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1. 发明专利

ES2307625T3 DISPOSITIVO PARA LA REVASCULARIZACION DEL MIOCARDIO. 未知
公开(公告)号：ES2307625T3
公开(公告)日：2008-12-01
申请号：ES01948811
申请日：2001-06-28
申请人： RADIUS MEDICAL TECHNOLOGIES INC
发明人： DEMELLO RICHARD M , FINLAYSON MAUREEN A
IPC分类号： A61B18/14 , A61B17/00 , A61B18/12 , A61B19/00
摘要： Un dispositivo de tratamiento para el tejido corporal que tiene un conjunto (12) del extremo proximal que incluye un controlador (18) y un generador (22) de energía, el dispositivo de tratamiento caracterizado por: un conjunto (14) del extremo distal conectado al conjunto del extremo proximal a través de una parte (16) de cuerpo, incluyendo el conjunto del extremo distal una parte (30, 44) de calentamiento situada distal de una parte (40) no conductora, estando la parte de calentamiento conectada operativamente al controlador y generador de energía para recibir energía controlada desde el mismo, y la parte de calentamiento y la parte no conductora del conjunto del extremo distal están dimensionadas de forma que la parte de calentamiento, cuando se inserta en el miocardio de un corazón humano básicamente en vertical, está situada completamente entre el epicardio y el endocardio y en contacto con el tejido circundante, y la parte no conductora se extiende a través del epicardio o del endocardio, de forma que dicha energía suministrada a la parte de calentamiento reseca el tejido miocárdico circundante para formar una cavidad en él, y la parte no conductora evita la resección de la entrada a través del epicardio o endocardio para producir una entrada a la cavidad con un diámetro menor que la cavidad; y un conjunto (28) de inyección conectado de forma fluida mediante un lumen de la parte (16) de cuerpo al conjunto del extremo distal de forma que permite que el fluido se inyecte a través del conjunto del extremo distal y en la cavidad formada en el miocardio, caracterizado porque se proporciona más de un lumen que conduce al conjunto (14) del extremo distal para permitir que se inyecte un segundo fluido(s) (68) en la cavidad formada en el miocardio.

2. 发明专利

AT396657T 未知
公开(公告)号：AT396657T
公开(公告)日：2008-06-15
申请号：AT01948811
申请日：2001-06-28
申请人： RADIUS MEDICAL TECHNOLOGIES INC
发明人： DEMELLO RICHARD , FINLAYSON MAUREEN
IPC分类号： A61B18/14 , A61B17/00 , A61B18/12 , A61B19/00
摘要： A device and method for treating tissue at a treatment site. The device and method include supplying controlled energy to a heating portion of the device positioned within a tissue wall at the treatment site. The size of the heating portion and energy supplied provides for ablation of the tissue to form a cavity within the tissue wall without ablating the surfaces of the tissue wall. Treatment fluid can then be supplied through the device to the cavity to supplement growth of blood vessels or retard such growth at the treatment site. The device can also be used to create an injury zone at a treatment site without ablating tissue, wherein the injury zone can be injected with treatment fluid. The device and method has use anywhere within the body, especially in the regions of the heart.

3. 发明专利

DE60102075T2 未知
公开(公告)号：DE60102075T2
公开(公告)日：2004-09-16
申请号：DE60102075
申请日：2001-03-09
申请人： RADIUS MEDICAL TECHNOLOGIES INC
发明人： DEMELLO M , HEUSER R
IPC分类号： A61B17/22 , A61B17/32 , A61B19/00

4. 发明专利

ES2206574T3 未知
公开(公告)号：ES2206574T3
公开(公告)日：2004-05-16
申请号：ES96916806
申请日：1996-05-30
申请人： RADIUS MEDICAL TECHNOLOGIES INC
发明人： FINLAYSON MAUREEN
IPC分类号： A61B5/00 , A61M25/01 , A61M25/09
摘要： A guidewire includes a tapered core, an elongated non-radiopaque inner coil that is coincident with the core and extends over a distal portion of the core, and a radiopaque outer coil that fits over a distal end of the inner coil. The inner coil tapers between its proximal end and distal end, to form a tapered distal end section. The outer diameter of the proximal end of the inner coil is the same as the outer diameter of the proximal end of the core, before its first taper, and similarly, the outer diameter of the outer coil is the same as the outer diameter of the inner coil before its taper. Accordingly, the guidewire has an essentially uniform outer diameter over its entire length. A rounded tip that acts as a deformable buffer is formed where the distal ends of the two coils and the core join. The distal end of the core is preferably flattened to provide a formable end to the guidewire. A low friction coating may be added to the wire, to facilitate movement of the wire through the arteries.

