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1. 发明申请

WO2004075230A2 METHOD AND APPARATUS FOR EFFICIENT TRANSFER OF IONS INTO A MASS SPECTROMETER 审中-公开
标题翻译：将离子有效转移到质谱仪中的方法和装置
公开(公告)号：WO2004075230A2
公开(公告)日：2004-09-02
申请号：PCT/US2004/003355
申请日：2004-02-19
申请人： SCIENCE & ENGINEERING SERVICES, INC. , DOROSHENKO, Vladimir, M. , LAIKO, Victor, V. , TAN, Phillip, V.
发明人： DOROSHENKO, Vladimir, M. , LAIKO, Victor, V. , TAN, Phillip, V.
IPC分类号： H01J
CPC分类号： H01J49/403
摘要： An apparatus and a method which produce a pulse of ions, generate a transient electric field correlated in time with a duration of the pulse of ions, receive the pulse of ions into the transient electric field, and collect the ions from an ion drift region of the transient electric field into a gas dynamic flow region of the mass analyzer. As such, an apparatus for transferring ions into a mass analyzer includes an ion source configured to generate the pulse of ions, a transient electric field device configured to receive the pulse of ions and generate the transient electric field, and an ion collector configured to collect the ions from the ion drift region and transfer the ions into the mass analyzer.
摘要翻译：产生离子脉冲的装置和方法产生时间上与离子脉冲持续时间相关的瞬时电场，将离子脉冲接收到瞬态电场中，并从离子漂移区域瞬态电场进入质量分析仪的气体动态流动区域。因此，用于将离子转移到质量分析器中的装置包括被配置为产生离子脉冲的离子源，被配置为接收离子脉冲并产生瞬态电场的瞬态电场装置，以及被配置为收集离子的离子收集器来自离子漂移区域的离子并将离子转移到质谱仪中。

2. 发明申请

WO1995033188A1 APPARATUS AND METHOD FOR TIME RESOLVED SPECTROSCOPY 审中-公开
标题翻译：用于时间分辨光谱的装置和方法
公开(公告)号：WO1995033188A1
公开(公告)日：1995-12-07
申请号：PCT/US1995006605
申请日：1995-05-30
申请人： RECON , SCIENCE & ENGINEERING SERVICES INC. , LEE, Hyo, Sang , NOTARI, Anthony
发明人： RECON , SCIENCE & ENGINEERING SERVICES INC.
IPC分类号： G01J03/28
CPC分类号： G01J3/2889 , G01J3/4406 , G01J3/453
摘要： A time resolved spectroscopy system and method are provided using digital processing tehcniques of a low power, continuous wave signal generated by a continuous wave light source, such as a cw laser. Time elapse is determined by measuring the time shift of the signal modulation sequence using the cross correlation of a return signal with the reference signal. The high resolution time delay is introduced at the start of each modulation cycle and the high resolution measurement is constructed by interlacing a data set based on the delay information. The high resolution TRS or fluorescence measurement is achieved by correlation calculation of the measured data and the reference code and deconvolving the autocorrelation function of the reference code.
摘要翻译：使用由连续波光源（例如cw激光器）产生的低功率连续波信号的数字处理技术来提供时间分辨光谱系统和方法。通过使用返回信号与参考信号的互相关来测量信号调制序列的时移来确定时间流逝。在每个调制周期开始时引入高分辨率时间延迟，并且通过基于延迟信息交织数据集来构造高分辨率测量。高分辨率TRS或荧光测量通过测量数据和参考代码的相关计算实现，并对参考代码的自相关函数进行去卷积。

