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1. 发明专利

JP2014217755A 眼の画像処理の改良有权
标题翻译：眼睛图像处理改进
公开(公告)号：JP2014217755A
公开(公告)日：2014-11-20
申请号：JP2014094969
申请日：2014-05-02
申请人：オプトスピーエルシー , Optos Plc , オプトスピーエルシー
发明人： JANO VAN HEMERT , MICHAEL VERHOEK
IPC分类号： A61B3/14
CPC分类号： A61B3/0025 , A61B3/1005 , A61B3/1025 , A61B3/12 , A61B3/14 , G06T7/0012 , G06T7/64 , G06T2207/30041
摘要：【課題】眼の網膜の幾何学的測定値を判定する方法を提供する。【解決手段】眼の網膜の少なくとも一部の2次元表示を取得するステップ34と、網膜部分の3次元表示に網膜部分の2次元表示を変換する幾何学的再配置を抽出するステップ36と、網膜部分の2次元表示の1又はそれ以上の座標を使用して、2次元表示に関する網膜の取り込まれるべき幾何学的測定値を規定するステップ38と、幾何学的再配置を使用して網膜部分の3次元表示の相当する座標に、網膜部分の2次元表示の座標又は各座標を変換するステップ40と、網膜部分の3次元表示の座標又は各相当する座標を用いて、眼の網膜の幾何学的測定値を判定するステップ42と、を具える。【選択図】図2
摘要翻译：要解决的问题：提供一种用于确定眼睛视网膜的几何测量值的方法。解决方案：一种用于确定眼睛视网膜的几何测量值的方法，包括：获得至少一部分视网膜的二维显示眼睛的视网膜（34）; 导出将视网膜部分的二维显示转换成视网膜部分（36）的三维显示的几何重新映射; 使用所述视网膜部分的二维显示器的一个或多个坐标来指定在所述二维显示器（38）上取得的所述视网膜的几何测量值; 使用所述几何重新映射来将视网膜部分的二维显示器的坐标或相应坐标转换为视网膜部分（40）的三维显示器的等效坐标; 以及使用视网膜部分的三维显示的坐标或相应的等效坐标来确定眼睛（42）的视网膜的几何测量值。

2. 发明专利

JP2014121606A Improvement in ophthalmoscope 有权
标题翻译：眼科改善
公开(公告)号：JP2014121606A
公开(公告)日：2014-07-03
申请号：JP2013262075
申请日：2013-12-19
申请人： Optos Plc , オプトスピーエルシー
发明人： GONZALO MUYO , DEREK SWAN
IPC分类号： A61B3/12 , G01M11/02
CPC分类号： A61B3/12 , A61B3/0025 , A61B3/14
摘要： PROBLEM TO BE SOLVED: To provide a method of determining a correction for distortion in eye representations of an ophthalmoscope.SOLUTION: A method of determining a correction for distortion in eye representations of an ophthalmoscope comprises: (i) a step 30 of constructing an optical description of a system comprising the ophthalmoscope and a model eye; (ii) a step 32 of passing a ray through the system onto a surface of the model eye; (iii) a step 34 of calculating an actual measurement of the ray at the surface; (iv) a step 36 of determining a horizontal scanning angle and a vertical scanning angle of the system for the ray; (v) a step 38 of calculating an expected measurement of the ray at the surface using the horizontal scanning angle and vertical scanning angle of the system; (vi) a step 40 of repeating steps (ii) to (v) for a plurality of further rays; and (vii) a step 42 of comparing the actual measurements of the rays at the surface with corresponding expected measurements of the rays at the surface to determine the correction for distortion in eye representations of the ophthalmoscope.
摘要翻译：要解决的问题：提供一种确定检眼仪眼图中失真校正的方法。解决方案：一种确定检眼仪眼图中畸变校正的方法，包括：（i）构建光学眼镜的步骤30 描述包括检眼镜和模型眼睛的系统; （ii）使射线通过该系统到模型眼表面上的步骤32; （iii）计算表面上的射线的实际测量的步骤34; （iv）确定用于射线的系统的水平扫描角度和垂直扫描角度的步骤36; （v）使用系统的水平扫描角度和垂直扫描角度来计算表面上的射线的期望测量值的步骤38; （vi）对于多个另外的射线重复步骤（ii）至（v）的步骤40; 和（vii）将表面上的光线的实际测量与表面上的光线的相应预期测量值进行比较的步骤42，以确定检眼仪的眼睛表示中的失真校正。

