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    • 2. 发明授权
    • Cis-substituted fluoromethylpyrrolidine derivative
    • 顺式取代的氟甲基吡咯烷衍生物
    • US06656952B2
    • 2003-12-02
    • US09446696
    • 1999-12-23
    • Makoto TakemuraHisashi TakahashiHitoshi OhkiKenichi KimuraRie MiyauchiToshiyuki Takeda
    • Makoto TakemuraHisashi TakahashiHitoshi OhkiKenichi KimuraRie MiyauchiToshiyuki Takeda
    • A61K3147
    • C07D401/04
    • An antibacterial drug having potent antibacterial activities upon various bacteria including resistant strains and high safety is disclosed, which comprises as an active ingredient, quinolone derivatives represented by the following formula (I), its salts or hydrates thereof: wherein R1 represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms, R2 represents a halogenomethoxyl group or an alkoxyl group, R3 represents an alkyl group, an alkenyl group, a halogenoalkyl group, a cyclic alkyl group, a heteroaryl group, an alkoxyl group or an alkylamino group, and R4 represents a hydrogen atom, a phenyl group, an acetoxymethyl group, a pivaloyloxymethyl group, an ethoxycarbonyl group, a choline group, a dimethylaminoethyl group, a 5-indanyl group, a phthalidinyl group, a 5-alkyl-2-oxo-1,3-dioxol-4-ylmethyl group, 3-acetoxy-2-oxobutyl group, an alkyl group, an alkoxylmethyl group or a phenylalkyl group. These substituents may further have additional substituents.
    • 本发明公开了一种对各种细菌(包括耐药菌株)和高度安全性具有有效抗菌活性的抗菌药物,其包含作为活性成分的由下式(I)表示的喹诺酮衍生物,其盐或水合物:其中R 1表示 氢原子或碳原子数1〜6的烷基,R 2表示卤代甲氧基或烷氧基,R 3表示烷基,链烯基,卤代烷基,环状烷基,杂芳基 基团,烷氧基或烷基氨基,R 4表示氢原子,苯基,乙酰氧基甲基,新戊酰氧基甲基,乙氧基羰基,胆碱基,二甲基氨基乙基,5-二氢化茚基, 5-烷基-2-氧代-1,3-二氧杂环戊烯-4-基甲基,3-乙酰氧基-2-氧代丁基,烷基,烷氧基甲基或苯基烷基。 这些取代基还可以具有另外的取代基。
    • 7. 发明授权
    • Electronic circuit capable of stably keeping a frequency during presence
of a burst
    • 能够在存在突发时稳定地保持频率的电子电路
    • US4633510A
    • 1986-12-30
    • US687343
    • 1984-12-28
    • Fumiaki SuzukiToshiyuki TakedaTakeo InoueShigeo Nakajima
    • Fumiaki SuzukiToshiyuki TakedaTakeo InoueShigeo Nakajima
    • H03L7/14H04B1/40H04B7/15H04B7/155H04B1/00
    • H04B1/40H03L7/14
    • In a radio communication system, a transmitting section of a substation comprises a controlling circuit (21) for controlling a carrier frequency of a local oscillator (24) in response to a frequency deviation signal. A burst generating circuit (26) generates a burst in response to the input signal, a burst control signal, and a local oscillation signal of the carrier frequency. The transmitting section further comprises a holding circuit (34) responsive to a frequency control signal and the burst control signal. During presence of the burst control signal, the holding circuit holds the frequency control signal received before a beginning of the burst control signal to keep the carrier frequency of the local oscillation signal invariable until an end of the burst control signal. Otherwise, the frequency control signal passes through the holding circuit as it stands. Consequently, the carrier frequency of the local oscillation signal is controlled only during absence of the input signal and is kept invariable during presence of the input signal.
