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1. 发明申请

WO2017147362A1 METHODS AND SYSTEMS FOR CONTROLLING OR TUNING THE ELECTRIC FIELD GENERATED IN SKIN OR TISSUE DURING COLD PLASMA SKIN TREATMENTS 审中-公开
标题翻译：用于控制或调节冷等离子体皮肤治疗过程中在皮肤或组织中产生的电场的方法和系统
公开(公告)号：WO2017147362A1
公开(公告)日：2017-08-31
申请号：PCT/US2017/019259
申请日：2017-02-24
申请人： EP TECHNOLOGIES, LLC
发明人： KALGHATGI, Sameer , TSAI, Tsung-Chan , LOUIS, Jeffrey, S. , GRAY, Robert, L.
IPC分类号： A61N1/32 , A61N1/44 , H05H1/24
CPC分类号： A61N1/44 , A61B2018/0047 , A61N1/327 , H05H1/2406 , H05H2001/2412 , H05H2245/122
摘要： Exemplary systems and methods associated with skin treatments using non- thermal plasma to porate skin or tissues using conductive elements to direct an electric field through targeted regions of the skin or tissue. Various configurations of conductive elements and associated circuitry may be used to tune and control the electric field.
摘要翻译：与使用非热等离子体皮肤处理相关联的示例性系统和方法使用导电元件来堆叠皮肤或组织以引导电场穿过皮肤或组织的目标区域。导电元件和相关电路的各种配置可以用于调谐和控制电场。

2. 发明申请

WO2016130750A1 PLASMA VAPOR CHAMBER AND ANTIMICROBIAL APPLICATIONS THEREOF 审中-公开
标题翻译：等离子体蒸气室及其抗微生物应用
公开(公告)号：WO2016130750A1
公开(公告)日：2016-08-18
申请号：PCT/US2016/017460
申请日：2016-02-11
申请人： EP TECHNOLOGIES LLC
发明人： FERRELL, James , BOGOVICH, Erinn, R. , GRAY, Robert, L. , ANTONAKAS, Daphne Pappas , TSAI, Tsung-Chan , KALGHATGI, Sameer
IPC分类号： A61L2/14 , H05H1/24
CPC分类号： A61L2/14 , A61L2202/122 , H05H1/2406 , H05H2001/2412
摘要： Exemplary apparatuses and methods of killing or deactivating bacteria are disclosed herein. An exemplary apparatus for killing or deactivating bacteria includes a plasma vapor chamber. The plasma vapor chamber has a vapor inlet for allowing a vapor into the chamber, a high voltage electrode, one or more grounding electrodes. The one or more grounding electrodes at least partially surrounding the plasma vapor chamber. The plasma vapor chamber includes an outlet for allowing fluid to flow out of the chamber. When the chamber is filled with vapor for a period of time sufficient to saturate the chamber with vapor, the high voltage electrode is energized to generate plasma throughout the chamber.
摘要翻译：本文公开了杀死或灭活细菌的示例性装置和方法。用于杀死或灭活细菌的示例性装置包括等离子体蒸气室。等离子体蒸气室具有用于允许蒸气进入室的蒸气入口，高压电极，一个或多个接地电极。一个或多个接地电极至少部分地围绕等离子体蒸气室。等离子体蒸气室包括用于允许流体流出室的出口。当室内充满蒸气一段足以使蒸发室饱和的时间时，高压电极被通电以在整个室中产生等离子体。

