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1. 发明申请

US20110248381A1 Multilayer Memristive Devices 有权
标题翻译：多层记忆装置
公开(公告)号：US20110248381A1
公开(公告)日：2011-10-13
申请号：US13130815
申请日：2009-01-20
申请人： William Tong , Nathaniel J. Quitoriano , Duncan Stewart , Philip J. Kuekes
发明人： William Tong , Nathaniel J. Quitoriano , Duncan Stewart , Philip J. Kuekes
IPC分类号： H01L29/86 , H01L21/02
CPC分类号： H01L21/26586 , H01L45/08 , H01L45/1233 , H01L45/14 , H01L45/145 , H01L45/146 , H01L45/147 , H01L45/165
摘要： A multilayer memristive device includes a first electrode (410); a second electrode (405); a first memristive region (430) and a second memristive region (435) which created by directional ion implantation of dopant ions (420, 425) and are interposed between the first electrode (410) and the second electrode (405); and mobile dopants (315) which move within the first memristive region (430) and the second memristive region (435) in response to an applied electrical field.
摘要翻译：多层回忆装置包括第一电极（410）; 第二电极（405）; 通过定向离子注入掺杂剂离子（420,425）而形成并且介于第一电极（410）和第二电极（405）之间的第一忆阻区（430）和第二忆阻区（435）。以及响应于施加的电场在第一忆阻区（430）和第二忆阻区（435）内移动的移动掺杂剂（315）。

2. 发明申请

US20090246425A1 Systems And Methods For Auto-Aligning Members Bearing Correlated Patterns 审中-公开
标题翻译：自动对齐轴承相关模式的成员的系统和方法
公开(公告)号：US20090246425A1
公开(公告)日：2009-10-01
申请号：US12262068
申请日：2008-10-30
申请人： William Tong , Philip J. Kuekes , Duncan Stewart , Wei Wu , Michael Tan
发明人： William Tong , Philip J. Kuekes , Duncan Stewart , Wei Wu , Michael Tan
IPC分类号： B32B7/04 , B29C65/00 , B29C43/20
CPC分类号： G01B7/31 , Y10T156/1744
摘要： A method of aligning first and second mating surfaces includes: generating a random or pseudo-random function; convolving the random or pseudo-random function with a spread function to produce a correlated function; forming a pattern of bi-polar material on the first mating surface based on a quantization of the correlated function; and forming a complementary pattern of the bi-polar material on the second mating surface. The complementary patterns exert a force on each other toward a desired alignment of the first and second mating surfaces. A system includes a first member having a first correlated pattern of material disposed on a first mating surface; and a second member having a second correlated pattern of material disposed on a second mating surface, wherein the second correlated pattern is complementary to the first correlated pattern. The first and second correlated patterns interact to facilitate a desired alignment of the first and second members.
摘要翻译：对准第一和第二匹配表面的方法包括：产生随机或伪随机函数; 将随机或伪随机函数与扩展函数进行卷积以产生相关函数; 基于所述相关函数的量化，在所述第一配合表面上形成双极材料的图案; 以及在所述第二配合表面上形成所述双极材料的互补图案。互补图案相互朝向第一和第二配合表面的期望对准施加力。一种系统包括：第一构件，具有设置在第一配合表面上的材料的第一相关图案; 以及具有设置在第二配合表面上的材料的第二相关图案的第二构件，其中所述第二相关图案与所述第一相关图案互补。第一和第二相关图案相互作用以促进第一和第二构件的期望对准。

3. 发明申请

US20070252131A1 Method of interconnect formation using focused beams 有权
标题翻译：使用聚焦光束的互连形成方法
公开(公告)号：US20070252131A1
公开(公告)日：2007-11-01
申请号：US11413476
申请日：2006-04-28
申请人： William Tong , Duncan Stewart , R. Williams , Manish Sharma , Zhiyong Li , Gary Gibson
发明人： William Tong , Duncan Stewart , R. Williams , Manish Sharma , Zhiyong Li , Gary Gibson
IPC分类号： H01L29/06
CPC分类号： H01L21/76892 , H01L21/76823 , H01L23/5254 , H01L27/1052 , H01L2924/0002 , H01L2924/12044 , H01L2924/3011 , H01L2924/00
摘要： A method of forming an electrical interconnect, which includes a first electrode, an interlayer of a programmable material disposed over at least a portion of the first electrode, and a second electrode disposed over the programmable material at a non-zero angle relative to the first electrode. The interlayer includes a modified region having differing electrical properties than the rest of the interlayer, sandwiched at the junction of the first electrode and the second electrode. The interlayer may be exposed to a focused beam to form the modified region.
摘要翻译：一种形成电互连的方法，包括第一电极，设置在第一电极的至少一部分上的可编程材料的中间层，以及设置在可编程材料上的第二电极，相对于第一电极以非零角度电极。中间层包括夹在第一电极和第二电极的接合处的与中间层的其余部分不同的电特性的改性区域。中间层可以暴露于聚焦光束以形成改质区域。

