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1. 发明专利

JP2007117760A Slidable vascular filter 有权
标题翻译：可滑动血管过滤器
公开(公告)号：JP2007117760A
公开(公告)日：2007-05-17
申请号：JP2006352961
申请日：2006-12-27
申请人： Ev3 Inc , イーブイ3 インコーポレイテッド
发明人： KUSLEIKA RICHARD S , FINANDER BRIAN V
IPC分类号： A61B17/00
摘要： PROBLEM TO BE SOLVED: To provide a collapsible medical device which can easily be deployed and retracted during a minimally invasive medical procedure.
SOLUTION: The medical device has a distal end and a stop spaced proximally of the distal end. A proximal length of a mandrel extends proximally of the stop, and a distal length of the mandrel extends distally of the stop. An operation member has a radially expandable body, and has a proximal slider and a distal slider. The proximal slider and the distal slider are slidable along the mandrel independently of one another so that a different configurations of the operation member can be effected by the variation of the distance between the proximal slider and the distal slider. By urging the mandrel distally, the operation member is urged to a treatment site. Thus, the stop exerts a distal biasing force on the distal slider, acts against a restorage force of the operation member to axially elongate the operation member, and reduces the friction between the operation member and the wall wall of the vessel.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供一种在微创医疗过程中可以容易地部署和缩回的可折叠医疗装置。解决方案：医疗装置具有远端和远端近端间隔开的止动件。心轴的近端长度在止动件的近侧延伸，并且心轴的远端长度延伸到止动件的远侧。操作构件具有径向可扩张体，并且具有近端滑块和远侧滑块。近侧滑块和远侧滑块可以彼此独立地沿着心轴滑动，使得操作构件的不同构造可以通过近侧滑块和远侧滑块之间的距离的变化来实现。通过向远侧推动心轴，操作构件被推动到治疗部位。因此，止动件在远侧滑块上施加远端偏压力，抵抗操作构件的恢复力以使操作构件轴向伸长，并且减小操作构件与容器壁壁之间的摩擦力。版权所有（C）2007，JPO＆INPIT

2. 发明专利

JP2004267796A Medical device 有权
标题翻译：医疗装置
公开(公告)号：JP2004267796A
公开(公告)日：2004-09-30
申请号：JP2004164325
申请日：2004-06-02
申请人： Ev3 Inc , イーブイ3 インコーポレイティド
发明人： MAZZOCCHI RUDY , CLAUDE TIMOTHY , SEGERMARK JAMES
IPC分类号： A61B17/00 , A61B17/12 , A61B17/22 , A61B17/221 , A61F2/01 , A61M29/00
CPC分类号： A61F2/013 , A61B17/12022 , A61B17/12099 , A61B17/12109 , A61B17/12136 , A61B17/12172 , A61B17/12177 , A61B17/221 , A61B2017/00526 , A61F2/01 , A61F2002/011 , A61F2002/016 , A61F2230/0006 , A61F2230/0067 , A61F2230/0069 , A61F2230/0078 , A61F2230/008 , B21F45/008
摘要： PROBLEM TO BE SOLVED: To provide a highly reliable embolus device easily and accurately arrangeable in a vesssel. SOLUTION: This system applies an intravascular treatment to a treating part in a lumen defined by a wall of the vascular in a vasucular system of a patient, and has a guide wire, a filter element attached to a distal end area of the guide wire, that is, the filter element expandable to an expanding state when not restricting the filter element from a contraction state when restricting the filter element, a filter element and a balloon catheter suitable for applying a blood vessel forming treatment, that is, the balloon catheter having a dimension-set lumen so as to slidingly house the guide wire. The guide wire is positioned so as to cross a stenosis part in the vessel in use. A filter is expanded, and a balloon is expanded in the stenosis part. Before removing the expandable filter from the vessel, an embolus material is generated, and is captured by the filter element. COPYRIGHT: (C)2004,JPO&NCIPI
摘要翻译：要解决的问题：提供容易且准确地布置在容器中的高度可靠的栓塞装置。解决方案：该系统对患者的血管系统中由血管壁限定的内腔中的治疗部位进行血管内治疗，并且具有引导线，连接到患者的远端区域的过滤元件导丝，即，当限制过滤元件时不限制过滤元件从收缩状态扩展到膨胀状态的过滤元件，适用于施加血管形成处理的过滤元件和气囊导管，即，气球导管具有尺寸设定的内腔以滑动地容纳导丝。引导线定位成在使用中穿过容器中的狭窄部分。过滤器膨胀，气囊在狭窄部分扩张。在从容器中取出可膨胀过滤器之前，产生栓塞材料，并被过滤元件捕获。版权所有（C）2004，JPO＆NCIPI

