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1. 发明专利

HK1103370A1 RESPIRATORY DEVICES AND METHODS OF USE 未知
公开(公告)号：HK1103370A1
公开(公告)日：2007-12-21
申请号：HK07111680
申请日：2007-10-30
申请人： THERAVENT INC
发明人： HATANAKA MOTOHIDE , HOWARD ROBERT A , DOSHI RAJIV
IPC分类号： A61M20060101
摘要： Described here are devices for altering the flow of air in a respiratory cavity such as the mouth and nostrils of the nose. These methods and devices may be useful for affecting a physiologic benefit in patients suffering from a variety of medical diseases, particularly those that may benefit from pursed-lip breathing and non-invasive ventilation, such as COPD, heart failure, sleep apnea, and other medical disorders. The devices are typically removable devices that may be placed over or in a respiratory cavity to increase resistance to airflow within the respiratory cavity. Resistance to expiration may be selectively increased relative to inspiration. Removable oral and removable nasal devices are described. Oral and nasal devices that filter inhaled airflow of debris and allergens are also provided. A nasal device that increases patency of the nares is also provided.

2. 发明授权

US08707955B2 Methods and devices for improving breathing in patients with pulmonary disease 有权
标题翻译：改善肺部疾病患者呼吸的方法和装置
公开(公告)号：US08707955B2
公开(公告)日：2014-04-29
申请号：US13164705
申请日：2011-06-20
申请人： Rajiv Doshi
发明人： Rajiv Doshi
IPC分类号： A61M11/00
CPC分类号： A63B23/18 , A61B17/12036 , A61B17/12104 , A61B17/12172 , A61B17/12177 , A61B17/24 , A61F2/24 , A61F2002/043 , A61M16/0488 , A61M16/0493 , A61M16/06 , A61M16/20 , A61M16/208
摘要： Methods, apparatus, and kits for enhancing breathing in patients suffering from chronic pulmonary obstructive disease are described. The methods and apparatus rely on increasing flow resistance to expiration in a manner which mimics “pursed lip” breathing which has been found to benefit patients suffering from this disease. In a first example, a device is implanted in a trachea or bronchial passage to increase flow resistance, preferably selectively increase resistance to expiration relative to inspiration. In a second embodiment, a mouthpiece is provided, again to increase resistance to expiration, preferably with a lesser increase in flow resistance to inspiration. In a third embodiment, the patient's trachea or bronchial passage is modified by the application of energy in order to partially close the lumen therethrough.
摘要翻译：描述了用于增强患有慢性肺动脉阻塞性疾病的患者呼吸的方法，装置和试剂盒。方法和装置依赖于以模仿“追求唇”呼吸的方式增加流出阻力，已被发现有利于患有这种疾病的患者。在第一示例中，将装置植入气管或支气管通道中以增加流动阻力，优选地选择性地增加相对于吸气的抵抗力。在第二个实施例中，提供一个接口件，以再次增加对呼气的阻力，优选地，对吸气的流动阻力的增加较小。在第三实施例中，通过施加能量来改变患者的气管或支气管通道，以便部分地关闭通过其中的内腔。

3. 发明公开

EP2032214A4 LAYERED NASAL DEVICES 有权
标题翻译： NASALE层设备
公开(公告)号：EP2032214A4
公开(公告)日：2014-02-19
申请号：EP07809407
申请日：2007-06-07
申请人： THERAVENT INC
发明人： DOSHI RAJIV , LOOMAS BRYAN , PIERCE RYAN KENDALL , FERDINAND ARTHUR , SANDOVAL ARTHUR G , SERVAITES JEFFREY W , DURACK MATTHEW , KENNEDY DANIEL FRANCIS
IPC分类号： A62B23/06 , A61F5/56 , A61M16/20
CPC分类号： A62B23/06 , A61F5/08 , A61F5/56 , A61M15/08 , A61M15/085 , A61M16/0616 , A61M16/0688 , A61M16/0866 , A61M16/106 , A61M16/208
摘要： Described herein are adhesive nasal devices. In particular, the adhesive nasal respiratory devices described herein are configured to be worn in communication with a subject's nasal cavity and may include a rim body having a passageway therethrough, an airflow resistor in communication with the passageway of the rim body, and a flexible, adhesive holdfast layer extending outward from the periphery of the rim body. The rim body region may be formed from multiple parts (e.g., a first and a second rim body region), and the airflow resistor may be secured between the parts forming the rim body. Methods of manufacturing and assembling these adhesive nasal devices are also described.

