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1. 发明申请

WO2009152582A1 PHYSICAL MODEL EYE SYSTEMS AND METHODS 审中-公开
标题翻译：物理模型眼睛系统和方法
公开(公告)号：WO2009152582A1
公开(公告)日：2009-12-23
申请号：PCT/AU2009/000791
申请日：2009-06-17
申请人： THE INSTITUTE FOR EYE RESEARCH LIMITED , EHRMANN, Klaus , BAKARAJU, Ravi Chandra , FALK, Darrin
发明人： EHRMANN, Klaus , BAKARAJU, Ravi Chandra , FALK, Darrin
IPC分类号： A61B3/00 , G09B23/22
CPC分类号： G09B23/22 , A61B3/0025 , G09B23/34
摘要： An optically and physically representative model eye (50, Figure 3) is employed in a model eye system to evaluate corrective lenses and corneal modification. The illustrative model eye (50) has a mounting ring (52) that holds a simulated cornea (54), iris (56) and lens (58). A photoactive device (64) such as a photodetector array (65) is mounted on a movable base (66) for movement within a retinal area (70). A liquid-tight posterior enclosure (72) is formed by a flexible tubular bladder (73) so that the device is immersed in a liquid that simulates optical properties of the natural vitreous humor. The base (66) and photodetector array (65) are moved by rotary and linear actuators (not shown in Figure 3) to position the device angularly within the retinal area (70) and to reciprocate it to achieve through-focus at any position in the retinal area (70). A conventional eye-test chart (91) in a field of view (69) can be imaged via a mirror (92) and a test contact lens can be placed on the model cornea (54) with a simulated tear solution under a protective cover (84). A camera (87) can be used to check the alignment and orientation of the test lens.
摘要翻译：在模型眼睛系统中使用光学和物理上代表性的模型眼（50，图3）来评估矫正镜片和角膜修改。示例性眼睛（50）具有保持模拟角膜（54），虹膜（56）和透镜（58）的安装环（52）。诸如光电检测器阵列（65）的光敏装置（64）安装在可移动基座（66）上，用于在视网膜区域（70）内移动。液体密封的后外壳（72）由柔性管状囊（73）形成，使得该装置浸入模拟天然玻璃体液的光学性质的液体中。基部（66）和光电检测器阵列（65）通过旋转和线性致动器（图3中未示出）移动，以将装置成角度地定位在视网膜区域（70）内并使其往复运动以在任何位置视网膜区域（70）。在视场（69）中的常规眼睛测试图（91）可以通过反射镜（92）成像，并且可以在模型角膜（54）上放置测试隐形眼镜，模拟眼泪液在保护罩下方（84）。相机（87）可用于检查测试镜头的对准和方位。

2. 发明申请

WO2008131479A1 DETERMINATION OF OPTICAL ADJUSTMENTS FOR RETARDING MYOPIA PROGRESSION 审中-公开
标题翻译：确定用于延缓MYOPIA进展的光学调整
公开(公告)号：WO2008131479A1
公开(公告)日：2008-11-06
申请号：PCT/AU2008/000572
申请日：2008-04-28
申请人： THE INSTITUTE FOR EYE RESEARCH LIMITED , EHRMANN, Klaus , HO, Arthur
发明人： EHRMANN, Klaus , HO, Arthur
IPC分类号： A61B3/10
CPC分类号： A61B3/103 , A61B3/0025 , A61F9/00802 , A61F9/00804 , A61F9/00806 , A61F2009/00872 , G02C7/02 , G02C7/04 , G02C7/042 , G02C7/061 , G02C2202/24 , G06F19/00
摘要： A method or process (40) for providing an anti-myopia lens or treatment for a patient's eye with progressive myopia, which involves (in one form) generating biometric data (42) relating to the central and peripheral refractive errors of the eye, optionally together with data relating to the patient's visual or lifestyle needs (44) and the patient's predisposition to progressive myopia (46). This data is input to a processor or algorithm (48) that generates a basic lens design (51 ), a customised design (53) or a program (55) for reshaping the cornea of the eye. The selected modality (52, 54 or 56) is applied to the patient (60) and its suitability is assessed (62, 50) with the result of the assessment feedback to the algorithm (48) to generate a refined output design (52, 54 or 56), which is applied to the patient. The process is repeated at intervals to check continued myopia progression and adjust the design of the selected modality after further measurement.
摘要翻译：一种用于提供抗近视眼镜或用于进行性近视治疗患者眼睛的方法或过程（40），其包括（以一种形式）生成与眼睛的中心和周边屈光不正有关的生物特征数据（42），任选地以及与患者视力或生活方式需求相关的数据（44）和患者对进行性近视的倾向（46）。该数据被输入到生成用于重新整形眼睛的角膜的基本透镜设计（51），定制设计（53）或程序（55）的处理器或算法（48）。所选择的模式（52,54或56）被应用于患者（60），并且其评估适应性（62,50），其中对算法（48）进行评估反馈的结果以产生精细的输出设计（52， 54或56），其被应用于患者。间隔重复该过程以检查持续近视进展，并在进一步测量后调整所选模态的设计。