3. 发明申请

WO2016069391A1 MEDICAL DEVICE FOR APPLYING NON-THERMAL PLASMA TO SELECTED TARGETS 审中-公开
标题翻译：用于将非热等离子体应用于选定目标的医疗装置
公开(公告)号：WO2016069391A1
公开(公告)日：2016-05-06
申请号：PCT/US2015/057061
申请日：2015-10-23
申请人： EP TECHNOLOGIES LLC
发明人： KALGHATGI, Sameer , PETRAK, David , TSAI, Tsung-Chan , ANTONAKAS, Daphne Pappas , GRAY, Robert, L.
IPC分类号： A61B18/04
CPC分类号： A61N1/44 , A61B18/042 , A61B18/1492 , A61B2018/1226 , H05H1/2406 , H05H2001/2418
摘要： A medical device for directly applying DBD plasma includes a plasma generation module having an electrode surrounded by a dielectric barrier. In one embodiment, when a high voltage source is applied to the electrode, plasma is produced from ambient gas on an outside surface of the plasma generation module. In another embodiment, an enclosure is deployed around the distal end of the plasma generation module surrounding the electrode. Gas flows past the electrode and into the enclosure. In some embodiments, some or all of the gas is removed or pumped out of the enclosure by suction/vacuum. When a high voltage source is applied to the electrode, plasma is produced using the gas flowing into the enclosure.
摘要翻译：用于直接应用DBD等离子体的医疗装置包括具有由电介质阻挡层包围的电极的等离子体产生模块。在一个实施例中，当将高电压源施加到电极时，等离子体由等离子体产生模块的外表面上的环境气体产生。在另一个实施例中，围绕电极的等离子体生成模块的远端周围展开外壳。气体流过电极并进入外壳。在一些实施例中，通过抽吸/真空将部分或全部气体除去或泵出外壳。当高电压源施加到电极时，使用流入外壳的气体产生等离子体。

4. 发明申请

WO2016011117A1 METHODS AND APPARATUS FOR TREATING CROP PLANTS OR PLANT FOOD PRODUCTS WITH PLASMA-ACTIVATED MEDIA TO REDUCE BACTERIAL VIABILITY 审中-公开
标题翻译：用等离子体激活介质处理作物植物或植物食品的方法和装置，以减少细菌毒性
公开(公告)号：WO2016011117A1
公开(公告)日：2016-01-21
申请号：PCT/US2015/040509
申请日：2015-07-15
申请人： EP TECHNOLOGIES, LLC
发明人： FERRELL, James , LEE, Nicholas, R. , ANTONAKAS, Daphne, Pappas , KALGHATGI, Sameer , TSAI, Tsung-Chan , GRAY, Robert, L. , BOGOVICH, Erinn, R.
IPC分类号： A01N3/00 , A01N25/00 , A01N59/00 , A23B7/015 , A23B9/06 , A61L2/14 , A61L2/18
CPC分类号： A23B7/015 , A01N3/00 , A23B7/154 , A23B9/06 , A23L3/3481 , A23L3/3508
摘要： A treated crop plant or plant food product with decreased bacterial viability relative to an untreated crop plant or plant food product. The treated crop plant or plant food product has at least a 1-log reduction in bacterial viability relative to the untreated crop plant or plant food product. Methods and apparatuses of producing the treated crop plant or plant food product are also provided.
摘要翻译：相对于未经处理的作物植物或植物食品，经处理的作物植物或植物食品具有降低的细菌活力。经处理的作物植物或植物食品相对于未经处理的作物植物或植物食品具有至少1-log的细菌活力降低。还提供了生产经处理的作物植物或植物食品的方法和装置。

5. 发明申请

WO2015088948A8 SHAPE CONFORMING FLEXIBLE DIELECTRIC BARRIER DISCHARGE PLASMA GENERATORS 审中-公开
标题翻译：形状柔性柔性介质阻挡放电等离子体发生器
公开(公告)号：WO2015088948A8
公开(公告)日：2015-06-18
申请号：PCT/US2014/069013
申请日：2014-12-08
申请人： EP TECHNOLOGIES LLC
发明人： KALGHATGI, Sameer , TSAI, Tsung-Chan , ANTONAKAS, Daphne, Pappas , GRAY, Robert, L.
IPC分类号： H01J37/32 , H05H1/24 , A61N1/04 , A61L2/14
摘要： Exemplary embodiments of shape conforming dielectric barrier discharge (DBD) plasma generators are disclosed herein. One exemplary embodiment includes a flexible pad and a plurality of electrodes located in the pad within close proximity of each other, and a flexible dielectric barrier surrounding the plurality of electrodes and separating the plurality of electrodes from each other. Wherein when a high voltage pulse is applied to one or more of the plurality of electrodes, plasma is produced between a surface of the flexible pad and a portion of the body in close proximity to the flexible pad.
摘要翻译：这里公开了符合形状的介质阻挡放电（DBD）等离子体发生器的示例性实施例。一个示例性实施例包括柔性衬垫和位于彼此紧密接近的衬垫中的多个电极，以及围绕多个电极并将多个电极彼此分开的柔性电介质阻挡层。其中，当高电压脉冲施加到多个电极中的一个或多个时，在柔性垫的表面和靠近柔性垫的身体部分之间产生等离子体。

