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3. 发明专利

JP2012111959A Side-chain crystalline polymer for medical treatment 有权
标题翻译：用于医疗治疗的侧链晶体聚合物
公开(公告)号：JP2012111959A
公开(公告)日：2012-06-14
申请号：JP2012038904
申请日：2012-02-24
申请人： Reva Medical Inc , レヴァメディカル、インコーポレイテッドReva Medical, Inc.
发明人： BRANDOM DONALD K , MCGRATH JAMES E , ZELTINGER JOAN , SCHMID ERIC V , SCHULTZ ROBERT K
IPC分类号： C08F20/28 , A61F2/92 , A61K49/00 , A61K49/04 , A61L31/00 , C08F8/00
CPC分类号： A61L31/18 , A61F2/92 , A61K49/12 , A61K49/126 , A61K49/128 , A61L31/06 , C08F220/00 , C08G63/00 , C08G63/08
摘要： PROBLEM TO BE SOLVED: To provide a polymer including a main chain, a plurality of crystallizable side chains, and a plurality of heavy atoms attached to the polymer.SOLUTION: The polymer includes a main chain, a plurality of crystallizable side chains, and a plurality of heavy atoms attached to the polymer. The heavy atoms are present in an amount that is effective to render the polymer radiopaque. The polymer includes a recurring unit of a certain structure.
摘要翻译：要解决的问题：提供包含主链，多个可结晶侧链和连接到聚合物上的多个重原子的聚合物。聚合物包括主链，多个可结晶侧链和连接到聚合物上的多个重原子。重质原子以有效使聚合物不透射线的量存在。聚合物包括一定结构的重复单元。版权所有（C）2012，JPO＆INPIT

4. 发明专利

JP2008200530A Expandable stent with sliding and locking radial element 审中-公开
标题翻译：具有滑动和锁定径向元件的可扩展的支架
公开(公告)号：JP2008200530A
公开(公告)日：2008-09-04
申请号：JP2008140003
申请日：2008-05-28
申请人： Reva Medical Inc , リーヴァメディカルインコーポレイテッド
发明人： STEINKE THOMAS A , KOENIG DONALD H
IPC分类号： A61L31/00 , A61F2/00 , A61F2/92 , A61F2/94 , A61L31/16 , A61L33/10
CPC分类号： A61F2/92 , A61F2/07 , A61F2/91 , A61F2/915 , A61F2/93 , A61F2/94 , A61F2002/072 , A61F2002/075 , A61F2002/91533 , A61F2002/9155 , A61F2002/91591 , A61F2220/005 , A61F2220/0058 , A61F2250/0067 , A61F2250/0098 , A61L31/16 , A61L2300/416 , B33Y80/00
摘要： PROBLEM TO BE SOLVED: To provide a lumen support stent with a clear through-lumen for use in a body lumen. SOLUTION: The stent is formed from at least one series of sliding and locking radial elements and at least one ratcheting mechanism comprising an articulating element and a plurality of stops. The ratcheting mechanism permits one-way sliding of the radial elements from a collapsed diameter to an expanded diameter, but inhibits radial recoil from the expanded diameter. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供一种具有用于体腔的透明通管的管腔支架。解决方案：支架由至少一系列滑动和锁定的径向元件以及包括铰接元件和多个止动件的至少一个棘轮机构形成。棘轮机构允许径向元件从塌缩直径单向滑动到扩张直径，但是抑制从扩张直径的径向反冲。版权所有（C）2008，JPO＆INPIT