3. 发明申请

WO2009129528A1 MYOPIA CONTROL MEANS 审中-公开
标题翻译： MYOPIA控制手段
公开(公告)号：WO2009129528A1
公开(公告)日：2009-10-22
申请号：PCT/US2009/041103
申请日：2009-04-20
申请人： NOVARTIS AG , THE INSTITUTE FOR EYE RESEARCH LIMITED , MARTINEZ, Aldo, Abraham , HO, Arthur , SANKARIDURG, Padmaja, Rajagopal , LAZON, Percy, Fabian , HOLDEN, Brien, Anthony , PAYOR, Rick, Edward , SCHMID, Gregor, F.
发明人： MARTINEZ, Aldo, Abraham , HO, Arthur , SANKARIDURG, Padmaja, Rajagopal , LAZON, Percy, Fabian , HOLDEN, Brien, Anthony , PAYOR, Rick, Edward , SCHMID, Gregor, F.
IPC分类号： G02C7/02 , G02C7/04
CPC分类号： G02C7/06 , A61B3/0025 , G02C7/02 , G02C7/027 , G02C7/04 , G02C7/041 , G02C7/044 , G02C13/003 , G02C2202/08 , G02C2202/16 , G02C2202/24
摘要： Sets, kits or stocks of anti-myopia contact or spectacle lenses, along with methods for their use, that do not require a clinician to measure peripheral refractive error in the eyes of myopic patients. Extensive surveys have shown that lenses having peripheral powers or defocus set in accordance with central corrective power will cover almost all normal myopes not worse than -6D central refractive error. In one example, a kit or set of lenses (50, Figure 15) can have multiple parts or sub-sets (52, 54) each comprising a compartmented container (56a, 56b) with lenses (58a, 58b) arranged according to increments of central corrective power (59a, 59b). The lenses (58a) of the first part (52) have four steps (60a, 61a, 62a, 64a) of peripheral power or defocus to provide therapeutic effect and, while the lenses (58b) of the second part (54) also have four steps (60b, 61b, 62b, 64b), the level of therapeutic effect is higher. Other examples of sets, kits and stocks, as well as examples of lenses themselves, are disclosed together with methods of use.
摘要翻译：抗近视接触眼镜镜片的套件，套件或库存，以及使用方法，不需要临床医生测量近视患者眼睛的周边屈光不正。广泛的调查显示，具有根据中心矫正力设置的外围功率或散焦的镜片将覆盖几乎所有正常的近视眼，不会比-6D中心屈光不正差。在一个示例中，套件或一组透镜（50，图15）可以具有多个部件或子组件（52,54），每个部件或子组件包括具有根据增量布置的透镜（58a，58b）的分隔的容器（56a，56b）的中央矫正力（59a，59b）。第一部分（52）的透镜（58a）具有周边功率或散焦的四个台阶（60a，61a，62a，64a），以提供治疗效果，并且当第二部分（54）的透镜（58b）也具有四个步骤（60b，61b，62b，64b），治疗效果水平较高。集合，套件和股票的其他示例以及透镜本身的示例与所使用的方法一起公开。

