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1. 发明申请

WO2015179969A1 JOINT SPECTROSCOPIC AND BIOSENSOR SYSTEM FOR POINT-OF-CARE TESTING 审中-公开
标题翻译：用于点心测试的联合光谱和生物传感器系统
公开(公告)号：WO2015179969A1
公开(公告)日：2015-12-03
申请号：PCT/CA2015/050455
申请日：2015-05-20
申请人： CHROMEDX CORP.
发明人： SAMSOONDAR, James
IPC分类号： G01N33/72 , A61B5/1455 , A61B5/157
CPC分类号： G01N33/49 , A61B5/150022 , A61B5/150343 , A61B5/157 , B01L3/502 , B01L3/561 , B01L2200/10 , B01L2300/04 , B01L2300/0636 , G01N33/4915
摘要： Some embodiments of the invention provide a system for measurement of at least two hemoglobin species in a patient's blood sample by spectroscopy, and measurement of at least pH of the blood sample by biosensor. The system comprises a disposable cartridge adapted for insertion into a slot of an analyzer, and the results are used to monitor the acid-base status of a patient. A method for monitoring the acid-base status of a patient using the system is also provided.
摘要翻译：本发明的一些实施方案提供了一种用于通过光谱法测量患者血液样品中的至少两种血红蛋白物质并通过生物传感器至少测量血液样品的pH的系统。该系统包括适于插入分析器的槽中的一次性盒，并且结果用于监测患者的酸碱状态。还提供了一种用于监测使用该系统的患者的酸碱状态的方法。

2. 发明申请

WO2017165967A1 POINT-OF-CARE TESTING SYSTEM FOR BLOOD GASES AND CO-OXIMETRY 审中-公开
标题翻译： POINT-OF-CARE测试系统用于血气和CO氧化测试
公开(公告)号：WO2017165967A1
公开(公告)日：2017-10-05
申请号：PCT/CA2017/050379
申请日：2017-03-27
申请人： CHROMEDX CORP.
发明人： SAMSOONDAR, James
IPC分类号： G01N21/25 , A61B5/15 , A61B5/153 , A61J1/20
摘要： A cartridge and system involving a joint spectroscopic and biosensor blood analyzer for measurement of at least two hemoglobin species in a patient's blood sample by spectroscopy, and measurement of at least pH of the blood sample by biosensor, for assessing the patient's oxygenation and acid-base status. The cartridge comprises a housing having a first housing member and a second housing member bonded together by a gasket. The housing comprises a cartridge inlet; a blood storage conduit; an optical chamber; a biosensor conduit; a waste receptacle; a vent; an air bladder, an air bladder exit port; and, an optical window and an aligned optical member, the aligned optical member being one of a reflecting member or a second optical window, and being positioned to align with at least a portion of the optical chamber and at least a portion of the optical window.
摘要翻译：包括联合光谱学和生物传感器血液分析仪的盒和系统，用于通过光谱法测量患者血液样品中的至少两种血红蛋白物种，以及通过生物传感器测量血液样品的至少pH，评估患者的氧合和酸碱状态。盒包括壳体，壳体具有通过垫圈结合在一起的第一壳体构件和第二壳体构件。该壳体包括盒入口; 血液贮存导管; 一个光学室; 生物传感器导管; 废物容器; 通风口; 气囊，气囊出口; 以及光学窗口和对准的光学构件，所述对准的光学构件是反射构件或第二光学窗口中的一个，并且定位成与所述光学室的至少一部分对准，并且所述光学窗口的至少一部分

3. 发明公开

EP3436801A1 POINT-OF-CARE TESTING SYSTEM FOR BLOOD GASES AND CO-OXIMETRY 审中-公开
公开(公告)号：EP3436801A1
公开(公告)日：2019-02-06
申请号：EP17772902.7
申请日：2017-03-27
申请人： Chromedx Corp.
发明人： SAMSOONDAR, James
IPC分类号： G01N21/25 , A61B5/15 , A61B5/153 , A61J1/20

4. 发明专利

CA2876602A1 AUTOMATED ULTRA-FILTRATION SYSTEM 未知
公开(公告)号：CA2876602A1
公开(公告)日：2014-06-12
申请号：CA2876602
申请日：2013-12-06
申请人： CHROMEDX CORP
发明人： SAMSOONDAR JAMES
IPC分类号： G01N35/10 , G01N1/34 , G01N35/02