3. 发明专利

JP2014217756A 検眼鏡の改良审中-公开
标题翻译：眼科改善
公开(公告)号：JP2014217756A
公开(公告)日：2014-11-20
申请号：JP2014094973
申请日：2014-05-02
申请人：オプトスピーエルシー , Optos Plc , オプトスピーエルシー
发明人： GONZALO MUYO , DEREK SWAN
IPC分类号： A61B3/10
CPC分类号： A61B3/1025 , A61B3/1225 , G02B27/0025 , G02B27/0031 , G02B27/0087
摘要：【課題】像の収差の矯正手段を有する検眼鏡を提供する。【解決手段】眼の網膜を走査するための走査レーザ検眼鏡であって、ビーム光を放射する光源と、走査リレー要素とを具えており、光源及び走査リレー要素が、眼の瞳孔点における見掛けの点光源から眼の網膜までのビーム光の2次元走査と、少なくともいくつかの走査リレー要素及び少なくともいくつかの走査リレー要素の収差の矯正を与えるよう選択される検眼鏡中の位置の収差の矯正を与えるよう規定される形状を有する静的収差矯正要素とを提供し、その位置が、眼の瞳孔点における見掛けの点光源から眼の網膜までのビーム光の伝達を維持する。【選択図】図2
摘要翻译：要解决的问题：提供一种具有图像像差校正装置的检眼镜。解决方案：提供一种用于扫描眼睛视网膜的扫描激光检眼镜，其包括发射光束的光源和扫描继电器元件。光源和扫描继电器元件提供从眼睛的瞳孔点处的视点光源转移到眼睛的视网膜的光束的二维扫描，以及具有形状被定义为提供至少一些扫描继电器元件的像差的校正，以及被选择用于提供至少一些扫描继电器元件的像差的校正的检眼镜内的位置。该位置保持在眼睛的瞳孔处的视点光源的光束到眼睛的视网膜的转移。

4. 发明申请

WO2021228395A1 RETINAL IMAGE PROCESSING 审中-公开
公开(公告)号：WO2021228395A1
公开(公告)日：2021-11-18
申请号：PCT/EP2020/063471
申请日：2020-05-14
申请人： OPTOS PLC
发明人： WAKEFORD, Peter Robert , PELLEGRINI, Enrico
IPC分类号： G06K9/00 , G06K9/62
摘要： An apparatus for generating an alert indicating an unreliability in a location of a landmark feature in a retinal image predicted by a machine learning algorithm, comprising: a receiver module which receives the predicted location; a probability indication determining module which uses the predicted location and a mixture model, which comprises a probability distribution of a landmark feature location and is based on determined locations of the landmark feature in retinal images having a plurality of retinal image classes, to determine, for each class, a respective probability indication indicating a probability that the retinal image belongs to the class; an outlier detector module which uses the probability indications to determine whether the retinal image is an outlier belonging to none of the classes; and an alert generator module which generates, when the retinal image belongs to none of the classes, an alert indicating unreliability of the predicted location.

