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1. 发明专利

JP2007098144A Portable assembly, system, and method for providing functional or therapeutic neuromuscular stimulation 有权
标题翻译：便利的组装，系统和方法提供功能性或治疗性神经元刺激
公开(公告)号：JP2007098144A
公开(公告)日：2007-04-19
申请号：JP2006275853
申请日：2006-10-06
申请人： Ndi Medical Llc , エヌディーアイメディカル, エルエルシー
发明人： THROPE GEOFFREY B , STROTHER ROBERT B , MRVA JOSEPH J
IPC分类号： A61N1/36
摘要： PROBLEM TO BE SOLVED: To provide an improved assembly, system and method for providing neuromuscular stimulation or therapeutic neuromuscular stimulation by prostheses. SOLUTION: The assembly for neuromuscular stimulation is provided with one or more electrodes, a transcutaneous conducting wire, a circuit, and an electrode connection element. The one or more electrodes are made to have a size to be embedded in a nervous tissue region or a muscular tissue being targets and constituted like this. The transcutaneous conducting wire is connected electrically with the electrodes and provided with an exposed area which projects passing through the surface of an external skin. The circuit holds a carrier which is made to have a size to be mounted to the surface of the external skin and and constituted so as to generate a carrier stimulation pulse constituted like this on a substrate. The electrode connection element, which holds the carrier connected electrically to the circuit on the substrate, engages at least a part of the exposed region of the conducting wire so as to connect the electrodes electrically to the circuit and is made to have a size so as to apply a stimulation pulse percutaneously to a tissue region and constituted like this. COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供改进的组装，系统和方法，用于通过假肢提供神经肌肉刺激或治疗性神经肌肉刺激。解决方案：用于神经肌肉刺激的组件设置有一个或多个电极，经皮导电线，电路和电极连接元件。一个或多个电极被制成具有嵌入在神经组织区域中的尺寸或作为靶的肌肉组织，并且如此构成。经皮导线与电极电连接并设置有突出通过外部皮肤表面的暴露区域。电路保持一个载体，该载体被制成具有安装在外表皮表面上的尺寸，并且构成为在基板上产生如此构成的载体刺激脉冲。保持电连接到基板上的电路的载体的电极连接元件接合导线的暴露区域的至少一部分，以将电极电连接到电路，并使其尺寸如将刺激脉冲经皮施加到组织区域并构成。版权所有（C）2007，JPO＆INPIT

2. 发明专利

JP2008100105A Portable assembly, system and method for providing functional or therapeutic neuromuscular stimulation 审中-公开
标题翻译：便携式装置，用于提供功能性或治疗性神经元刺激的系统和方法
公开(公告)号：JP2008100105A
公开(公告)日：2008-05-01
申请号：JP2007335263
申请日：2007-12-26
申请人： Ndi Medical Llc , エヌディーアイメディカル, エルエルシー
发明人： THROPE GEOFFREY B , STROTHER ROBERT B , MRVA JOSEPH J
IPC分类号： A61N1/36
摘要： PROBLEM TO BE SOLVED: To provide an improved assembly, system and method for providing neuromuscular stimulation or therapeutic neuromuscular stimulation by prostheses. SOLUTION: The assembly for neuromuscular stimulation comprises at least one electrode sized and constituted to be embedded in a nervous tissue region or a muscular tissue region set as a target; a percutaneous conductor electrically connected to the electrode and having an exposed area which projects passing through the surface of an external skin; a circuit holding, on a substrate, a carrier sized and constituted to be mounted to the surface of the external skin and constituted to generate stimulation pulse; and an electrode connecting element holding the carrier electrically connected to the circuit, on the substrate, electrically engaging at least a part of the exposed area of the conductor and sized and constituted to apply the stimulation pulse percutaneously to the tissue region. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供改进的组装，系统和方法，用于通过假肢提供神经肌肉刺激或治疗性神经肌肉刺激。解决方案：用于神经肌肉刺激的组件包括至少一个电极，其大小和构造为嵌入在设置为目标的神经组织区域或肌肉组织区域中; 电连接到电极并具有突出通过外部皮肤表面的暴露区域的经皮导体; 在基板上保持尺寸和构造成安装到外部皮肤表面并被构造成产生刺激脉冲的载体的电路; 以及电极连接元件，其保持所述载体电连接到所述电路，在所述基板上，电连接所述导体的暴露区域的至少一部分，并且将其尺寸和构造成经皮刺激所述刺激脉冲至所述组织区域。版权所有（C）2008，JPO＆INPIT

