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1. 发明专利

JP2019535630A 半透明ナノ結晶ガラスセラミック审中-公开
公开(公告)号：JP2019535630A
公开(公告)日：2019-12-12
申请号：JP2019525976
申请日：2017-11-16
申请人：アドゥロ・マテリアル・アクチボラゲット , ADURO MATERIAL AB
发明人：ホーカン・エングクヴィスト , ルァ・フー , ウェイ・シア
IPC分类号： C03C14/00 , C04B35/624 , C04B35/626 , C04B35/645 , A61K6/02 , A61K6/027 , C03B8/02
摘要：本発明は、超高曲げ強度を有する半透明ZrO 2 −SiO 2 ナノ結晶ガラスセラミック(NCGC)を生産する材料組成物及び方法を提供する。この方法は、以下の工程を含む。(1)ゾル−ゲル法によって、高純度の均質なZrO 2 −SiO 2 ナノサイズ粉末を調製する。(2)ZrO 2 −SiO 2 ナノサイズのゾル−ゲル粉末の加圧焼結により、半透明のZrO 2 −SiO 2 NCGCを得る。本発明はまた、その方法を用いて製造された材料も含む。

2. 发明申请

WO2021177882A1 FORMULATION COMPRISING CALCIUM SILICATE 审中-公开
公开(公告)号：WO2021177882A1
公开(公告)日：2021-09-10
申请号：PCT/SE2021/050180
申请日：2021-03-02
申请人： ADURO MATERIAL AB
发明人： ENGQVIST, Håkan
IPC分类号： A61Q3/02 , A61Q5/12 , A61K8/04 , A61K8/25 , A61Q19/08 , A61K33/06
摘要： Calcium and silicon are known to strengthen the formation of hair, skin and nails. The efficacy of oral intake of calcium and silicon is very difficult. Local delivery and uptake of the ions would enable more efficient strengthening of 5 nails, skin or hair. The invention relates to the addition of calcium silicate to products for local release of calcium and silicate to nails, hair and skin.

3. 发明申请

WO2023018366A1 CONTROLLED DRUG RELEASE MATERIAL 审中-公开
公开(公告)号：WO2023018366A1
公开(公告)日：2023-02-16
申请号：PCT/SE2022/050722
申请日：2022-07-18
申请人： ADURO MATERIAL AB
发明人： ENGQVIST, Håkan
IPC分类号： A61K47/04 , A61K9/14 , A61K31/17 , A61P31/00
摘要： The present invention relates to pharmaceutical compositions comprising an inorganic salt and hydroxyurea or a pharmaceutically acceptable salt thereof. The composition is in the form of doped crystals so that the hydroxyurea, or the pharmaceutically acceptable salt thereof, is included in the crystal lattice of the inorganic salt. The invention also relates to use of a pharmaceutical composition according to the invention as a medicament.

4. 发明申请

WO2010093285A8 COMPOSITION COMPRISING BIODEGRADABLE CARRIER FOR CONTROLLED DRUG DELIVERY 审中-公开
标题翻译：包含用于控制药物递送的生物可降解载体的组合物
公开(公告)号：WO2010093285A8
公开(公告)日：2010-09-30
申请号：PCT/SE2009000080
申请日：2009-02-12
申请人： ADURO MATERIAL AB , ENGQVIST HAAKAN
发明人： ENGQVIST HAAKAN
IPC分类号： A61K47/04 , A61K9/14 , A61K9/22
CPC分类号： A61K9/2095 , A61K9/0019 , A61K9/145 , A61K9/2013
摘要： The present invention relates to a controlled release medical composition comprising: a powder composition of a binder; a water based liquid; and a medical active pharmaceutical ingredient. In a first embodiment the powder composition comprises at least calcium carbonate of a first phase and calcium carbonate of a second different phase, the first and second phase are selected from the group: amorphous calcium carbonate; vaterite; aragonite; and calcite; and in a second embodiment the powder composition comprises calcium carbonate, or calcium sulphate, or calcium phosphate, or combinations thereof.
摘要翻译：本发明涉及控释药物组合物，其包含：粘合剂的粉末组合物; 一种水基液体; 和医药活性药物成分。在第一实施方案中，粉末组合物至少包含第一相的碳酸钙和第二不同相的碳酸钙，第一相和第二相选自无定形碳酸钙; 球霰石; 文石; 和方解石; 并且在第二实施方案中，粉末组合物包含碳酸钙或硫酸钙或磷酸钙或其组合。

