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    • 7. 发明申请
    • ASPIRATING AND DISPENSING SMALL VOLUMES OF LIQUIDS
    • 吸引和分配液体的小容量
    • US20090093065A1
    • 2009-04-09
    • US12207266
    • 2008-09-09
    • Zhong DingDave HeavnerRaymond JakubowiczRobert Seth Jones
    • Zhong DingDave HeavnerRaymond JakubowiczRobert Seth Jones
    • G01N1/28G01N1/10G01N35/10G01N33/00
    • B01L3/0268B01L3/022B01L2200/0605B01L2200/0684B01L2200/146B01L2200/147B01L2300/0838B01L2300/14B01L2300/1822B01L2300/185B01L2300/1855B01L2300/1888B01L2400/0442B01L2400/0487G01N35/1016G01N2035/1039Y10T436/2575
    • A metering device for aspirating and dispensing a liquid includes a housing; a pumping medium, preferably a gas containing chamber contained within the housing; a channel having a proximate end in fluid communication with the chamber and a distal end in fluid communication with an external environment; a heat or cold source providing a source of heat or cold to the gas containing chamber; and a temperature sensor for measuring the temperature inside the chamber. In a preferred embodiment, the device further includes a pressure sensor for measuring gas pressure inside the chamber, or multiple chambers. A method for aspirating and dispensing a liquid includes: providing a metering device for aspirating and dispensing a liquid that includes a housing; a gas containing chamber contained within the housing, the chamber; a channel having a proximate end in fluid communication with the chamber and a distal end in fluid communication with an external environment; a heat or cold source providing a source of heat or cold to the gas containing chamber; and a temperature sensor for measuring the temperature inside the chamber; providing a source of liquid to be aspirated; bringing the distal end of the channel into contact with the liquid; cooling the gas containing chamber with the heat or cold source to aspirate a first volume of liquid into the device; and heating the gas containing chamber to dispense a second volume of liquid out of the device. In a preferred embodiment, the metering device is a used in a diagnostic analyzer for determining the presence of one or more analytes in a sample.
    • 用于吸入和分配液体的计量装置包括壳体; 抽吸介质,优选地包含在壳体内的气体容纳室; 具有与所述室流体连通的近端的通道和与外部环境流体连通的远端; 为气体容纳室提供热源或冷源的热源或冷源; 以及用于测量室内温度的温度传感器。 在优选实施例中,该装置还包括用于测量腔室内的气体压力或多个腔室的压力传感器。 用于抽吸和分配液体的方法包括:提供用于抽吸和分配包括壳体的液体的计量装置; 容纳在所述壳体内的气体容纳室,所述室; 具有与所述室流体连通的近端的通道和与外部环境流体连通的远端; 为气体容纳室提供热源或冷源的热源或冷源; 以及用于测量室内温度的温度传感器; 提供要吸入的液体来源; 使通道的远端与液体接触; 用热或冷源冷却含气室,以将第一体积的液体吸入装置; 并加热含气室以将第二体积的液体分配出设备。 在优选实施例中,计量装置用于诊断分析器中,用于确定样品中一种或多种分析物的存在。