3. 发明专利

JP2007268293A Portable assembly, system and method for providing functional or therapeutic neuromuscular stimulation 有权
标题翻译：便携式装置，用于提供功能性或治疗性神经元刺激的系统和方法
公开(公告)号：JP2007268293A
公开(公告)日：2007-10-18
申请号：JP2007146323
申请日：2007-05-31
申请人： Ndi Medical Llc , エヌディーアイメディカル, エルエルシー
发明人： THROPE GEOFFREY B , STROTHER ROBERT B , MRVA JOSEPH J
IPC分类号： A61N1/32 , A61N1/18
CPC分类号： A61N1/36017 , A61N1/0558 , A61N1/36003 , A61N1/36021 , A61N1/37211
摘要： PROBLEM TO BE SOLVED: To provide improved assembly, system and method for providing functional or therapeutic neuromuscular stimulation by prosthesis. SOLUTION: This neuromuscular stimulation assembly includes: at least one electrode sized and constructed to be embedded in a nerves tissue region or muscles tissue region as a target; a percutaneous conductor electrically coupled to the electrode and projecting through the outer skin surface; a circuit sized to be mounted on the outer skin surface and holding a carrier to generate a carrier stimulus pulse on a substrate; and an electrode connecting element, which is an electrode connecting element holding the carrier electrically coupled to the circuit on the substrate, electrically engages at least a portion of an exposed area of the conductor to electrically couple the electrode to the circuit, and is sized and constructed to percutaneously apply stimulation pulses to the tissue region. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供改进的组装，系统和方法，用于通过假体提供功能性或治疗性神经肌肉刺激。解决方案：该神经肌肉刺激组件包括：至少一个电极，其尺寸和构造被嵌入神经组织区域或肌肉组织区域中作为靶标; 经皮导体，其电耦合到所述电极并突出穿过所述外皮表面; 尺寸设置为安装在外皮表面上并保持载体以在基底上产生载体刺激脉冲的电路; 以及电极连接元件，其是保持所述载体电连接到所述基板上的所述电路的电极连接元件，电接合所述导体的暴露区域的至少一部分以将所述电极电耦合到所述电路，构造成经皮施加刺激脉冲到组织区域。版权所有（C）2008，JPO＆INPIT

4. 发明申请

WO2008085965A3 SYSTEMS AND METHODS INTRA-OPERATIVE STIMULATION 审中-公开
标题翻译：系统和方法手术刺激
公开(公告)号：WO2008085965A3
公开(公告)日：2008-10-23
申请号：PCT/US2008000251
申请日：2008-01-08
申请人： NDI MEDICAL LLC , STROTHER ROBERT B , THROPE GEOFFREY B , MVRA JOSEPH J , GALECKI STEVEN M , PACK DANNY R , THIERFELDER CHRISTOPHER A , COBURN JAMES
发明人： STROTHER ROBERT B , THROPE GEOFFREY B , MVRA JOSEPH J , GALECKI STEVEN M , PACK DANNY R , THIERFELDER CHRISTOPHER A , COBURN JAMES
IPC分类号： A61N1/00
CPC分类号： A61B5/04001 , A61B5/4893 , A61B17/1626 , A61B17/8875 , A61B18/1402 , A61B90/04 , A61B2017/00022 , A61B2017/00154 , A61N1/36014
摘要： Improved assemblies, systems, and methods provide safeguarding against tissue injury during surgical procedures and/or identify nerve damage occurring prior to surgery and/or verify range of motion or attributes of muscle contraction during reconstructive surgery. A stimulation control device may incorporate a range of low and high intensity stimulation to provide a stimulation and evaluation of both nerves and muscles. A stimulation control device is removably coupled to a surgical device or is imbedded within the medical device to provide a stimulation and treatment medical device. A disposable hand held stimulation system includes an operative element extending from the housing, the housing includes an operative element adjustment portion and a visual indication to provide feedback or status to the user.
摘要翻译：改进的组件，系统和方法提供了在手术过程中的组织损伤的保护和/或识别在手术之前发生的神经损伤和/或验证重建手术期间肌肉收缩的运动范围或属性。刺激控制装置可以包括一系列低和高强度刺激，以提供对神经和肌肉的刺激和评估。刺激控制装置可移除地联接到手术装置或嵌入在医疗装置内以提供刺激和治疗医疗装置。一次性手持刺激系统包括从壳体延伸的操作元件，壳体包括操作元件调节部分和用于向使用者提供反馈或状态的视觉指示。

5. 发明专利

AU2020220184A1 WAVEFORM SHAPES FOR TREATING NEUROLOGICAL DISORDERS OPTIMIZED FOR ENERGY EFFICIENCY 未知
公开(公告)号：AU2020220184A1
公开(公告)日：2020-09-10
申请号：AU2020220184
申请日：2020-08-21
申请人： NDI MEDICAL LLC
发明人： GRILL WARREN M , WONGSARNPIGOON AMORN
IPC分类号： A61N1/36
摘要： A stimulation waveform for application to targeted neurological tissue is selected from a set of waveforms consisting essentially of Gaussian curves having varying pulse widths and derived by a prescribed genetic algorithm (GA) coupled to a computational model of extracellular stimulation of a mammalian myelinated axon. The set of stimulus waveforms is optimized for energy efficiency. ') I A i ,on

