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1. 发明申请

WO2010048177A3 SYSTEMS AND METHODS FOR ANEURYSM TREATMENT AND VESSEL OCCLUSION 审中-公开
标题翻译：用于动脉瘤治疗和血管闭塞的系统和方法
公开(公告)号：WO2010048177A3
公开(公告)日：2010-08-05
申请号：PCT/US2009061319
申请日：2009-10-20
申请人： IMDS INC , DUGGAL NEIL , DE HOOG ROBERT , LEE DONALD , BUTTERS JOSHUA , RAYMOND LOUISE
发明人： DUGGAL NEIL , DE HOOG ROBERT , LEE DONALD , BUTTERS JOSHUA , RAYMOND LOUISE
IPC分类号： A61F2/82 , A61L27/14
CPC分类号： A61F2/06 , A61B17/12022 , A61B17/12118 , A61B17/12136 , A61B17/1214 , A61B17/12168 , A61B17/12177 , A61B17/12186 , A61B17/1219 , A61B2017/00867 , A61B2017/1205 , A61F2/07 , A61F2/856 , A61F2/91 , A61F2002/823 , A61F2002/828
摘要： A system for treating an aneurysm includes an expandable barrier positionable to bridge an aneurysm neck. The barrier may comprise a fiber mesh, balloon or molly anchor member, and may unroll, unfold, or inflate from a compact configuration to an expanded configuration. Expansion of the barrier may be greater radially than axially. A vaso-occlusive member comprising a coil or balloon may be deposited in the aneurysm. Another aneurysm treatment system comprises an outer fenestrated stent and/or an inner fenestrated sleeve, which may be implanted together adjacent an aneurysm neck to regulate blood flow to the aneurysm. The sleeve may move relative to the stent to open or occlude the fenestrations, which may vary in size, shape, and distribution. An intra-luminal vessel occlusion device comprises a stent and a sheath. A drawstring may be actuated to gradually close a sheath orifice to control blood flow through the vessel.
摘要翻译：治疗动脉瘤的系统包括可定位桥接动脉瘤颈的可扩张屏障。屏障可以包括纤维网，球囊或莫利锚固构件，并且可以从紧凑构造展开，展开或膨胀成膨胀构造。屏障的扩张可能比轴向在径向上更大。包含线圈或球囊的血管闭塞构件可以沉积在动脉瘤中。另一种动脉瘤治疗系统包括外部窗孔式支架和/或内部窗孔式套管，其可以邻近动脉瘤颈部一起植入以调节血液流向动脉瘤。套管可以相对于支架移动以打开或闭塞可能在尺寸，形状和分布上不同的开窗。腔内血管阻塞装置包括支架和护套。可以启动束带以逐渐关闭护套孔口以控制通过血管的血液流动。

2. 发明申请

WO2010048189A2 SYSTEMS AND METHODS FOR CEREBROSPINAL FLUID REPAIR 审中-公开
标题翻译：用于脑脊液修复的系统和方法
公开(公告)号：WO2010048189A2
公开(公告)日：2010-04-29
申请号：PCT/US2009/061334
申请日：2009-10-20
申请人： IMDS, INC. , DUGGAL, Neil , RAYMOND, Louise , BUTTERS, Joshua
发明人： DUGGAL, Neil , RAYMOND, Louise , BUTTERS, Joshua
IPC分类号： A61B17/56 , A61L27/14 , A61F2/28
CPC分类号： A61B17/0057 , A61B17/00491 , A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12136 , A61B17/12172 , A61B17/12186 , A61B2017/1205 , A61M29/02
摘要： A system and method for treating a defect. The system may comprise a first expandable barrier insertable into a defect interior space in a compact state and then expanded once positioned inside the defect. The first expandable barrier is expanded to be positioned against the inner surface of the defect. The system may also comprise a second barrier which may be expandable, positioned against the outer surface of the defect. Each of the first and second barriers may expand laterally to a greater extent than axially. The first and second barriers may be in communication through a connection member which couples the two barriers together. The barriers each obliterate the defect and can prevent subsequent CSF or other fluid leaks. Fibrin glue may be introduced into the defect to seal and secure the barriers to the defect. Each barrier may comprise a mesh, a basket, an umbrella or a balloon.
摘要翻译：
一种用于处理缺陷的系统和方法。该系统可以包括第一可膨胀屏障，该第一可膨胀屏障能够以紧凑状态插入缺陷内部空间中，并且随后一旦定位在缺陷内部就膨胀。第一可膨胀屏障扩展到靠着缺陷的内表面定位。该系统还可以包括第二屏障，该第二屏障可以是可膨胀的，抵靠缺陷的外表面定位。第一屏障和第二屏障中的每一个可以比轴向横向地扩展到更大的程度。第一和第二屏障可以通过将两个屏障连接在一起的连接构件连通。每个屏障都会消除缺陷并可以防止后续的CSF或其他流体泄漏。可以将纤维蛋白胶引入缺陷中以密封并固定缺陷的屏障。每个屏障可以包括网格，篮子，伞或气球。