    • 在无线电通信系统中,变电站的发送部分包括用于响应于频率偏差信号来控制本地振荡器(24)的载波频率的控制电路(21)。 突发发生电路(26)响应于输入信号,脉冲串控制信号和载波频率的本地振荡信号产生脉冲串。 发送部分还包括响应于频率控制信号和突发控制信号的保持电路(34)。 在脉冲串控制信号的存在期间,保持电路保持在突发控制信号开始之前接收到的频率控制信号,以保持本地振荡信号的载波频率不变,直到脉冲串控制信号的结束。 否则,频率控制信号就一直通过保持电路。 因此,本地振荡信号的载波频率仅在没有输入信号的情况下被控制,并且在存在输入信号的过程中保持不变。
    • 8. 发明授权
    • Disc brake for motor vehicles
    • 机动车盘式制动器
    • US06851524B2
    • 2005-02-08
    • US10606802
    • 2003-06-27
    • Toshiyuki TakedaBunzo SekiYuji Hayashi
    • Toshiyuki TakedaBunzo SekiYuji Hayashi
    • F16D55/224F16D55/227F16D65/02F16D65/14F16D65/38
    • F16D55/227F16D55/22655F16D2055/0008F16D2121/02F16D2121/14F16D2123/00F16D2125/40
    • The disc brake for a motor vehicle contains a caliper bracket to be secured to a vehicle body on the outer side of a disc rotor with respect to the vehicle body, a caliper body supported by the caliper bracket to be slidable in the axial direction of the disc rotor and a pair of friction pads disposed to oppose each other through the disc rotor. The caliper bracket contains a bracket main body and a connecting arm which are disposed respectively on the outer side and on the inner side of the disc rotor with respect to the vehicle body, as well as, a pair of caliper supporting arms, which connect the bracket main body with the connecting arm at their disc turning-in side end portions and at their disc turning-out side end portions, respectively. The bracket main body and the connecting arm have torque receiving portions at least on the disc turning-out side respectively to receive braking torques from the respective friction pads; the bracket main body has a disc turning-out side fixing portion, where the caliper bracket is secured to the vehicle body, located outer than the disc turning-out side torque receiving portion toward the disc turning-out side and substantially on the peripheral edge of the disc rotor.
    • 用于机动车辆的盘式制动器包括卡钳支架,其被固定到相对于车身的盘形转子的外侧上的车身,由卡钳托架支撑的卡钳体可沿着该车辆的轴向方向滑动 盘形转子和通过盘形转子彼此相对设置的一对摩擦垫。 卡钳支架包括分别设置在盘转子相对于车体的外侧和内侧的支架主体和连接臂,以及一对卡钳支撑臂,其连接 支架主体,其连接臂分别在盘的转动侧端部和盘的转出侧端部。 支架主体和连接臂分别至少在盘转出侧上具有转矩接收部分,以从各个摩擦垫接收制动力矩; 支架主体具有盘转出侧固定部,卡钳支架固定在车体上,位于盘转出侧转矩接收部的外侧,朝向盘转出侧且基本上位于周缘 的圆盘转子。
    • 10. 发明授权
    • Cycloalkyl-substituted aminomethylpyrrolidine derivatives
    • 环烷基取代的氨基甲基吡咯烷衍生物
    • US06573260B1
    • 2003-06-03
    • US09856631
    • 2001-05-24
    • Makoto TakemuraHisashi TakahashiRie MiyauchiToshiyuki TakedaIsao Hayakawa
    • Makoto TakemuraHisashi TakahashiRie MiyauchiToshiyuki TakedaIsao Hayakawa
    • A61K314709
    • C07D401/04
    • This invention provides a quinolone derivative which exerts strong antibacterial action upon various bacteria and has high safety, and it relates to a compound having a structure of formula (I), its salts and hydrates thereof: {R1 and R2: hydrogen, alkyl; n: 1 to 4; Q: following structure (Ia): [R3: alkyl, alkenyl, halogenoalkyl, cyclic alkyl, aryl, heteroaryl, alkoxyl, alkylamino; R4: hydrogen, alkylthio; R5: hydrogen, amino, hydroxyl, thiol, halogenomethyl, alkyl, alkenyl, alkynyl, alkoxyl; X1: halogen, hydrogen, A1: nitrogen, structure of formula (II): (X2: hydrogen, amino, halogen, cyano, halogenomethyl, halogenomethyl, alkyl, alkenyl, alkynyl, alkoxyl; R4 and R3 or X2 and R3 may together form a cyclic structure; Y: hydrogen, various ester forming groups]}.
    • 本发明提供了一种喹诺酮衍生物,其对各种细菌具有强烈的抗菌作用并具有高度的安全性,它涉及具有式(I)结构的化合物及其盐和水合物:{R1和R2:氢,烷基; n:1到4; Q:以下结构(Ia):[R3:烷基,烯基,卤代烷基,环烷基,芳基,杂芳基,烷氧基,烷基氨基; R4:氢,烷硫基; R5:氢,氨基,羟基,硫醇,卤代甲基,烷基,烯基,炔基,烷氧基; X1:卤素,氢,A1:氮,式(II)的结构:(X2:氢,氨基,卤素,氰基,卤代甲基,卤代甲基,烷基,烯基,炔基,烷氧基; R4和R3或X2和R3可以一起形成 环状结构; Y:氢,各种酯形成基团]}。