专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2017048120A1 BONE VOID FILLING COMPOSITE 审中-公开
标题翻译：骨无孔填充复合材料
公开(公告)号：WO2017048120A1
公开(公告)日：2017-03-23
申请号：PCT/NL2016/050633
申请日：2016-09-14
申请人： FUJIFILM MANUFACTURING EUROPE B.V.
发明人： KLUIJTMANS, Sebastianus Gerardus Johannes Maria , VAN DONGEN, Elisabeth Marianna Wilhelmina Maria , PAWELEC, Kendell Marleen , KNYCHALA, Jonathan
IPC分类号： A61L27/22
CPC分类号： A61L27/46 , A61L2430/02 , C08L89/06
摘要： Composites and scaffolds suitable for bone void filling comprising at least a recombinant gelatin and hydroxyapatite in which the recombinant gelatin comprises glutamic and aspartic acid residues that are distributed homogeneously along a gelatin chain, wherein: (i) the recombinant gelatin comprises a total of at least a 8% glutamic and/or aspartic acids amount per 60 amino acids in row with a standard deviation of at most 1.6; (ii) the hydroxyapatite is obtained by precipitation in the presence of the recombinant gelatin.
摘要翻译：适用于骨空隙填充的复合材料和支架包含至少一种重组明胶和羟基磷灰石，其中重组明胶包含沿着明胶链均匀分布的谷氨酸和天冬氨酸残基，其中：（i）重组明胶至少包含每60个氨基酸排列8％谷氨酸和/或天冬氨酸，标准偏差最大为1.6; （ii）羟基磷灰石是通过在重组明胶存在下沉淀获得的。

2. 发明申请

WO2009126031A1 RECOMBINANT PROTEIN ENRICHED IN A HEPARIN BINDING SITE AND/OR A HEPARAN SULFATE BINDING SITE 审中-公开
标题翻译：在HEPARIN结合位点和/或HEPARAN硫酸盐结合位点中培养的重组蛋白
公开(公告)号：WO2009126031A1
公开(公告)日：2009-10-15
申请号：PCT/NL2009/050179
申请日：2009-04-07
申请人： Fujifilm Manufacturing Europe B.V. , De Boer, Arjo Lysander , Bouwstra, Jan Bastiaan
发明人： De Boer, Arjo Lysander , Bouwstra, Jan Bastiaan
IPC分类号： C07K14/435
CPC分类号： C07K14/78 , A61K9/0024 , A61K9/06 , A61K47/42
摘要： The invention relates to a recombinant protein enriched in a heparin binding site and/or a heparan sulfate binding site. Such recombinant protein is used as an in viva controlled release system of a protein of interest.
摘要翻译：本发明涉及富含肝素结合位点和/或硫酸乙酰肝素结合位点的重组蛋白。这种重组蛋白质用作感兴趣的蛋白质的体外控制释放系统。

3. 发明申请

WO2009082209A1 IMPROVEMENT OF THE SECRETION YIELD OF A PROTEIN OF INTEREST BY IN VIVO PROTEOLYTIC PROCESSING OF A MULTIMERIC PRECURSOR 审中-公开
标题翻译：通过多维前体的体细胞加工中的蛋白质分泌的改善
公开(公告)号：WO2009082209A1
公开(公告)日：2009-07-02
申请号：PCT/NL2008/050808
申请日：2008-12-17
申请人： FUJIFILM MANUFACTURING EUROPE B.V. , BOUWSTRA, Jan Bastiaan , VAN ASTEN, Peter Franciscus Theresius Maria , DE BOER, Arjo Lysander , VAN HAUTUM, Anna Cornelia Hendrika
发明人： BOUWSTRA, Jan Bastiaan , VAN ASTEN, Peter Franciscus Theresius Maria , DE BOER, Arjo Lysander , VAN HAUTUM, Anna Cornelia Hendrika
IPC分类号： C12N15/09 , C12N15/81 , C12N15/62 , C07K14/78
CPC分类号： C12P21/00 , C07K14/78 , C07K2319/50 , C12N15/62 , C12N15/625 , C12N15/815 , C12P21/02 , C12P21/06
摘要： The invention relates to a nucleic acid molecule encoding a multimeric precursor which after transcription is specifically cleaved in vivo to form multiple copies of a protein of interest. The invention further relates to a cell comprising this nucleic acid molecule and a method for producing a protein of interest using this cell.
摘要翻译：本发明涉及编码多聚体前体的核酸分子，其在体内特异性切割转录以形成感兴趣的蛋白质的多个拷贝。本发明还涉及包含该核酸分子的细胞和使用该细胞产生感兴趣的蛋白质的方法。