3. 发明申请

WO2006083349A2 ENHANCED PORTABLE DIGITAL LIDAR SYSTEM 审中-公开
标题翻译：增强便携式数字激光系统
公开(公告)号：WO2006083349A2
公开(公告)日：2006-08-10
申请号：PCT/US2005/041786
申请日：2005-11-18
申请人： SCIENCE & ENGINEERING SERVICES, INC. , LEE, Hyo Sang , HWANG, In Heon , PRASAD, Coorg, R.
发明人： LEE, Hyo Sang , HWANG, In Heon , PRASAD, Coorg, R.
IPC分类号： F21V9/16
CPC分类号： G01S17/95 , G01N21/645 , G01N21/6486 , G01N2021/1793 , G01N2021/4709 , G01N2021/6476 , G01S7/481 , G01S7/4815 , G01S7/4817 , G01S17/88 , Y02A90/19
摘要： A system for detecting airborne agents. The system can include a laser source that provides laser pulses of at least two wavelengths, a transmitter that transmits the laser pulses, and a coupling mechanism configured to remotely couple the laser pulses between the laser source and the transmitter. The system can include a receiver receives both elastically backscattered signals from airborne agents and fluorescence signals from the airborne agents. The system can include a telescope both transmits a collimated laser beam of the laser pulse from the transmitter to a far field and receives the elastically backscattered signals and the fluorescence signals from the far field. The system can include a detection system having at least one of a backscatter optical detector that detects the elastically backscattered signals and one or more fluorescence optical detectors that detect the fluorescence signals in selected spectral band(s) from the airborne agents.
摘要翻译：一种用于检测空气传播剂的系统。该系统可以包括提供至少两个波长的激光脉冲的激光源，传递激光脉冲的发射器，以及配置成远程耦合激光源和发射器之间的激光脉冲的耦合机构。该系统可以包括一个接收器接收来自空气传播剂的弹性反向散射信号和来自空气传播剂的荧光信号。该系统可以包括望远镜将激光脉冲的准直激光束从发射器传输到远场，并且接收来自远场的弹性反向散射信号和荧光信号。该系统可以包括检测系统，该检测系统具有检测弹性反向散射信号的反向散射光学检测器和检测来自空气传播剂的所选频谱带中的荧光信号的一个或多个荧光光学检测器中的至少一个。

4. 发明公开

EP1595274A2 METHOD AND APPARATUS FOR EFFICIENT TRANSFER OF IONS INTO A MASS SPECTROMETER 审中-公开
标题翻译：方法和装置离子有效地转移到质谱仪
公开(公告)号：EP1595274A2
公开(公告)日：2005-11-16
申请号：EP04712799.8
申请日：2004-02-19
申请人： SCIENCE & ENGINEERING SERVICES INC.
发明人： DOROSHENKO, Vladimir, M. , LAIKO, Victor, V. , TAN, Phillip, V.
IPC分类号： H01J49/04
CPC分类号： H01J49/403
摘要： An apparatus and a method which produce a pulse of ions, generate a transient electric field correlated in time with a duration of the pulse of ions, receive the pulse of ions into the transient electric field, and collect the ions from an ion drift region of the transient electric field into a gas dynamic flow region of the mass analyzer. As such, an apparatus for transferring ions into a mass analyzer includes an ion source (20) configured to generate the pulse of ions, a transient electric field device configured to receive the pulse of ions and generate the transient electric field, and an ion collector configured to collect the ions from the ion drift region and transfer the ions into the mass analyzer (50).

5. 发明公开

EP0801727A1 APPARATUS AND METHOD FOR TIME RESOLVED SPECTROSCOPY 失效
标题翻译：用于时间分辨光谱的装置和方法
公开(公告)号：EP0801727A1
公开(公告)日：1997-10-22
申请号：EP95922892.0
申请日：1995-05-30
申请人： RECON , SCIENCE & ENGINEERING SERVICES INC.
发明人： LEE, Hyo, Sang , NOTARI, Anthony
IPC分类号： G01J3
CPC分类号： G01J3/2889 , G01J3/4406 , G01J3/453
摘要： A time resolved spectroscopy system and method are provided using digital processing tehcniques of a low power, continuous wave signal generated by a continuous wave light source, such as a cw laser. Time elapse is determined by measuring the time shift of the signal modulation sequence using the cross correlation of a return signal with the reference signal. The high resolution time delay is introduced at the start of each modulation cycle and the high resolution measurement is constructed by interlacing a data set based on the delay information. The high resolution TRS or fluorescence measurement is achieved by correlation calculation of the measured data and the reference code and deconvolving the autocorrelation function of the reference code.
摘要翻译：本发明提供了一种时间分辨光谱系统和方法，该系统和方法使用连续波光源（诸如CW激光器）产生的低功率连续波信号的数字处理技术。时间流逝通过使用返回信号与参考信号的互相关来测量信号调制序列的时移来确定。高分辨率时间延迟是在每个调制周期开始时引入的，并且高分辨率测量是通过基于延迟信息交错数据集来构建的。高分辨率TRS或荧光测量通过测量数据和参考代码的相关计算以及参考代码的自相关函数去卷积来实现。