5. 发明申请

WO2018093322A1 TRANSLUCENT NANOCRYSTALLINE GLASS CERAMIC 审中-公开
公开(公告)号：WO2018093322A1
公开(公告)日：2018-05-24
申请号：PCT/SE2017/051135
申请日：2017-11-16
申请人： ADURO MATERIAL AB , XIA, Wei
发明人： XIA, Wei , ENGQVIST, Håkan , FU, Le
IPC分类号： C03C10/00
摘要： The present invention provides a material composition and a process of producing translucent ZrO 2 -SiO 2 nanocrystalline glass ceramic (NCGC) with ultra-high flexural strength. The method comprises the following step: (1) prepare homogenous ZrO2-SiO2 nano-sized powder with high purity via a sol-gel method; (2) pressure assisted sintering of ZrO2-SiO2 nano-sized sol-gel powder to obtain translucent ZrO2-SiO2 NCGC. The invention also includes materials manufactured using the method.

6. 发明申请

WO2016005822A1 CEMENT SYSTEMS, HARDENED CEMENTS AND IMPLANTS 审中-公开
标题翻译：水泥系统，硬化材料和植入物
公开(公告)号：WO2016005822A1
公开(公告)日：2016-01-14
申请号：PCT/IB2015/001800
申请日：2015-07-07
申请人： ADURO MATERIAL AB
发明人： ENGQVIST, Håkan
IPC分类号： A61K6/083 , A61K6/06
CPC分类号： A61C8/0015 , A61C5/73 , A61C13/09 , A61K6/0606 , A61K6/0612 , A61K6/0631 , A61K6/0675 , A61K6/0835 , C04B14/043 , C04B14/36 , C04B28/04 , C04B2111/00836 , C08L33/00
摘要： A cement system for forming an implant comprises a reactive glass ionomer cement (GIC) powder, a polycarboxylic acid or salt, and a filler. The polycarboxylic acid or salt is included to initially provide a paste having a pH less than 7 when the cement system is mixed with water. In one embodiment, the filler is substantially inert when mixed with water and is selected from (CaO)(AI 2 O 3 )6, (CaO)(AI 2 O 3 ) 2 , calcium silicate (CaOSiO 2 ), and mixtures thereof. In another embodiment, the filler is substantially reactive when mixed with water and is selected from (CaO) 2 (SiO 2 ), (CaO) 3 (SiO 2 ), and mixtures thereof, and the cement system includes an additional acid to maintain the paste at a pH less than 7 for at least one hour after the cement system is mixed with water.
摘要翻译：用于形成植入物的水泥系统包括反应性玻璃离聚物粘固剂（GIC）粉末，多元羧酸或盐和填料。包含多元羧酸或盐以最初提供当水泥体系与水混合时pH小于7的糊料。在一个实施方案中，当与水混合时，填料基本上是惰性的，并且选自（CaO）（Al 2 O 3）6，（CaO）（Al 2 O 3）2，硅酸钙（CaOSiO 2）及其混合物。在另一个实施方案中，当与水混合时，填料基本上具有反应性，并且选自（CaO）2（SiO 2），（CaO）3（SiO 2）及其混合物，并且该水泥体系包括另外的酸以将糊保持在在水泥体系与水混合至少一小时后，pH小于7。