3. 发明申请

WO2007134290A8 IMPLANT AND DELIVERY SYSTEM WITH MULTIPLE MARKER INTERLOCKS 审中-公开
标题翻译：具有多个标记交错的植入和传送系统
公开(公告)号：WO2007134290A8
公开(公告)日：2014-03-20
申请号：PCT/US2007068882
申请日：2007-05-14
申请人： EV3 INC
发明人： WANG LIXIAO , MA JIANLU , TATALOVICH JOE , WALTZ PEGGY , SMYTHE KEITH
CPC分类号： A61F2/962 , A61F2/91 , A61F2/915 , A61F2/95 , A61F2002/91541 , A61F2002/91558 , A61F2002/91591 , A61F2002/9522 , A61F2002/9665 , A61F2220/005 , A61F2220/0058 , A61F2230/0054 , A61F2250/0098
摘要： An implant delivery system has one or more interlock assemblies which connect the implant delivery catheter to the implant, an improved inner tubular member and an outer tubular member. The interlock assemblies, improved inner tubular member and outer tubular member cooperate to place the implant in tension during deployment, thereby reducing implant deployment force.
摘要翻译：植入物递送系统具有将植入物输送导管连接到植入物的一个或多个互锁组件，改进的内部管状构件和外部管状构件。联锁组件，改进的内部管状构件和外部管状构件协调以在展开期间使植入物处于张力状态，从而减少植入物展开力。

4. 发明申请

WO2008021254A2 RAPID EXCHANGE CATHETERS FOR EMBOLIC PROTECTION DEVICES 审中-公开
标题翻译：快速交换导管用于插入式保护装置
公开(公告)号：WO2008021254A2
公开(公告)日：2008-02-21
申请号：PCT/US2007/017820
申请日：2007-08-10
申请人： EV3 INC.
发明人： QUINN, Christopher , BAKKER, Sara , ZAVER, Steven , SIRIVONG, Sengkham
IPC分类号： A61F2/01 , A61M25/01
CPC分类号： A61F2/01 , A61F2002/011 , A61F2002/018 , A61F2230/0008 , A61F2230/0067 , A61M2025/0183
摘要： Catheter having a first elongate tubular body having a lumen, a second elongate tubular body having a lumen, and an elongate member. The elongate member joins the first and second elongate tubular bodies. The first tubular body is fixedly attached on the distal portion of the elongate member, and the second elongate tubular body is disposed on the elongate member is slidable along a portion of the elongate member. The second elongate tubular body can be in a first position so that the first and second tubular bodies are not adjacent to each other and can be in a second position so that the first and second tubular bodies are adjacent to each other. The catheter may have a locking mechanism that can lock the first and second elongate tubular bodies to each other so that the lumens of the first and second elongate tubular bodies form one continuous lumen.
摘要翻译：导管具有具有内腔的第一细长管状主体，具有内腔的第二细长管状主体和细长构件。细长构件连接第一和第二细长管状体。第一管状体固定地附接在细长构件的远侧部分上，并且第二细长管状体布置在细长构件上可沿着细长构件的一部分滑动。第二细长管状体可处于第一位置，使得第一和第二管状体彼此不相邻，并且可处于第二位置，使得第一和第二管状体彼此相邻。导管可具有锁定机构，该锁定机构可将第一和第二细长管状体彼此锁定，使得第一和第二细长管状体的内腔形成一个连续内腔。

5. 发明申请

WO2007134290A2 IMPLANT AND DELIVERY SYSTEM WITH MULTIPLE MARKER INTERLOCKS 审中-公开
标题翻译：具有多个标记交错的植入和传送系统
公开(公告)号：WO2007134290A2
公开(公告)日：2007-11-22
申请号：PCT/US2007/068882
申请日：2007-05-14
申请人： EV3, INC.
发明人： WANG, Lixiao , MA, Jianlu , TATALOVICH, Joe , WALTZ, Peggy , SMYTHE, Keith
IPC分类号： A61F2/90 , B23K26/40 , B23K26/06
CPC分类号： A61F2/962 , A61F2/91 , A61F2/915 , A61F2/95 , A61F2002/91541 , A61F2002/91558 , A61F2002/91591 , A61F2002/9522 , A61F2002/9665 , A61F2220/005 , A61F2220/0058 , A61F2230/0054 , A61F2250/0098
摘要： An implant delivery system has one or more interlock assemblies which connect the implant delivery catheter to the implant, an improved inner tubular member and an outer tubular member. The interlock assemblies, improved inner tubular member and outer tubular member cooperate to place the implant in tension during deployment, thereby reducing implant deployment force.
摘要翻译：植入物递送系统具有将植入物输送导管连接到植入物的一个或多个互锁组件，改进的内部管状构件和外部管状构件。联锁组件，改进的内部管状构件和外部管状构件协调以在展开期间使植入物处于张力状态，从而减少植入物展开力。