6. 发明申请

WO2014152256A1 METHODS AND SOLUTIONS FOR KILLING OR DEACTIVATING BACTERIA 审中-公开
标题翻译：杀死或消灭细菌的方法和解决方案
公开(公告)号：WO2014152256A1
公开(公告)日：2014-09-25
申请号：PCT/US2014/027129
申请日：2014-03-14
申请人： EP TECHNOLOGIES, LLC
发明人： TSAI, Tsung-chan , KALGHATGI, Sameer , ANTONAKAS, Daphne, Pappas , GRAY, Robert, L.
IPC分类号： C02F1/46 , A01N61/00 , A61L2/14 , A61L2/18
CPC分类号： A61L2/18 , A01N59/00 , A01N61/00 , C02F1/4608 , C02F2303/04 , C02F2305/02
摘要： Exemplary methods for killing or deactivating bacteria are provided herein. One exemplary method includes providing a plasma system and a filter below the plasma system. Energizing the plasma generator to create indirect plasma downstream of the filter and activating a fluid with the indirect plasma and applying the activated fluid to bacteria is shown to deactivate and kill bacteria.
摘要翻译：本文提供了杀死或灭活细菌的示例性方法。一种示例性方法包括在等离子体系统下方提供等离子体系统和过滤器。激发等离子体发生器以在过滤器的下游产生间接的血浆，并且用间接血浆激活流体并将活化的流体施用于细菌被显示为使细菌失活和杀死。

7. 发明申请

WO1997045156A2 TISSUE HEATING AND ABLATION SYSTEMS AND METHODS USING POROUS ELECTRODE STRUCTURES 审中-公开
标题翻译：组织加热和吸收系统和使用多孔电极结构的方法
公开(公告)号：WO1997045156A2
公开(公告)日：1997-12-04
申请号：PCT/US1997001177
申请日：1997-01-17
申请人： EP TECHNOLOGIES, INC.
发明人： EP TECHNOLOGIES, INC. , SWANSON, David, K. , PANESCU, Dorin , WHAYNE, James, G. , OWENS, Patrick, M. , FLEISCHMAN, Sidney, D. , THOMPSON, Russell, B. , JACKSON, Jerome
IPC分类号： A61N00/00
CPC分类号： A61B18/1492 , A61B2018/00065 , A61B2018/00083 , A61B2018/00095 , A61B2018/00113 , A61B2018/00148 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00761 , A61B2018/00839 , A61B2018/00886 , A61B2018/1253 , A61B2018/1467 , A61B2018/1472 , A61B2218/002
摘要： Porous electrode assemblies for tissue heating and ablation systems and methods enable ionic transport of electrical energy to occur substantially free of liquid perfusion.
摘要翻译：用于组织加热和消融系统和方法的多孔电极组件使电能的离子转运基本上不含液体灌注。

8. 发明申请

WO1997042996A1 ASSEMBLIES FOR CREATING COMPOUND CURVES IN DISTAL CATHETER REGIONS 审中-公开
标题翻译：用于创建远程导管区域的化合物曲线的组件
公开(公告)号：WO1997042996A1
公开(公告)日：1997-11-20
申请号：PCT/US1997005624
申请日：1997-04-03
申请人： EP TECHNOLOGIES, INC.
发明人： EP TECHNOLOGIES, INC. , THOMPSON, Russell, B. , FLEISCHMAN, Sidney, D. , WHAYNE, James, G. , SWANSON, David, K.
IPC分类号： A61M25/00
CPC分类号： A61M25/0144 , A61B2018/00916 , A61B2018/00952 , A61M25/0105 , A61M25/0136 , A61M25/0147 , A61M25/0152 , A61M2025/0161 , A61M2025/0163
摘要： Compound steering assemblies (28), usable in both diagnostic and therapeutic applications, enable a physician to swiftly and accurately steer the distal section (16) of the catheter (10) in multiple planes or complex curves to position and maintain ablation and/or mapping electrodes (18) in intimate contact with an interior body surface.
摘要翻译：可用于诊断和治疗应用的复合转向组件（28）使得医生能够快速且精确地将多个平面或复合曲线中的导管（10）的远端部分（16）引导以定位和维持消融和/或映射电极（18）与内部主体表面紧密接触。