3. 发明申请

WO2010048177A2 SYSTEMS AND METHODS FOR ANEURYSM TREATMENT AND VESSEL OCCLUSION 审中-公开
标题翻译：用于治疗和血管消融的系统和方法
公开(公告)号：WO2010048177A2
公开(公告)日：2010-04-29
申请号：PCT/US2009/061319
申请日：2009-10-20
申请人： IMDS, INC. , DUGGAL, Neil , DE HOOG, Robert , LEE, Donald , BUTTERS, Joshua , RAYMOND, Louise
发明人： DUGGAL, Neil , DE HOOG, Robert , LEE, Donald , BUTTERS, Joshua , RAYMOND, Louise
IPC分类号： A61F2/06 , A61F2/82 , A61L27/14
CPC分类号： A61F2/06 , A61B17/12022 , A61B17/12118 , A61B17/12136 , A61B17/1214 , A61B17/12168 , A61B17/12177 , A61B17/12186 , A61B17/1219 , A61B2017/00867 , A61B2017/1205 , A61F2/07 , A61F2/856 , A61F2/91 , A61F2002/823 , A61F2002/828
摘要： A system for treating an aneurysm includes an expandable barrier positionable to bridge an aneurysm neck. The barrier may comprise a fiber mesh, balloon or molly anchor member, and may unroll, unfold, or inflate from a compact configuration to an expanded configuration. Expansion of the barrier may be greater radially than axially. A vaso-occlusive member comprising a coil or balloon may be deposited in the aneurysm. Another aneurysm treatment system comprises an outer fenestrated stent and/or an inner fenestrated sleeve, which may be implanted together adjacent an aneurysm neck to regulate blood flow to the aneurysm. The sleeve may move relative to the stent to open or occlude the fenestrations, which may vary in size, shape, and distribution. An intra-luminal vessel occlusion device comprises a stent and a sheath. A drawstring may be actuated to gradually close a sheath orifice to control blood flow through the vessel.
摘要翻译：用于治疗动脉瘤的系统包括可扩展的阻挡件，其可定位成桥接动脉瘤颈部。屏障可以包括纤维网，球囊或摩擦锚定构件，并且可以从紧凑构造展开，展开或膨胀到扩展构型。阻挡层的膨胀可以比径向更大。包括线圈或气囊的血管闭塞构件可以沉积在动脉瘤中。另一种动脉瘤治疗系统包括外部开窗支架和/或内部开窗套，其可以邻近动脉瘤颈部植入在一起以调节到动脉瘤的血流。套筒可以相对于支架移动以打开或闭塞开孔，其可以在尺寸，形状和分布上变化。腔内血管闭塞装置包括支架和护套。可以致动束带以逐渐闭合鞘孔以控制通过血管的血流。