7. 发明申请

WO2010093285A1 COMPOSITION COMPRISING BIODEGRADABLE CARRIER FOR CONTROLLED DRUG DELIVERY 审中-公开
标题翻译：包含用于控制药物递送的生物可降解载体的组合物
公开(公告)号：WO2010093285A1
公开(公告)日：2010-08-19
申请号：PCT/SE2009/000080
申请日：2009-02-12
申请人： ADURO MATERIAL AB , ENGQVIST, Häkan
发明人： ENGQVIST, Häkan
IPC分类号： A61K47/04 , A61K9/14 , A61K9/22
CPC分类号： A61K9/2095 , A61K9/0019 , A61K9/145 , A61K9/2013
摘要： The present invention relates to a controlled release medical composition comprising: a powder composition of a binder; a water based liquid; and a medical active pharmaceutical ingredient. In a first embodiment the powder composition comprises at least calcium carbonate of a first phase and calcium carbonate of a second different phase, the first and second phase are selected from the group: amorphous calcium carbonate; vaterite; aragonite; and calcite; and in a second embodiment the powder composition comprises calcium carbonate, or calcium sulphate, or calcium phosphate, or combinations thereof.
摘要翻译：本发明涉及一种控释药物组合物，其包含：粘合剂的粉末组合物; 水基液体; 和医药活性药物成分。在第一实施方案中，粉末组合物至少包含第一相的碳酸钙和第二不同相的碳酸钙，第一相和第二相选自无定形碳酸钙; 球霰石; 文石; 和方解石; 并且在第二实施方案中，粉末组合物包含碳酸钙或硫酸钙或磷酸钙，或其组合。

8. 发明申请

US20110313052A1 Composition Comprising Biodegradable Carrier for Controlled Delivery 审中-公开
标题翻译：包含用于受控输送的生物降解载体的组合物
公开(公告)号：US20110313052A1
公开(公告)日：2011-12-22
申请号：US13148686
申请日：2009-02-12
申请人： Håkan Engqvist
发明人： Håkan Engqvist
IPC分类号： A61K47/02 , B02C9/04
CPC分类号： A61K9/2095 , A61K9/0019 , A61K9/145 , A61K9/2013
摘要： The present invention relates to a controlled release medical composition comprising: a powder composition of a binder; a water based liquid; and a medical active pharmaceutical ingredient. In a first embodiment the powder composition comprises at least calcium carbonate of a first phase and calcium carbonate of a second different phase, the first and second phase are selected from the group: amorphous calcium carbonate; vaterite; aragonite; and calcite; and in a second embodiment the powder composition comprises calcium carbonate, or calcium sulphate, or calcium phosphate, or combinations thereof.
摘要翻译：本发明涉及一种控释药物组合物，其包含：粘合剂的粉末组合物; 水基液体; 和医药活性药物成分。在第一实施方案中，粉末组合物至少包含第一相的碳酸钙和第二不同相的碳酸钙，第一相和第二相选自无定形碳酸钙; 球霰石文石和方解石; 并且在第二实施方案中，粉末组合物包含碳酸钙或硫酸钙或磷酸钙，或其组合。

9. 发明申请

US20230121379A1 FORMULATION COMPRISING CALCIUM SILICATE 有权
公开(公告)号：US20230121379A1
公开(公告)日：2023-04-20
申请号：US17908437
申请日：2021-03-02
申请人： ADURO MATERIAL AB
发明人： Håkan ENGQVIST
IPC分类号： A61K8/25 , A61Q3/02 , A61Q5/12 , A61Q19/00
摘要： Calcium and silicon are known to strengthen the formation of hair, skin and nails. The efficacy of oral intake of calcium and silicon is very difficult. Local delivery and uptake of the ions would enable more efficient strengthening of 5 nails, skin or hair. The invention relates to the addition of calcium silicate to products for local release of calcium and silicate to nails, hair and skin.

10. 发明授权

US11142478B2 Translucent nanocrystalline glass ceramic 有权
公开(公告)号：US11142478B2
公开(公告)日：2021-10-12
申请号：US16461321
申请日：2017-11-16
申请人： ADURO MATERIAL AB
发明人： Håkan Engqvist , Le Fu , Wei Xia
IPC分类号： C03C10/00 , A61K6/818 , A61K6/833 , C03C12/00 , A61C13/083 , C03B19/06
摘要： The present invention provides a material composition and a process of producing translucent ZrO2—SiO2 nanocrystalline glass ceramic (NCGC) with ultra-high flexural strength. The method comprises the following step: (1) prepare homogenous ZrO2-SiO2 nano-sized powder with high purity via a sol-gel method; (2) pressure assisted sintering of ZrO2-SiO2 nano-sized sol-gel powder to obtain translucent ZrO2-SiO2 NCGC. The invention also includes materials manufactured using the method.

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