5. 发明申请

WO2014159337A1 REDUCED - PROFILE SLIDE AND LOCK STENT 审中-公开
标题翻译：减少 - 型材滑动和锁定
公开(公告)号：WO2014159337A1
公开(公告)日：2014-10-02
申请号：PCT/US2014/023080
申请日：2014-03-11
申请人： REVA MEDICAL, INC.
发明人： WEIER, Keith , HOWARD, Steven, C.
IPC分类号： A61F2/90
CPC分类号： A61F2/93 , A61F2230/0013 , A61F2230/0054
摘要： An expandable slide and lock stent comprises a tubular member that can be expanded from a collapsed state to an expanded state. The tubular member can comprise a reversing helical backbone and at least one rail member extending from the helical backbone in a circumferential direction. The backbone can have at least one engagement element that can be configured to receive a rail member to form the tubular member. In some embodiments, the reversing helical backbone can comprise a plurality of discrete segments having a variable profile and/or wave form. A plurality of regions of each backbone may have a recessed or "nesting" profile providing for a smaller overall stent profile in a compacted configuration, and improved stent retention as mounted on a balloon catheter.
摘要翻译：可扩张的滑动和锁定支架包括可以从折叠状态扩展到扩张状态的管状构件。管状构件可以包括反向螺旋主干和至少一个轨道构件，其沿圆周方向从螺旋主体延伸。主骨架可以具有至少一个接合元件，该接合元件可被构造成接收轨道构件以形成管状构件。在一些实施例中，反向螺旋骨架可以包括具有可变轮廓和/或波形的多个离散段。每个骨架的多个区域可以具有凹陷或“嵌套”轮廓，其提供压实构型中更小的总体支架轮廓，以及安装在气囊导管上的改进的支架保持。

6. 发明申请

WO2008100346A3 N-SUBSTITUTED MONOMERS AND POLYMERS 审中-公开
公开(公告)号：WO2008100346A3
公开(公告)日：2008-08-21
申请号：PCT/US2007/081566
申请日：2007-10-16
申请人： REVA MEDICAL, INC. , BALUCA, Earnest, G.
发明人： BALUCA, Earnest, G.
IPC分类号： A61L31/06 , A61L31/10 , A61L31/14 , A61L31/18 , C08G63/685 , C08G64/12 , C08G64/04 , C08G79/04 , C08G64/18
摘要： Described herein are N-substituted monomers and polymers, methods of making such monomers and polymers, and methods of using them in various applications, such as medical devices. In preferred embodiments, the medical device is a stent.

7. 发明申请

WO2007084444A3 SIDE-CHAIN CRYSTALLIZABLE POLYMERS FOR MEDICAL APPLICATIONS 审中-公开
标题翻译：用于医疗应用的侧链可结晶聚合物
公开(公告)号：WO2007084444A3
公开(公告)日：2008-07-17
申请号：PCT/US2007001011
申请日：2007-01-16
申请人： REVA MEDICAL INC , BRANDOM DONALD K , MCGRATH JAMES E , ZELTINGER JOAN , SCHMID ERIC V , SCHULTZ ROBERT K
发明人： BRANDOM DONALD K , MCGRATH JAMES E , ZELTINGER JOAN , SCHMID ERIC V , SCHULTZ ROBERT K
IPC分类号： A61L31/06 , A61F2/92 , A61L31/18
CPC分类号： A61L31/18 , A61F2/92 , A61K49/12 , A61K49/126 , A61K49/128 , A61L31/06 , C08F220/00 , C08G63/00 , C08G63/08
摘要： Side-chain crystallizable (SCC) polymers are useful in various medical applications. In certain applications, heavy atom containing side-chain crystallizable polymers (HACSCCP's) are particularly useful. An example of a HACSCCP is a polymer that comprises a main chain, a plurality of crystallizable side chains, and a plurality of heavy atoms attached to the polymer. In certain configurations, the heavy atoms are present in an amount that is effective to render the polymer radiopaque. A polymeric material that includes an HACSCCP may be fabricated into a medical device useful for at least partially occluding a body cavity. For example, such a medical device may be an embolotherapy product. A polymeric material that includes a SCC polymer may also be fabricated into other medical devices, such as stents.
摘要翻译：侧链可结晶（SCC）聚合物可用于各种医疗应用。在某些应用中，含重链原子的侧链可结晶聚合物（HACSCCP）特别有用。 HACSCCP的实例是包含主链，多个可结晶侧链和连接到聚合物上的多个重原子的聚合物。在某些构型中，重质原子以有效使聚合物不透射线的量存在。包括HACSCCP的聚合物材料可以制造成用于至少部分地封闭体腔的医疗装置。例如，这种医疗装置可以是电疗产品。包括SCC聚合物的聚合物材料也可制成其他医疗装置，例如支架。

