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1. 发明申请

WO2022240674A1 OPTICAL ANALYZER ASSEMBLY WITH SAFETY SHUTDOWN SYSTEM FOR INTRAVASCULAR LITHOTRIPSY DEVICE 审中-公开
公开(公告)号：WO2022240674A1
公开(公告)日：2022-11-17
申请号：PCT/US2022/028035
申请日：2022-05-06
申请人： BOLT MEDICAL, INC.
发明人： COOK, Christopher, A. , SCHULTHEIS, Eric , TROUTMAN, Rachel, Lynn , SWIFT, James, Dee
IPC分类号： A61B18/26 , A61B2017/00061 , A61B2018/0022 , A61B2018/00345 , A61B2018/00369 , A61B2018/00577 , A61B2018/00642 , A61B2018/00678 , A61B2018/00708 , A61B2018/00785 , A61B2018/00898 , A61B2018/00982 , A61B2018/2247 , A61B2018/263 , A61B2018/266
摘要： A catheter system (200) for treating a treatment site (106) within or adjacent to a vessel wall (108A) or a heart valve, includes a light source (224), a balloon (104), a light guide (222A) and an optical analyzer assembly (242). The light source (224) generates first light energy (224B). The balloon (104) is positionable substantially adjacent to the treatment site (106). The balloon (104) has a balloon wall (130) that defines a balloon interior (146) that receives a balloon fluid (132). The light guide (222A) receives the first light energy (224B) and guides the first light energy (224B) in a first direction (121F) from a guide proximal end (222P) toward a guide distal end (222D) positioned within the balloon interior (146). The optical analyzer assembly (242) optically analyzes a second light energy (224C) from the light guide (222A) that moves in a second direction (121S) that is opposite the first direction. The optical analyzer assembly (242) includes a safety shutdown system (283) to inhibit the first light energy (224B) from being received by the guide proximal end (222P) of the light guide (222A).

2. 发明申请

WO2022187058A1 VALVULOPLASTY TREATMENT ASSEMBLY AND METHOD USING DIRECTED BUBBLE ENERGY 审中-公开
公开(公告)号：WO2022187058A1
公开(公告)日：2022-09-09
申请号：PCT/US2022/017562
申请日：2022-02-23
申请人： BOLT MEDICAL, INC.
发明人： SCHULTHEIS, Eric
IPC分类号： A61B18/24 , A61B18/26 , A61B17/22
摘要： A catheter system (100) for treating a treatment site (106) within or adjacent to the heart valve (108) within a body (107) of a patient (109) includes an energy source (124), an energy guide (122A) and an energy director (104B). The energy source (124) generates energy. The energy guide (122A) includes a guide proximal end (122P) and a guide distal end (122D). The energy guide (122 A) is configured to receive energy from the energy source (124) and guide the energy from the guide proximal end (122P) toward the guide distal end (122D). The energy director (104B) includes a director wall (130) that defines a director interior (146), and a director distal end (104D) that is selectively positioned substantially adjacent to the treatment site (106). The guide distal end (122D) of the energy guide (122A) is positioned within the director interior (146). The director distal end (104D) is at least partially open in a direction toward the treatment site (106).

3. 发明申请

WO2021126762A1 MULTIPLEXER FOR LASER-DRIVEN LITHOPLASTY DEVICE 审中-公开
公开(公告)号：WO2021126762A1
公开(公告)日：2021-06-24
申请号：PCT/US2020/064846
申请日：2020-12-14
申请人： BOLT MEDICAL, INC.
发明人： COOK, Christopher, A. , BACHER, Gerald, D. , SCHULTHEIS, Eric , MOSSAYEBI, Mina , XIE, Wenjie , LIU, Yu
IPC分类号： A61B18/24 , A61B18/26 , A61B18/245 , A61B2018/0022 , A61B2018/00386 , A61B2018/00422 , A61B2018/2211 , A61B2018/263 , A61B2018/266 , G02B27/283 , G02B6/4213 , G02B6/4214
摘要： A catheter system (100) for treating a vascular lesion (106 A) within or adjacent to a vessel wall (108 A) within a body (107) of a patient (109) includes a single light source (124) that generates light energy, a first light guide (122 A) and a second light guide (122A), and a multiplexer (128). The first light guide (122A) and the second light guide (122A) are each configured to selectively receive light energy from the light source (124). The multiplexer (128) receives the light energy from the light source (124) in the form of a source beam (124 A) and selectively directs the light energy from the light source (124) in the form of individual guide beams (124B) to each of the first light guide (122 A) and the second light guide (122A).