4. 发明申请

WO2010080497A3 SYSTEMS AND METHODS FOR DILATION AND DISSECTION OF TISSUES 审中-公开
标题翻译：用于组织的扩张和分离的系统和方法
公开(公告)号：WO2010080497A3
公开(公告)日：2010-09-30
申请号：PCT/US2009068474
申请日：2009-12-17
申请人： IMDS INC , AKYUZ EPHRAIM , GAMBHIR KABIR , STONE CORBETT
发明人： AKYUZ EPHRAIM , GAMBHIR KABIR , STONE CORBETT
IPC分类号： A61B17/34 , A61B17/56 , A61F2/958 , A61M29/02
CPC分类号： A61M25/09 , A61B17/0218 , A61B17/3439 , A61B2017/00261 , A61B2017/320044 , A61M25/10 , A61M29/02
摘要： A minimally invasive dilation device includes a stylus, a plurality of rigid arms radially arrayed about the stylus, and a dilating member positioned between the stylus and the arms. An outer flexible sleeve may be circumferentially secured to the arms, lying within or without the plurality of arms. An inner mesh may surround the stylus and dilating member. The device may be introduced into tissue toward a targeted area, while in a closed configuration. The dilating member may be a balloon, wherein upon inflation of the balloon, the arms are pushed radially outward, expanding the device and dilating the surrounding tissue. A cannula may be inserted inside the plurality of arms to keep the arms in an open configuration, and the stylus, balloon and inner mesh may be withdrawn, providing an open passageway through the device to the targeted area. The device may be used with a neural monitoring system.
摘要翻译：微创扩张装置包括触针，围绕触针径向排列的多个刚性臂以及定位在触针与臂之间的扩张构件。外部柔性套筒可以周向地固定到臂上，位于或不在多个臂内。内网可以围绕触针和扩张构件。该装置可以在闭合构型中被引入组织朝向目标区域。扩张构件可以是气囊，其中在气囊膨胀时，臂被径向向外推动，扩张装置并扩张周围组织。套管可以插入多个臂内以保持臂处于打开构型，并且触针，气囊和内网可以被撤回，从而提供穿过该装置到目标区域的开放通道。该设备可以与神经监测系统一起使用。

5. 发明申请

WO2010048189A3 SYSTEMS AND METHODS FOR CEREBROSPINAL FLUID REPAIR 审中-公开
标题翻译：脑脊髓液修复系统与方法
公开(公告)号：WO2010048189A3
公开(公告)日：2010-08-12
申请号：PCT/US2009061334
申请日：2009-10-20
申请人： IMDS INC , DUGGAL NEIL , RAYMOND LOUISE , BUTTERS JOSHUA
发明人： DUGGAL NEIL , RAYMOND LOUISE , BUTTERS JOSHUA
IPC分类号： A61B17/56 , A61F2/28 , A61L27/14
CPC分类号： A61B17/0057 , A61B17/00491 , A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12136 , A61B17/12172 , A61B17/12186 , A61B2017/1205 , A61M29/02
摘要： A system and method for treating a defect. The system may comprise a first expandable barrier insertable into a defect interior space in a compact state and then expanded once positioned inside the defect. The first expandable barrier is expanded to be positioned against the inner surface of the defect. The system may also comprise a second barrier which may be expandable, positioned against the outer surface of the defect. Each of the first and second barriers may expand laterally to a greater extent than axially. The first and second barriers may be in communication through a connection member which couples the two barriers together. The barriers each obliterate the defect and can prevent subsequent CSF or other fluid leaks. Fibrin glue may be introduced into the defect to seal and secure the barriers to the defect. Each barrier may comprise a mesh, a basket, an umbrella or a balloon.
摘要翻译：用于治疗缺陷的系统和方法。该系统可以包括可以以紧凑状态插入到缺陷内部空间中的第一可扩张的障碍物，然后一旦定位在缺陷内就扩张。第一可扩张屏障被扩张以抵靠缺陷的内表面定位。该系统还可以包括第二阻挡件，其可以是可扩张的，抵靠着缺陷的外表面定位。第一和第二屏障中的每一个可以横向膨胀到比轴向更大的程度。第一和第二屏障可以通过将两个障碍物耦合在一起的连接构件进行通信。障碍每个都消除缺陷，并可以防止后续的CSF或其他液体泄漏。纤维蛋白胶可以引入缺陷中以密封并固定缺陷的障碍物。每个屏障可以包括网，篮，伞或气球。

