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1. 发明申请

US20140081299A1 Micromachined Ultrasonic Scalpel with Embedded Piezoelectric Actuator 审中-公开
标题翻译：微型超声波手术刀与嵌入式压电致动器
公开(公告)号：US20140081299A1
公开(公告)日：2014-03-20
申请号：US13622921
申请日：2012-09-19
申请人： Timothy G. Dietz , Yanik Tardy , Juergen Burger , Philippe Margairaz , Toralf Bork
发明人： Timothy G. Dietz , Yanik Tardy , Juergen Burger , Philippe Margairaz , Toralf Bork
IPC分类号： A61B17/32 , H01L21/62
CPC分类号： H01L21/62 , A61B17/320068 , A61B17/3211 , A61B2017/00526
摘要： An ultrasonic core including a longitudinally elongated, generally planar waveguide defining an aperture extending from a first side of the waveguide toward a medial plane of the waveguide, and having a transducer element sized and shaped so as to substantially conform to the size and shape of the aperture and to be at least partially embedded within the waveguide. In other aspects, an ultrasonic core including a longitudinally elongated, generally planar silicon waveguide having at least one transducer element secured thereto and a wedge-shaped acoustic horn including an inclined side surface, characterized in that the inclined side surface is oriented along the {1,1,1} crystallographic plane of the silicon material. Also, methods of manufacturing the respective ultrasonic cores and ultrasonic handpieces for an ultrasonic surgical instruments incorporating such cores.
摘要翻译：一种超声波芯，包括纵向细长的大致平面的波导，其限定了从波导的第一侧朝向波导的中间平面延伸的孔，并且具有尺寸和形状的换能器元件，以便基本上符合波导的尺寸和形状并且至少部分地嵌入在波导内。在其它方面，一种超声波芯，其包括纵向细长的大致平面的硅波导，其具有固定到其上的至少一个换能器元件和包括倾斜侧表面的楔形声喇叭，其特征在于，所述倾斜侧表面沿着{1 ，1,1}晶体平面的硅材料。此外，制造用于包括这种芯的超声外科器械的各个超声波芯和超声手机的方法。

2. 发明申请

US20120165794A1 Pill Catchers 审中-公开
公开(公告)号：US20120165794A1
公开(公告)日：2012-06-28
申请号：US12976761
申请日：2010-12-22
申请人： Mark S. Ortiz , Christopher J. Hess , Jason L. Harris , James W. Voegele , Mark S. Zeiner , Mark D. Overmyer , Joseph B. Kraimer , Jeff Shimizu , Rocco Crivelli , Yanik Tardy , Thierry Utard , Juergen Burger , Toralf Bork , Martin Pfleiderer , Olivier Chossat
发明人： Mark S. Ortiz , Christopher J. Hess , Jason L. Harris , James W. Voegele , Mark S. Zeiner , Mark D. Overmyer , Joseph B. Kraimer , Jeff Shimizu , Rocco Crivelli , Yanik Tardy , Thierry Utard , Juergen Burger , Toralf Bork , Martin Pfleiderer , Olivier Chossat
IPC分类号： A61M31/00
CPC分类号： A61B1/041 , A61B1/00147 , A61F5/0013 , A61M31/002
摘要： Devices and related methods are provided for the controlled delivery of a therapeutic to a targeted location within a body. More particularly, methods and devices are provided for controlling the rate of passage of an orally administered pill through a body, as well as for controlling the delivery of a therapeutic within the pill at a specific location within the body. Various types of devices, generally referred to herein as “catchers,” are provided that can actively catch a pill as it passes through a body. The catcher can hold the pill at a specific location within the body until a predetermined event occurs, such as partial or complete administration of a therapeutic within the pill. The catcher can then release the pill upon command and/or upon the occurrence of the predetermined event to allow the pill to pass out of the body. In other embodiments, various types of pills are provided that can actively engage a catcher and remain engaged with the catcher until a predetermined event occurs.