5. 发明申请

WO2011135348A2 IMPROVEMENTS IN OR RELATING TO SCANNING OPHTHALMOSCOPES 审中-公开
标题翻译：改善或与扫描眼镜相关
公开(公告)号：WO2011135348A2
公开(公告)日：2011-11-03
申请号：PCT/GB2011/050818
申请日：2011-04-26
申请人： OPTOS PLC. , THOMSON, Martin , SWAN, Derek , GRAY, Dan , PEMBERTON, Stephen
发明人： THOMSON, Martin , SWAN, Derek , GRAY, Dan , PEMBERTON, Stephen
IPC分类号： A61B3/12
CPC分类号： A61B3/13 , A61B3/1025
摘要： The present invention provides a scanning ophthalmoscope for scanning the retina of an eye and a method of scanning the retina of an eye. The ophthalmoscope (10) comprises a source of collimated light (12), a first scanning element (14), a second scanning element (16) and a scan relay device (18) having two foci (18a, 18b). The source of collimated light (12), the first and second scanning elements (14, 16) and the scan relay device (18) combine to provide a two-dimensional collimated light scan (21) from an apparent point source (19). The scanning ophthalmoscope (10) further comprises a scan transfer device (20), wherein the scan transfer device (20) has two foci (20a, 20b) and at least one vertex (20c) and the apparent point source (19) is provided at a first focus (20a) of the scan transfer device (20) and an eye (22) is accommodated at a second focus (20b) of the scan transfer device (20), and wherein the scan transfer device (20) transfers the two-dimensional collimated light scan (21) from the apparent point source (19) into the eye (22). The two foci (18a, 18b) of the scan relay device (18) and the two foci (20a, 20b) of the scan transfer device (20) define a first plane and the two foci (20a, 20b) and the at least one vertex (20c) of the scan transfer device (20) define a second plane and wherein the first and second planes are substantially parallel.
摘要翻译：本发明提供了一种用于扫描眼睛的视网膜的扫描检眼镜和扫描眼睛的视网膜的方法。检眼镜（10）包括准直光源（12），第一扫描元件（14），第二扫描元件（16）和具有两个焦点（18a，18b）的扫描中继装置（18）。准直光源（12），第一和第二扫描元件（14,16）和扫描中继装置（18）组合以提供来自视点（19）的二维准直光扫描（21）。扫描检眼镜（10）还包括扫描传送装置（20），其中扫描传送装置（20）具有两个焦点（20a，20b）和至少一个顶点（20c），并且提供视点源（19）在扫描传送装置（20）的第一焦点（20a）和眼睛（22）被容纳在扫描传送装置（20）的第二焦点（20b）处，并且其中扫描传送装置（20）从视点（19）到眼睛（22）的二维准直光扫描（21）。扫描中继装置（18）的两个焦点（18a，18b）和扫描传送装置（20）的两个焦点（20a，20b）限定第一平面，并且两个焦点（20a，20b）至少扫描传送装置（20）的一个顶点（20c）限定第二平面，并且其中第一和第二平面基本平行。

6. 发明申请

WO2010125394A1 IMPROVEMENTS IN OR RELATING TO SCANNING OPHTHALMOSCOPES 审中-公开
标题翻译：改善或与扫描眼镜相关
公开(公告)号：WO2010125394A1
公开(公告)日：2010-11-04
申请号：PCT/GB2010/050713
申请日：2010-04-30
申请人： OPTOS PLC. , GRAY, Daniel, Curtis , WALL, Robert , ROBERTSON, Craig , CAIRNS, David
发明人： GRAY, Daniel, Curtis , WALL, Robert , ROBERTSON, Craig , CAIRNS, David
IPC分类号： A61B3/12
CPC分类号： A61B3/1025
摘要： The invention provides a scanning ophthalmoscope (10) for scanning the retina of an eye and method of operating the same. The scanning ophthalmoscope comprises a source of collimated light (12), a first scanning element (14) and a second scanning element (16). The source of collimated light (12) and the first and second scanning elements (14, 16) combine to provide a two-dimensional collimated light scan from an apparent point source. The scanning ophthalmoscope (10) further comprises a scan transfer device (20), wherein the scan transfer device (20) is a reflective element and has two foci and the apparent point source is provided at a first focus of the scan transfer device (20) and an eye (24) is accommodated at a second focus of the scan transfer device (20), and wherein the scan transfer device (20) transfers the two-dimensional collimated light scan from the apparent point source into the eye (24). The first and second scanning elements (14, 16) have operating parameters which are selected to control the direction of the two-dimensional collimated light scan from the apparent point source and/or adjust the dimensions of the two-dimensional collimated light scan from the apparent point source.
摘要翻译：本发明提供一种用于扫描眼睛视网膜的扫描检眼镜（10）及其操作方法。扫描检眼镜包括准直光源（12），第一扫描元件（14）和第二扫描元件（16）。准直光源（12）和第一和第二扫描元件（14,16）组合以提供来自视在点源的二维准直光扫描。扫描检眼镜（10）还包括扫描传送装置（20），其中扫描传送装置（20）是反射元件并且具有两个焦点，并且视点源设置在扫描传送装置（20）的第一焦点）和眼睛（24）容纳在扫描传送装置（20）的第二焦点处，并且其中扫描传送装置（20）将来自视点的二维准直光扫描传送到眼睛（24）。第一和第二扫描元件（14,16）具有操作参数，其被选择以控制来自表观点光源的二维准直光扫描的方向和/或调整二维准直光扫描的尺寸明点来源。

