R优选表示烷基; S1和S2是柔性连接基团，优选辛氧基。 D表示可交联基团，并且可以是乙烯基醚，马来酰亚胺，马来酸酯或富马酸酯基团。 B1是可交联基团或氢原子。氟代烷基芴衍生物可以是液晶材料。网状聚合物可通过将可交联基团暴露于辐射，优选紫外辐射而形成。还要求保护的是包含含有如上定义的化合物的多个电荷传输层和/或发射层的器件。优选地，该器件是OLED器件。优选地，OLED器件包括发光层，该发光层包含如上定义的包含均匀排列的液晶结构的化合物。

9. 发明授权

EP2806899B1 INTEGRIN ANTAGONIST CONJUGATES FOR TARGETED DELIVERY TO CELLS EXPRESSING ALPHA-V-BETA-3 有权
标题翻译：整合素拮抗剂缀合物用于靶向递送至表达α-V-β-3的细胞
公开(公告)号：EP2806899B1
公开(公告)日：2016-10-19
申请号：EP13701748.9
申请日：2013-01-22
申请人： F.Hoffmann-La Roche AG
发明人： GOODNOW JR., Robert Alan , HAMILTON, Matthew Michael , KOWALCZYK, Agnieszka , SIDDURI, Achyutharao
IPC分类号： A61K47/48 , A61P35/00 , A61P29/00 , C07D239/14 , C07D417/12 , C07D207/452 , C07D277/593
CPC分类号： C07D277/593 , A61K47/48061 , A61K47/48092 , A61K47/48215 , A61K47/545 , A61K47/549 , A61K47/60 , C07C237/52 , C07C327/32 , C07D207/452 , C07D239/14 , C07D417/12

10. 发明授权

EP1812031B1 COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES 有权转让
标题翻译：组合物和方法进行修饰生物分子
公开(公告)号：EP1812031B1
公开(公告)日：2015-06-24
申请号：EP05823231.5
申请日：2005-10-31
申请人： The Regents of the University of California
发明人： BERTOZZI, Carolyn, R. , AGARD, Nicholas, J. , PRESCHER, Jennifer, A. , BASKIN, Jeremy, Michael
IPC分类号： A61K47/48 , C07C45/51 , C07C49/457 , C07C59/72 , C07C63/66 , C07C63/74 , C07C69/708 , C07C69/76 , C07D207/416 , C07D207/452 , C07D249/16 , C07D495/04 , G01N33/531 , G01N33/58 , G01N33/68
CPC分类号： G01N33/6842 , A61K47/54 , A61K47/555 , C07C45/511 , C07C49/457 , C07C59/72 , C07C63/66 , C07C63/74 , C07C69/708 , C07C69/76 , C07C2601/18 , C07D207/416 , C07D207/452 , C07D249/16 , C07D495/04 , G01N33/531 , G01N33/58 , G01N33/6803

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