3. 发明申请

US20150045850A1 DEVICES AND METHODS FOR THE TREATMENT OF METABOLIC DISORDERS 有权
标题翻译：用于治疗代谢性疾病的装置和方法
公开(公告)号：US20150045850A1
公开(公告)日：2015-02-12
申请号：US13825459
申请日：2012-03-30
申请人： Toralf Bork , Rocco Crivelli , Mathilde Miguras , Martin Pfleiderer , Yanik Tardy , Jason L. Harris , Mark S. Ortiz , Alessandro Pastorelli , Michele D' Arcangelo
发明人： Toralf Bork , Rocco Crivelli , Mathilde Miguras , Martin Pfleiderer , Yanik Tardy , Jason L. Harris , Mark S. Ortiz , Alessandro Pastorelli , Michele D' Arcangelo
IPC分类号： A61N1/36 , A61F5/00
CPC分类号： A61N1/36007 , A61F5/0026 , A61F2005/0016 , A61F2005/002 , A61N1/0509 , A61N1/0517
摘要： An implantable system for stimulating the release of satiety hormone in a subject comprises a stimulus device (11) which is implantable in the subject and adapted to apply an electrical stimulus to a tissue of a gastrointestinal system of said subject, and a detection device which is implantable in the subject and adapted to continuously monitoring at least one of a mechanical characteristic and an electrical characteristic of the subject to detect an ingestion of food by said subject, wherein the detection device cooperates with the stimulus device (11) such that the stimulus device (11) applies said electrical stimulus in response to a detected ingestion of food.
摘要翻译：用于刺激受试者中的饱腹感激素的释放的可植入系统包括刺激装置（11），其可植入对象中并适于对所述受试者的胃肠系统的组织施加电刺激，以及检测装置可植入在受试者中并且适于连续地监测受试者的机械特性和电特性中的至少一个以检测所述受试者摄入的食物，其中检测装置与刺激装置（11）配合使得刺激装置（11）响应于检测到的食物摄入而应用所述电刺激。

4. 发明授权

US09427580B2 Devices and methods for the treatment of metabolic disorders 有权
标题翻译：用于治疗代谢紊乱的装置和方法
公开(公告)号：US09427580B2
公开(公告)日：2016-08-30
申请号：US13825459
申请日：2012-03-30
申请人： Toralf Bork , Rocco Crivelli , Mathilde Miguras , Martin Pfleiderer , Yanik Tardy , Jason L. Harris , Mark S. Ortiz , Alessandro Pastorelli , Michele D'Arcangelo
发明人： Toralf Bork , Rocco Crivelli , Mathilde Miguras , Martin Pfleiderer , Yanik Tardy , Jason L. Harris , Mark S. Ortiz , Alessandro Pastorelli , Michele D'Arcangelo
IPC分类号： A61N1/36 , A61N1/05 , A61F5/00
CPC分类号： A61N1/36007 , A61F5/0026 , A61F2005/0016 , A61F2005/002 , A61N1/0509 , A61N1/0517
摘要： An implantable system for stimulating the release of satiety hormone in a subject comprises a stimulus device which is implantable in the subject and adapted to apply an electrical stimulus to a tissue of a gastrointestinal system of said subject, and a detection device which is implantable in the subject and adapted to continuously monitoring at least one of a mechanical characteristic and an electrical characteristic of the subject to detect an ingestion of food by said subject, wherein the detection device cooperates with the stimulus device such that the stimulus device applies said electrical stimulus in response to a detected ingestion of food.
摘要翻译：用于刺激受试者中的饱腹感激素的释放的可植入系统包括刺激装置，该刺激装置可植入受试者并适于对所述受试者的胃肠系统的组织施加电刺激，以及可植入在所述受试者中的检测装置受试者并且适于连续监测受试者的机械特征和电特性中的至少一个以检测所述受试者摄取食物，其中所述检测装置与刺激装置配合使得刺激装置应答所述电刺激检测到摄入食物。

5. 发明授权

US09345813B2 Three dimensional packaging for medical implants 有权
标题翻译：医疗植入物三维包装
公开(公告)号：US09345813B2
公开(公告)日：2016-05-24
申请号：US13491081
申请日：2012-06-07
申请人： Andreas Hogg , Yanik Tardy , Thierry Aellen , Herbert Keppner , Juergen Burger
发明人： Andreas Hogg , Yanik Tardy , Thierry Aellen , Herbert Keppner , Juergen Burger
IPC分类号： B05D3/10 , B32B3/08 , B32B27/06 , B32B27/20 , A61L31/10 , A61N1/375
CPC分类号： A61L31/10 , A61L2420/02 , A61N1/375 , Y10T428/239
摘要： Implantable medical devices, and methods of coating same, including a plurality of components disposed on a substrate, and a low surface energy layer deposited as a liquid over at least a first portion of the components and the substrate, the low surface energy layer becoming solidified after deposition and conforming to at least the first portion of the components. The devices further include a biocompatible hermetic coating conforming to and sealingly covering at least a portion of the low surface energy layer.
摘要翻译：植入式医疗装置及其涂敷方法，包括设置在基板上的多个部件，以及在部件和基板的至少第一部分上作为液体沉积的低表面能层，低表面能层变得凝固在沉积之后并且至少符合组件的第一部分。这些装置还包括符合并密封地覆盖低表面能层的至少一部分的生物相容性密封涂层。