6. 发明申请

WO2010080497A2 SYSTEMS AND METHODS FOR DILATION AND DISSECTION OF TISSUES 审中-公开
标题翻译：系统和方法用于组织和分离组织
公开(公告)号：WO2010080497A2
公开(公告)日：2010-07-15
申请号：PCT/US2009/068474
申请日：2009-12-17
申请人： IMDS, INC. , AKYUZ, Ephraim , GAMBHIR, Kabir , STONE, Corbett
发明人： AKYUZ, Ephraim , GAMBHIR, Kabir , STONE, Corbett
IPC分类号： A61B17/34 , A61M25/10 , A61M29/02 , A61B17/56
CPC分类号： A61M25/09 , A61B17/0218 , A61B17/3439 , A61B2017/00261 , A61B2017/320044 , A61M25/10 , A61M29/02
摘要： A minimally invasive dilation device includes a stylus, a plurality of rigid arms radially arrayed about the stylus, and a dilating member positioned between the stylus and the arms. An outer flexible sleeve may be circumferentially secured to the arms, lying within or without the plurality of arms. An inner mesh may surround the stylus and dilating member. The device may be introduced into tissue toward a targeted area, while in a closed configuration. The dilating member may be a balloon, wherein upon inflation of the balloon, the arms are pushed radially outward, expanding the device and dilating the surrounding tissue. A cannula may be inserted inside the plurality of arms to keep the arms in an open configuration, and the stylus, balloon and inner mesh may be withdrawn, providing an open passageway through the device to the targeted area. The device may be used with a neural monitoring system.
摘要翻译：微创扩张装置包括触针，围绕触针辐射排列的多个刚性臂以及定位在触笔和手臂之间的扩张构件。外部柔性套筒可周向地固定到臂上，位于或不具有多个臂。内网可围绕触针和扩张构件。当处于关闭状态时，该装置可以朝着目标区域被引入组织。膨胀构件可以是气球，其中当气囊膨胀时，臂被径向向外推动，使装置膨胀并且使周围组织膨胀。套管可以插入多个臂内部以保持臂处于打开构型，并且可以撤回触针，球囊和内网，从而提供通过该装置的目标区域的开放通道。该装置可以与神经监测系统一起使用。

7. 发明公开

EP2376004A2 SYSTEMS AND METHODS FOR DILATION AND DISSECTION OF TISSUES 审中-公开
标题翻译：系统和方法扩张和组织解剖
公开(公告)号：EP2376004A2
公开(公告)日：2011-10-19
申请号：EP09837915.9
申请日：2009-12-17
申请人： IMDS, Inc.
发明人： AKYUZ, Ephraim , GAMBHIR, Kabir , STONE, Corbett
IPC分类号： A61B17/34 , A61M25/10 , A61M29/02 , A61B17/56
CPC分类号： A61M25/09 , A61B17/0218 , A61B17/3439 , A61B2017/00261 , A61B2017/320044 , A61M25/10 , A61M29/02
摘要： A minimally invasive dilation device includes a stylus, a plurality of rigid arms radially arrayed about the stylus, and a dilating member positioned between the stylus and the arms. An outer flexible sleeve may be circumferentially secured to the arms, lying within or without the plurality of arms. An inner mesh may surround the stylus and dilating member. The device may be introduced into tissue toward a targeted area, while in a closed configuration. The dilating member may be a balloon or a cannula. During dilation, the arms are pushed radially outward, expanding the device and dilating the surrounding tissue. A cannula may be inserted inside the plurality of arms to keep the arms in an open configuration, and the stylus and inner mesh may be withdrawn, providing an open passageway through the device to the targeted area. The device may be used with a neural monitoring system.