9. 发明申请

WO1997017904A1 FLEXIBLE TISSUE ABLATION ELEMENTS FOR MAKING LONG LESIONS 审中-公开
标题翻译：柔软的组织吸收元素，用于制作长片
公开(公告)号：WO1997017904A1
公开(公告)日：1997-05-22
申请号：PCT/US1996018101
申请日：1996-11-08
申请人： EP TECHNOLOGIES, INC.
发明人： EP TECHNOLOGIES, INC. , FLEISCHMAN, Sidney, D. , THOMPSON, Russell, B. , PANESCU, Dorin , SWANSON, David, K.
IPC分类号： A61B17/36
CPC分类号： A61B18/1492 , A61B5/0422 , A61B5/6858 , A61B2017/00088 , A61B2017/00092 , A61B2017/0088 , A61B2018/00083 , A61B2018/00107 , A61B2018/00148 , A61B2018/0016 , A61B2018/00791 , A61B2018/1435 , A61N1/056 , A61N1/06 , A61N1/40 , G01K1/026 , G01K3/14
摘要： This invention is devices and methods for ablating body tissue which use wire (44) wound about a support body (12) in adjacent windings to form one or more elongated electrodes. A connection couples the wire to a source of ablation energy for transmission by the elongated electrode to ablate tissue. The adjacent windings are spaced apart to impart enhanced flexibility to the elongated electrode during use.
摘要翻译：本发明是用于消融身体组织的装置和方法，其使用围绕相邻绕组中的支撑体（12）缠绕的线（44）以形成一个或多个细长电极。连接将电线耦合到消融能量源，以通过细长电极传输以消融组织。相邻的绕组间隔开以在使用期间赋予细长电极增强的柔性。

10. 发明申请

WO1996025097A1 SYSTEMS AND METHODS FOR EXAMINING HEART TISSUE 审中-公开
标题翻译：用于检查心脏组织的系统和方法
公开(公告)号：WO1996025097A1
公开(公告)日：1996-08-22
申请号：PCT/US1996002190
申请日：1996-02-16
申请人： EP TECHNOLOGIES, INC.
发明人： EP TECHNOLOGIES, INC. , SWANSON, David, K. , PANESCU, Dorin , WHAYNE, James, G.
IPC分类号： A61B05/0402
CPC分类号： A61B5/6855 , A61B5/0422 , A61B5/6858 , A61B18/1492 , A61B2090/065 , A61B2562/0209 , A61B2562/043 , A61N1/056
摘要： Systems and methods use an array (20) of multiple electrodes (24) supported for operative association with a region of heart tissue, in tandem with a roving second electrode (36) supported for movement relative to the multiple electrodes for operative association with selected different regions of endocardial tissue within the heart. An analog or digital processing element (32) conditions one of the multiple electrodes and the roving electrode to emit a pacing signal while the other one of the multiple electrodes and the roving electrode records paced electro-grams occurring as a result of the pacing signal. A template of cardiac event of known diagnosis sensed using the array of multiple electrodes is input. A sample of a cardiac event acquired by pacing from at least one roving electrode and sensed with the array of multiple electrodes is input. The processing element and method electronically compare the sample to a template and generate an output.
摘要翻译：系统和方法使用多个电极（24）的阵列（20），其被支撑用于与心脏组织的区域有效地相关联，与被支撑用于相对于多个电极移动的粗纱第二电极（36）串联，以与所选择的不同的心脏内心脏组织的区域。模拟或数字处理元件（32）调节多个电极和粗纱电极之一以发出起搏信号，而多个电极和粗纱电极中的另一个记录起搏电针作为起搏信号的结果。输入使用多个电极阵列感测的已知诊断的心脏事件的模板。输入通过起搏从至少一个粗纱电极获取的心脏事件的样本，并用多个电极的阵列感测。处理元件和方法将样本与模板进行电子比较并生成输出。

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