4. 发明申请

WO2009031886A2 METHOD AND APPARATUS FOR ATOMIC LAYER DEPOSITION USING AN ATMOSPHERIC PRESSURE GLOW DISCHARGE PLASMA 审中-公开
标题翻译：使用大气压力放电等离子体进行原子层沉积的方法和装置
公开(公告)号：WO2009031886A2
公开(公告)日：2009-03-12
申请号：PCT/NL2008/050557
申请日：2008-08-20
申请人： FUJIFILM MANUFACTURING EUROPE B.V. , DE VRIES, Hindrik Willem
发明人： DE VRIES, Hindrik Willem
IPC分类号： C23C16/02 , C23C16/455
CPC分类号： C23C16/452 , C23C16/0245 , C23C16/4554
摘要： Apparatus and method for atomic layer deposition on a surface of a substrate (6) in a treatment space. A gas supply device (15, 16) is present for providing various gas mixtures to the treatment space (1, 2). The gas supply device (15, 16) is arranged to provide a gas mixture with a precursor material to the treatment space for allowing reactive surface sites to react with precursor material molecules to give a surface covered by a monolayer of precursor molecules attached via the reactive sites to the surface of the substrate. Subsequently, a gas mixture comprising a reactive agent capable to convert the attached precursor m molecules to active precursor sites is provided. A plasma generator (10) is present for generating an atmospheric pressure plasma in the gas mixture comprising the reactive agent, the plasma generator being arranged remote from the treatment space (1, 2).
摘要翻译：用于在处理空间中的基板（6）的表面上的原子层沉积的装置和方法。存在用于向处理空间（1,2）提供各种气体混合物的气体供应装置（15,16）。气体供应装置（15,16）被布置成向处理空间提供具有前体材料的气体混合物，以允许反应性表面位点与前体材料分子反应，以产生由单层前体分子覆盖的表面，所述前体分子通过反应性位置到基底的表面。随后，提供包含能够将附着的前体m分子转化成活性前体部位的反应剂的气体混合物。存在等离子体发生器（10），用于在包括反应剂的气体混合物中产生大气压等离子体，等离子体发生器远离处理空间（1,2）布置。

5. 发明申请

WO2008147184A2 ATMOSPHERIC PRESSURE GLOW DISCHARGE PLASMA METHOD AND SYSTEM USING HEATED SUBSTRATE 审中-公开
标题翻译：大气压力放电等离子体方法和使用加热基板的系统
公开(公告)号：WO2008147184A2
公开(公告)日：2008-12-04
申请号：PCT/NL2008/050303
申请日：2008-05-22
申请人： FUJIFILM MANUFACTURING EUROPE B.V. , DE VRIES, Hindrik Willem
发明人： DE VRIES, Hindrik Willem
IPC分类号： H01J37/32
CPC分类号： H01J37/32825 , H01J37/32018 , H01J37/32724
摘要： Method and plasma treatment apparatus for treatment of a substrate, using a pulsed atmospheric pressure glow discharge plasma in a treatment space (5) filled with a gas composition. At least two electrodes (2, 3) are connected to a power supply (4) for providing electrical power to the at least two electrodes (2, 3), a gas supply device (8) for providing a gas composition to the treatment space (5), and a temperature control unit (16) for controlling the temperature of the substrate within a range from above 70 up to 130°C.
摘要翻译：在填充有气体组合物的处理空间（5）中使用脉冲大气压辉光放电等离子体处理衬底的方法和等离子体处理装置。至少两个电极（2,3）连接到用于向至少两个电极（2,3）提供电力的电源（4），用于向处理空间提供气体组成的气体供应装置（8）（5），以及用于在高于70℃至130℃的范围内控制所述基板的温度的温度控制单元（16）。