4. 发明申请

WO2021101766A1 ENERGY MANIFOLD FOR DIRECTING AND CONCENTRATING ENERGY WITHIN A LITHOPLASTY DEVICE 审中-公开
公开(公告)号：WO2021101766A1
公开(公告)日：2021-05-27
申请号：PCT/US2020/059960
申请日：2020-11-11
申请人： BOLT MEDICAL, INC.
发明人： COOK, Christopher, A. , SCHULTHEIS, Eric
IPC分类号： A61B18/04 , A61B18/24 , A61B18/26
摘要： A catheter system (100) for treating a vascular lesion (106A) within or adjacent to a vessel wall (108A) within a body (107) of a patient (109) includes a catheter fluid (132), an energy source (124) that generates energy, an energy guide (122A) and an energy manifold (129). The energy guide (122A) includes a guide distal end (122D) that is selectively positioned near the vascular lesion (106A). The energy guide (122A) is configured to receive energy from the energy source (124) and generate a plasma bubble (134) within the catheter fluid (132). The energy manifold (129) is coupled to the energy guide (122A) near the guide distal end (122D). The energy manifold (129) includes (i) a manifold body (260) that defines a body chamber (266), the body chamber (266) being configured to retain at least some of the catheter fluid (132), and (ii) a manifold aperture (262) that extends through the manifold body (260). The energy manifold (129) directs energy from the plasma bubble (134) out of the body chamber (266) through the manifold aperture (262) and toward the vascular lesion (106A).

5. 发明申请

WO2021086571A1 ASYMMETRICAL BALLOON FOR LITHOPLASTY DEVICE 审中-公开
公开(公告)号：WO2021086571A1
公开(公告)日：2021-05-06
申请号：PCT/US2020/054792
申请日：2020-10-08
申请人： BOLT MEDICAL, INC.
发明人： SCHULTHEIS, Eric
IPC分类号： A61B18/26 , A61B18/14
摘要： A catheter system (100) for treating a treatment site (106) within or adjacent to a vessel wall (108A) within a body (107) of a patient (109) includes an energy source (124), a balloon (104), and an energy guide (122A). The energy source (124) generates energy. The balloon (104) includes a balloon wall (130) that defines a balloon interior (146). The balloon (104) is configured to retain a balloon fluid (132) within the balloon interior (146). The balloon (104) is selectively inflatable with the balloon fluid (132) to expand to an inflated state wherein the balloon wall (130) is positionable substantially adjacent to the treatment site (106). The balloon (104) further includes a balloon central axis (260) that extends through a geometric center (204C) of the balloon (104) when the balloon (104) is in the inflated state. The energy guide (122A) selectively receives energy from the energy source (124) and guides the energy from the energy source (124) into the balloon interior (146). The energy guide (122A) includes a guide distal end (122D) that is positioned on the balloon central axis (260) when the balloon (104) is in the inflated state.

