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1. 发明申请

US20220033872A1 DEVICE FOR CAPTURING IN SITU AQUATIC MICROBIOMES 有权
公开(公告)号：US20220033872A1
公开(公告)日：2022-02-03
申请号：US17298428
申请日：2019-11-30
申请人： CIIMAR - CENTRO INTERDISCIPUNAR DE INVESTIGAÇÄO MARINHA E AMBIENTAL , INSTITUTO SUPERIOR DE ENGENHARIA DO PORTO
发明人： Catarina MAGALHÃES , Ana Paula MUCHA , Hugo Manuel DA SILVA RIBEiRO , Maria Fátima CARVALHO , Maria Paola TOMASINO , Marisa ALMEIDA , Sandra RAMOS , Alfredo Manuel DE OLIVEIRA MARTINS , André Miguel PINHEIRO DIAS , Eduardo Alexandre PEREIRA DA SILVA , José Miguel SOARES DE ALMEIDA , Marco MOTA GONÇALVES , Maurício Miguel DE OLIVEIRA GUEDES , Nuno Alexandre NETO DIAS
IPC分类号： C12Q1/24 , G01N1/40 , G01N1/10 , G01N1/14
摘要： The present disclosure relates to a portable device for collecting and/or concentrating in situ plankton microbiome, configured for submersion in water. The device herein disclosed is a compact and low-cost autonomous biosampler, with the ability to yield DNA samples for later genomic analysis.

2. 发明申请

WO2020130862A1 COMPOSIÇÃO FERTILIZANTE LIOFILIZADA COMPREENDENDO QUELATOS DE SIDERÓFOROS DE FERRO, COMPOSIÇÃO LIOFILIZADA COMPREENDENDO SIDERÓFOROS, SEUS PROCESSOS DE OBTENÇÃO E SUAS UTILIZAÇÕES PARA TRATAR PLANTAS 审中-公开
公开(公告)号：WO2020130862A1
公开(公告)日：2020-06-25
申请号：PCT/PT2019/050041
申请日：2019-10-31
申请人： UNIVERSIDADE DO PORTO , INSTITUTO SUPERIOR DE ENGENHARIA DO PORTO , UNIVERSIDAD AUTÓNOMA DE MADRID
发明人： MONTEIRO SOARES, Helena Maria Vieira , HENRIQUES FERREIRA, Carlos Miguel , VALENTE SOARES, Eduardo Jorge , LUCENA MAROTTA, Juan José , LOPÉZ RAYO, Sandra
IPC分类号： C05D9/02 , C05F11/00 , C05G5/10 , C05G5/23 , A01N63/30
摘要： Uma composição fertilizante liofilizada compreendendo quelatos de sideróforos de ferro e um agente estabilizante e a uma composição liofilizada compreendendo sideróforos e um agente estabilizante, em que o agente estabilizante é o amido. A invenção também se refere aos processos de obtenção da composição fertilizante liofilizada e da composição liofilizada compreendendo uma etapa de síntese de pelo menos um composto sideróforo por meio de uma transformação bioquímica executada por pelo menos um microrganismo e à utilização das composições para tratar plantas cultivadas, por exemplo em condições de baixa disponibilidade de ferro, em que as composições possuem a capacidade de corrigir a clorose em plantas, não apresentando riscos ambientais. A composição fertilizante liofilizada e a composição liofilizada possuem uma estabilidade elevada na armazenagem.