4. 发明申请

US20060043626A1 Imprint lithography apparatus and method employing an effective pressure 有权
标题翻译：压印光刻设备和采用有效压力的方法
公开(公告)号：US20060043626A1
公开(公告)日：2006-03-02
申请号：US10931672
申请日：2004-09-01
申请人： Wei Wu , William Tong , Jun Gao , Carl Picciotto
发明人： Wei Wu , William Tong , Jun Gao , Carl Picciotto
IPC分类号： B29C59/02
CPC分类号： B82Y10/00 , B82Y40/00 , G03F7/0002
摘要： An imprint apparatus and method employ an effective pressure in imprint lithography. The imprint apparatus includes a compressible chamber that encloses an imprint mold having a mold pattern and a sample to be imprinted. The chamber is compressed to imprint the mold pattern on the sample. The mold is pressed against the sample with the effective pressure. The effective pressure is controlled by a selected ratio of a cavity area of the chamber to a contact area between the mold and the sample.
摘要翻译：压印设备和方法在压印光刻中采用有效压力。压印装置包括可压缩室，其包围具有模具图案和要印刷的样品的压印模具。压缩室以将模具图案压印在样品上。模具以有效的压力压在样品上。有效压力通过腔室的空腔面积与模具和样品之间的接触面积的选定比例来控制。

5. 发明申请

US20100278730A1 Non-Invasive Molecular Imaging of Cellular Histone Deacetylase Substrate Using Magnetic Resonance Spectroscopy (MRS) or Positron Emission Tomography (PET) 审中-公开
标题翻译：使用磁共振光谱（MRS）或正电子发射断层扫描（PET）的细胞组蛋白脱乙酰酶底物的非侵入性分子成像
公开(公告)号：US20100278730A1
公开(公告)日：2010-11-04
申请号：US12595281
申请日：2008-04-08
申请人： Sabrina Ronen , Juri Gelovani , William Tong , Mian Alauddin , Uday Mukhopadhyay , Madhuri Sankaranatayanapillai , Ashutosh Pal
发明人： Sabrina Ronen , Juri Gelovani , William Tong , Mian Alauddin , Uday Mukhopadhyay , Madhuri Sankaranatayanapillai , Ashutosh Pal
IPC分类号： A61K51/00 , A61B5/055 , C07C237/28
CPC分类号： A61K49/10 , A61K51/04 , C07D249/06
摘要： We disclose methods of detecting histone deacetylase activity in a mammal by administering to the mammal a compound comprising at least one atom having a nucleus detectable by magnetic resonance spectroscopy, wherein the compound is a substrate of histone deacetylase; and observing the compound or a cleavage product thereof in at least a portion of the body of the mammal by magnetic resonance spectroscopy (MRS). We also disclose methods of detecting histone deacetylase activity in a mammal by administering to the mammal a compound comprising at least one positron-emission-decaying radioisotope, wherein the compound is a substrate of histone deacetylase; and observing the compound or a cleavage product thereof in at least a portion of the body of the mammal by positron emission tomography (PET). We also disclose compounds useful as histone deacetylase substrates.
摘要翻译：我们公开了通过向哺乳动物施用包含至少一个具有可通过磁共振光谱法检测的核的原子的化合物，其中所述化合物是组蛋白脱乙酰酶的底物，来检测哺乳动物组蛋白脱乙酰酶活性的方法; 并通过磁共振光谱法（MRS）观察哺乳动物体内至少一部分的化合物或其裂解产物。我们还公开了通过向哺乳动物施用包含至少一种正电子发射衰减放射性同位素的化合物来检测哺乳动物中组蛋白脱乙酰酶活性的方法，其中该化合物是组蛋白脱乙酰酶的底物; 并通过正电子发射断层摄影（PET）观察哺乳动物身体的至少一部分中的化合物或其裂解产物。我们还公开了可用作组蛋白脱乙酰酶底物的化合物。

