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1. 发明申请

WO2010042557A3 METHOD AND APPARATUS FOR CORRECTIVE SECONDARY SACCADES ANALYSIS WITH VIDEO OCULOGRAPHY SYSTEM 审中-公开
标题翻译：用于视频彩色图像系统的校正二次分析的方法和装置
公开(公告)号：WO2010042557A3
公开(公告)日：2010-08-05
申请号：PCT/US2009059749
申请日：2009-10-06
申请人： NEURO KINETICS INC , KIDERMAN ALEXANDER D , EYDELMAN YAKOV
发明人： KIDERMAN ALEXANDER D , EYDELMAN YAKOV
IPC分类号： A61B3/00
CPC分类号： A61B3/113 , A61B3/0025 , A61B3/0041 , A61B3/0091 , A61B3/145 , A61B5/4076 , A61B5/4863 , A61B5/6814 , G03B2213/025
摘要： A video oculography system for calculation and display of Corrective Secondary Saccades Analysis is disclosed. A method for Objective Diagnostics of at least one of traumatic brain injury, lnternuclear Opthalmopligia, Ocular Lateral Pulsion, Progressive Supernuclear Palsy And Glissades comprises the steps of using a VOG system to calculate corrective saccades. The video oculography based system for the subject is configured to collect eye images of the patient in excess of 60 hz and configured to resolve eye movements smaller than at least 3 degrees of motion. The video oculography based system collects eye movement data wherein at least one fixation target is presented to the subject in a defined position configured to yield a voluntary saccadic eye response from at least one eye of the patient. The latency, amplitude, accuracy and velocity of each respective corrective saccade and totals latency and accuracy is calculated.
摘要翻译：公开了一种用于计算和显示纠正次级骶骨分析的视频眼图系统。目的诊断创伤性脑损伤，核型眼睑炎，眼外侧脉冲，进行性超核麻痹和果皮中的至少一种的方法包括使用VOG系统计算校正扫视的步骤。用于受试者的视频基于眼图的系统被配置为收集超过60hz的患者的眼睛图像并且被配置为解决小于至少3度运动的眼睛运动。基于视频基于眼睛的系统收集眼睛运动数据，其中至少一个固定目标在被配置为从患者的至少一只眼睛产生自愿的眼睛反应的限定位置呈现给受试者。计算每个相应校正扫视的延迟，幅度，精度和速度以及总和等待时间和准确度。

2. 发明申请

WO2017147141A1 OBJECTIVE TESTING OF VERGENCE DYSFUNCTION FOR DIAGNOSIS AND VERGENCE RECOVERY CONVALESCENCE USING DYNAMIC VERGENCE TESTING PLATFORM INCLUDING 3D HEAD MOUNTED DISPLAY SYSTEM WITH INTEGRATED EYE TRACKING TECHNOLOGY 审中-公开
标题翻译：使用动态辐照测试平台进行诊断和回声恢复相容性的趋势失常的目标测试，包括带集成眼睛追踪技术的3D头戴式显示系统
公开(公告)号：WO2017147141A1
公开(公告)日：2017-08-31
申请号：PCT/US2017/018862
申请日：2017-02-22
申请人： NEURO KINETICS, INC.
发明人： KIDERMAN, Alexander, D. , ASHMORE, Robin, C.
IPC分类号： A61B3/113
CPC分类号： A61B3/113
摘要： An objective testing of vergance dysfunction comprising the steps of: providing a head mounted goggle based stimulus generating eye tracking unit to the subject; presenting visual stimulus to the subject, wherein the visual stimulus is in the head mounted goggle based system and forms the optical target stimulus for at least one vergence test; obtaining objective physiologic response of the subject from the head mounted goggle unit based upon each of the visual stimulus presented to the subject in each test; and using the objective physiologic responses to diagnose the presence of vergance dysfunction. On objective portable head mounted goggle based stimulus generating eye tracking unit for vergance testing is discloses as is a method of method of vergance recovery convalescence.
摘要翻译：对优雅功能障碍的客观测试包括以下步骤：向所述对象提供基于头戴式护目镜的刺激产生眼睛跟踪单元; 向所述对象呈现视觉刺激，其中所述视觉刺激在所述头戴式护目镜系统中并形成用于至少一个聚散度测试的所述光学目标刺激; 基于每次测试中呈现给对象的每种视觉刺激，从头戴式护目镜单元获得对象的客观生理反应; 并使用客观生理反应来诊断优雅功能障碍的存在。在客观便携式头戴式护目镜基础刺激产生用于优雅测试的眼睛跟踪单元被公开为恢复恢复期的方法。