3. 发明申请

WO2020110097A1 DEVICE FOR CAPTURING IN SITU AQUATIC MICROBIOMES 审中-公开
公开(公告)号：WO2020110097A1
公开(公告)日：2020-06-04
申请号：PCT/IB2019/060370
申请日：2019-12-02
申请人： CIIMAR - CENTRO INTERDISCIPLINAR DE INVESTIGAÇÃO MARINHA E AMBIENTAL , INSTITUTO SUPERIOR DE ENGENHARIA DO PORTO
发明人： MAGALHÃES, Catarina , DA SILVA RIBEIRO, Hugo Manuel , PINHEIRO DIAS, André Miguel , ALMEIDA, Marisa , TOMASINO, Maria Paola , DE OLIVEIRA GUEDES, Maurício Miguel , RAMOS, Sandra , NETO DIAS, Nuno Alexandre , MUCHA, Ana Paula , CARVALHO, Maria Fátima , DE OLIVEIRA MARTINS, Alfredo Manuel , MOTA GONÇALVES, Marco , PEREIRA DA SILVA, Eduardo Alexandre , SOARES DE ALMEIDA, José Miguel
IPC分类号： C12Q1/24 , G01N1/34
摘要： The present disclosure relates to a portable device for collecting and/or concentrating in situ plankton microbiome, configured for submersion in water. The device herein disclosed is a compact and low-cost autonomous biosampler, with the ability to yield DNA samples for later genomic analysis.

4. 发明申请

WO2015162561A1 COMPOSITION FOR LOCAL AND CONTROLLED RELEASE OF DRUGS AND METHODS THEREOF 审中-公开
标题翻译：用于本地和控制释放药物的组合物及其方法
公开(公告)号：WO2015162561A1
公开(公告)日：2015-10-29
申请号：PCT/IB2015/052916
申请日：2015-04-21
申请人： INEB - INSTITUTO NACIONAL DE ENGENHARIA BIOMÉDICA , UNIVERSIDADE DO PORTO , ISEP - INSTITUTO SUPERIOR DE ENGENHARIA DO PORTO
发明人： MONTEIRO, Fernando Jorge , RIBEIRO E SOUSA MENDES DE FREITAS, Susana Maria , COELHO, Catarina , ALEGRETE DA SILVA, Nuno Paulo
IPC分类号： A61K9/00 , A61L27/12 , A61L27/20 , A61L27/24 , A61K38/14 , A61L27/54 , A61K9/16 , A61K31/43 , A61P19/00 , A61P19/08
CPC分类号： A61K33/42 , A61K9/0019 , A61K9/0024 , A61K9/1611 , A61K9/1658 , A61K9/5036 , A61K9/5052 , A61K9/5089 , A61K31/43 , A61K38/14 , A61K45/06 , A61L27/12 , A61L27/34 , A61L27/54 , A61L2300/236 , A61L2300/406 , A61L2300/602 , C08L89/06
摘要： The present disclosure relates to a composition for treatment and/or prevention of infections, namely bone diseases, in particular osteomyelitis, via a controlled release of antibiotics and subsequently induce regeneration of bone tissue that often undergoes necrosis due to infection. The present disclosure relates in particular to a pharmaceutical composition comprising one or more granules containing calcium phosphate, collagen and one or more polymers of heparin, and an antibiotic in an effective therapeutic amount, wherein the antibiotic is bound to the heparin polymers.
摘要翻译：本公开内容涉及用于治疗和/或预防感染的组合物，即骨疾病，特别是骨髓炎，经由受控释放的抗生素，随后诱导由于感染而经常坏死的骨组织的再生。本公开特别涉及包含一种或多种含有磷酸钙，胶原和一种或多种肝素聚合物的颗粒和有效治疗量的抗生素的药物组合物，其中所述抗生素与肝素聚合物结合。