6. 发明申请

US20060180480A1 E-field induced ion selective molecular deposition onto sensor arrays 失效
标题翻译：电场诱导离子选择性分子沉积到传感器阵列上
公开(公告)号：US20060180480A1
公开(公告)日：2006-08-17
申请号：US11059258
申请日：2005-02-15
申请人： Sean Zhang , Zhiyong Li , Zhang-Lin Zhou , William Tong , R. Williams , Yong Chen
发明人： Sean Zhang , Zhiyong Li , Zhang-Lin Zhou , William Tong , R. Williams , Yong Chen
IPC分类号： G01F1/64 , G01N33/487 , G01N27/26
CPC分类号： G01N33/5308 , G01N33/5438 , G01N2430/00
摘要： A sensor array for sensing at least one of chemical moieties and biological moieties is provided. The sensor array comprises a plurality of working electrodes electrically associated with a reference electrode, each working electrode in combination with the reference electrode forming a transducer. Each working electrode is provided with a coating of a sensing element comprised of an ionizable moiety and a functional group sensitive to one of the chemical and/or biological moieties.
摘要翻译：提供了用于感测化学部分和生物部分中的至少一个的传感器阵列。传感器阵列包括与参考电极电连接的多个工作电极，每个工作电极与参考电极组合形成换能器。每个工作电极设置有由可电离部分和对化学和/或生物部分之一敏感的官能团组成的感测元件的涂层。

7. 发明授权

US08111143B2 Assembly for monitoring an environment 有权
标题翻译：监测环境的大会
公开(公告)号：US08111143B2
公开(公告)日：2012-02-07
申请号：US11117976
申请日：2005-04-29
申请人： William Tong , Geoffrey Lyon , Philip Kuekes , Zhiyong Li , Shih-Yuan Wang , R. Stanley Williams
发明人： William Tong , Geoffrey Lyon , Philip Kuekes , Zhiyong Li , Shih-Yuan Wang , R. Stanley Williams
IPC分类号： H04Q5/22
CPC分类号： G01D21/00 , H04Q9/00
摘要： An assembly for monitoring an environment includes a RFID tag and a sensing unit. The sensing unit is configured to be activated by a RF signal received by the RFID tag and to sense information regarding an environment.
摘要翻译：用于监测环境的组件包括RFID标签和感测单元。感测单元被配置为由RFID标签接收的RF信号激活并且感测关于环境的信息。

8. 发明申请

US20060197243A1 Nano-imprinted photonic crystal waveguide 失效
标题翻译：纳米压印光子晶体波导
公开(公告)号：US20060197243A1
公开(公告)日：2006-09-07
申请号：US11072657
申请日：2005-03-04
申请人： James Ellenson , Timothy Hostetler , William Tong
发明人： James Ellenson , Timothy Hostetler , William Tong
IPC分类号： B29D11/00 , B32B18/00 , G02B6/00 , G02B6/10
CPC分类号： G03F7/0002 , B29D11/00663 , B82Y10/00 , B82Y20/00 , B82Y40/00 , G02B6/1225
摘要： This invention relates to a method for forming a nano-imprinted photonic crystal waveguide, comprising the steps of: preparing an optical film on a substrate; preparing a template having a plurality of protrusions of less than 500 nm in length such that the protrusions are spaced a predetermined distance from each other; heating the film; causing the template to press against the heated film such that a portion of the film is deformed by the protrusions; separating the template from the film; and etching the film to remove a residual layer of the film to form a nano-imprinted photonic crystal waveguide. Another embodiment of this invention fulfills these needs by providing a method for forming a nano-imprinted photonic crystal waveguide, comprising the steps of: a method for forming a nano-imprinted photonic crystal waveguide, comprising the steps of: preparing an optical film upon a substrate; preparing a template having a plurality of protrusions of less than 500 nm in length such that the protrusions are spaced a predetermined distance from each other; causing the template to modify a shape of the film; applying a UV light to the film and the template such that the film becomes polymerized; separating the template from the film; and etching the film to remove a residual layer of the film to form a nano-imprinted photonic crystal waveguide.
摘要翻译：本发明涉及一种形成纳米压印光子晶体波导的方法，包括以下步骤：在衬底上制备光学膜; 制备具有长度小于500nm的多个突起的模板，使得突起彼此间隔预定距离; 加热薄膜; 使得模板压靠加热的膜，使得膜的一部分由突起变形; 将模板与胶片分开; 并蚀刻该膜以除去该膜的残留层以形成纳米压印的光子晶体波导。本发明的另一实施例通过提供形成纳米压印光子晶体波导的方法来满足这些需要，包括以下步骤：形成纳米压印光子晶体波导的方法，包括以下步骤：在基质; 制备具有长度小于500nm的多个突起的模板，使得突起彼此间隔预定距离; 导致模板修改胶片的形状; 对膜和模板施加UV光使得膜变得聚合; 将模板与胶片分开; 并蚀刻该膜以除去该膜的残留层以形成纳米压印的光子晶体波导。