6. 发明申请

WO2022260932A1 ACTIVE ALIGNMENT SYSTEM FOR LASER OPTICAL COUPLING 审中-公开
公开(公告)号：WO2022260932A1
公开(公告)日：2022-12-15
申请号：PCT/US2022/032045
申请日：2022-06-03
申请人： BOLT MEDICAL, INC.
发明人： COOK, Christopher, A.
IPC分类号： A61B18/24
摘要： A catheter system (100) for treating a treatment site (106) within or adjacent to a vessel wall (1 OSA) or a heart valve includes a light source (124), a first light guide (122A), a second light guide (122A), and an optical alignment system (257). The light source (124) generates light energy (224A, 224B, 324A, 324B, 424B). The first light guide (122A) receives the light energy (224A, 224B, 324A, 324B, 424B) from the light source (124). The first light guide (122A) has a guide proximal end (122P). The second light guide (122A) receives the light energy (224A, 224B, 324A, 324B, 424B) from the light source (124). The second light guide (122A) has a guide proximal end (122P). A multiplexer (223) directs the light energy (224A, 224B, 324A, 324B, 424B) toward the guide proximal end (122P) of the first light guide (122A) and the guide proximal end (122P) of the second light guide (122A). The optical alignment system (257) determines an alignment of the light energy (224A, 224B, 324A, 324B, 424B) relative to at least one of the guide proximal ends (122P). The optical alignment system (257) adjusts the positioning of the light energy (224A, 224B, 324A, 324B, 424B) relative to the at least one of the guide proximal ends (122P) based at least partially on the alignment of the light energy (224A, 224B, 324A, 324B, 424B) relative to the at least one of the guide proximal ends (122P).

7. 发明申请

WO2021202248A1 ELECTRICAL ANALYZER ASSEMBLY FOR INTRAVASCULAR LITHOTRIPSY DEVICE 审中-公开
公开(公告)号：WO2021202248A1
公开(公告)日：2021-10-07
申请号：PCT/US2021/024216
申请日：2021-03-25
申请人： BOLT MEDICAL, INC.
发明人： SCHULTHEIS, Eric , BACHER, Gerald D.
IPC分类号： A61B18/26 , A61B18/04 , A61B18/14 , A61B90/00 , A61N1/05 , A61B18/00 , A61B18/12 , A61B18/042 , A61B18/1492 , A61B18/245 , A61B2017/00026 , A61B2017/00039 , A61B2017/00154 , A61B2018/0022 , A61B2018/00345 , A61B2018/00369 , A61B2018/00386 , A61B2018/00422 , A61B2018/00642 , A61B2018/00708 , A61B2018/00875 , A61B2018/00898 , A61B2018/1213 , A61B2018/263 , A61B2018/266 , A61B2090/0809 , A61N1/057
摘要： A catheter system (100) for treating a treatment site (106) within or adjacent to a vessel wall (108) or heart valve includes an energy source (124), an inflatable balloon (104), an energy guide (122 A), and an electrical analyzer assembly (142). The energy source (124) generates energy. The inflatable balloon (104) is positionable substantially adjacent to the treatment site (106). The inflatable balloon (104) has a balloon wall (130) that defines a balloon interior (146). The balloon interior (146) receives a balloon fluid (132). The energy guide (122A) is configured to receive energy from the energy source (124) and guide the energy into the balloon interior (146). The electrical analyzer assembly (142) is configured to monitor a condition of the inflatable balloon (104) during use of the catheter system (100). The electrical analyzer assembly (142) includes a first electrode (158), a second electrode (160), and an impedance detector (162) that is electrically coupled to the first electrode (158) and the second electrode (160). The impedance detector (162) is configured to detect impedance between the first electrode (158) and the second electrode (160).

8. 发明申请

WO2021183367A1 LASER PULSE SHAPING TO ENHANCE CONVERSION EFFICIENCY AND PROTECT FIBER OPTIC DELIVERY SYSTEM FOR DISRUPTION OF VASCULAR CALCIUM 审中-公开
公开(公告)号：WO2021183367A1
公开(公告)日：2021-09-16
申请号：PCT/US2021/020937
申请日：2021-03-04
申请人： BOSTON SCIENTIFIC SCIMED, INC. , BOLT MEDICAL, INC.
发明人： MASSIMINI, Daniel , MCGOWAN, Roger , SHAO, Haiping , COOK, Christopher, A.
IPC分类号： A61B18/26 , A61B18/24
摘要： A catheter system (100) includes a power source (124), a controller (123), and a light guide (122). The power source (124) generates a plurality of energy pulses (242B, 342B). The controller (123) controls the power source (124) so that the plurality of energy pulses (242B, 342A-B) cooperate to produce a composite energy pulse (348A-B, 448A-C, 548A-F) having a composite pulse shape. The light guide (122) receives the composite energy pulse (348A-B, 448A-C, 548A-F). The light guide (122) emits light energy in a direction away from the light guide (122) to generate a plasma pulse (246A-B, 346A-B) away from the light guide (122). The power source (124) can be a laser and the light guide (122) can be an optical fiber. Each of the energy pulses (242B, 342A-B) has a pulse width, and the energy pulses (242B, 342A-B) are added to one another so that the composite energy pulse (348A-B, 448A-C, 548A-F) has a pulse width that is longer than the pulse width of any one of the energy pulses (242B, 342A-B). At least two of the energy pulses (242B, 342A-B) can have the same wavelength as or a different wavelength from one another.