3. 发明申请

WO2010042557A2 METHOD AND APPARATUS FOR CORRECTIVE SECONDARY SACCADES ANALYSIS WITH VIDEO OCULOGRAPHY SYSTEM 审中-公开
标题翻译：用视频透视系统进行校正二次层析分析的方法和装置
公开(公告)号：WO2010042557A2
公开(公告)日：2010-04-15
申请号：PCT/US2009/059749
申请日：2009-10-06
申请人： NEURO KINETICS, INC. , KIDERMAN, Alexander, D. , EYDELMAN, Yakov
发明人： KIDERMAN, Alexander, D. , EYDELMAN, Yakov
IPC分类号： A61B3/00
CPC分类号： A61B3/113 , A61B3/0025 , A61B3/0041 , A61B3/0091 , A61B3/145 , A61B5/4076 , A61B5/4863 , A61B5/6814 , G03B2213/025
摘要： A video oculography system for calculation and display of Corrective Secondary Saccades Analysis is disclosed. A method for Objective Diagnostics of at least one of traumatic brain injury, lnternuclear Opthalmopligia, Ocular Lateral Pulsion, Progressive Supernuclear Palsy And Glissades comprises the steps of using a VOG system to calculate corrective saccades. The video oculography based system for the subject is configured to collect eye images of the patient in excess of 60 hz and configured to resolve eye movements smaller than at least 3 degrees of motion. The video oculography based system collects eye movement data wherein at least one fixation target is presented to the subject in a defined position configured to yield a voluntary saccadic eye response from at least one eye of the patient. The latency, amplitude, accuracy and velocity of each respective corrective saccade and totals latency and accuracy is calculated.
摘要翻译：公开了一种用于计算和显示矫正二次神经分析的视频眼球系统。目的诊断至少一种创伤性脑损伤，核内光学眼压，眼外侧痉挛，进行性超核麻痹和发怒的方法包括使用VOG系统计算矫正眼跳的步骤。用于受试者的基于视频眼动的系统被配置为收集超过60Hz的患者的眼睛图像并且被配置为解析小于至少3度运动的眼睛运动。基于视频眼动的系统收集眼睛运动数据，其中至少一个固定目标在限定的位置呈现给对象，该限定的位置被配置为产生来自患者的至少一只眼睛的自愿扫视眼响应。计算每次各自校正扫视的潜伏时间，幅度，准确度和速度以及总计延迟和准确度。

4. 发明申请

US20100092049A1 Method of Precision Eye-Tracking Through Use of Iris Edge Based Landmarks in Eye Geometry 有权
标题翻译：通过在眼睛几何中使用基于光圈边缘的地标进行精确眼动跟踪的方法
公开(公告)号：US20100092049A1
公开(公告)日：2010-04-15
申请号：US12420111
申请日：2009-04-08
申请人： John Howison Schroeder , Alexander D. Kiderman
发明人： John Howison Schroeder , Alexander D. Kiderman
IPC分类号： G06K9/00 , A61B3/113
CPC分类号： A61B3/113 , G06K9/00604
摘要： In the field of eye tracking, greater accuracy or resolution in monitoring movement of the eye can be gained by digitizing the eye, and tracking the movement of a landmark with fixed size and a fixed location relative to the eye's local coordinate system. The edge of the iris can be used as such a fixed landmark. Through the location and or establishment of at least a portion of the outer edge of the iris and/or an iris center point, both large and small scale eye movements, including but not limited to micro-tremors, can be traced with a higher degree of accuracy. This will aid in the diagnosis of diseases, assessing state of consciousness, and defining brainstem death.
摘要翻译：在眼睛跟踪领域，可以通过数字化眼睛和跟踪具有固定尺寸和相对于眼睛的局部坐标系的固定位置的地标的移动来获得监视眼睛运动的更高精度或分辨率。虹膜的边缘可以用作固定的地标。通过虹膜的外边缘和/或虹膜中心点的至少一部分的位置和/或建立，可以以更高的程度来追踪包括但不限于微震的大小尺度眼睛运动的准确性。这将有助于诊断疾病，评估意识状态和确定脑干死亡。