7. 发明申请

WO2008056110A3 IMPROVEMENTS IN OR RELATING TO RETINAL SCANNING 审中-公开
标题翻译：与视网膜扫描有关的改进或与之相关的改进
公开(公告)号：WO2008056110A3
公开(公告)日：2008-07-03
申请号：PCT/GB2007004185
申请日：2007-11-01
申请人： OPTOS PLC , ATKINSON ALASTAIR , MAZO CHRISTOPHE
发明人： ATKINSON ALASTAIR , MAZO CHRISTOPHE
IPC分类号： A61B3/12 , A61B5/00 , G06T15/20
CPC分类号： A61B3/1225 , A61B3/0025
摘要： A method and apparatus of producing a three-dimensional image of at least a part of the retina of an eye is provided. The method including obtaining a two-dimensional wide-field image of said part of said retina, determining a three-dimensional shape for said part of said retina and using the three-dimensional shape for said part of said retina to modify said two-dimensional image to produce a three-dimensional image of said part of said retina. The apparatus including an imaging system adapted to provide a two-dimensional wide-field image of said part of said retina, a three-dimensional shape determination module adapted to determine a three-dimensional shape for said part of said retina, and a two- dimensional image modification module adapted to modify said two- dimensional wide-field image of said part of said retina using said three- dimensional shape to produce a three-dimensional image of said part of said retina.
摘要翻译：提供了一种产生眼睛视网膜的至少一部分的三维图像的方法和装置。该方法包括获得所述视网膜的所述部分的二维宽视野图像，确定所述视网膜的所述部分的三维形状并且使用所述视网膜的所述部分的三维形状来修改所述二维图像以产生所述视网膜的所述部分的三维图像。该设备包括适于提供所述视网膜的所述部分的二维宽视野图像的成像系统，适于确定所述视网膜的所述部分的三维形状的三维形状确定模块，所述三维图像修改模块适于使用所述三维形状来修改所述视网膜的所述部分的所述二维宽视野图像以产生所述视网膜的所述部分的三维图像。

8. 发明申请

WO2008056110A2 IMPROVEMENTS IN OR RELATING TO RETINAL SCANNING 审中-公开
标题翻译：改进或相关的扫描
公开(公告)号：WO2008056110A2
公开(公告)日：2008-05-15
申请号：PCT/GB2007/004185
申请日：2007-11-01
申请人： OPTOS PLC , ATKINSON, Alastair , MAZO, Christophe
发明人： ATKINSON, Alastair , MAZO, Christophe
IPC分类号： A61B3/00
CPC分类号： A61B3/1225 , A61B3/0025
摘要： A method and apparatus of producing a three-dimensional image of at least a part of the retina of an eye is provided. The method including obtaining a two-dimensional wide-field image of said part of said retina, determining a three-dimensional shape for said part of said retina and using the three-dimensional shape for said part of said retina to modify said two-dimensional image to produce a three-dimensional image of said part of said retina. The apparatus including an imaging system adapted to provide a two-dimensional wide-field image of said part of said retina, a three-dimensional shape determination module adapted to determine a three-dimensional shape for said part of said retina, and a two- dimensional image modification module adapted to modify said two- dimensional wide-field image of said part of said retina using said three- dimensional shape to produce a three-dimensional image of said part of said retina.
摘要翻译：提供了生产眼睛的视网膜的至少一部分的三维图像的方法和装置。所述方法包括获得所述视网膜的所述部分的二维宽视场图像，确定所述视网膜的所述部分的三维形状并使用所述视网膜的所述部分的三维形状来修改所述二维以产生所述视网膜的所述部分的三维图像。该装置包括适于提供所述视网膜的所述部分的二维宽视野图像的成像系统，适于确定所述部分所述视网膜的三维形状的三维形状确定模块，所述三维图像修改模块适于使用所述三维形状修改所述视网膜的所述部分的所述二维宽视场图像，以产生所述视网膜的所述部分的三维图像。