6. 发明申请

WO2007126931A2 EMBOLIC PROTECTION DEVICES HAVING RADIOPAQUE MARKERS 审中-公开
标题翻译：具有无线电标记的嵌入式保护装置
公开(公告)号：WO2007126931A2
公开(公告)日：2007-11-08
申请号：PCT/US2007007733
申请日：2007-03-28
申请人： EV3 INC
发明人： ZAVER STEVEN , SIRIVONG SENGKHAM , QUINN CHRISTOPHER , SLEE EARL , ANDERSON LINDA
IPC分类号： A61F2/01
CPC分类号： A61F2/013 , A61B90/39 , A61B2090/3966 , A61F2/01 , A61F2002/018 , A61F2230/0008 , A61F2230/0067 , A61F2250/0098
摘要： Abstract A device for filtering emboli from blood flowing through a lumen defined by the walls of a vessel in a patient's body, comprising: a filter element being expandable from a collapsed configuration when the filter element is restrained to an expanded configuration when the filter element is unrestrained, and an elongate support member, the filter being carried on a portion of the elongate support member, wherein the filter element has proximal and distal portions and a central portion, the filter element having a shape in the expanded configuration which defines a cavity having a proximal facing opening, and wherein the proximal portion of the filter element comprises a radiopaque element in the form of a discontinuous loop extending around a portion of a perimeter of the proximal facing opening, the discontinuous loop having a gap and the gap being proximate to the elongate support member.
摘要翻译：摘要一种用于过滤栓塞血液的装置，该血液流过由患者体内的血管壁限定的内腔，包括：过滤元件，当过滤元件为所述过滤器承载在所述细长支撑构件的一部分上，其中所述过滤元件具有近端部分和远端部分以及中心部分，所述过滤器元件具有处于膨胀构型的形状，所述形状限定了具有近侧面向的开口，并且其中过滤器元件的近端部分包括不连续环形的形式的不透射线的元件，该不连续环绕着近侧面对的开口的周边的一部分延伸，所述不连续的环具有间隙，并且所述间隙接近细长的支撑构件。

7. 发明申请

WO2006126979A3 SYSTEM AND METHOD FOR DELIVERING A LEFT ATRIAL APPENDAGE CONTAINMENT DEVICE 审中-公开
公开(公告)号：WO2006126979A3
公开(公告)日：2006-11-30
申请号：PCT/US2004/040642
申请日：2004-12-03
申请人： EV3, INC. , VAN DE BURG, Erik, J. , STEWART, Kume, M.
发明人： VAN DE BURG, Erik, J. , STEWART, Kume, M.
IPC分类号： A61F2/01
摘要： A method of delivering and deploying the device for containing the emboli during a surgical procedure proximate to the heart. Access is gained to the heart and the left atrium such that a distal end of the delivery sheath can be located near the left atrial appendage. A distal end of a delivery catheter can be loaded with the device in a collapsed position and passed through the delivery sheath thereby delivering the device within the left atrial appendage. The device is expanded to contain emboli in the left atrium appendage.

8. 发明申请

WO2005053573A1 RAPID EXCHANGE CATHETERS WITH TANDEM LUMENS 审中-公开
标题翻译：快速交换电缆，带TANDEM LUMENS
公开(公告)号：WO2005053573A1
公开(公告)日：2005-06-16
申请号：PCT/US2004/039443
申请日：2004-11-24
申请人： EV3 INC.
发明人： CLUBB, Thomas
IPC分类号： A61F2/01
CPC分类号： A61F2/013 , A61F2002/011 , A61F2230/0006 , A61F2230/0008 , A61M2025/0183
摘要： A catheter having a proximal portion and a distal portion comprising: a first elongate tubular body; a second elongate tubular body; and an elongate member joining the first and second elongate bodies. The first elongate tubular body is disposed proximal and tandem to the second elongate tubular body, and the first and second tubular bodies are permanently disposed so that the first and second tubular bodies are not adjacent to each other. The catheter also comprises a third elongate tubular body, at least the proximal portion of the third elongate tubular body being disposed within the lumen of the first elongate tubular body, the third elongate tubular body being slidable within the lumen of the first elongate tubular body, and the distal portion of the third elongate tubular body being able to be disposed in the lumen of the second elongate tubular body.
摘要翻译：具有近端部分和远端部分的导管包括：第一细长管状体; 第二细长管状体; 以及连接第一和第二细长体的细长构件。第一细长管状体被设置为与第二细长管状体近端并串联，并且第一和第二管状体永久地设置成使得第一和第二管状体彼此不相邻。所述导管还包括第三细长管状体，所述第三细长管状体的至少近端部分设置在所述第一细长管状体的内腔内，所述第三细长管状体可在所述第一细长管状体的内腔内滑动，并且第三细长管状体的远端部分能够设置在第二细长管状体的内腔中。