5. 发明授权

US09470673B2 Joint spectroscopic and biosensor system for point-of-care testing 有权
标题翻译：联合光谱和生物传感器系统进行点对点测试
公开(公告)号：US09470673B2
公开(公告)日：2016-10-18
申请号：US15144073
申请日：2016-05-02
申请人： ChroMedX Corp.
发明人： James Samsoondar
IPC分类号： G01N33/49 , B01L3/00
CPC分类号： G01N33/49 , A61B5/150022 , A61B5/150343 , A61B5/157 , B01L3/502 , B01L3/561 , B01L2200/10 , B01L2300/04 , B01L2300/0636 , G01N33/4915
摘要： Some embodiments of the invention provide a system for measurement of at least two hemoglobin species in a patient's blood sample by spectroscopy, and measurement of at least pH of the blood sample by biosensor. The system comprises a disposable cartridge adapted for insertion into a slot of an analyzer, and the results are used to monitor the acid-base status of a patient. A method for monitoring the acid-base status of a patient using the system is also provided.
摘要翻译：本发明的一些实施方案提供了一种用于通过光谱法测量患者血液样品中的至少两种血红蛋白物质并通过生物传感器至少测量血液样品的pH的系统。该系统包括适于插入分析器的槽中的一次性盒，并且结果用于监测患者的酸碱状态。还提供了一种用于监测使用该系统的患者的酸碱状态的方法。

6. 发明申请

US20170205323A1 AUTOMATED ULTRA-FILTRATION WORKSTATION 审中-公开
公开(公告)号：US20170205323A1
公开(公告)日：2017-07-20
申请号：US15477584
申请日：2017-04-03
申请人： ChroMedX Corp.
发明人： James Samsoondar
IPC分类号： G01N1/40 , B01D61/22 , G01N35/10 , G01N35/00 , G01N35/02 , B01D61/14 , B01D63/02
CPC分类号： G01N1/4077 , B01D61/145 , B01D61/20 , B01D61/22 , B01D63/02 , B01D65/02 , B01D2313/16 , B01D2313/44 , B01D2313/58 , B01D2321/04 , B01L3/0237 , B01L3/0279 , B01L2300/0663 , B01L2300/0681 , B01L2400/0478 , G01N33/491 , G01N33/74 , G01N33/94 , G01N35/00732 , G01N35/00871 , G01N35/026 , G01N35/1011 , G01N35/1083 , G01N2001/4088 , G01N2035/00475 , G01N2035/00752 , G01N2035/00801 , G01N2035/00811 , G01N2035/1013 , G01N2035/103 , G01N2035/1053
摘要： The present invention provides a disposable ultra-filtration system comprising a disposable pipetting tip and a disposable ultra-filtration cartridge, wherein the cartridge includes a membrane filtration chamber and a dead-end channel. In use, a piston in the pipette pressurizes air within the channel; the pressurized air can subsequently move the piston and cause a reverse flow back through the membrane of the cartridge, unplugging the pores thereof. Also disclosed is an automated workstation incorporating the disposable ultra-filtration system, and a system comprising the automated workstation, useful for measuring the free therapeutic drug concentration and free hormone concentration in a sample.

7. 发明专利

CA2978737C POINT-OF-CARE TESTING SYSTEM FOR BLOOD GASES AND CO-OXIMETRY 未知
公开(公告)号：CA2978737C
公开(公告)日：2018-10-02
申请号：CA2978737
申请日：2017-03-27
申请人： CHROMEDX CORP
发明人： SAMSOONDAR JAMES
IPC分类号： G01N33/84 , A61J1/20 , G01N33/49
摘要： A cartridge and system involving a joint spectroscopic and biosensor blood analyzer for measurement of at least two hemoglobin species in a patient's blood sample by spectroscopy, and measurement of at least pH of the blood sample by biosensor, for assessing the patient's oxygenation and acid-base status. The cartridge comprises a housing having a first housing member and a second housing member bonded together by a gasket. The housing comprises a cartridge inlet; a blood storage conduit; an optical chamber; a biosensor conduit ; a waste receptacle; a vent; an air bladder, an air bladder exit port; and, an optical window and an aligned optical member, the aligned optical member being one of a reflecting member or a second optical window, and being positioned to align with at least a portion of the optical chamber and at least a portion of the optical window.

8. 发明专利

CA2911318A1 JOINT SPECTROSCOPIC AND BIOSENSOR SYSTEM FOR POINT-OF-CARE TESTING 未知
公开(公告)号：CA2911318A1
公开(公告)日：2015-11-30
申请号：CA2911318
申请日：2015-05-20
申请人： CHROMEDX CORP
发明人： SAMSOONDAR JAMES
IPC分类号： G01N21/25 , G01N33/49
摘要： Some embodiments of the invention provide a system for measurement of at least two hemoglobin species in a patient's blood sample by spectroscopy, and measurement of at least pH of the blood sample by biosensor. The system comprises a disposable cartridge adapted for insertion into a slot of an analyzer, and the results are used to monitor the acid-base status of a patient. A method for monitoring the acid-base status of a patient using the system is also provided.