8. 发明申请

US20100106240A1 Systems and Methods for Aneurysm Treatment and Vessel Occlusion 有权
标题翻译：动脉瘤治疗和血管闭塞的系统和方法
公开(公告)号：US20100106240A1
公开(公告)日：2010-04-29
申请号：US12582052
申请日：2009-10-20
申请人： Neil Duggal , Robert John De Hoog , Donald H. Lee , Louise C. Raymond , Joshua A. Butters
发明人： Neil Duggal , Robert John De Hoog , Donald H. Lee , Louise C. Raymond , Joshua A. Butters
IPC分类号： A61F2/82 , A61M29/00
CPC分类号： A61F2/06 , A61B17/12022 , A61B17/12118 , A61B17/12136 , A61B17/1214 , A61B17/12168 , A61B17/12177 , A61B17/12186 , A61B17/1219 , A61B2017/00867 , A61B2017/1205 , A61F2/07 , A61F2/856 , A61F2/91 , A61F2002/823 , A61F2002/828
摘要： A system for treating an aneurysm includes an expandable barrier positionable to bridge an aneurysm neck. The barrier may comprise a fiber mesh, a balloon or a molly anchor member, and may unroll, unfold, or inflate from a compact configuration to an expanded configuration. Expansion of the barrier may be greater radially than axially. A vaso-occlusive member comprising a coil or balloon may be deposited in the aneurysm. Another aneurysm treatment system comprises an outer fenestrated stent and/or an inner fenestrated sleeve, which may be implanted together adjacent an aneurysm neck to regulate blood flow to the aneurysm. The sleeve may be movable relative to the stent to open or occlude the fenestrations, which may vary in size, shape, and distribution. An intra-luminal vessel occlusion device comprises a stent and a sheath. A drawstring may be actuated to gradually close a sheath orifice to control blood flow through the vessel.
摘要翻译：用于治疗动脉瘤的系统包括可扩展的阻挡件，其可定位成桥接动脉瘤颈部。阻挡层可以包括纤维网，球囊或摩擦锚定构件，并且可以从紧凑构造展开，展开或膨胀到扩展构型。阻挡层的膨胀可以比径向更大。包括线圈或气囊的血管闭塞构件可以沉积在动脉瘤中。另一种动脉瘤治疗系统包括外部开窗支架和/或内部开窗套，其可以邻近动脉瘤颈部植入在一起以调节到动脉瘤的血流。套筒可以相对于支架移动以打开或闭塞开孔，其可以在尺寸，形状和分布上变化。腔内血管闭塞装置包括支架和护套。可以致动束带以逐渐闭合鞘孔以控制通过血管的血流。