5. 发明申请

WO2015162559A1 MESH COMPOSITION FOR REPAIRING OR THE REGENERATION OF TISSUES AND METHODS THEREOF 审中-公开
标题翻译：修复组织或组织再生的组合物及其方法
公开(公告)号：WO2015162559A1
公开(公告)日：2015-10-29
申请号：PCT/IB2015/052913
申请日：2015-04-21
申请人： INEB - INSTITUTO NACIONAL DE ENGENHARIA BIOMÉDICA , UNIVERSIDADE DO PORTO , ISEP - INSTITUTO SUPERIOR DE ENGENHARIA DO PORTO
发明人： MONTEIRO, Fernando Jorge , RIBEIRO E SOUSA MENDES DE FREITAS, Susana Maria , LOPES RIBEIRO, Nilza Maria , MORONI, Lorenzo
IPC分类号： A61L27/46 , A61L27/54 , A61L27/56
CPC分类号： A61L27/56 , A61L27/46 , A61L27/54 , A61L2300/214 , A61L2300/252 , A61L2300/258 , A61L2300/414 , A61L2400/12 , A61L2430/02 , A61L2430/06 , A61L2430/12 , A61L2430/34 , C08L89/06
摘要： The present disclosure relates to a matrix or a mesh composition comprising collagen nanofibres and agglomerates of calcium phosphate for the repair and/or regeneration of tissues and in treatment of bone diseases, osteoarthritis or skin diseases. The mesh composition of the invention surprisingly discloses a component combination and structure that renders a more effective mesh composition suitable for mimic a tissue, in particular a bone tissue, and it is also absorbable by the organism after the reconstitution of the tissue, this new mesh composition allows a better and effective tissue regeneration (bone, skin, cartilage).
摘要翻译：本发明涉及包含胶原蛋白纳米纤维和磷酸钙附聚物用于组织修复和/或再生以及治疗骨病，骨关节炎或皮肤疾病的基质或网状组合物。本发明的网状组合物令人惊讶地公开了一种组分组合和结构，其使得更有效的网眼组合物适合于模拟组织，特别是骨组织，并且其在组织重构后也可由生物体吸收，该新网格组合物允许更好和有效的组织再生（骨，皮肤，软骨）。

6. 发明授权

EP3113313B1 METHOD OF CONTROL FOR ELECTRIC POWER MICRONETWORKS AND SYSTEM FOR IMPLEMENTING IT 失效
公开(公告)号：EP3113313B1
公开(公告)日：2018-11-14
申请号：EP15398009.9
申请日：2015-06-30
申请人： Instituto Superior de Engenharia do Porto
发明人： Almeida Do Vale, Zita Maria , Silva Faria, Pedro Nuno , De Oliveira Gomes, Luis Filipe
IPC分类号： H02J3/00 , H02J3/38
CPC分类号： H02J3/38 , H02J2003/007 , Y02A30/62
摘要： The present invention belongs to the field of electrical microgrids optimization and management, which include consuming and generation units, and possibly local generators and equipment suitable for energy storage. The present invention consists therefore on a method for the control of electrical microgrids, which, integrating real data from connected equipment - such as energy generation elements (1) and energy consumption elements (3) - associates that real data with data from simulated elements stored in database (12), aiming at optimizing the microgrid operation, through calculation in computational means (9), scheduling the available resources by actuation means (10). The present invention further comprises, in another innovative facet, the ability of emulating the simulation data results, through means for emulation of load and generation of electrical energy (11). It is also a part of the present invention a system that implements the referred method, in its diverse variants.

7. 发明公开

EP3134071A1 COMPOSITION FOR LOCAL AND CONTROLLED RELEASE OF DRUGS AND METHODS THEREOF 审中-公开
标题翻译：组成为本地和活性物质和药物解放THEREOF
公开(公告)号：EP3134071A1
公开(公告)日：2017-03-01
申请号：EP15723761.1
申请日：2015-04-21
申请人： Ineb-instituto de Engenharia Biomédica , Universidade do Porto , Instituto Superior de Engenharia do Porto
发明人： MONTEIRO, Fernando Jorge , RIBEIRO E SOUSA MENDES DE FREITAS, Susana Maria , COELHO, Catarina , ALEGRETE DA SILVA, Nuno Paulo
IPC分类号： A61K9/00 , A61L27/12 , A61L27/20 , A61L27/24 , A61K38/14 , A61L27/54 , A61K9/16 , A61K31/43 , A61P19/00 , A61P19/08
CPC分类号： A61K33/42 , A61K9/0019 , A61K9/0024 , A61K9/1611 , A61K9/1658 , A61K9/5036 , A61K9/5052 , A61K9/5089 , A61K31/43 , A61K38/14 , A61K45/06 , A61L27/12 , A61L27/34 , A61L27/54 , A61L2300/236 , A61L2300/406 , A61L2300/602 , C08L89/06
摘要： The present disclosure relates to a composition for treatment and/or prevention of infections, namely bone diseases, in particular osteomyelitis, via a controlled release of antibiotics and subsequently induce regeneration of bone tissue that often undergoes necrosis due to infection. The present disclosure relates in particular to a pharmaceutical composition comprising one or more granules containing calcium phosphate, collagen and one or more polymers of heparin, and an antibiotic in an effective therapeutic amount, wherein the antibiotic is bound to the heparin polymers.
摘要翻译：本发明涉及用于治疗和/或预防感染，即骨疾病，特别是骨髓炎的组合物，通过抗生素控释并随后诱导骨组织的再生那样经常下变为坏死因感染。本公开尤其涉及一种包括一个或多个颗粒包含磷酸钙，胶原蛋白和肝素的一种或多种聚合物的药物组合物，并以治疗有效量，worin抗生素结合到肝素聚合物抗生素。

