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1. 发明专利

JP2017080428A 圧密化不要とした組織穿刺部閉鎖装置及び方法审中-公开
公开(公告)号：JP2017080428A
公开(公告)日：2017-05-18
申请号：JP2016234314
申请日：2016-12-01
申请人：セイントジュードメディカルプエルトリコエルエルシー , St Jude Medical Puerto Rico Llc , セイントジュードメディカルプエルトリコエルエルシー
发明人： RACHAEL A CRABB , THOMAS A SAVARD , IRWIN S WOLOSKY
IPC分类号： A61B17/03
CPC分类号： A61B17/0057 , A61B2017/00623 , A61B2017/00654 , A61B2017/00898 , A61B2017/0417 , A61B2017/0496
摘要：【課題】改良された、血管及び管腔用の処置及び装置を提供する。【解決手段】組織穿刺部閉鎖装置200は、キャリヤ管202と、縫合糸と、アンカー208と、封止パッド210とを備える。封止パッドは、キャリヤ管内に配置したときから、キャリヤ管内から取り出して組織壁穿刺部に隣接する後展開位置に配置するときまで、一定又はほぼ一定の形状を維持する。縫合糸は、封止パッドの形状を変化させることなく、アンカー及び封止パッドを組織壁に対して接触状態に保持する。【選択図】図9

2. 发明专利

JP2014158951A Tissue puncture closure system with retractable sheath 有权
标题翻译：组织枕头闭合系统
公开(公告)号：JP2014158951A
公开(公告)日：2014-09-04
申请号：JP2014090582
申请日：2014-04-24
申请人： St Jude Medical Puerto Rico Llc , セイントジュードメディカルプエルトリコエルエルシー
发明人： WHITE JOHN , FIEHLER WILLIAM , FORSBERG ANDREW T
IPC分类号： A61B17/12
CPC分类号： A61B17/0057 , A61B2017/00367 , A61B2017/00637 , A61B2017/00654 , A61B2017/00659
摘要： PROBLEM TO BE SOLVED: To provide methods and apparatus to seal a puncture or incision formed percutaneously in tissue to separate a living body into two internal portions.SOLUTION: Methods and apparatus 200 seal a puncture 218 or incision formed percutaneously in tissue to separate a living body into two internal portions, with an anchor 208, a sealing plug 210 and a filament 204 connecting the anchor and sealing plug. The methods and apparatus comprise a tamping tube 212 disposed adjacent to the sealing plug, and a free-floating automatic driving mechanism 630 for automatically tamping, with the tamping tube, the sealing plug toward a second end 207 of the apparatus when the apparatus is withdrawn from the puncture site, thereby providing automatic tamping and/or cinching of the sealing plug.
摘要翻译：要解决的问题：提供用于密封组织中经皮穿刺的穿刺或切口的方法和装置，以将生物体分离成两个内部部分。解决方案：方法和装置200密封穿刺组织中经皮形成的穿刺218或切口以分离生物主体分成两个内部部分，其中锚固件208，密封塞210和连接锚固件和密封塞的细丝204。该方法和装置包括邻近密封塞设置的捣实管212和一个自由浮动的自动驱动机构630，当自动浮动的自动驱动机构630被抽出时，用捣固管将密封塞朝向装置的第二端207自动捣实从穿刺部位，从而提供密封塞的自动捣固和/或收紧。

3. 发明专利

JP2012179374A Tissue puncture closure device with disengagable automatic tamping system 有权
标题翻译：具有可拆卸式自动清洗系统的组织式针式封闭装置
公开(公告)号：JP2012179374A
公开(公告)日：2012-09-20
申请号：JP2012097041
申请日：2012-04-20
申请人： St Jude Medical Puerto Rico Llc , セイントジュードメディカルプエルトリコエルエルシー
发明人： WHITE JOHN O , TERWEY RUSSELL D
IPC分类号： A61B17/12
CPC分类号： A61B17/0057 , A61B2017/00367 , A61B2017/00637 , A61B2017/00654 , A61B2017/00659
摘要： PROBLEM TO BE SOLVED: To provide a method and apparatus for sealing a puncture or incision formed percutaneously in tissue separating two internal portions of the body of a living being with an anchor, a sealing plug and a filament connecting the anchor and sealing plug.SOLUTION: A tissue puncture closure device for partial insertion into and sealing of an internal tissue wall puncture includes a filament extending from a first end of the closure device to a second end of the closure device, an anchor for insertion through the tissue wall puncture attached to the filament at the second end of the closure device, a sealing plug slidingly attached to the filament adjacent to the anchor, and a selectably disengagable automatic driving mechanism for automatically tamping or cinching the sealing plug toward the second end upon withdrawal of the closure device from the internal tissue wall puncture.
摘要翻译：要解决的问题：提供一种用于密封经皮形成的穿刺或切口的方法和装置，所述组织将活体的身体的两个内部部分与锚固件，密封塞和连接锚固件的细丝分开插头。解决方案：用于部分插入和密封内部组织壁穿刺的组织穿刺闭合装置包括从所述闭合装置的第一端延伸到所述闭合装置的第二端的细丝，用于插入所述组织的锚固件在封闭装置的第二端处附接到灯丝的壁穿刺，与锚固件相邻地滑动地附接到灯丝的密封塞，以及可选择地分离的自动驱动机构，用于在退出时自动地将密封塞朝向第二端紧固或收紧闭合装置从内部组织壁穿刺。版权所有（C）2012，JPO＆INPIT