5. 发明授权

US07520614B2 Portable video oculography with region of interest image processing 有权
标题翻译：具有感兴趣区域图像处理的便携式视频眼图
公开(公告)号：US07520614B2
公开(公告)日：2009-04-21
申请号：US11926806
申请日：2007-10-29
申请人： Thomas C. Joos , Alexander D Kiderman , John Howison Schroeder , Floris L. Wuyts , Steven T Moore , Hamish G MacDougall
发明人： Thomas C. Joos , Alexander D Kiderman , John Howison Schroeder , Floris L. Wuyts , Steven T Moore , Hamish G MacDougall
IPC分类号： A61B3/14 , A61B3/10
CPC分类号： A61B3/113
摘要： A goggle based light-weight VOG system includes at least one digital camera connected to and powered by a laptop computer through a firewire connection and allows for region of interest image processing. An EOG system may be incorporated directly into a goggle base. The digital camera may digitally center the pupil in both the X and Y directions. A calibration mechanism may be incorporated onto the goggle base. The VOG system may track and record head position and goggle slippage. An animated eye display may provide data in a more meaningful fashion. The VOG system may be a modular design whereby the same goggle frame or base is used to build a variety of digital camera VOG systems.
摘要翻译：基于护目镜的轻量级VOG系统包括通过火线连接连接到膝上型计算机并由其供电的至少一个数字照相机，并且允许感兴趣的图像处理区域。 EOG系统可以直接并入护目镜基座。数码相机可以在X和Y方向上数字地居中瞳孔。校准机构可以结合到护目镜基座上。 VOG系统可以跟踪和记录头部位置和护目镜滑移。动画眼睛显示器可以以更有意义的方式提供数据。 VOG系统可以是模块化设计，其中相同的护目镜框架或基座用于构建各种数字照相机VOG系统。

6. 发明申请

US20080278685A1 PORTABLE MODULAR VIDEO OCULOGRAPHY SYSTEM AND VIDEO OCCULOGRAPHY SYSTEM WITH HEAD POSITION SENSOR AND VIDEO OCCULOGRAPHY SYSTEM WITH ANIMATED EYE DISPLAY 有权
标题翻译：便携式模块化视频摄影系统和视频摄影系统，具有头位置传感器和视频摄影系统，具有动画眼睛显示
公开(公告)号：US20080278685A1
公开(公告)日：2008-11-13
申请号：US11927984
申请日：2007-10-30
申请人： Hamish G. MacDougall , Alexander D. Kiderman , John Howison Schroeder , Thomas C. Joos , Floris L. Wuyts , Steven T. Moore
发明人： Hamish G. MacDougall , Alexander D. Kiderman , John Howison Schroeder , Thomas C. Joos , Floris L. Wuyts , Steven T. Moore
IPC分类号： A61B3/113 , A61B3/14
CPC分类号： A61B3/113
摘要： A goggle based light-weight VOG system includes at least one digital camera connected to and powered by a laptop computer through a firewire connection and allows for region of interest image processing. The VOG system is a modular design whereby the same goggle frame or base is used to build a variety of digital camera VOG systems. The VOG system may track and record head position and goggle slippage. An animated eye display may provide data in a more meaningful fashion. An EOG system may be incorporated directly into a goggle base. The digital camera may digitally center the pupil in both the X and Y directions. A calibration mechanism may be incorporated onto the goggle base. The VOG system may be a modular design whereby the same goggle frame or base is used to build a variety of digital camera VOG systems.
摘要翻译：基于护目镜的轻量级VOG系统包括通过火线连接连接到膝上型计算机并由其供电的至少一个数字照相机，并且允许感兴趣的图像处理区域。 VOG系统是一种模块化设计，使用相同的护目镜框架或底座来构建各种数码相机VOG系统。 VOG系统可以跟踪和记录头部位置和护目镜滑移。动画眼睛显示器可以以更有意义的方式提供数据。 EOG系统可以直接并入护目镜基座。数码相机可以在X和Y方向上数字地居中瞳孔。校准机构可以结合到护目镜基座上。 VOG系统可以是模块化设计，其中相同的护目镜框架或基座用于构建各种数字照相机VOG系统。

7. 发明申请

US20080049187A1 PORTABLE VIDEO OCULOGRAPHY WITH REGION OF INTEREST IMAGE PROCESSING 有权
标题翻译：具有利益影响区域的便携式视频摄影
公开(公告)号：US20080049187A1
公开(公告)日：2008-02-28
申请号：US11926806
申请日：2007-10-29
申请人： Thomas Joos , Alexander Kiderman , John Schroeder , Floris Wuyts , Steven Moore , Hamish MacDougall
发明人： Thomas Joos , Alexander Kiderman , John Schroeder , Floris Wuyts , Steven Moore , Hamish MacDougall
IPC分类号： A61B3/14
CPC分类号： A61B3/113
摘要： A goggle based light-weight VOG system includes at least one digital camera connected to and powered by a laptop computer through a firewire connection and allows for region of interest image processing. An EOG system may be incorporated directly into a goggle base. The digital camera may digitally center the pupil in both the X and Y directions. A calibration mechanism may be incorporated onto the goggle base. The VOG system may track and record head position and goggle slippage. An animated eye display may provide data in a more meaningful fashion. The VOG system may be a modular design whereby the same goggle frame or base is used to build a variety of digital camera VOG systems.
摘要翻译：基于护目镜的轻量级VOG系统包括通过火线连接连接到膝上型计算机并由其供电的至少一个数字照相机，并且允许感兴趣的图像处理区域。 EOG系统可以直接并入护目镜基座。数码相机可以在X和Y方向上数字地居中瞳孔。校准机构可以结合到护目镜基座上。 VOG系统可以跟踪和记录头部位置和护目镜滑移。动画眼睛显示器可以以更有意义的方式提供数据。 VOG系统可以是模块化设计，其中相同的护目镜框架或基座用于构建各种数字照相机VOG系统。

