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1. 发明专利

ES2731331T3 Sistema y método para procesar señales de catéteres intracardiacos 未知
公开(公告)号：ES2731331T3
公开(公告)日：2019-11-15
申请号：ES16717116
申请日：2016-04-08
申请人： CATHVISION APS
发明人： MATTHIESEN MADS EMIL , LARSEN SIGGE NEJST
IPC分类号： A61B5/00 , A61B5/308
摘要： Sistema para registrar señales intracardiacas y para proporcionar impulsos de estimulación y/o energía de ablación en ubicaciones intracardiacas, comprendiendo el sistema: - una pluralidad de terminales intracardiacos (10a-d) adaptados para recoger potenciales electrofisiológicos intracardiacos de una pluralidad de electrodos intracardiacos pasivos (1a-d) en ubicaciones intracardiacas respectivas en un individuo (99); - un terminal indiferente (20) adaptado para recoger potenciales electrofisiológicos indiferentes de uno o más electrodos indiferentes (2) en o sobre el individuo (99); - una etapa de amplificador diferencial (30) adaptada para recibir y amplificar los potenciales electrofisiológicos recolectados de los terminales intracardiacos e indiferentes (10a-d, 20) con respecto a una referencia de señal para obtener las señales respectivas intracardiacas e indiferentes (201a-d, 202); y - un dispositivo procesador 40 adaptado para determinar una señal de modo común (900) como promedio de las señales intracardiacas e indiferentes (201a-d, 202) y adaptado para proporcionar una salida de datos intracardiacos basados al menos en las señales intracardiacas (201a-d), en donde las señales intracardiacas (201a-d) están referenciadas con respecto a la señal de modo común (900).

2. 发明专利

DK3280316T3 SYSTEM OG FREMGANGSMÅDE TIL PROCESSERING AF SIGNALER FRA INTRAKARDIALE KATETRE 未知
公开(公告)号：DK3280316T3
公开(公告)日：2019-06-24
申请号：DK16717116
申请日：2016-04-08
申请人： CATHVISION APS
发明人： MATTHIESEN MADS EMIL , LARSEN SIGGE NEJST
IPC分类号： A61B5/00 , A61B5/308

3. 发明申请

WO2018069509A1 SYSTEM FOR ADAPTIVE FILTERING OF CARDIAC SIGNALS 审中-公开
标题翻译：自适应滤波心脏信号的系统
公开(公告)号：WO2018069509A1
公开(公告)日：2018-04-19
申请号：PCT/EP2017/076208
申请日：2017-10-13
申请人： CATHVISION APS
发明人： MATTHIESEN, Mads Emil , LARSEN, Sigge Nejst
IPC分类号： A61B5/04 , A61B5/0452 , A61B5/00 , A61B5/0408 , A61B5/042
摘要： System for filtering cardiac signals, the system comprising: a plurality of cardiac terminals (10a-d) adapted to collect cardiac electrophysiological potentials from a plurality of cardiac electrodes (1a-d) placed at respective cardiac locations in or on an individual (99) and a processor device (40) adapted to process one or more input signals which are based on the collected electrophysiological potential(s). The processing comprises running an adaptive filter algorithm on one or more signals based on the input signals, said adaptive filter algorithm being arranged to calculate one or more estimated noise component(s) of said one or more signals and being arranged to subtract said one or more estimated noise component(s) respectively from said one or more signals. In this way a cardiac signal is derived where the noise has been significantly reduced.
摘要翻译：用于过滤心脏信号的系统，所述系统包括：多个心脏终端（10a-d），其适于从放置在各个心脏位置处的多个心脏电极（1a-d）收集心脏电生理学电位在个人（99）和处理器设备（40）中或其上，处理器设备（40）适于处理基于所收集的一个或多个电生理学潜能的一个或多个输入信号。该处理包括基于输入信号对一个或多个信号运行自适应滤波器算法，所述自适应滤波器算法被配置为计算所述一个或多个信号中的一个或多个估计噪声分量并且被设置为从所述一个或多个信号中减去所述一个或多个信号从所述一个或多个信号分别估计更多的噪声分量。通过这种方式，可以在噪音显着降低的情况下获得心脏信号。