4. 发明专利

JP2013173017A Extra-vascular sealing device and method 有权
标题翻译：超声波密封装置及方法
公开(公告)号：JP2013173017A
公开(公告)日：2013-09-05
申请号：JP2013100506
申请日：2013-05-10
申请人： St Jude Medical Puerto Rico Llc , セイントジュードメディカルプエルトリコエルエルシー
发明人： PIPENHAGEN CATHERINE A , GARDNER MELISSA K , FIEHLER WILLIAM , JACOBSEN JANET L , SCHORR GARY J , LIM JYUE BOON
IPC分类号： A61B17/12
CPC分类号： A61B17/0057 , A61B17/0467 , A61B2017/00637 , A61B2017/00654 , A61B2017/00898 , A61B2017/00986 , A61B2017/0475 , A61B2017/0496 , A61B2090/0811
摘要： PROBLEM TO BE SOLVED: To provide an improved vascular closure device or vascular sealing device that is easy to use, seals quickly and securely, and leaves no component in the blood vessel.SOLUTION: Various embodiments of a device are shown and disclosed for closing a vascular access puncture site following percutaneous diagnostic or therapeutic interventional procedures. In one embodiment, the closure device includes a vessel locating member 92, an anchor 112 and a sealing material 120. The closure device may be configured to deploy the anchor 112 and the sealing material 120 outside of a hole in a blood vessel to close the hole. The vessel locating member may be used to locate the blood vessel to ensure that the anchor and/or the sealing material are properly placed adjacent to the hole. The closure device may also include a tamper member configured to push or tamp the sealing material against the anchor. The closure device may also include a suture 118 that is used to hold the sealing material and the anchor together adjacent to the hole in the blood vessel.
摘要翻译：要解决的问题：为了提供易于使用的改进的血管闭合装置或血管密封装置，快速且牢固地密封，并且不在血管中留下组分。解决方案：显示和公开了装置的各种实施例以关闭经皮诊断或治疗介入手术后的血管通路穿刺部位。在一个实施例中，封闭装置包括容器定位构件92，锚固件112和密封材料120.闭合装置可以构造成将锚固体112和密封材料120展开在血管中的孔的外部以封闭孔。血管定位构件可以用于定位血管，以确保锚和/或密封材料适当地放置在孔附近。封闭装置还可以包括构造成将密封材料推压或夯在锚上的捣固构件。闭合装置还可以包括缝合线118，缝合线118用于将密封材料和锚固件保持在邻近血管中的孔的位置。

5. 发明申请

WO2014164009A2 OVAL VASCULAR CLOSURE DEVICE AND METHODS 审中-公开
标题翻译： OVAL血管闭塞装置及方法
公开(公告)号：WO2014164009A2
公开(公告)日：2014-10-09
申请号：PCT/US2014/019875
申请日：2014-03-03
申请人： ST. JUDE MEDICAL PUERTO RICO LLC
发明人： TEGELS, Zachary
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B2017/00654 , A61B2017/00659 , A61B2017/00672
摘要： A tissue puncture closure device having an anchor, a suture, a sealing plug, a compaction assembly, a carrier tube, and an insertion sheath. The suture is connected to the anchor at a distal end of the suture. The sealing plug is slidingly mounted to the suture and positioned proximal of the anchor. The compaction assembly is operable to compact the sealing plug toward the anchor. The carrier tube has the sealing plug positioned therein during delivery to a vessel puncture. The insertion sheath is insertable through the vessel puncture and configured to receive the carrier tube and anchor. At least the carrier tube has a cross-sectional shape with a greater width dimension than a height dimension.
摘要翻译：组织穿刺闭合装置，其具有锚固件，缝合线，密封塞，压实组件，承载管和插入护套。缝合线在缝合线的远端处连接到锚固件。密封塞滑动地安装到缝合线并且定位在锚的近侧。压实组件可操作以将密封塞压向锚固件。载体管在输送到容器穿刺期间具有定位在其中的密封塞。插入鞘可插入穿过血管穿刺并构造成接收载体管和锚。至少载体管具有比高度尺寸更大的宽度尺寸的横截面形状。