6. 发明授权

US07965391B2 Airborne tunable mid-IR laser gas-correlation sensor 失效
公开(公告)号：US07965391B2
公开(公告)日：2011-06-21
申请号：US12644881
申请日：2009-12-22
申请人： Coorg Rangaswamy Prasad , Bo Lin , Hyo Sang Lee
发明人： Coorg Rangaswamy Prasad , Bo Lin , Hyo Sang Lee
IPC分类号： G01N21/00 , G01J5/00 , G01J5/02
CPC分类号： G01N21/3518 , G01N21/39 , G01S17/95 , Y02A90/19
摘要： A method and apparatus for measuring target gas concentrations in an atmosphere. The method and apparatus emit in the atmosphere a laser beam tuned to a molecular absorption line of a target gas, receive a reflected signal affected by gas absorption of the target gas in the atmosphere, divide and direct the received signal into a first optical path and a second optical path including in one of the paths a correlation gas cell filled with a predetermined concentration of the target gas, detect transmitted signals through the first optical path and the second optical path, and calculate a target gas concentration by comparing a first signal transmitted through the first optical path to a second signal transmitted through the second optical path. The apparatus includes a laser source tunable to a specific molecular absorption line of a target gas and configured to emit in the atmosphere a laser beam having a spectral bandwidth greater than a full width of the molecular absorption line of the target gas, a receiver configured to receive a reflected signal affected by gas absorption of the target gas in the atmosphere, and at least one detector configured to detect transmitted signals through the first optical path and the second optical path.

7. 发明授权

US07397029B2 Method and apparatus for ion fragmentation in mass spectrometry 失效
标题翻译：离子质谱分离方法和装置
公开(公告)号：US07397029B2
公开(公告)日：2008-07-08
申请号：US11620504
申请日：2007-01-05
申请人： Vadym D. Berkout , Vladimir M. Doroshenko
发明人： Vadym D. Berkout , Vladimir M. Doroshenko
IPC分类号： B01D59/44
CPC分类号： H01J49/0045
摘要： An apparatus for mass analyzing molecules includes a mass spectrometer configured to select precursor ions having a mass to charge ratio range, a metastable species generator configured to generate a metastable species for introduction into the mass spectrometer, and a mass detector configured to detect a mass of the product ions. The apparatus also includes interaction region in the mass spectrometer where the precursor ions are converted into product ions via interaction of the precursor ions with the metastable species. The mass spectrometer includes at least one of a three-dimensional ion trap, a linear ion trap, or an ion guide. The interaction region is located inside the three-dimensional ion trap, the linear trap, or the ion guide; and at least one of the precursor ions or at least one of the product ions are excited by an alternating electric field or collisionally activated to produce additional product ions.
摘要翻译：用于质量分析分子的装置包括：质谱仪，其被配置为选择具有质荷比范围的前体离子;构造成产生用于引入质谱仪的亚稳态物质的亚稳态物质发生器;以及质量检测器，产品离子。该装置还包括质谱仪中的相互作用区域，其中前体离子通过前体离子与亚稳态物质的相互作用转化成产物离子。质谱仪包括三维离子阱，线性离子阱或离子导体中的至少一种。相互作用区域位于三维离子阱，线性阱或离子导向器内; 并且至少一种前体离子或至少一种产物离子被交变电场激发或者被碰撞激活以产生另外的产物离子。