6. 发明申请

WO2008143516A1 MEMBRANES AND PROCESSES FOR THEIR MANUFACTURE AND USE 审中-公开
标题翻译：其制造和使用的膜和工艺
公开(公告)号：WO2008143516A1
公开(公告)日：2008-11-27
申请号：PCT/NL2008/050312
申请日：2008-05-26
申请人： FUJIFILM MANUFACTURING EUROPE B.V. , ITAMI, Yujiro , KASE, Akira
发明人： ITAMI, Yujiro , KASE, Akira
IPC分类号： B01D53/22 , B01D69/10 , B01D71/52 , B01D67/00
CPC分类号： B01D53/228 , B01D67/0006 , B01D69/02 , B01D69/10 , B01D69/125 , B01D71/52 , B01D2256/10 , B01D2257/504 , B01D2323/30 , B01D2323/34 , B01D2323/345 , B01D2325/027 , B01D2325/20 , Y02C10/10
摘要： A process for preparing a membrane comprising the steps of: (i) Providing a composition comprising a polymerizable compound having at least 25 oxyethylene groups and at least two non-substituted vinyl groups; (ii) Applying said composition to a support thereby forming a continuous layer on the support; (iii) Polymerizing said composition thereby forming a non-porous polymer film. Also claimed are the resultant membranes and their uses, e.g. for separating polar and non-polar gases.
摘要翻译：一种制备膜的方法，包括以下步骤：（i）提供包含具有至少25个氧乙烯基和至少两个未取代的乙烯基的可聚合化合物的组合物; （ii）将所述组合物施用于载体，从而在载体上形成连续层; （iii）聚合所述组合物，从而形成无孔聚合物膜。还要求保护的是所得膜及其用途，例如。用于分离极性和非极性气体。

7. 发明申请

WO2008103046A1 A CONTROLLED RELEASE COMPOSITION 审中-公开
标题翻译：控制释放组成
公开(公告)号：WO2008103046A1
公开(公告)日：2008-08-28
申请号：PCT/NL2008/050106
申请日：2008-02-21
申请人： FUJIFILM Manufacturing Europe B.V. , KLUIJTMANS, Sebastianus Gerardus Johannes Maria , SUTTER, Marc , JISKOOT, Wim , HENNINK, Wilhelmus Everhardus , BOUWSTRA, Jan Bastiaan
发明人： KLUIJTMANS, Sebastianus Gerardus Johannes Maria , SUTTER, Marc , JISKOOT, Wim , HENNINK, Wilhelmus Everhardus , BOUWSTRA, Jan Bastiaan
IPC分类号： A61K9/00 , A61K9/06 , A61K47/42
CPC分类号： A61K9/06 , A61K9/0024 , A61K47/42
摘要： The invention relates to the field of pharmacology. More specific, the invention relates to a controlled release composition. This invention is related to a controlled release composition comprising a cross-linked gelatin and at least one therapeutic protein wherein the ratio of the average mesh size (ξ) of the gelatin matrix and the average hydrodynamic radius (RH) of the therapeutic protein is smaller than 2, preferably smaller than 1.5.
摘要翻译：本发明涉及药理学领域。更具体地说，本发明涉及控释组合物。本发明涉及包含交联明胶和至少一种治疗性蛋白质的控释组合物，其中明胶基质的平均筛网尺寸（α）与治疗性蛋白质的平均流体动力学半径（RH）的比值较小大于2，优选小于1.5。