6. 发明申请

WO2014158747A1 LARGE BORE CLOSURE SECONDARY HEMOSTASIS BIOADHESIVE DELIVERY SYSTEMS AND METHODS 审中-公开
标题翻译：大型封闭式二次爆破生物传输系统及方法
公开(公告)号：WO2014158747A1
公开(公告)日：2014-10-02
申请号：PCT/US2014/019808
申请日：2014-03-03
申请人： ST. JUDE MEDICAL PUERTO RICO LLC
发明人： ESCOBAR, Martha , KRAMER, Scott , PARSONAGE, Edward E. , SMITH, Scott
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B17/00491 , A61B17/0469 , A61B17/0482 , A61B2017/00495 , A61B2017/0065 , A61B2017/00654 , A61B2017/00663 , A61B2017/0472 , A61B2017/06042
摘要： A vascular closure assembly includes a suture placement device and a sealant delivery device. The suture placement device is operable to position at least one suture across the puncture to form a primary seal of the puncture. The sealant delivery device includes a sealant delivery tube having a first lumen sized to receive the at least one suture, and a second lumen configured to deliver a volume of sealant to the puncture after forming the primary seal to create a secondary seal of the puncture. The sealant delivery device is slidable along the at least one suture to the puncture.
摘要翻译：血管闭合组件包括缝线放置装置和密封剂输送装置。缝合线放置装置可操作以将至少一条缝合线定位穿过穿刺以形成穿刺的主要密封。密封剂输送装置包括密封剂输送管，该密封剂输送管具有尺寸适于容纳至少一条缝合线的第一腔，以及构造成在形成主密封之后将一定体积的密封剂输送到穿刺以产生穿刺的次级密封的第二腔。密封剂输送装置可以沿着至少一个缝合线滑动到穿刺。

7. 发明申请

WO2014107179A1 VASCULAR CLOSURE DEVICE WITH IMPROVED SIDE LOADING 审中-公开
标题翻译：具有改进的侧面装载的血管闭合装置
公开(公告)号：WO2014107179A1
公开(公告)日：2014-07-10
申请号：PCT/US2013/029239
申请日：2013-03-06
申请人： ST. JUDE MEDICAL PUERTO RICO LLC
发明人： TEGELS, Zachary J.
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B2017/00623 , A61B2017/00654 , A61B2017/00898
摘要： A tissue puncture closure device includes a vessel locator (14) and a sealing plug delivery member (12). The vessel locator includes an expandable member (54). The sealing plug delivery member includes a carrier tube (16), a sealing plug (18), and a locking member (38). The carrier tube includes a distal end and a side opening (34), the side opening extending proximally from the distal end along at least a portion of a length of the carrier tube to provide lateral insertion of the vessel locator into an interior of the carrier tube. The sealing plug includes a lumen (46) and a slot (44) extending from a distal end to a proximal end of the sealing plug, wherein the slot provides lateral access of the vessel locator into the lumen. The locking member is operable to retain the vessel locator within the sealing plug delivery member.
摘要翻译：组织穿刺闭合装置包括容器定位器（14）和密封塞输送构件（12）。容器定位器包括可扩张构件（54）。密封塞输送构件包括载体管（16），密封塞（18）和锁定构件（38）。载体管包括远端和侧开口（34），所述侧开口沿着所述载体管的长度的至少一部分从所述远端向近侧延伸，以将所述容器定位器侧向插入所述载体的内部管。密封塞包括从密封塞的远端延伸到近端的内腔（46）和狭槽（44），其中所述狭槽提供血管定位器进入内腔的侧向进入。锁定构件可操作以将容器定位器保持在密封塞输送构件内。