8. 发明公开

EP3708360A1 PRINTED ELECTRODES ON CORK SUBSTRATES AND PROCESS FOR OBTAINING THEM 审中-公开
公开(公告)号：EP3708360A1
公开(公告)日：2020-09-16
申请号：EP19161929.5
申请日：2019-03-11
申请人： Instituto Superior de Engenharia do Porto
发明人： Sales, Maria , Moreira, Ana
IPC分类号： B32B9/02 , G01N27/327 , G01N33/543
摘要： The present invention relates to a cork substrate for printing electrodes, to a cork support comprising electrodes for producing sensing surfaces intended for the electrical transduction of biomolecules, to a biosensor comprising a cork support and to a process for obtaining said substrates, supports and biosensors.
The electrodes are designed on the cork substrates by screen printing techniques. The resulting cork support is suitable for the development of biosensors for any target compound, displaying better electrical features than other supports, while being a low cost and an environmentally friendly approach.
Therefore, the present invention is in the area of devices and materials for analysing biomolecules by the use of electrochemical means.

9. 发明公开

EP3113313A1 METHOD OF CONTROL FOR ELECTRIC POWER MICRONETWORKS AND SYSTEM FOR IMPLEMENTING IT 失效
标题翻译：方法控制其微电网络和系统实现
公开(公告)号：EP3113313A1
公开(公告)日：2017-01-04
申请号：EP15398009.9
申请日：2015-06-30
申请人： Instituto Superior de Engenharia do Porto
发明人： Almeida Do Vale, Zita Maria , Silva Faria, Pedro Nuno , De Oliveira Gomes, Luis Filipe
IPC分类号： H02J3/38
CPC分类号： H02J3/38 , H02J2003/007 , Y02A30/62
摘要： The present invention belongs to the field of electrical microgrids optimization and management, which include consuming and generation units, and possibly local generators and equipment suitable for energy storage.
The present invention consists therefore on a method for the control of electrical microgrids, which, integrating real data from connected equipment - such as energy generation elements (1) and energy consumption elements (3) - associates that real data with data from simulated elements stored in database (12), aiming at optimizing the microgrid operation, through calculation in computational means (9), scheduling the available resources by actuation means (10).
The present invention further comprises, in another innovative facet, the ability of emulating the simulation data results, through means for emulation of load and generation of electrical energy (11).
It is also a part of the present invention a system that implements the referred method, in its diverse variants.
摘要翻译：本发明属于电微电网优化和管理领域，其中包括消费和产生单元，以及可能的本地发电机和设备适合于能量存储。本发明besteht因此，对用于电微网格，其中，从连接的设备INTEGRA廷真实数据的控制的方法 - ：诸如能量产生元件（1）和能量消耗元件（3） - 相关联并存储与来自模拟元件中的数据的真实数据在数据库（12），旨在优化微电网操作，通过在计算装置（9）的计算，通过致动装置（10）调度的可用资源。本发明进一步包括，在另一面的创新，用于将电能（11）的负载和发电的仿真模拟仿真数据的结果，通过装置的能力。因此，本发明的系统那样的一部分实现了由称为在其各种变型的方法。

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