9. 发明申请

WO2019034229A1 OPTICAL ELEMENT CONTROL 审中-公开
公开(公告)号：WO2019034229A1
公开(公告)日：2019-02-21
申请号：PCT/EP2017/070577
申请日：2017-08-14
申请人： OPTOS PLC
发明人： ANDERSON, Alan , ASHOK, Praveen , KASAI, Hiroshi , GORMAN, Alistair
IPC分类号： G02B3/14 , G02B26/00 , G02C7/08 , G09G3/34
摘要： There is provided an optical system comprising an optical element (10) responsive to an applied signal to vary an optical property of the optical element (10), the variation of the optical property with the applied signal exhibiting hysteresis in a first range of values of the signal, and no hysteresis in at least one second range of values of the signal. The optical system further comprises a memory storing data representative of a variation of the optical property with either increasing values of the signal or decreasing values of the signal, and a controller configured to control the optical property of the optical element (10) by generating a control signal based on the stored data and applying the generated control signal to the optical element. In a case where the memory stores data representative of the variation of the optical property with increasing values of the signal, the controller is configured to use the stored data to change the value of the optical property from an initial value corresponding to a first value of the signal, to a subsequent value corresponding to a second value of the signal that is smaller than the first value of the signal, by setting the value of the control signal to a third value that is within the second range of values, and subsequently increasing the value of the control signal from the third value to the second value. Alternatively, in a case where the memory stores data representative of the variation of the optical property with decreasing values of the signal, the controller is configured to use the stored data to change the value of the optical property from an initial value corresponding to a first value of the signal, to a subsequent value corresponding to a second value of the signal that is greater than the first value of the signal, by setting the value of the control signal to a third value that is within the second range of values, and subsequently decreasing the value of the control signal from the third value to the second value.

10. 发明申请

WO2018069346A1 OPHTHALMIC DEVICE 审中-公开
标题翻译：眼科装置
公开(公告)号：WO2018069346A1
公开(公告)日：2018-04-19
申请号：PCT/EP2017/075852
申请日：2017-10-10
申请人： OPTOS PLC , NIKON CORPORATION
发明人： MUYO, Gonzalo , GORMAN, Alistair , ISHIDA, Makoto
IPC分类号： A61B3/10 , A61B3/12 , A61B3/15 , G06K9/00 , G06T7/00 , A61B3/00
CPC分类号： A61B3/0091 , A61B3/102 , A61B3/1025 , G06K9/0061 , G06T7/0012
摘要： The present invention provides an ophthalmic device comprising a light source (82; 84) arranged to emit a fixation target light, and a reflecting face (68A) arranged to reflect scanning light emitted by an emission section and to scan the scanning light in a specific direction by changing orientation, the emission section being a source of the scanning light that is different to the light source. The ophthalmic device further comprises a concave mirror face (70A) disposed such that the scanning light reflected by the reflecting face (68A) is incident on the ocular fundus of a subject's eye (38) when the subject's eye is placed at a focal point of the concave mirror (70) during use of the ophthalmic device, and is arranged such that, when the subject's eye (38) is placed at the focal point of the concave mirror (70) during use of the ophthalmic device and when the light source (82; 84) emits the fixation target light, the fixation target light and the scanning light are simultaneously incident on the ocular fundus via different optical paths both propagating via the concave mirror face (70A) and the focal point, the target fixation light following a predetermined optical path for fixing the gaze of the subject's eye (38).
摘要翻译：本发明提供一种眼科装置，其包括布置成发射固视目标光的光源（82; 84）和布置成反射由发射部发射的扫描光的反射面（68A），以及以通过改变取向在特定方向上扫描扫描光，发射部分是与光源不同的扫描光源。所述眼科装置还包括凹面镜面（70A），所述凹面镜面（70A）被布置成使得当被检眼位于患者的眼睛（38A）的焦点处时被所述反射面（68A）反射的扫描光入射到被检眼（38）的眼底上所述凹镜（70）在使用所述眼科装置期间布置成使得当在所述眼科装置的使用期间将所述对象的眼睛（38）放置在所述凹面镜（70）的焦点处时并且当所述光源（82,84）发射固视目标光，固视目标光和扫描光通过经由凹面镜面（70A）和焦点传播的不同光路同时入射到眼底上，目标固定光跟随用于固定对象眼睛（38）的凝视的预定光路。

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