8. 发明申请

US20050079631A1 Method and apparatus for ionization of a sample at atmospheric pressure using a laser 审中-公开
标题翻译：使用激光在大气压下电离样品的方法和装置
公开(公告)号：US20050079631A1
公开(公告)日：2005-04-14
申请号：US10681198
申请日：2003-10-09
申请人： Victor Laiko , Vladimir Doroshenko
发明人： Victor Laiko , Vladimir Doroshenko
IPC分类号： G01N24/00 , H01J49/16
CPC分类号： H01J49/164 , H01J49/0031 , H01J49/0418 , Y10T436/24
摘要： A method for ionizing a sample at ambient pressure including providing ionization-assisting molecules on a surface of a substrate, placing sample molecules on the surface of the substrate, and irradiating at least one of the sample molecules and the ionization-assisting molecules to produce ions of the sample molecules at or near atmospheric pressure. Accordingly, the system for ionizing sample molecules at or near atmospheric pressure is disclosed.
摘要翻译：一种用于在环境压力下离子化样品的方法，包括在基底表面上提供电离辅助分子，将样品分子放置在基底表面上，并照射至少一个样品分子和电离辅助分子以产生离子的样品分子在大气压或接近大气压。因此，公开了在大气压或接近大气压下电离样品分子的系统。

9. 发明申请

US20020175294A1 Portable digital lidar system 失效
标题翻译：便携式数字激光雷达系统
公开(公告)号：US20020175294A1
公开(公告)日：2002-11-28
申请号：US09852782
申请日：2001-05-11
申请人： Science & Engineering Services, Inc.
发明人： Hyo Sang Lee , In Heon Hwang , Coorg R. Prasad
IPC分类号： G01N021/64
CPC分类号： G01N21/6486 , G01N21/3504 , G01N21/39 , G01N21/6402 , G01S7/4972 , G01S17/95 , Y02A90/19
摘要： A light detecting and ranging system and method for detecting airborne agents in which the system includes a laser which provides laser pulses of at least two wavelengths, a transmitter which transmits the laser pulses, a receiver which receives both elastically backscattered signals from airborne agents and fluorescence signals from the airborne agents, a common telescope which both focuses a laser beam transmission of the laser pulse from the transmitter to a far field and receives the elastically backscattered signals and the fluorescence signals from the far field, a digital detection system having at least one of a backscatter optical detector which detects the elastically backscattered signals and a fluorescence optical detector which detects the fluorescence signals from the airborne agents.
摘要翻译：一种用于检测空气传播剂的光检测和测距系统和方法，其中系统包括提供至少两个波长的激光脉冲的激光器，发射激光脉冲的发射器，接收来自空气传播剂的弹性反向散射信号的接收器和荧光来自空中传播媒介的信号，一种共同的望远镜，其将来自发射机的激光脉冲的激光束传输到远场并且接收来自远场的弹性反向散射信号和荧光信号，具有至少一个检测弹性反向散射信号的反向散射光检测器和检测来自空气传播剂的荧光信号的荧光光学检测器。

10. 发明申请

US20020121596A1 Capillary ion delivery device and method for mass spectroscopy 有权
标题翻译：毛细管离子传递装置和质谱法
公开(公告)号：US20020121596A1
公开(公告)日：2002-09-05
申请号：US09795108
申请日：2001-03-01
申请人： Science & Engineering Services, Inc.
发明人： Victor Laiko , Vladimir Doroshenko
IPC分类号： H01J049/00
CPC分类号： H01J49/0404
摘要： A system and method for mass spectrometry in which the system includes at least one ion source which produces ions, a mass spectrometer having an inlet orifice configured to accept the ions, and a capillary ion delivery device which detachably interfaces to the inlet orifice of the mass spectrometer. The method includes producing ions from the ion source, transporting the ions from the ion source to the inlet orifice of the mass spectrometer via the capillary ion delivery device, and mass analyzing the ions in the mass spectrometer.
摘要翻译：一种用于质谱的系统和方法，其中所述系统包括产生离子的至少一个离子源，具有被配置为接受离子的入口孔的质谱仪，以及可拆卸地与所述质量的入口孔接口的毛细管离子输送装置光谱仪该方法包括从离子源产生离子，通过毛细管离子传递装置将离子从离子源输送到质谱仪的入口孔，并质谱分析质谱仪中的离子。

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