8. 发明申请

WO2008103044A8 NON-NATURAL RECOMBINANT GELATINS WITH ENHANCED FUNCTIONALITY 审中-公开
公开(公告)号：WO2008103044A8
公开(公告)日：2008-08-28
申请号：PCT/NL2008/050104
申请日：2008-02-21
申请人： FUJIFILM MANUFACTURING EUROPE B.V. , DE BOER, Arjo, Lysander , VAN URK, Hendrik , VAN ASTEN, Peter, Franciscus, Theresius, Maria , BOUWSTRA, Jan, Bastiaan
发明人： DE BOER, Arjo, Lysander , VAN URK, Hendrik , VAN ASTEN, Peter, Franciscus, Theresius, Maria , BOUWSTRA, Jan, Bastiaan
IPC分类号： C07K14/78 , A61K38/39 , A61K38/48 , A61K47/42
摘要： The invention concerns recombinant gelatin monomers and recombinant gelatins comprising or consisting of multimers of the monomers. The recombinant gelatins can be produced with enhanced stability.

9. 发明申请

WO2008103041A1 RECOMBINANT GELATINS 审中-公开
标题翻译：重组凝胶
公开(公告)号：WO2008103041A1
公开(公告)日：2008-08-28
申请号：PCT/NL2008/050098
申请日：2008-02-21
申请人： FUJIFILM MANUFACTURING EUROPE B.V. , DE BOER, Arjo Lysander , VAN URK, Hendrik , VAN ASTEN, Peter Franciscus Theresius Maria , BOUWSTRA, Jan Bastiaan
发明人： DE BOER, Arjo Lysander , VAN URK, Hendrik , VAN ASTEN, Peter Franciscus Theresius Maria , BOUWSTRA, Jan Bastiaan
IPC分类号： C07K14/78 , A61K38/39
CPC分类号： C07K14/78 , A61K38/00 , C12N2531/00 , C12N2533/50
摘要： The invention concerns a recombinant CBE gelatin and recombinant gelatins having multimers of the CBEmonomersequence that are of particular use in several applications involving cell attachment such as in cell culture work and applications involving cell cultures of anchor dependent cells and also in a variety of medical applications.
摘要翻译：本发明涉及具有CBE单体序列多聚体的重组CBE明胶和重组明胶，其在涉及细胞附着的若干应用中特别有用，例如在细胞培养工作和涉及锚定依赖细胞的细胞培养物的应用以及各种医学应用中。

10. 发明申请

WO2008100139A1 SUBSTRATE PLASMA TREATMENT USING MAGNETIC MASK DEVICE 审中-公开
标题翻译：使用磁力遮蔽装置的基板等离子体处理
公开(公告)号：WO2008100139A1
公开(公告)日：2008-08-21
申请号：PCT/NL2008/050054
申请日：2008-02-01
申请人： FUJIFILM MANUFACTURING EUROPE B.V. , DE VRIES, Hindrik, Willem , KORNGOLD, Bruno, Alexander
发明人： DE VRIES, Hindrik, Willem , KORNGOLD, Bruno, Alexander
IPC分类号： H01J37/32
CPC分类号： H01J37/32559 , H01J37/3266
摘要： Plasma treatment apparatus and method for treatment of a surface of a substrate. A dielectric barrier discharge electrode structure is provided having a treatment space (5) and comprising a first el ectrode (2) and a second electrode (3), and a power supply (11) 5 connected to the first electrode (2) and the second electrode (3) for generating an atmospheric pressure plasma in the treatment space (5). The plasma treatment apparatus further comprises a m agnetic layer (6) provided on a surface of at least the first electrode (2). The first electrode (2) is arranged to receive, in operation, the substrate (1) to be treated and a mask device (7) in contact with the substrate (1), the 10 mask device (7) interact ing with the magnetic layer (6).
摘要翻译：用于处理基材表面的等离子体处理装置和方法。提供具有处理空间（5）并且包括第一电极（2）和第二电极（3）的电介质阻挡放电电极结构，以及连接到第一电极（2）和用于在处理空间（5）中产生大气压等离子体的第二电极（3）。等离子体处理装置还包括设置在至少第一电极（2）的表面上的电极层（6）。第一电极（2）被布置成在操作中接收待处理的基板（1）和与基板（1）接触的掩模装置（7），所述10掩模装置（7）与磁体层（6）。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式