8. 发明申请

US20070121068A1 Portable video oculography system with integral light stimulus system 有权
标题翻译：具有整体光刺激系统的便携式视频眼图系统
公开(公告)号：US20070121068A1
公开(公告)日：2007-05-31
申请号：US11549185
申请日：2006-10-13
申请人： Hamish MacDougall , Alexander Kiderman , John Schroeder , Thomas Joos , Floris Wuyts , Steven Moore
发明人： Hamish MacDougall , Alexander Kiderman , John Schroeder , Thomas Joos , Floris Wuyts , Steven Moore
IPC分类号： A61B3/10
CPC分类号： A61B3/113
摘要： A goggle based light-weight VOG system includes at least one digital camera connected to and powered by a laptop computer through a firewire connection together with an integral visual light stimulus source. The digital camera may digitally center the pupil in both the X and Y directions. A calibration mechanism may be incorporated onto the goggle base. An EOG system may also be incorporated directly into the goggle. The VOG system may track and record 3-D movement of the eye, track pupil dilation, head position and goggle slippage. An animated eye display provides data in a more meaningful fashion. The VOG system is a modular design whereby the same goggle frame or base is used to build a variety of digital camera VOG systems.
摘要翻译：基于护目镜的轻量级VOG系统包括至少一个连接到膝上型计算机并通过火线连接并与整体的视觉光刺激源一起的数字照相机。数码相机可以在X和Y方向上数字地居中瞳孔。校准机构可以结合到护目镜基座上。 EOG系统也可以直接并入护目镜中。 VOG系统可以跟踪和记录眼睛的三维运动，跟踪瞳孔扩张，头部位置和护目镜滑移。动画眼睛显示器以更有意义的方式提供数据。 VOG系统是一种模块化设计，使用相同的护目镜框架或底座来构建各种数码相机VOG系统。

9. 发明授权

US11419493B2 Method and apparatus for mTBI diagnosis implementing eye movement and pupil movement analysis in objective vergence testing 有权
公开(公告)号：US11419493B2
公开(公告)日：2022-08-23
申请号：US15897137
申请日：2018-02-14
申请人： Neuro Kinetics, Inc. , University of Pittsburgh—Of the Commonwealth System of Higher Education , University of Miami
发明人： Carey D. Balaban , Mikhaylo Szczupak , Michael E. Hoffer , Robin C. Ashmore , Alexander Kiderman
IPC分类号： A61B3/113 , A61B3/14 , A61B3/11 , A61B3/00 , A61B5/00 , A61B5/12 , A61B3/08 , A61B90/50
摘要： An objective screening platform for mTBI screening includes a vergence testing stimulus generator visible to a subject and configured for presenting visual stimulus to a subject which forms an optical target stimulus for at least one vergence test; at least one data acquisition unit for obtaining objective physiologic responses of the subject unit based upon each of the visual stimulus presented to the subject in each test, wherein the objective physiologic responses for each test include at least one eye position parameter and at least one pupil area parameter; and a controller configured for using at least one eye position parameter and at least one pupil area parameter to screen for the presence of mTBI of the subject.

10. 发明授权

US10314485B2 Portable google based VOG system with comparative left and right eye ocular response analysis with MTBI analysis using percent of saccade function of smooth pursuit test 有权
公开(公告)号：US10314485B2
公开(公告)日：2019-06-11
申请号：US15670553
申请日：2017-08-07
申请人： Neuro Kinetics, Inc.
发明人： Alexander D Kiderman , Ian Shirey , Daniel Sweeney , Yakov Eydelman , John Howison Schroeder
IPC分类号： A61B3/06 , A61B3/14 , A61B3/113 , A61B3/11 , A61B3/00 , A61B3/02
摘要： A head mounted compact goggle based video oculography system comprises: a goggle base surrounding the subject's eyes; an angled hot mirror; at least one digital camera attached to the goggle base along the top side of the goggle base taking images of at least one of the subject's eyes via a hot mirror reflection; an integral display for selectively displaying visual stimulus to the subject through the hot mirror and attached to the goggle base along the rear side of the goggle base; a controller coupled to the display generating each visual stimulus for each neuro-otologic test to be displayed to the subject via the display and coupled to each digital camera and receiving and storing data signals there from, the controller configured to calculate eye related data from the digital camera images during each neuro-otologic test, and configured to display the eye related data to users.

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