4. 发明申请

WO2016162497A1 SYSTEM AND METHOD FOR PROCESSING SIGNALS FROM INTRACARDIAC CATHETERS 审中-公开
标题翻译：用于处理来自肠杆菌吸虫的信号的系统和方法
公开(公告)号：WO2016162497A1
公开(公告)日：2016-10-13
申请号：PCT/EP2016/057783
申请日：2016-04-08
申请人： CATHVISION APS
发明人： MATTHIESEN, Mads Emil , LARSEN, Sigge, Nejst
IPC分类号： A61B5/00 , A61B5/0428
CPC分类号： A61B5/0428 , A61B5/0476 , A61B5/6852 , A61B5/7203 , A61N1/368
摘要： The present invention relates in one aspect to a system for recording intracardiac signals and for providing stimulation pulses and /or ablation energy at intracardiac locations. The system comprises a plurality of intracardiac terminals adapted to collecting intracardiac electrophysiological potentials from respective intracardiac locations in an individual; an indifferent terminal adapted to collecting indifferent electrophysiological potentials from the individual; a differential amplifier stage adapted to receiving and amplifying the electrophysiological potentials collected from the intracardiac and indifferent terminals with respect to a signal reference to obtain respective intracardiac and indifferent signals; a processor device adapted to determining a common mode signal as an average of the intracardiac and indifferent signals and adapted to providing an output of intracardiac data based at least on the intracardiac signals, wherein the intracardiac signals are referenced with respect to the common mode signal. The invention relates further to a method of processing intracardiac electrophysiological signals.
摘要翻译：本发明在一个方面涉及用于记录心内信号并用于在心脏内位置处提供刺激脉冲和/或消融能量的系统。该系统包括多个心内终端，其适于从各个心脏位置收集心内电生理电位; 一个无关紧要的终端，适合于从个人收集无关的电生理潜能; 差分放大器级，用于接收和放大从心尖和无关终端收集的关于信号参考的电生理学电位，以获得相应的心内和无关信号; 处理器装置，其适于将共模信号确定为心内和无关信号的平均值，并且适于至少基于心内信号提供心内数据的输出，其中相对于共模信号参考心内信号。本发明还涉及一种处理心内电生理信号的方法。

5. 发明申请

WO2019211156A1 ISOLATION AMPLIFICATION CIRCUIT WITH IMPROVED COMMON MODE REJECTION 审中-公开
公开(公告)号：WO2019211156A1
公开(公告)日：2019-11-07
申请号：PCT/EP2019/060584
申请日：2019-04-25
申请人： CATHVISION APS
发明人： WODLINGER, Harold , BIEL, Arkadiusz , XI, Hogyu , FINE, Richard
IPC分类号： H03F3/45 , H03F1/26 , A61B5/0428 , A61B5/00
摘要： The present invention relates to an isolation amplification circuit which comprises an input stage circuitry and a control circuitry stage interconnected through a galvanic isolation barrier. The input stage circuitry comprises a first filter network and a second filter network for supplying first and second output signals in response to the application of first and second electrical input signals. The input stage circuitry comprises a first feedback path configured for applying a first feedback signal to a common node of the first filter network to close a first feedback loop around the first filter network and a second feedback path configured for applying a second feedback signal to a common node of the second filter network to close a second feedback loop around the second filter network.

6. 发明申请

WO2019175156A1 SYSTEM AND METHOD FOR PROCESSING ELECTROPHYSIOLOGICAL SIGNALS 审中-公开
公开(公告)号：WO2019175156A1
公开(公告)日：2019-09-19
申请号：PCT/EP2019/056136
申请日：2019-03-12
申请人： CATHVISION APS
发明人： LARSEN, Sigge Nejst , SHADBOLT, Victor , MACADAM, David P. , WODLINGER, Harold
IPC分类号： A61B5/0428 , A61B5/00 , A61N1/365 , A61B5/042 , A61B18/00
摘要： The present invention relates to an electrophysiology system comprising one or more signal channels, wherein each signal channel is adapted for processing an electrophysiological signal along a signal path. The signal path extends from an input port configured for receiving the electrophysiological signal as an analog signal, via at least one adjustable gain element adapted for amplifying the electrophysiological signal with a gain according to a gain setting, and via an ADC element adapted for converting the analog signal into a digital signal corresponding to the electrophysiological signal, to an output port arranged for providing the digital signal as an output. The electrophysiology system further comprises a monitoring element configured for generating a monitoring signal representative of a magnitude of a DC component of the electrophysiological signal and a gain control element configured for generating a control signal in response to the monitoring signal. The control signal is adapted to control the gain setting of the adjustable gain element so as to cause a decrease in gain, if an increase in the magnitude of the DC component is determined; and/or an increase in gain, if a decrease in the magnitude of the DC component is determined.