8. 发明申请

WO2014107178A1 RAPID EXCHANGE TEMPORARY BLOOD FLOW CESSATION DEVICE FOR LARGE BORE CLOSURE 审中-公开
标题翻译：快速交换临时血液流量消除装置，用于大型封闭
公开(公告)号：WO2014107178A1
公开(公告)日：2014-07-10
申请号：PCT/US2013/029237
申请日：2013-03-06
申请人： ST. JUDE MEDICAL PUERTO RICO LLC
发明人： TEGELS, Zachary, J.
IPC分类号： A61B17/12
CPC分类号： A61M29/00 , A61B17/0057 , A61B17/0469 , A61B17/1204 , A61B17/12109 , A61B17/12136 , A61B2017/00663 , A61B2017/00867 , A61B2017/0472 , A61M29/02 , A61M2025/0183 , A61M2025/1052
摘要： A blood flow cessation device (12) includes a catheter (20), an expandable member (28), and a rapid exchange port (22). The catheter includes a distal end portion and a proximal end portion. The expandable member is positioned at the distal end portion and is selectively expandable to stop blood flow through a vessel. The rapid exchange port is formed in the catheter at a location proximal of the expandable member. The rapid exchange port is configured receive a guidewire (18) that passes through the distal end portion of the catheter to be positioned within the vessel.
摘要翻译：血液流动停止装置（12）包括导管（20），可膨胀构件（28）和快速交换口（22）。导管包括远端部分和近端部分。可扩张构件位于远端部分并且可选择性地可膨胀以阻止血液通过血管。快速交换口形成在可扩张构件的近侧位置处的导管中。快速交换口被配置为接收穿过导管的远端部分以定位在容器内的导丝（18）。

9. 发明申请

WO2014077878A1 DELIVERY TIP FOR EXTRAVASCULAR BIOADHESIVE CATHETER AND METHODS 审中-公开
标题翻译：用于超声波生物吸收管的方法和方法
公开(公告)号：WO2014077878A1
公开(公告)日：2014-05-22
申请号：PCT/US2013/027852
申请日：2013-02-27
申请人： ST. JUDE MEDICAL PUERTO RICO LLC
发明人： TERWEY, Russell, D. , TEGELS, Zachary, J. , PARSONAGE, Edward, E. , VIDLUND, Robert, M. , ESCOBAR, Martha
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B2017/0065 , A61B2017/22067
摘要： A vascular closure device includes an inflation balloon and a delivery tube. The delivery tube includes an inflation lumen configured to deliver inflation fluid to the inflation balloon, a sealant lumen configured to deliver a sealant to a vessel puncture, and a delivery tip in flow communication with the sealant lumen and having a plurality of outlet openings.
摘要翻译：血管闭合装置包括充气气囊和输送管。输送管包括构造成将膨胀流体输送到膨胀球囊的膨胀腔，构造成将密封剂递送到血管穿刺的密封腔，以及与密封剂腔流体连通并具有多个出口的输送尖端。

10. 发明申请

WO2014077877A1 BIOADHESIVE MIXING AND PREPARATION SYSTEMS AND METHODS USING TWO SYRINGES 审中-公开
标题翻译：生物混合和制备系统和使用两种注射剂的方法
公开(公告)号：WO2014077877A1
公开(公告)日：2014-05-22
申请号：PCT/US2013/027850
申请日：2013-02-27
申请人： ST. JUDE MEDICAL PUERTO RICO LLC
发明人： WHITE, Troy, T. , TEGELS, Zachary, J. , PARSONAGE, Edward, E. , TERWEY, Russell, D. , ESCOBAR, Martha , MCGLINCH, Timothy, M. , KAEFERLEIN, Bernhard
IPC分类号： A61B17/00 , A61J1/20
CPC分类号： A61B17/00491 , A61B17/0057 , A61B2017/00495 , A61B2017/0065 , A61B2017/22067
摘要： A bioadhesive mixing assembly (18) includes first (52) and second syringes (54) and an adapter (56). The first syringe includes first and second chambers (58, 60) holding a first sealant component (62) and an activator (64), respectively. The second syringe includes third and fourth chambers (70, 72)holding a second sealant component (74) and one of an activator (76) or a third sealant component, respectively. The adapter is mounted to the first syringe and includes first and second channels (100, 102) in flow communication with the first and second chambers, a first seal member (112)providing sealed access to the first and second channels, first and second needles (80, 82) connected in flow communication with the third and fourth chambers, and a second seal member (84) enclosing the first and second needles. Connecting the adapter to the second syringe punctures the first and second seal members with the first and second syringes to create flow communication between the first and third chambers and the second and fourth chambers.
摘要翻译：生物粘合剂混合组件（18）包括第一（52）和第二注射器（54）和适配器（56）。第一注射器包括分别保持第一密封剂组分（62）和活化剂（64）的第一和第二腔室（58,60）。第二注射器包括分别保持第二密封剂组分（74）和活化剂（76）或第三密封剂组分之一的第三和第四腔室（70,72）。适配器安装到第一注射器并且包括与第一和第二腔室流体连通的第一和第二通道（100,102），第一密封构件（112）提供对第一和第二通道的密封通路，第一和第二针头（80,82）与第三和第四室流动连通，以及封闭第一和第二针的第二密封构件（84）。将适配器连接到第二注射器用第一和第二注射器刺穿第一和第二密封构件，以在第一和第三腔室与第二和第四腔室之间产生流动连通。

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