9. 发明申请

US20120002267A1 Individually Addressable Nano-Scale Mechanical Actuators 有权
标题翻译：单独寻址纳米级机械执行机构
公开(公告)号：US20120002267A1
公开(公告)日：2012-01-05
申请号：US13256256
申请日：2009-06-30
申请人： Jianhua Yang , R. Stanley William , William Tong
发明人： Jianhua Yang , R. Stanley William , William Tong
IPC分类号： G02B26/00
CPC分类号： F03G7/005
摘要： An addressable nano-scale mechanical actuator is formed at the intersection of two nanowires. The actuator has an active region disposed between the two nanowires, which form the electrodes of the actuator. The active region contains an electrolytically decomposable material. When an activation voltage is applied to the electrodes, the material releases a gas that forms a bubble at one electrode, causing a bulging of a top surface of the actuator. The bulging may be used, via mechanical coupling, to provide mechanical actuation on a nanometer scale. The nanowires may be arranged in a two-dimensional array to provide an array of individually addressable actuators.
摘要翻译：在两个纳米线的交叉处形成可寻址的纳米级机械致动器。致动器具有设置在两个纳米线之间的有源区域，其形成致动器的电极。活性区域含有电解质的材料。当激活电压施加到电极时，材料释放在一个电极处形成气泡的气体，导致致动器的顶表面膨胀。可以通过机械耦合使用凸起来提供纳米尺度的机械致动。纳米线可以被布置成二维阵列以提供单独可寻址致动器的阵列。

10. 发明申请

US20090170131A1 Agents for Imaging Apoptosis 审中-公开
标题翻译：成像细胞凋亡剂
公开(公告)号：US20090170131A1
公开(公告)日：2009-07-02
申请号：US12298386
申请日：2007-05-09
申请人： Juri Gelovani , William Tong , Amer Najjar , Chun Li
发明人： Juri Gelovani , William Tong , Amer Najjar , Chun Li
IPC分类号： G01N33/53
CPC分类号： C12Q1/37 , A61K47/556 , A61K51/04 , G01N2333/96466 , G01N2510/00
摘要： Compositions, and methods of using such compositions, having the following Formula (I) or salt, ester, or hydrate thereof, wherein R1 is Asp-Glu peotide, tert-butyloxycarbonyl, methoxyphenylacetyl, bromomethoxyphenylaceityl, fluoromethoxyphenylacetyl, (methylmethoxyphenyl)acetyl, or iodomethoxyphenylacetyl; R2 is valine with or without protecting groups), aspartale (with or without protecting groups), 1-Butyl, hydrogen, aniline, aromatic molecules, tert-butyloxycarbonyl, or fluorenyl-methoxy-carbonyl; and R3 is p-nitroaniline, 7-amino-4-methylcoumarin, fluoroethylamine, 1-amino-4-fluoromethyl-cyclohexane, 1-amino-4-fluoroethyl-cyclohexane, aniline, p-fluoroaniline, p-fluoromethylaniline, p-fluorobenzylamine, p-fluoromethylbenzylamine, 4-aminopiperidine, 4-amino-1-fluoroethylpiperidine, or 4-amino-1-fluoropropylpiperidine.
摘要翻译：组成和使用这种组合物的方法，其具有下式（I）或其盐，酯或水合物，其中R1是Asp-Glu磷酸酯，叔丁氧基羰基，甲氧基苯乙酰基，溴代甲氧基苯基乙基，氟甲氧基苯乙酰基，（甲基甲氧基苯基）乙酰基或碘代甲氧基苯乙酰基 ; R2是具有或不具有保护基的缬氨酸），天冬氨酸（具有或不具有保护基），1-丁基，氢，苯胺，芳族分子，叔丁氧基羰基或芴基 - 甲氧基 - 羰基; 并且R3是对硝基苯胺，7-氨基-4-甲基香豆素，氟乙胺，1-氨基-4-氟甲基 - 环己烷，1-氨基-4-氟乙基 - 环己烷，苯胺，对氟苯胺，对氟甲基苯胺，对氟苄胺，对氟甲基苄胺，4-氨基哌啶，4-氨基-1-氟乙基哌啶或4-氨基-1-氟丙基哌啶。

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