7. 发明申请

WO2023020843A1 METHOD FOR DETECTING A CARDIAC ISOLATION STATUS OF A MEASUREMENT LOCATION IN THE PRESENCE OF FAR FIELD INTERFERENCE 审中-公开
公开(公告)号：WO2023020843A1
公开(公告)日：2023-02-23
申请号：PCT/EP2022/071843
申请日：2022-08-03
申请人： CATHVISION APS
发明人： PAAMAND, Rune , MATTHIESEN, Mads Emil
IPC分类号： A61B5/35 , A61B5/361 , A61B5/00 , G16H50/20
摘要： The invention concerns a method for determining a cardiac isolation status of a measurement location (1) in the presence of far field interference by analysing a multi-channel intracardiac electrogram (2) of the measurement location (1) via a control system (3), wherein in an identification routine (9) the control system (3) applies an activation search algorithm to analysis windows (10) of at least 400 ms in at least two different channels (11) of the intracardiac electrogram (2), wherein the activation search algorithm identifies windows (W) of local activation potentials (12) inside of the analysis windows (10), wherein in a classification routine (15) the control system (3) analyses the local activation potentials (12) to determine the cardiac isolation status of the measurement location (1).

8. 发明申请

WO2022122192A1 METHOD FOR CLASSIFYING ATRIAL FIBRILLATION 审中-公开
公开(公告)号：WO2022122192A1
公开(公告)日：2022-06-16
申请号：PCT/EP2021/073107
申请日：2021-08-20
申请人： CATHVISION APS [DK]/[DK]
发明人： PAAMAND, Rune , MATTHIESEN, Mads Emil
IPC分类号： A61B5/361 , A61B5/00
摘要： The invention relates to a method for classifying atrial fibrillation by analysing ECG data (1) via a control system (2), wherein in a decomposition step the control system (2) decomposes the ECG data (1) by a frequency decomposition thereby generating frequency data (7), in particular a frequency spectrum, comprising a frequency dimension (f) and an amplitude dimension (a). It is proposed that in an analysis step the control system (2) identifies in the frequency data (7) a dominant window (8) having a width (9) in the frequency dimension (f) and meeting an amplitude criterion, that the amplitude criterion is based on a sum of amplitudes inside the dominant window (8), that the control system (2) identifies the dominant window (8) by searching on at least a section, in particular a pre-defined section, of the frequency dimension (f) for a window fulfilling the amplitude criterion and that based on the dominant window (8) the control system (2) determines the classification of atrial fibrillation in the ECG data (1).

9. 发明专利

CA3078755A1 SYSTEM FOR ADAPTIVE FILTERING OF CARDIAC SIGNALS 未知
公开(公告)号：CA3078755A1
公开(公告)日：2018-04-19
申请号：CA3078755
申请日：2017-10-13
申请人： CATHVISION APS
发明人： MATTHIESEN MADS EMIL , LARSEN SIGGE NEJST
IPC分类号： A61B5/308 , A61B5/00 , A61B5/296
摘要： System for filtering cardiac signals, the system comprising: a plurality of cardiac terminals (10a-d) adapted to collect cardiac electrophysiological potentials from a plurality of cardiac electrodes (1a-d) placed at respective cardiac locations in or on an individual (99) and a processor device (40) adapted to process one or more input signals which are based on the collected electrophysiological potential(s). The processing comprises running an adaptive filter algorithm on one or more signals based on the input signals, said adaptive filter algorithm being arranged to calculate one or more estimated noise component(s) of said one or more signals and being arranged to subtract said one or more estimated noise component(s) respectively from said one or more signals. In this way a cardiac signal is derived where the noise has been significantly reduced.

10. 发明专利

CA3078740A1 FILTERING DEVICE FOR RECORDING ELECTROPHYSIOLOGICAL SIGNALS 未知
公开(公告)号：CA3078740A1
公开(公告)日：2018-04-19
申请号：CA3078740
申请日：2017-10-13
申请人： CATHVISION APS
发明人： MATTHIESEN MADS EMIL , LARSEN SIGGE NEJST , SHADBOLT VICTOR , WODLINGER HAROLD
IPC分类号： A61B18/12 , A61B5/296 , A61B5/308 , A61B18/14
摘要： The present invention relates to a switchable filter device for use in a system for recording electro-physiological signals. The filter device comprises a plurality of recording channels, the recording channels comprising an ablation recording channel. Each recording channel has a patient side terminal at a patient interface and a corresponding recording side terminal at a recording device interface. Each recording channel comprises a first signal path with a first frequency dependent transmission characteristic having a first pass band, a second signal path with a second frequency dependent transmission characteristic different from the first frequency dependent transmission characteristic, the second frequency dependent transmission characteristic having a second pass band overlapping the first pass band, and switching devices operable to switch between the first signal path and the second signal path in response to a control signal indicative of a transient interference signal. Preferably, switching from the second signal path to the first signal path is performed with a switching delay after termination of the transient interference signal.

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