9. 发明申请

WO2004069098A2 EMBOLIC FILTERS WITH CONTROLLED PORE SIZE 审中-公开
标题翻译：具有控制孔径的EMBOLIC过滤器
公开(公告)号：WO2004069098A2
公开(公告)日：2004-08-19
申请号：PCT/US2004/002587
申请日：2004-01-30
申请人： EV3 INC.
发明人： CLUBB, Thomas , KUSLEIKA, Richard , ANDERSON, Kent , BERRADA, Marwane
IPC分类号： A61F2/01
CPC分类号： A61F2/01 , A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0008 , A61F2230/0067 , A61F2230/0069 , A61F2230/008 , D04B1/16 , D04C1/02 , D04C3/48 , D10B2509/06
摘要： The invention provides a device for filtering emboli from blood flowing through a lumen defined by the walls of a vessel in a patient's body comprising a filter element. The filter is expandable from a collapsed configuration when the filter element is restrained to an expanded configuration when the filter element is unrestrained, and the filter element comprises a self-expanding material having pores. When the filter element is in the expanded configuration, the average pore size is from 30 to 300 microns and the standard deviation of the pore size is less than 20 percent of the average pore size.
摘要翻译：本发明提供了一种用于从血液流过血管的装置，该装置包括由包含过滤元件的患者体内的容器壁限定的内腔。当过滤元件不受限制时，过滤元件被限制到膨胀构型，并且过滤元件包括具有孔的自膨胀材料时，过滤器可从折叠构型扩展。当过滤元件处于膨胀构型时，平均孔径为30至300微米，孔径的标准偏差小于平均孔径的20％。

10. 发明申请

WO03082151A2 EVERTING STENT AND STENT DELIVERY SYSTEM 审中-公开
标题翻译：有史以来的STENT和STENT交付系统
公开(公告)号：WO03082151A2
公开(公告)日：2003-10-09
申请号：PCT/US0307407
申请日：2003-03-11
申请人： EV3 INC
发明人： KUSLEIKA RICHARD S
IPC分类号： A61F2/06
CPC分类号： A61F2/962 , A61F2/82 , A61F2/95 , A61F2/966
摘要： Devices and methods for delivering stents to target vessel regions, including stent delivery through microcatheters to narrow cerebral arteries. One stent delivery device includes a stent having the distal region everted over the distal end of a delivery tube, having the everted stent distal end captured by a distal element of a elongate release member disposed through the delivery tube. The delivery tube can have a distal taper to a small profile distal end. The everted stent distal region can be captured between the release member distal element and the surrounding delivery tube distal region walls. The captured and everted stent can be distally advanced to a target site, followed by manipulating the release member to free the captured stent. Some devices utilize distal advancement of the release member while other devices use proximal retraction of the release member to free the captured stent distal end. Once released, the stent is free to self-expand or be expanded against the surrounding blockage and/or vessel walls. In some methods, a guide catheter or microcatheter is also included and disposed about the everted and captured stent to advance the stent, delivery tube, and release member to a location near the site to be stented. The devices and methods provide stent delivery not requiring an enclosing delivery sheath about the stent. The everted stent can thus have a very small distal profile enabling small diameter vessels to be crossed and treated.
摘要翻译：用于将支架输送到靶血管区域的装置和方法，包括支架通过微导管递送至狭窄的脑动脉。一个支架输送装置包括支架，该支架具有远离输送管的远端的远侧区域，其具有由经由输送管设置的细长释放构件的远端元件捕获的经过的支架远端。输送管可以具有远端锥形到小轮廓远端。转位的支架远侧区域可以被捕获在释放构件远端元件和周围的输送管远侧区域壁之间。捕获的和断端的支架可以远端前进到目标部位，随后操纵释放构件以释放被捕获的支架。一些装置利用释放构件的远端前进，而其他装置使用释放构件的近端缩回以释放被捕获的支架远端。一旦释放，支架可自由扩张或扩大到周围的阻塞和/或血管壁。在一些方法中，引导导管或微导管还包括并布置在绕过和捕获的支架周围，以将支架，输送管和释放构件推进到待固定位点附近的位置。这些装置和方法提供了不需要关于支架的封闭输送护套的支架输送。因此，转角支架可以具有非常小的远端轮廓，使得能够交叉和处理小直径的血管。

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