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    • 1. 发明公开
    • REACTION APPARATUS, AND REACTION METHOD
    • REAKTIONSAPPARAT UND REAKTIONSVERFAHREN
    • EP2065354A1
    • 2009-06-03
    • EP07807353.3
    • 2007-09-14
    • Banyu Pharmaceutical Co., Ltd.
    • YONEDA, NoriyukiODA, YuichiNAKANISHI, Yasuo
    • C07B61/00B01J19/24C07C67/343C07C69/716
    • C07D487/04B01J19/243B01J2219/00063C07C67/343C07C69/716
    • The present invention is directed at obtaining a high yield of a target substance and simultaneously securing high productivity.
      A reaction apparatus 10 has: a main flow channel 12 having an inner diameter of 3 mm, in which a raw material M 1 flows; an introduction flow channel 14 in which a raw material M 2 that causes a chemical reaction with the raw material M 1 flows; and five branch introduction flow channels 16a to 16e which are branched from the introduction flow channel 14 and introduce the raw material M 2 to the main flow channel 12, at predetermined introduction points 12o to 12s in the main flow channel 12. Here, in the main flow channel 12, the flow channel lengths of the flow channels 12b to 12d between adjacent introduction points 12p to 12s are not longer than those of the flow channels 12a to 12c between the next previous adjacent introduction points 12o to 12r in a flow direction of the raw material M 1 . At least one length of the flow channels 12b to 12d between the adjacent introduction points 12p to 12s is shorter than lengths of the flow channels 12a to 12c between previous adjacent introduction points 12o to 12r in the flow direction of the raw material M 1 .
    • 本发明涉及获得高产率的目标物质并同时确保高生产率。 反应装置10具有:原料M 1流入的内径为3mm的主流路12; 导入与原料M 1发生化学反应的原料M 2的导入流路14; 以及从导入流路14分支并将原料M 2引导到主流路12的5个分支导入流路16a〜16e,在主流路12的规定的导入点12o〜12s。这里, 主流路12中,相邻导入点12p〜12s之间的流路12b〜12d的流路长度不比前一相邻导入点12o〜12r之间的流路12a〜12c的流路长度在流动方向 原料M 1。 相邻导入点12p〜12s之间的流路12b〜12d的至少一个长度比原料M 1的流动方向上的前一相邻导入点12o〜12r之间的流路12a〜12c的长度短。