6. 发明授权

US07285296B2 Process for enriching extracts of natural theanine 失效
标题翻译：丰富天然茶氨酸提取物的方法
公开(公告)号：US07285296B2
公开(公告)日：2007-10-23
申请号：US10686910
申请日：2003-10-16
申请人： Alec Ginggen , Yanik Tardy
发明人： Alec Ginggen , Yanik Tardy
IPC分类号： A61M5/00 , A61M25/00 , A61B17/08
CPC分类号： A61M27/006
摘要： An adjustable resistance valve for a cerebrospinal fluid shunt system includes an actuator for allowing the selection of the resistance to flow of the valve, a device for selecting at least one passage traversing across the valve, and a resistance system. The resistance system includes a set of passages each defining a different resistance to flow. The passages are disposed in a circle facing the selecting device such as to guide the flow of the cerebrospinal fluid traversing the passage of the selecting device through the selected passage of the resistance system. The actuator enables one to change the relative position of the selecting device with respect to the resistance system by a rotational movement to select the desired resistance of the valve.
摘要翻译：用于脑脊液分流系统的可调节阻力阀包括用于允许选择阀的流动阻力的致动器，用于选择穿过阀的至少一个通道的装置和阻力系统。电阻系统包括一组通道，每个通道限定不同的阻力。通道设置在面向选择装置的圆圈中，以引导通过选择装置的通道的脑脊液的流动通过电阻系统的选定通道。致动器使得能够通过旋转运动来改变选择装置相对于电阻系统的相对位置，以选择阀的期望电阻。

7. 发明申请

US20120262273A1 Universal External Control Device for Use by Multiple Conditional Access Users With Varying Access to Functionality of an Implantable Medical Device 审中-公开
标题翻译：通用外部控制装置，用于多种条件访问用户，不断访问可植入医疗设备的功能
公开(公告)号：US20120262273A1
公开(公告)日：2012-10-18
申请号：US13532359
申请日：2012-06-25
申请人： Alec Ginggen , Yanik Tardy
发明人： Alec Ginggen , Yanik Tardy
IPC分类号： G05B19/00
CPC分类号： A61M5/14276 , A61M5/172 , A61M2205/3523
摘要： A universal external control device for use by multiple conditional access users with varying access to functionality of an implantable medical device in wireless communication therewith. Circuitry associated with the external control device is used to uniquely identify each of the conditional access users via an access device such as a key or card. Access to functionality of the implantable medical device is restricted by the universal external control device based on the conditional access user identified by the access device.
摘要翻译：一种通用外部控制装置，用于多个条件访问用户，其具有对与其无线通信的可植入医疗设备的功能的不同访问。与外部控制装置相关联的电路用于通过诸如钥匙或卡之类的访问装置来唯一地识别每个条件访问用户。基于由接入设备识别的条件访问用户，通过外部控制设备限制对可植入医疗设备的功能的访问。

8. 发明授权

US08229562B2 Universal external control device for use by multiple conditional access users with varying access to functionality of an implantable medical device 有权
标题翻译：通用外部控制装置，可供多个条件访问用户使用，具有对植入式医疗设备功能的不同访问
公开(公告)号：US08229562B2
公开(公告)日：2012-07-24
申请号：US11586479
申请日：2006-10-25
申请人： Alec Ginggen , Yanik Tardy
发明人： Alec Ginggen , Yanik Tardy
IPC分类号： A61N1/08
CPC分类号： A61M5/14276 , A61M5/172 , A61M2205/3523
摘要： A universal external control device for use by multiple conditional access users with varying access to functionality of an implantable medical device in wireless communication therewith. Circuitry associated with the external control device is used to uniquely identify each of the conditional access users via an access device such as a key or card. Access to functionality of the implantable medical device is restricted by the universal external control device based on the conditional access user identified by the access device.
摘要翻译：一种通用外部控制装置，用于多个条件访问用户，其具有对与其无线通信的可植入医疗设备的功能的不同访问。与外部控制装置相关联的电路用于通过诸如钥匙或卡之类的访问装置来唯一地识别每个条件访问用户。基于由接入设备识别的条件访问用户，通过外部控制设备限制对可植入医疗设备的功能的访问。