4. 发明授权

US09833354B2 Nasal respiratory devices 有权
公开(公告)号：US09833354B2
公开(公告)日：2017-12-05
申请号：US14997870
申请日：2016-01-18
申请人： Theravent, Inc.
发明人： Bryan Loomas , Rajiv Doshi , Ryan Kendall Pierce , Robert A. Howard , Motohide Hatanaka
IPC分类号： A61F5/56 , A61M15/08 , A61M15/00 , A61M16/00 , A62B23/06
CPC分类号： A61F5/56 , A61M15/002 , A61M15/08 , A61M2016/0027 , A61M2016/003 , A61M2210/0618 , A62B23/06
摘要： Devices for altering the flow of air in a respiratory cavity such as the nostrils of the nose. These methods and devices may be useful for affecting a physiologic benefit in patients suffering from a variety of medical disorders, including snoring and sleep apnea. The devices are typically removable devices that may be placed in both nostrils to increase resistance to airflow within the respiratory cavity. Resistance to expiration may be selectively increased relative to inspiration. The nasal devices may also increases patency of the nares. Any of these devices may be configured to achieve positive end-expiratory pressure (PEEP) in a subject wearing the device.

5. 发明授权

US09238113B2 Nasal respiratory devices for positive end-expiratory pressure 有权
标题翻译：鼻呼吸器官用于呼气末正压
公开(公告)号：US09238113B2
公开(公告)日：2016-01-19
申请号：US12877836
申请日：2010-09-08
申请人： Bryan Loomas , Rajiv Doshi , Ryan Kendall Pierce , Robert A. Howard , Motohide Hatanaka
发明人： Bryan Loomas , Rajiv Doshi , Ryan Kendall Pierce , Robert A. Howard , Motohide Hatanaka
IPC分类号： A61M15/08 , A61M15/00 , A61M16/00
CPC分类号： A61M15/08 , A61M15/002 , A61M15/085 , A61M2016/0027 , A61M2016/003 , A61M2210/0618
摘要： Described herein are nasal respiratory devices, in particular, nasal respiratory devices configured to achieve positive end-expiratory pressure (PEEP) in a subject wearing the device. PEEP devices may have a threshold pressure for opening during expiration. In some variations, these devices have a threshold pressure for closing during expiration.
摘要翻译：这里描述的是鼻呼吸装置，特别是构造成在佩戴该装置的受试者中实现呼气末正压（PEEP）的鼻呼吸装置。 PEEP装置可能具有用于在呼气期间打开的阈值压力。在一些变型中，这些装置具有在到期期间关闭的阈值压力。

6. 发明公开

EP2032213A4 NASAL DEVICES 审中-公开
标题翻译： VORRICHTUNGENFÜRDIE NASE
公开(公告)号：EP2032213A4
公开(公告)日：2014-02-19
申请号：EP07795956
申请日：2007-06-07
申请人： THERAVENT INC
发明人： DOSHI RAJIV , LOOMAS BRYAN , PIERCE RYAN KENDALL , SATHER ELLIOT , SANDOVAL ARTHUR G , SERVAITES JEFFREY W , LABAS SANDRINE , DURACK MATTHEW
IPC分类号： A62B7/10 , A61F5/56 , A61M16/20
CPC分类号： A62B23/06 , A61F5/08 , A61F5/56 , A61M15/08 , A61M15/085 , A61M16/0616 , A61M16/0688 , A61M16/0866 , A61M16/106 , A61M16/208

7. 发明授权

EP2249907B1 CPAP INTERFACE AND BACKUP DEVICES 无效
标题翻译： CPAP接口和备份设备
公开(公告)号：EP2249907B1
公开(公告)日：2013-09-04
申请号：EP09709315
申请日：2009-02-02
申请人： THERAVENT INC
发明人： DOSHI RAJIV , FERDINAND ARTHUR , SATHER ELLIOT , FAVET MICHAEL L , LAI DANNY YU-YOUH , MINO TORU
IPC分类号： A61M16/06 , A61M16/00 , A61M16/20
CPC分类号： A61M16/0051 , A61M16/0066 , A61M16/021 , A61M16/0666 , A61M16/0683 , A61M16/0816 , A61M16/0866 , A61M16/205 , A61M16/208 , A61M2205/0216

8. 发明申请

US20160361067A9 PASSIVE NASAL PEEP DEVICES 审中-公开
标题翻译：被动的NASAL PEEP设备
公开(公告)号：US20160361067A9
公开(公告)日：2016-12-15
申请号：US14071582
申请日：2013-11-04
申请人： Theravent, Inc.
发明人： Benjamin K. CLINE , Ronald G. FRENCH , Frank W. WANG , Rajiv DOSHI , Ryan K. PIERCE
IPC分类号： A61B17/12 , A61M16/06 , A61B5/087 , A61B5/097 , A61M15/08 , A61M16/20
CPC分类号： A61B17/12104 , A61B5/0871 , A61B5/097 , A61F5/08 , A61F5/56 , A61M15/08 , A61M16/06 , A61M16/0666 , A61M16/0683 , A61M16/208 , A61M2210/0618
摘要： Described herein are passive nasal respiratory devices, in particular, passive nasal respiratory devices configured to achieve positive end-expiratory pressure (PEEP) in a subject wearing the device. PEEP devices may have a threshold pressure for opening during expiration. These devices may include a flap valve that opens on inhalation nested with a spring valve that opens when exhalation pressure exceeds a predetermined threshold. The device may be configured to be comfortably worn by a sleeping subject.
摘要翻译：本文描述的是被动鼻呼吸装置，特别是配置成在佩戴该装置的受试者中获得正呼气末压力（PEEP）的被动鼻呼吸装置。 PEEP装置可能具有用于在呼气期间打开的阈值压力。这些装置可以包括瓣膜阀，其在吸入时开启，弹簧阀嵌套，当呼气压力超过预定阈值时打开。该装置可以被配置为被睡觉的对象舒适地佩戴。