6. 发明专利

CA2797690C SYSTEMS AND METHODS FOR PERCUTANEOUS ELECTRICAL STIMULATION 未知
公开(公告)号：CA2797690C
公开(公告)日：2020-07-07
申请号：CA2797690
申请日：2011-04-27
申请人： NDI MEDICAL LLC
发明人： RUNDLE KENNETH , GALECKI STEVEN , MARKS MICHAEL , MRVA JOSEPH , SAKAI JONATHAN , STROTHER ROBERT B
IPC分类号： A61N1/36 , A61N1/04
摘要： Systems and methods according to the present invention relate to a substantially extracorporeal pulse generator system for electrical stimulation of one or more target nerve or their branches using one or more preferably percutaneous leads each having one or more electrodes implanted in, on, around, or near the target nerve. Improved systems include a patch assembly configured to be adhesively mounted to a patient's skin and an electrical stimulation assembly configured to be mechanically mounted to the patch assembly. A preferred patch assembly, in addition to provide mechanical mounting of the stimulation assembly, provides a power source for the stimulation assembly, and may further serve as a return electrode. Associated system components and methods of use are also provided.

7. 发明专利

CA137673S COMBINED ELECTRICAL STIMULATOR AND MOUNTING PATCH 未知
公开(公告)号：CA137673S
公开(公告)日：2013-01-04
申请号：CA137673
申请日：2010-10-26
申请人： NDI MEDICAL LLC
摘要： The design is the features of shape, ornamentation, pattern and configuration of the portions of a combined electrical stimulator and mounting patch shown in solid lines in the drawings. The stippled line portions do not form part of the design. The bold wavy lines do not constitute a feature of the design. They are included for illustrative purposes only in order to define the boundary of the design. Drawings of the design are included wherein:Figure 1 is a perspective view of a combined electrical stimulator and mounting patch according to the design;Figure 2 is a front elevation view thereof;Figure 3 is a rear elevation view thereof;Figure 4 is a bottom plan view thereof;Figure 5 is a top plan view thereof;Figure 6 is a right side elevation view thereof; andFigure 7 is a left side elevation view thereof.

8. 发明专利

AU2010281644A1 Systems and methods for maintaining airway patency 未知
公开(公告)号：AU2010281644A1
公开(公告)日：2012-02-23
申请号：AU2010281644
申请日：2010-08-05
申请人： NDI MEDICAL LLC
发明人： BOGGS JOSEPH W , YOO PAUL BYONG SUK
IPC分类号： A61N1/00
摘要： Systems and methods according to the present invention use an electrical pulse generator system, which may be external to or implanted in an animal body, to provide therapeutically effective electrical stimulation to maintain or improve airway patency, such as to treat sleep apnea by the stimulation of target nerve (s) or their branches using one or more leads and one or more electrodes implanted in, on, around, or near the target nerve (s). Examples of a target nerves to be stimulated to maintain or improve upper airway patency, preferably through upper airway muscle reflex activation, are the internal branch of the superior laryngeal nerve (iSLN), the glossopharyngeal nerve, and/or the trigeminal nerve, and/or any of the trunks, branches, or divisions of such nerves.

9. 发明专利

AT520440T 未知
公开(公告)号：AT520440T
公开(公告)日：2011-09-15
申请号：AT05713370
申请日：2005-02-11
申请人： NDI MEDICAL LLC
发明人： THROPE GEOFFREY , STROTHER ROBERT , MRVA JOSEPH
IPC分类号： A61N1/34 , A61N1/18 , A61N1/36
摘要： Neuromuscular stimulation assemblies, systems, and methods make possible the providing of short-term therapy or diagnostic testing by providing electrical connections between muscles or nerves inside the body and stimulus generators or recording instruments mounted on the surface of the skin outside the body. Neuromuscular stimulation assemblies, systems, and methods may include a steerable introducer that defines an interior lumen sized and configured to shield a percutaneous electrode from contact with tissue during advancement to a desired position within tissue.

10. 发明专利

CA2770151A1 SYSTEMS AND METHODS FOR MAINTAINING AIRWAY PATENCY 未知
公开(公告)号：CA2770151A1
公开(公告)日：2011-02-10
申请号：CA2770151
申请日：2010-08-05
申请人： NDI MEDICAL LLC
发明人： BOGGS JOSEPH W , YOO PAUL BYONG SUK
IPC分类号： A61N1/00
摘要： Systems and methods according to the present invention use an electrical pulse generator system, which may be external to or implanted in an animal body, to provide therapeutically effective electrical stimulation to maintain or improve airway patency, such as to treat sleep apnea by the stimulation of target nerve (s) or their branches using one or more leads and one or more electrodes implanted in, on, around, or near the target nerve (s). Examples of a target nerves to be stimulated to maintain or improve upper airway patency, preferably through upper airway muscle reflex activation, are the internal branch of the superior laryngeal nerve (iSLN), the glossopharyngeal nerve, and/or the trigeminal nerve, and/or any of the trunks, branches, or divisions of such nerves.

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