9. 发明申请

WO2020256949A1 PLASMA CREATION VIA NONAQUEOUS OPTICAL BREAKDOWN OF LASER PULSE ENERGY FOR BREAKUP OF VASCULAR CALCIUM 审中-公开
公开(公告)号：WO2020256949A1
公开(公告)日：2020-12-24
申请号：PCT/US2020/036107
申请日：2020-06-04
申请人： BOSTON SCIENTIFIC SCIMED, INC. , BOLT MEDICAL, INC
发明人： MASSIMINI, Daniel , McGOWAN, Roger , SHAO, Haiping , COOK, Christopher, A.
IPC分类号： A61B18/24 , A61B17/22 , A61B18/26 , A61B17/00 , A61B18/00
摘要： A catheter system (100) for treating a treatment site (106) within or adjacent to a blood vessel (108) includes a power source (124), a light guide (122) and a plasma target (242). In various embodiments, the light guide (122) receives power from the power source (124). The light guide (122) has a distal tip (244), and the light guide (122) emits light energy (243) in a direction away from the distal tip (244). The plasma target (242) is spaced apart from the distal tip (244) of the light guide (122) by a target gap distance (245). The plasma target (242) is configured to receive light energy (243) from the light guide (122) so that a plasma bubble (234) is generated at the plasma target (242). The power source (124) can be a laser and the light guide (122) can be an optical fiber. In certain embodiments, the catheter system (100) can also an inflatable balloon (104) that encircles the distal tip (244) of the light guide (122). The plasma target (242) can be positioned within the inflatable balloon (104). The target gap distance (245) can be greater than 1 μm. The plasma target (242) can have a target face (1672) that receives the light energy (243) from the light guide (122). The target face (1672) can be angled relative to a direction the light energy (243) is emitted to the plasma target (242). The plasma target (242) can be formed from one or more of tungsten, tantalum, platinum, molybdenum niobium, iridium, magnesium oxide, beryllium oxide, tungsten carbide, titanium nitride, titanium carbonitride and titanium carbide.

10. 发明申请

WO2022216488A1 INTRAVASCULAR LITHOTRIPSY BALLOON 审中-公开
公开(公告)号：WO2022216488A1
公开(公告)日：2022-10-13
申请号：PCT/US2022/022460
申请日：2022-03-30
申请人： BOLT MEDICAL, INC.
发明人： SCHULTHEIS, Eric , DUONG, Alan , WAGGONER, Thomas, E. , COOK, Christopher, A.
IPC分类号： A61B18/24 , A61B18/26
摘要： A catheter system (100) for treating a treatment site (106) within or adjacent to a vessel wall (108) or heart valve includes a balloon (104) having a balloon length (204L). The balloon (104) is configured to be movable between an inflated state (135) and a deflated state. The balloon (104) includes (i) a balloon proximal region (250), (ii) a balloon distal region (254), and (iii) a balloon transition region (252). The balloon proximal region (250) has a balloon proximal end (204P) and a substantially constant balloon proximal region diameter (256) while the balloon (104) is in the inflated state (135). The balloon distal region (254) has a balloon distal end (104D), and a substantially constant balloon distal region diameter (262) while the balloon (104) is in the inflated state (135). The balloon distal region diameter (262) is different than the balloon proximal region diameter (256). The balloon transition region (252) has a balloon transition region diameter (260) that varies. The balloon transition region (252) is positioned between the balloon proximal region (250) and the balloon distal region (254).

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