4. 发明申请

WO2008116270A1 CHARACTERISING EYE-RELATED OPTICAL SYSTEMS 审中-公开
标题翻译：表征与眼睛相关的光学系统
公开(公告)号：WO2008116270A1
公开(公告)日：2008-10-02
申请号：PCT/AU2008/000434
申请日：2008-03-28
申请人： THE INSTITUTE FOR EYE RESEARCH LIMITED , EHRMANN, Klaus , HO, Arthur , HOLDEN, Brien, Anthony
发明人： EHRMANN, Klaus , HO, Arthur , HOLDEN, Brien, Anthony
IPC分类号： A61B3/103
CPC分类号： A61B3/103 , A61B3/0008 , A61B3/1005 , A61B3/1015
摘要： An instrument and method for characterising eye-related optical systems, including the live human eye (18) involves scanning an illuminating light beam (22) from a light source and light detector unit (20) from element to element of a beam deflector array (12) of elements (14) arranged laterally across the optical axis (16) of eye (18). At each successive element (14) the illuminating beam (22) is deflected to form an interrogating beam (24) that is directed into the eye (18) at a peripheral angle that depends upon the lateral location of the deflector element. A return beam (23) is reflected or back-scattered from the cornea (38) and returned via the same deflector element to the light source and detector unit (20). This allows the interrogating beams to be scanned sufficiently rapidly into the eye to greatly reduce the variation of eye fixation and gaze that accompany other methods of measuring peripheral refraction or aberration of a natural eye. In addition to or instead of scanning the illuminating beam (22) over each element (14) of the array (12), all or multiple elements (14) of the array (12) can be illuminated simultaneously and the multiple interrogating rays (24) thus generated can be gated by the use of an LCD aperture plate (26). Alternatively, an LCD aperture plate (28) can be interposed between a wide illuminating beam (22) and operated to selectively illuminate the beam deflector.
摘要翻译：用于表征包括活人眼（18）的眼睛相关光学系统的仪器和方法涉及从光源和光检测器单元（20）从光束偏转器阵列的元件到元件扫描照明光束（22） 12）横向穿过眼睛（18）的光轴（16）布置的元件（14）。在每个连续的元件（14）处，照明光束（22）被偏转以形成询问光束（24），其以取决于偏转器元件的横向位置的圆周角度被引导到眼睛（18）中。返回光束（23）从角膜（38）反射或反向散射并通过相同的偏转元件返回到光源和检测器单元（20）。这样就可以将询问光束快速扫描到眼睛中，以大大减少测量周边折射或自然眼睛畸变的其他测量方法的眼睛固定和注视的变化。除了扫描阵列（12）的每个元件（14）上的照明光束（22）之外或代替扫描阵列（12）的全部或多个元件（14）可同时被照射，并且多个询问光线（24 ）可以通过使用LCD孔板（26）来选通。或者，LCD孔板（28）可以插入在宽照明光束（22）之间并被操作以选择性地照射光束偏转器。

5. 发明公开

EP2155041A1 DETERMINATION OF OPTICAL ADJUSTMENTS FOR RETARDING MYOPIA PROGRESSION 审中-公开
标题翻译：光学调节的测定延缓近视的发展
公开(公告)号：EP2155041A1
公开(公告)日：2010-02-24
申请号：EP08733399.3
申请日：2008-04-28
申请人： The Institute For Eye Research Limited
发明人： EHRMANN, Klaus , HO, Arthur
IPC分类号： A61B3/10
CPC分类号： A61B3/103 , A61B3/0025 , A61F9/00802 , A61F9/00804 , A61F9/00806 , A61F2009/00872 , G02C7/02 , G02C7/04 , G02C7/042 , G02C7/061 , G02C2202/24 , G06F19/00
摘要： A method or process for providing an anti-myopia lens or treatment for a patient's eye with progressive myopia, which involves (in one form) generating biometric data relating to the central and peripheral refractive errors of the eye, optionally together with data relating to the patient's visual or lifestyle needs and the patient's predisposition to progressive myopia. This data is input to a processor or algorithm that generates a basic lens design, a customised design or a program for reshaping the cornea of the eye. The selected modality is applied to the patient and its suitability is assessed with the result of the assessment feedback to the algorithm to generate a refined output design, which is applied to the patient. The process is repeated at intervals to check continued myopia progression and adjust the design of the selected modality after further measurement.