9. 发明申请

US20100204737A1 INTERVERTEBRAL IMPLANT WITH INTEGRATED FIXATION 有权
标题翻译：具有整体固定的椎间植入物
公开(公告)号：US20100204737A1
公开(公告)日：2010-08-12
申请号：US12640860
申请日：2009-12-17
申请人： Hyun W. Bae , Dylan M. Hushka , Joshua A. Butters , Nicholas Slater , Daniel F. Justin , Rick Delamarter
发明人： Hyun W. Bae , Dylan M. Hushka , Joshua A. Butters , Nicholas Slater , Daniel F. Justin , Rick Delamarter
IPC分类号： A61B17/88
CPC分类号： A61F2/4455 , A61B17/846 , A61B17/86 , A61F2/442 , A61F2/447 , A61F2002/3007 , A61F2002/3008 , A61F2002/30115 , A61F2002/30126 , A61F2002/30138 , A61F2002/30153 , A61F2002/30166 , A61F2002/30168 , A61F2002/30172 , A61F2002/30176 , A61F2002/30181 , A61F2002/30316 , A61F2002/30352 , A61F2002/30377 , A61F2002/30387 , A61F2002/30401 , A61F2002/30504 , A61F2002/30522 , A61F2002/30598 , A61F2002/30604 , A61F2002/30649 , A61F2002/30736 , A61F2002/30738 , A61F2002/30841 , A61F2002/30845 , A61F2002/30848 , A61F2002/30879 , A61F2002/30884 , A61F2002/30904 , A61F2002/3098 , A61F2002/30983 , A61F2002/4475 , A61F2220/0025 , A61F2220/0033 , A61F2230/0006 , A61F2230/0008 , A61F2230/0017 , A61F2230/0019 , A61F2230/0028 , A61F2230/0043 , A61F2230/0052 , A61F2230/0054 , A61F2230/006 , A61F2250/0098 , A61F2310/00796
摘要： A system for spinal surgery includes a prosthesis comprising a plurality of bone anchors which engage an intervertebral construct for fusion or motion preservation. The fusion construct comprises a spacer optionally encircled by a jacket. The motion preservation construct may comprise an articulating disc assembly or an elastomeric disc assembly. Any of the constructs may occupy the intervertebral disc space between adjacent vertebrae after removal of an intervertebral disc. The anchors slidingly engage the construct to securely fix the prosthesis to the vertebrae. The anchors and jacket of the fusion construct provide a continuous load path across opposite sides of the prosthesis so as to resist antagonistic motions of the spine.
摘要翻译：用于脊柱手术的系统包括假体，其包括多个骨锚固件，其接合用于融合或运动保持的椎间构造物。融合构件包括任选地由护套包围的间隔物。运动保持构造可以包括铰接盘组件或弹性体盘组件。在去除椎间盘之后，任何构造物可能占据相邻椎骨之间的椎间盘间隙。锚固件滑动地接合构造物以将假体牢固地固定到椎骨。融合构件的锚固件和护套提供穿过假体相对侧的连续负载路径，以抵抗脊柱的对抗运动。

10. 发明申请

US20100160947A1 SYSTEMS AND METHODS FOR DILATION AND DISSECTION OF TISSUES 审中-公开
标题翻译：系统和方法用于组织和分离组织
公开(公告)号：US20100160947A1
公开(公告)日：2010-06-24
申请号：US12640413
申请日：2009-12-17
申请人： Ephraim Akyuz , Kabir Gambhir , Corbet W. Stone
发明人： Ephraim Akyuz , Kabir Gambhir , Corbet W. Stone
IPC分类号： A61M29/02 , A61M29/00 , A61B5/00
CPC分类号： A61M25/09 , A61B17/0218 , A61B17/3439 , A61B2017/00261 , A61B2017/320044 , A61M25/10 , A61M29/02
摘要： A minimally invasive dilation device includes a stylus, a plurality of rigid arms radially arrayed about the stylus, and a dilating member positioned between the stylus and the arms. An outer flexible sleeve may be circumferentially secured to the arms, lying within or without the plurality of arms. An inner mesh may surround the stylus and dilating member. The device may be introduced into tissue toward a targeted area, while in a closed configuration. The dilating member may be a balloon, wherein upon inflation of the balloon, the arms are pushed radially outward, expanding the device and dilating the surrounding tissue. A cannula may be inserted inside the plurality of arms to keep the arms in an open configuration, and the stylus, balloon and inner mesh may be withdrawn, providing an open passageway through the device to the targeted area. The device may be used with a neural monitoring system.
摘要翻译：微创扩张装置包括触针，围绕触针放射状排列的多个刚性臂以及定位在触控笔和手臂之间的扩张构件。外部柔性套筒可周向地固定到臂上，位于或不具有多个臂。内网可围绕触针和扩张构件。当处于关闭状态时，该装置可以朝向目标区域被引入组织。扩张构件可以是气囊，其中当气囊膨胀时，臂被径向向外推动，使装置膨胀并且使周围组织膨胀。套管可以插入在多个臂内部以保持臂处于打开构型，并且可以撤回触针，球囊和内网，从而提供通过该装置的目标区域的开放通道。该装置可以与神经监测系统一起使用。

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