9. 发明授权

US06600945B2 Implantable nuclear magnetic resonance spectrometer 失效
标题翻译：可植入核磁共振光谱仪
公开(公告)号：US06600945B2
公开(公告)日：2003-07-29
申请号：US09797818
申请日：2001-03-02
申请人： Alec Ginggen , Yanik Tardy
发明人： Alec Ginggen , Yanik Tardy
IPC分类号： A61B505
CPC分类号： G01R33/302 , A61B5/055 , A61B5/4839 , G01R33/307
摘要： An implantable nuclear magnetic resonance spectrometer for measuring the chemical composition of a fluid or for measuring the flow rate of the fluid. The spectrometer includes a housing and a catheter traversing across the housing so that a fluid external to the housing may flow through the catheter within the housing. A permanent magnet is disposed within the housing and generates an intense homogenous magnetic field in the vicinity of the catheter. An electronic circuit is disposed within the housing for detecting and formatting a nuclear magnetic resonance excitation signal. An excitation coil is connected to the electronic circuit and is disposed about the catheter to expose the fluid within the catheter to the excitation signal and to collect the nuclear magnetic resonance excitation signal.
摘要翻译：一种用于测量流体的化学成分或用于测量流体流速的可植入核磁共振光谱仪。光谱仪包括外壳和导管穿过壳体，使得壳体外部的流体可以流过壳体内的导管。永磁体设置在壳体内，并在导管附近产生强烈均匀的磁场。电子电路设置在壳体内用于检测和格式化核磁共振激励信号。励磁线圈连接到电子电路并且围绕导管设置以将导管内的流体暴露于激励信号并收集核磁共振激励信号。

10. 发明申请

US20090204019A1 Combined Pressure and Flow Sensor Integrated in a Shunt System 审中-公开
标题翻译：集成在分流系统中的组合压力和流量传感器
公开(公告)号：US20090204019A1
公开(公告)日：2009-08-13
申请号：US12030604
申请日：2008-02-13
申请人： Alec Ginggen , Yanik Tardy
发明人： Alec Ginggen , Yanik Tardy
IPC分类号： A61B5/05 , A61M1/00
CPC分类号： A61M27/006 , A61B5/031 , A61M2205/3331
摘要： A shunt system for implantation into a patient for diverting excess fluid from the lateral ventricles of the patient's brain to a diversion site. The present shunt includes a pressure transducer for measuring ICP, a rate of flow transducer for measuring the flow rate of the CSF flowing within the shunt, and telemetry circuitry. A remote reader with an antenna is provided to selectively interrogate and provide inductive power to the implanted shunt. Upon interrogation, the pressure and rate of flow measurements are calibrated, multiplexed and transmitted on a carrier signal back to the remote reader/antenna. The reader/antenna extracts the pressure and flow rate data from the carrier wave and further separates the data by demultiplexing the signal. The reader further includes a barometer for providing local barometric pressure and uses this information together with the data from the implanted transducers to calculate and display real-time adjusted ICP, CSF flow-rate within the shunt and brain compliance.
摘要翻译：一种用于植入患者的分流系统，用于将多余的流体从患者的大脑的侧脑室转移到转移部位。本分流器包括用于测量ICP的压力传感器，用于测量在分流器内流动的CSF的流量的流量传感器的速率和遥测电路。提供具有天线的远程读取器以选择性地询问并向所述植入的分流器提供感应电力。在询问时，流量测量的压力和速率被校准，多路复用并在载波信号上发送回到远程读取器/天线。读取器/天线从载波提取压力和流量数据，并且通过解复用信号来进一步分离数据。阅读器还包括用于提供局部大气压力的气压计，并将该信息与植入的换能器的数据一起计算并显示分流和大脑顺应性内的实时调节的ICP，CSF流率。

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