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    • 6. 发明申请
    • METHOD AND DEVICE FOR SHAPING STRUCTURAL PARTS
    • 方法和设备STRUKTUBAUTEILEN深成形
    • WO02010332A1
    • 2002-02-07
    • PCT/DE2001/002601
    • 2001-07-17
    • B64F5/00B21D11/08B21D31/06B21D53/92B24C1/04B24C1/10C21D7/06C12D7/06B21B31/06
    • B24C1/04B21D11/085B24C1/10C21D7/06Y10T29/479
    • The invention relates to a method for shaping structural parts, in particular, those for use in aviation and space travel. The structural parts comprise a plate-shaped base body and ribs. Said ribs are longitudinally extended, are approximately parallel to one another, are joined to the base body while forming one piece, and protrude from the base body in orthogonal manner. The part is shaped by particles of an abrasive, which strike the surface areas of the structural part at a high velocity whereby effecting a plastic material shaping. The aim of the invention is to realize a method that can be carried out in a simple and cost-effective manner with which diverse uniaxial and multiaxial part geometries can be attained. To this end, the invention provides that opposite surface areas of the ribs, said surface areas being located on opposite longitudinal sides of each rib, are simultaneously subjected to the action of particles of the abrasive.
    • 公开了一种用于成形的结构部件,尤其是用于这样的在航空航天工业中使用的方法。 结构构件具有板形的基体和大致垂直延伸的一体地连接,细长的并且大致相互平行,与所述基体的肋。 该变换是由入射在所述结构部件的表面区域高的速度和产生的塑料材料变形的爆炸剂的组分颗粒进行。 为了获得一种简单且廉价地进行方法,其可以实现宽范围的单轴和多轴部件几何形状的,所以建议在每种情况下布置在相对的纵向侧的肋,翅片的彼此相对的表面区域被同时与爆炸剂的颗粒施加。
    • 9. 发明公开
    • Purification of pertussis Haemagglutinins
    • PERTUSSIS HAEMAGGLUTININS的纯化
    • EP0003916A3
    • 1979-10-03
    • EP79300312
    • 1979-03-01
    • Secretary of State for Social Services in Her Britannic Majesty's Government of the United Kingdom of Great Britain and
    • Irons, Laurence IanMaclennan, Alastair Patterson
    • C07G07/00C12D13/06A61K39/06
    • C07K14/235Y10S524/90Y10S530/825
    • The Leukocytosis Promoting Factor (LPF) of Bordetella haemagglutinin (HG) is separated from crude cell supernatant or partially purified protein by affinity chromatography on a column material consisting of an insoluble polymeric support to which is bound a sialoprotein (containing sialic acid) or other substance rich in sialic acid. The sialoprotein was preferably a plasma sialoprotein such as haptoglobin or ceruloplasmin or a salivary mucin, and the polymeric support was preferably an agarose gel, though other conventional supports could be used. By this process, on treatment of an ammonium sulphate precipitated extract, the haemagglutinating activity may be increased 300-600 fold over the extract and 10.000 times over the crude centrifuged cell supernatant. Alternatively a fraction substantially free from LPF-HG may be collected. Pertussis LPF-HG is reported to have various useful clinical properties, in particular adjuvant effect on antigenicity and the abilities to induce leukocytosis and sensitivity to histamine. By the process of the present invention LPF-HG may be produced cheaply and in large quantities or removed from other cell extracts.
    • 通过亲和层析在由不结合的聚合物载体组成的柱材料上与粗细胞上清液或部分纯化的蛋白质从粗细胞上清液或部分纯化的蛋白质分离出白血病血细胞凝集素(HG)的白细胞增多促进因子(LPF),其结合唾液酸蛋白(含糖唾液酸)或其他 物质丰富唾液酸。 唾液酸蛋白质优选为血浆唾液酸蛋白,例如触珠蛋白或血浆铜蓝蛋白,或输送粘蛋白,聚合物载体优选为琼脂糖凝胶,尽管可以使用其它常规载体。 通过该方法,在硫酸铵沉淀提取物的处理中,血液凝聚活性比提取物提高300-600倍,粗离心细胞上清液增加10,000倍。 或者,可以收集基本上不含LPF-HG的级分。 据报道百日咳杆菌LPF-HG具有各种有用的临床特征,特别是对抗原性的辅助作用和诱导白细胞增多和对组胺敏感的能力。 通过本发明的方法,LPF-HG可以廉价且大量生产,或从其它细胞提取物中除去。