8. 发明申请

WO2007114823A1 EMBOLIC PROSTHESIS FOR TREATMENT OF VASCULAR ANEURYSM 审中-公开
标题翻译：用于治疗血管瘤的手术治疗
公开(公告)号：WO2007114823A1
公开(公告)日：2007-10-11
申请号：PCT/US2006/013003
申请日：2006-04-06
申请人： REVA MEDICAL, INC. , PADILLA, Orlando , MORRIS, Andrew , NGUYEN, John , SCHMID, Eric, V. , BRANDOM, Don , MCGRATH, James, E.
发明人： PADILLA, Orlando , MORRIS, Andrew , NGUYEN, John , SCHMID, Eric, V. , BRANDOM, Don , MCGRATH, James, E.
IPC分类号： A61L24/06 , A61B17/12
CPC分类号： A61B17/12022 , A61B17/0467 , A61B17/12113 , A61B17/12136 , A61B17/12168 , A61B17/12172 , A61B17/12177 , A61B17/1219 , A61B2017/12054 , A61B2017/12081 , A61B2090/037 , A61K49/0442 , A61L24/001 , A61L24/0042 , A61L24/06 , A61L2430/36
摘要： The invention relates to an implantable embolic medical device comprising a non-erodible, erodible or biodegradable material. The device preferably comprises one or more longitudinal filament members of varying cross sectional shapes which may or may not be coiled to suit a particular clinical need. The embolic device is placed through lumens and cavities to reach areas in the body which require embolism to achieve a particular clinical objective.
摘要翻译：本发明涉及可植入栓塞医疗装置，其包括不可侵蚀，可侵蚀或可生物降解的材料。该装置优选地包括一个或多个变化的横截面形状的纵向长丝构件，其可以或可以不被卷起以适合特定的临床需要。栓塞装置通过腔和空腔放置以到达需要栓塞的身体中实现特定临床目标的区域。

9. 发明申请

WO2006020616A1 INHERENTLY RADIOPAQUE BIORESORBABLE POLYMERS FOR MULTIPLE USES 审中-公开
标题翻译：用于多种用途的绝对放射性可聚合聚合物
公开(公告)号：WO2006020616A1
公开(公告)日：2006-02-23
申请号：PCT/US2005/028228
申请日：2005-08-09
申请人： REVA MEDICAL, INC. , BRANDOM, Donald, K. , ZELTINGER, Joan
发明人： BRANDOM, Donald, K. , ZELTINGER, Joan
IPC分类号： C08G64/12
CPC分类号： C08G65/4006 , A61F2/91 , A61F2/915 , A61F2002/91533 , A61F2002/91591 , A61F2210/0004 , A61K49/0442 , A61L31/18 , B33Y70/00 , B33Y80/00 , C08G64/08 , C08G64/18
摘要： Preferred embodiments of the present invention relate to polymeric medical devices, such as stents. More particularly, the compositions disclosed herein comprise halogen-containing phenol moeities, that may be used for medical devices and other uses whereby bioresorbable and radiopaque and physicomechanical properties are desired.
摘要翻译：本发明的优选实施方案涉及聚合物医疗装置，例如支架。更具体地，本文公开的组合物包含含卤素的苯酚，其可用于医疗器械和其它需要生物可再吸收和不透射线和物理机械性能的用途。

10. 发明申请

WO2020032999A1 MULTI-BLOCK COPOLYMER COMPOSITIONS 审中-公开
公开(公告)号：WO2020032999A1
公开(公告)日：2020-02-13
申请号：PCT/US2019/016465
申请日：2019-02-04
申请人： REVA MEDICAL, INC.
发明人： KABALNOVA, Lioubov , BALUCA, Ernest, G. , EARLEY, Jessica
IPC分类号： C08L69/00 , A61L31/04 , A61L31/18 , C08G63/64 , A61L31/10 , C08G63/02 , C08G63/06
摘要： Methods of making multi-block copolymer that reduce the tendency for large phase domains to form provide copolymer compositions that are useful for various applications, including the manufacture of medical devices.

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