9. 发明授权

US08985116B2 Layered nasal devices 有权
标题翻译：分层鼻装置
公开(公告)号：US08985116B2
公开(公告)日：2015-03-24
申请号：US11759916
申请日：2007-06-07
申请人： Rajiv Doshi , Bryan Loomas , Ryan Kendall Pierce , Arthur Ferdinand , Arthur G. Sandoval , Jeffrey W. Servaites , Matthew Durack , Daniel Francis Kennedy
发明人： Rajiv Doshi , Bryan Loomas , Ryan Kendall Pierce , Arthur Ferdinand , Arthur G. Sandoval , Jeffrey W. Servaites , Matthew Durack , Daniel Francis Kennedy
IPC分类号： A61M11/00 , A61M16/06 , A62B23/06 , A61M16/08 , A61M16/20 , A61M16/10 , A61F5/08 , A61M15/08 , A61F5/56
CPC分类号： A62B23/06 , A61F5/08 , A61F5/56 , A61M15/08 , A61M15/085 , A61M16/0616 , A61M16/0688 , A61M16/0866 , A61M16/106 , A61M16/208
摘要： Described herein are nasal devices. In particular, layered nasal respiratory devices are described. Layered nasal device may include a layered airflow resistor that is configured to resist airflow in a first direction more than airflow in a second direction and that includes a flap valve adjacent to a flap valve limiting layer and an adhesive holdfast layer that is configured to secure the layered airflow resistor in communication with the subject's nasal cavity. Methods of using and methods of assembling layered nasal device are also described.
摘要翻译：这里描述的是鼻装置。特别地，描述了分层的鼻呼吸装置。层状鼻装置可以包括分层气流阻力器，其被配置成抵抗第一方向上的气流，而不是沿着第二方向的气流，并且包括与瓣阀限制层相邻的瓣阀和被配置成固定分层气流电阻器与受试者的鼻腔连通。还描述了使用方法和组装分层鼻装置的方法。

10. 发明授权

US08875711B2 Layered nasal respiratory devices 有权
标题翻译：分层鼻呼吸器
公开(公告)号：US08875711B2
公开(公告)日：2014-11-04
申请号：US13117933
申请日：2011-05-27
申请人： Elliot Sather , Arthur Ferdinand , Michael L. Favet , Danny Yu-Youh Lai , Rajiv Doshi
发明人： Elliot Sather , Arthur Ferdinand , Michael L. Favet , Danny Yu-Youh Lai , Rajiv Doshi
IPC分类号： A61M11/00 , A61M16/08 , A61M16/20 , A61F5/08 , A61M16/06 , A61F5/56
CPC分类号： A61M16/208 , A61F5/08 , A61F5/56 , A61M16/0605 , A61M16/0688 , A61M16/0866 , A61M2205/0216 , A61M2205/0238 , A61M2210/0618 , Y10T29/49826 , Y10T156/1064
摘要： Described herein are nasal devices, including nasal devices formed in layers having four or fewer layers. In some variations, the nasal devices include a single integrated layer from which the flap of the airflow resistor is formed as well as the base of the holdfast region. The nasal devices may include a single aligner or rim body on the side of the device facing the subject. The aligner may protect the airflow resistor, and may help center or position the nasal device. In some variations, these nasal devices may include a noise-reduction feature. Also described herein are systems, devices and methods for determining if a passive nasal respiratory device having an airflow resistor configured to inhibit exhalation more than inhalation has been worn by a subject, and thereby confirming compliance.
摘要翻译：这里描述的是鼻装置，包括以具有四层或更少层的层形成的鼻装置。在一些变型中，鼻部装置包括形成气流阻力器的翼片的单个整体层以及保持区域的基部。鼻部装置可以包括在面向对象的装置一侧上的单个对准器或边缘体。对准器可以保护气流阻力器，并且可以帮助中心或定位鼻部装置。在一些变型中，这些鼻装置可以包括降噪特征。本文还描述了用于确定具有被配置为抑制呼吸多于吸入的气流电阻器的被动鼻呼吸装置的系统，装置和方法已被受试者佩戴，从而确认顺应性。

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