6. 发明公开

EP2139381A1 CHARACTERISING EYE-RELATED OPTICAL SYSTEMS 审中-公开
标题翻译：表征光学系统与眼睛连接
公开(公告)号：EP2139381A1
公开(公告)日：2010-01-06
申请号：EP08714475.4
申请日：2008-03-28
申请人： The Institute For Eye Research Limited
发明人： EHRMANN, Klaus , HO, Arthur , HOLDEN, Brien, Anthony
IPC分类号： A61B3/103
CPC分类号： A61B3/103 , A61B3/0008 , A61B3/1005 , A61B3/1015
摘要： An instrument and method for characterising eye-related optical systems, including the live human eye (18) involves scanning an illuminating light beam (22) from a light source and light detector unit (20) from element to element of a beam deflector array (12) of elements (14) arranged laterally across the optical axis (16) of eye (18). At each successive element (14) the illuminating beam (22) is deflected to form an interrogating beam (24) that is directed into the eye (18) at a peripheral angle that depends upon the lateral location of the deflector element. A return beam (23) is reflected or back-scattered from the cornea (38) and returned via the same deflector element to the light source and detector unit (20). This allows the interrogating beams to be scanned sufficiently rapidly into the eye to greatly reduce the variation of eye fixation and gaze that accompany other methods of measuring peripheral refraction or aberration of a natural eye. In addition to or instead of scanning the illuminating beam (22) over each element (14) of the array (12), all or multiple elements (14) of the array (12) can be illuminated simultaneously and the multiple interrogating rays (24) thus generated can be gated by the use of an LCD aperture plate (26). Alternatively, an LCD aperture plate (28) can be interposed between a wide illuminating beam (22) and operated to selectively illuminate the beam deflector.

7. 发明公开

EP2114238A1 CHARACTERIZATION OF OPTICAL SYSTEMS 审中-公开
标题翻译：表征光学系统
公开(公告)号：EP2114238A1
公开(公告)日：2009-11-11
申请号：EP08706067.9
申请日：2008-02-14
申请人： The Institute For Eye Research Limited
发明人： EHRMANN, Klaus , HO, Arthur
IPC分类号： A61B3/103 , G01M11/02 , G02B27/00
CPC分类号： G01M11/0235 , A61B3/103 , A61B3/107 , G01M11/0257
摘要： An instrument and method for characterizing the optical properties of an optical system, such as a lens, another optical device or the human eye, over an optical surface of the optical system. In one example [Figure 1], an incident beam (16) is scanned over the surface of a lens (12) to generate an emergent beam (20) that is divided by a beam-splitter (22) into two portions (20a and 20b) that are directed to respective two-dimensional detector arrays (24 and 26) located at different optical distances from the lens (12). The detector arrays (24 and 26) output the lateral coordinates of the points of incidence of the respective emergent beam portions (20a and 20b) so that the angle of emergent beam (20) with respect to the optical axis (14) or incident beam (16) can be accurately determined. Determining the variation in the angle of the emergent beam over the surface of the lens allows many important optical characteristics of the lens to be characterized and mapped onto to the surface of the lens. Many novel variants of the instrument and methods are disclosed.

8. 发明授权

US08342684B2 Determination of optical adjustments for retarding myopia progression 有权
标题翻译：确定延迟近视进展的光学调整
公开(公告)号：US08342684B2
公开(公告)日：2013-01-01
申请号：US12597890
申请日：2008-04-28
申请人： Arthur Ho , Klaus Ehrmann
发明人： Arthur Ho , Klaus Ehrmann
IPC分类号： G02C7/02 , G02B7/00
CPC分类号： A61B3/103 , A61B3/0025 , A61F9/00802 , A61F9/00804 , A61F9/00806 , A61F2009/00872 , G02C7/02 , G02C7/04 , G02C7/042 , G02C7/061 , G02C2202/24 , G06F19/00
摘要： A method or process for providing an anti-myopia lens or treatment for a patient's eye with progressive myopia, which involves (in one form) generating biometric data relating to the central and peripheral refractive errors of the eye, optionally together with data relating to the patient's visual or lifestyle needs and the patient's predisposition to progressive myopia. This data is input to a processor or algorithm that generates a basic lens design, a customised design or a program for reshaping the cornea of the eye. The selected modality is applied to the patient and its suitability is assessed with the result of the assessment feedback to the algorithm to generate a refined output design, which is applied to the patient. The process is repeated at intervals to check continued myopia progression and adjust the design of the selected modality after further measurement.
摘要翻译：提供抗近视眼镜或用于进行性近视治疗患者眼睛的方法或过程，其涉及（以一种形式）产生与眼睛的中心和外周屈光不正相关的生物特征数据，可选地与数据有关的数据患者的视力或生活方式需求以及患者对进行性近视的倾向。该数据被输入到生成基本透镜设计，定制设计或用于重塑眼睛角膜的程序的处理器或算法。所选择的模式被应用于患者，并且其适用性被评估为对该算法的评估反馈的结果，以生成应用于患者的精细输出设计。间隔重复该过程以检查持续近视进展，并在进一步测量后调整所选模态的设计。