9. 发明专利

ES2692094T3 Sistema automatizado de ultrafiltración 未知
公开(公告)号：ES2692094T3
公开(公告)日：2018-11-30
申请号：ES13859916
申请日：2013-12-06
申请人： CHROMEDX CORP
发明人： SAMSOONDAR JAMES
IPC分类号： B01D61/18 , B01D27/00 , B01D35/02 , B01L3/02 , G01N1/34 , G01N33/15 , G01N35/10
摘要： Una estación de trabajo automatizada (100) para preparar un ultrafiltrado en uno o más aparatos de ultrafiltración desechables, comprendiendo la estación de trabajo automatizada (100): un controlador (170); uno o más soportes de cartuchos (140) para mantener uno o más cartuchos de ultrafiltración desechables (20, 40, 50, 142) del uno o más aparatos de ultrafiltración desechables; una o más gradillas de tubos de ensayo (150) para mantener uno o más tubos de ensayo (152); uno o más soportes de puntas de pipeteo (120) para mantener una o más puntas de pipeteo desechables (70, 122) del uno o más aparatos de ultrafiltración desechables, comprendiendo cada punta de pipeteo desechable (70, 122) una punta de pipeteo de desplazamiento positivo que tiene un pistón (87); una base (200), comprendiendo la base posiciones de soporte de cartuchos para colocar el uno o más soportes de cartuchos (140) en ubicaciones predeterminadas, posiciones de gradilla de tubos de ensayo para colocar la una o más gradillas de tubos de ensayo (150) en ubicaciones predeterminadas, y posiciones de soporte de puntas de pipeteo para colocar el uno o más soportes de punta de pipeteo (120) en ubicaciones predeterminadas; detectores de soportes de cartuchos para detectar la presencia de un soporte de cartuchos (140) del uno o más soportes de cartuchos (140) en la base (200) en las ubicaciones predeterminadas, teniendo los detectores de soportes de cartuchos un elemento de salida para señalar al controlador (170) la presencia del soporte de cartuchos (140); detectores de gradillas de tubos de ensayo para detectar la presencia de una gradilla de tubos de ensayo (150) de la una o más gradillas de tubos de ensayo (150) en la base (200) en las ubicaciones predeterminadas, los detectores de gradilla de tubos de ensayo tienen un elemento de salida para señalar al controlador (170)la presencia de la gradilla de tubos de ensayo (150); detectores de soporte de puntas de pipeteo para detectar la presencia de un soporte de puntas de pipeteo (120) del uno o más soportes de puntas de pipeteo (120) en la base (200) en las ubicaciones predeterminadas, teniendo los detectores de soporte de puntas de pipeteo un elemento de salida para señalar al controlador (170)la presencia del soporte de puntas de pipeteo (120); una herramienta de pipeteo (110) que comprende dedos elásticos que se abren radialmente al moverse en contra de una fuerza ejercida por un resorte para agarrar un pistón de punta de pipeteo que sujeta una varilla (89) de la una o más puntas de pipeteo desechables (70, 122); un brazo móvil (114), soportado a partir de la base (200), soportando el brazo móvil (114) la herramienta de pipeteo (110); y un recipiente para desechos (160) para recibir la una o más puntas de pipeteo desechables (70, 122) liberadas por la herramienta de pipeteo (110).

10. 发明专利

CA2978737A1 POINT-OF-CARE TESTING SYSTEM FOR BLOOD GASES AND CO-OXIMETRY 未知
公开(公告)号：CA2978737A1
公开(公告)日：2017-10-01
申请号：CA2978737
申请日：2017-03-27
申请人： CHROMEDX CORP
发明人： SAMSOONDAR JAMES
IPC分类号： G01N33/84 , A61J1/20 , G01N33/49
摘要： A cartridge and system involving a joint spectroscopic and biosensor blood analyzer for measurement of at least two hemoglobin species in a patient's blood sample by spectroscopy, and measurement of at least pH of the blood sample by biosensor, for assessing the patient's oxygenation and acid-base status. The cartridge comprises a housing having a first housing member and a second housing member bonded together by a gasket. The housing comprises a cartridge inlet; a blood storage conduit; an optical chamber; a biosensor conduit ; a waste receptacle; a vent; an air bladder, an air bladder exit port; and, an optical window and an aligned optical member, the aligned optical member being one of a reflecting member or a second optical window, and being positioned to align with at least a portion of the optical chamber and at least a portion of the optical window.

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