5. 发明专利

DE60102075D1 未知
公开(公告)号：DE60102075D1
公开(公告)日：2004-03-25
申请号：DE60102075
申请日：2001-03-09
申请人： RADIUS MEDICAL TECHNOLOGIES INC
发明人： DEMELLO M , HEUSER R
IPC分类号： A61B17/22 , A61B17/32 , A61B19/00

6. 发明专利

AU2440702A Composite guidewire 未知
公开(公告)号：AU2440702A
公开(公告)日：2002-05-06
申请号：AU2440702
申请日：2001-10-18
申请人： RADIUS MEDICAL TECHNOLOGIES INC
发明人： DEMELLO RICHARD M
IPC分类号： A61B5/00 , A61M25/00 , A61M25/01 , A61M25/09
摘要： A composite guidewire includes a solid central core of super elastic material and one or more core overlays of non-super elastic material. A coupling tube fits over the proximal end of the core, and a coil, which may be radiopaque, fits over the distal end of the core and attaches to a distal end of the coupling tube. A flat safety wire that is positioned between the distal portion of the coupling tube and the core also attaches to the distal end of the tube. The safety wire extends the length of the coil and attaches to both the distal and the proximal ends of the coil. The guidewire's proximal end may be a non-super elastic core extension shaped at its distal end to overlap and mechanically inter-lock with a proximal end of the core and the coil and safety wire may extend beyond the distal end of the core.

7. 发明专利

AU5955896A Flexible guidewire with radiopaque outer coil and non-radiop aque inner coil 未知
公开(公告)号：AU5955896A
公开(公告)日：1996-12-18
申请号：AU5955896
申请日：1996-05-30
申请人： RADIUS MEDICAL TECHNOLOGIES INC
发明人： FINLAYSON MAUREEN
IPC分类号： A61B5/00 , A61M25/01 , A61M25/09
摘要： A guidewire includes a tapered core, an elongated non-radiopaque inner coil that is coincident with the core and extends over a distal portion of the core, and a radiopaque outer coil that fits over a distal end of the inner coil. The inner coil tapers between its proximal end and distal end, to form a tapered distal end section. The outer diameter of the proximal end of the inner coil is the same as the outer diameter of the proximal end of the core, before its first taper, and similarly, the outer diameter of the outer coil is the same as the outer diameter of the inner coil before its taper. Accordingly, the guidewire has an essentially uniform outer diameter over its entire length. A rounded tip that acts as a deformable buffer is formed where the distal ends of the two coils and the core join. The distal end of the core is preferably flattened to provide a formable end to the guidewire. A low friction coating may be added to the wire, to facilitate movement of the wire through the arteries.

8. 发明申请

WO2005087119A1 SMALL-DIAMETER SNARE 审中-公开
标题翻译：小直径鼻孔
公开(公告)号：WO2005087119A1
公开(公告)日：2005-09-22
申请号：PCT/US2005/007361
申请日：2005-03-07
申请人： RADIUS MEDICAL TECHNOLOGIES, INC. , DEMELLO, Richard, M. , FINLAYSON, Maureen, A. , FLIGHT, Bruce, W. , BURKHARDT, Jon
发明人： DEMELLO, Richard, M. , FINLAYSON, Maureen, A. , FLIGHT, Bruce, W. , BURKHARDT, Jon
IPC分类号： A61B17/32
CPC分类号： A61B17/32056 , A61B17/221 , A61B90/39 , A61B2017/22035 , A61B2017/22042 , A61B2017/22045 , A61B2017/2212 , A61B2017/2924
摘要： This invention provides a small diameter snare device consisting of a hollow, elongate, thin-walled polymer outer sheath. A single central core wire extends through the entire length of the sheath. The outer diameter of the core wire is sized close to the inner diameter of the sheath while allowing for axial sliding, in order to maximize the support to the body portion of the snare device. The distal end of the core wire has a tapered section of reduced diameter or cross section to provide a "guidewire-like" flexibility to the distal portion of the device. A second wire of about fifty percent of the inner diameter of the sheath is shaped to form a snare loop and the two ends are attached to the distal most portion of the central core wire via welding, soldering, or brazing. After assembly of the core and sheath, a second short, hollow tube is fitted over the proximal end of the central core and attached thereto to provide an actuating handle to slideably moue the central core within the sheath, thus exposing and retracting the snare loop from the open distal end of the sheath. The loop is typically circular or oval shaped and can also be multiplanar (for example, a twisted, figure eight shape) so as to increase the ability to ensnare and capture objects. The loop attachment to the core wire is facilitated and strengthened by a wrapped coupling coil formed typically of 0.001-inch platinum wire applied to secure the loop prior to soldering (brazing or other metal-flowing joining techniques), and through which solder flows to permanently secure the loop to the core wire.
摘要翻译：本发明提供一种由中空细长的薄壁聚合物外护套组成的小直径圈套装置。单个中心芯线延伸穿过护套的整个长度。芯线的外径尺寸接近护套的内径，同时允许轴向滑动，以便最大限度地提供对圈套装置的主体部分的支撑。芯线的远端具有减小直径或横截面的锥形部分，以向装置的远端部分提供“导丝状”柔性。护套内径大约百分之五十的第二根线被成形为形成一个圈套环，两端通过焊接，焊接或钎焊连接到中心芯线的最远端部分。在组装芯和护套之后，第二短的中空管装配在中心芯的近端上并附接到其上以提供致动手柄以可滑动地使护套内的中心芯移动，从而将圈套环从护套的开口远端。该环通常是圆形或椭圆形，并且也可以是多平面的（例如，扭曲的八字形状），以增加捕获和捕获物体的能力。通过一个通常用0.001英寸铂线形成的缠绕的耦合线圈来促进和加强与芯线的连接，以在焊接之前固定环（钎焊或其它金属流动接合技术），并且焊料通过其永久流动将环路固定到芯线。