9. 发明申请

US20100296058A1 DETERMINATION OF OPTICAL ADJUSTMENTS FOR RETARDING MYOPIA PROGRESSION 有权
标题翻译：确定用于延缓MYOPIA进展的光学调整
公开(公告)号：US20100296058A1
公开(公告)日：2010-11-25
申请号：US12597890
申请日：2008-04-28
申请人： Arthur Ho , Klaus Ehrmann
发明人： Arthur Ho , Klaus Ehrmann
IPC分类号： A61B3/10 , G02C7/02 , A61F9/008
CPC分类号： A61B3/103 , A61B3/0025 , A61F9/00802 , A61F9/00804 , A61F9/00806 , A61F2009/00872 , G02C7/02 , G02C7/04 , G02C7/042 , G02C7/061 , G02C2202/24 , G06F19/00
摘要： A method or process for providing an anti-myopia lens or treatment for a patient's eye with progressive myopia, which involves (in one form) generating biometric data relating to the central and peripheral refractive errors of the eye, optionally together with data relating to the patient's visual or lifestyle needs and the patient's predisposition to progressive myopia. This data is input to a processor or algorithm that generates a basic lens design, a customised design or a program for reshaping the cornea of the eye. The selected modality is applied to the patient and its suitability is assessed with the result of the assessment feedback to the algorithm to generate a refined output design, which is applied to the patient. The process is repeated at intervals to check continued myopia progression and adjust the design of the selected modality after further measurement.
摘要翻译：提供抗近视眼镜或用于进行性近视治疗患者眼睛的方法或过程，其涉及（以一种形式）产生与眼睛的中心和外周屈光不正相关的生物特征数据，可选地与数据有关的数据患者的视力或生活方式需求以及患者对进行性近视的倾向。该数据被输入到生成基本透镜设计，定制设计或用于重塑眼睛角膜的程序的处理器或算法。所选择的模式被应用于患者，并且其适用性被评估为对该算法的评估反馈的结果，以生成应用于患者的精细输出设计。间隔重复该过程以检查持续近视进展，并在进一步测量后调整所选模态的设计。

10. 发明申请

US20100195093A1 CHARACTERIZATION OF OPTICAL SYSTEMS 审中-公开
标题翻译：光系统的表征
公开(公告)号：US20100195093A1
公开(公告)日：2010-08-05
申请号：US12527381
申请日：2008-02-14
申请人： Arthur Ho , Klaus Ehrmann
发明人： Arthur Ho , Klaus Ehrmann
IPC分类号： G01M11/02 , A61B3/10
CPC分类号： G01M11/0235 , A61B3/103 , A61B3/107 , G01M11/0257
摘要： An instrument and method is for characterizing the optical properties of an optical system, such as a lens, another optical device or the human eye, over an optical surface of the optical system. In one example, an incident beam is scanned over the surface of a lens to generate an emergent beam that is divided by a beam-splitter into two portions that are directed to respective two-dimensional detector arrays located at different optical distances from the lens. The detector arrays output the lateral coordinates of the points of incidence of the respective emergent beam portions so that the angle of emergent beam with respect to the optical axis or incident beam can be accurately determined. Determining the variation in the angle of the emergent beam over the surface of the lens allows many important optical characteristics of the lens to be characterized and mapped onto to the surface of the lens.
摘要翻译：仪器和方法用于在光学系统的光学表面上表征诸如透镜，另一光学装置或人眼的光学系统的光学特性。在一个示例中，入射光束被扫描在透镜的表面上，以产生由分束器分割成两个部分的出射光束，该两个部分被定向到与透镜不同的光学距离处的相应的二维检测器阵列。检测器阵列输出各个出射光束部分的入射点的横向坐标，使得可以准确地确定出射光束相对于光轴或入射光束的角度。确定出射光束在透镜表面上的角度的变化允许透镜的许多重要的光学特性被表征并映射到透镜的表面上。

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