9. 发明申请

WO0234324A3 COMPOSITE GUIDEWIRE 审中-公开
标题翻译：复合指南
公开(公告)号：WO0234324A3
公开(公告)日：2002-08-08
申请号：PCT/US0132443
申请日：2001-10-18
申请人： RADIUS MEDICAL TECHNOLOGIES INC
发明人： DEMELLO RICHARD M
IPC分类号： A61B5/00 , A61M25/00 , A61M25/01 , A61M25/09
CPC分类号： A61M25/09 , A61M25/09033 , A61M2025/09083 , A61M2025/09091 , A61M2025/09141
摘要： A composite guidewire includes a solid central core of super elastic material and one or more core overlays of non-super elastic material. More specifically, a coupling tube fits over the proximal end of the core, and a coil, which may be radiopaque, fits overthe distal end of the core and attaches to a distal end of the coupling tube. A flat safety wire that is positioned between the distal portion of the coupling tube and the core attaches to the distal end of the tube. The safety wire extends the length of the coil and attaches to both the distal and the proximal ends of the coil. The coil, the coupling tube and the safety wire, all being of non-super elastic materials, can all be attached to one another by soldering, brazing, welding or adhesives. The coupling tube may also be crimped at various locations along its length, to prevent relative rotational and axial movements of the tube and the superelastic core. An atraumatic tip, which fits over the end of the guidewire and attaches to the coil and the safety wire by brazing, welding or adhesives, may be included to provide a cushionat the distal end of the guidewire. The coil and the safety wire may extend beyond the distal end of the central core, such that the distal end of the guidewire can be shaped. The proximal end of the guidewire may also be formed with a non-super elastic core extension that is shaped at its distal end to overlap and mechanically inter-lock with a proximal end of the core. The coupling tube then extends partially over the non-super elastic core extension and partially over the super elastic core, with the proximal end of the coupling tube attached to the extension core by brazing, welding or adhesives. The safety wire attaches to the core extension and extends over the super elastic core to the distal end of the guidewire. The coil that fits over the distal end of the core attaches to both the safety wire and the coupling tube, as does a tip that forms the end of the guidewire.
摘要翻译：复合导丝包括超弹性材料的实心中心芯和非超弹性材料的一个或多个芯覆层。更具体地，耦合管装配在芯的近端上，并且可以是不透射线的线圈装配在芯的远端上并且附接到耦合管的远端。位于耦合管的远端部分和芯部之间的扁平安全线连接到管的远端。安全线延伸线圈的长度并且连接到线圈的远端和近端两端。线圈，联轴器和安全线均为非超弹性材料，均可通过焊接，钎焊，焊接或粘合剂相互连接。联接管也可以沿其长度卷曲在各个位置，以防止管和超弹性芯的相对旋转和轴向移动。可以包括安装在导丝端部并且通过钎焊，焊接或粘合剂附接到线圈和安全线的无创尖端，以在导丝的远端提供缓冲。线圈和安全线可以延伸超过中心芯的远端，使得导丝的远端可以成形。导丝的近端还可以形成有非超弹性芯延伸部，其在其远端处成形以与芯的近端重叠并机械地相互锁定。耦合管然后部分地延伸超过非弹性芯延伸部分并且部分地超过超弹性芯，耦合管的近端通过钎焊，焊接或粘合剂附接到延伸芯。安全线连接到芯部延伸部并且在超弹性芯上延伸到导丝的远端。装配在芯的远端上的线圈与形成导丝端部的尖端一样，附着在安全线和耦合管上。

10. 发明专利

AU7024101A Device and method for myocardial revascularization 未知
公开(公告)号：AU7024101A
公开(公告)日：2002-01-14
申请号：AU7024101
申请日：2001-06-28
申请人： RADIUS MEDICAL TECHNOLOGIES INC
发明人： DEMELLO RICHARD M , FINLAYSON MAUREEN A
IPC分类号： A61B17/00 , A61B18/14 , A61B19/00 , A61B18/12
摘要： A device and method for treating tissue at a treatment site. The device and method include supplying controlled energy to a heating portion of the device positioned within a tissue wall at the treatment site. The size of the heating portion and energy supplied provides for ablation of the tissue to form a cavity within the tissue wall without ablating the surfaces of the tissue wall. Treatment fluid can then be supplied through the device to the cavity to supplement growth of blood vessels or retard such growth at the treatment site. The device can also be used to create an injury zone at a treatment site without ablating tissue, wherein the injury zone can be injected with treatment fluid. The device and method has use anywhere within the body, especially in the regions of the heart.

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