专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 再颁专利

USRE34960E Carbapenem compounds, and compositions containing them 失效
标题翻译：碳青霉烯化合物和含有它们的组合物
公开(公告)号：USRE34960E
公开(公告)日：1995-05-30
申请号：US52849
申请日：1987-05-20
申请人： Tetsuo Miyadera , Yukio Sugimura , Toshihiko Hashimoto , Teruo Tanaka , Kimio Iino , Tomoyuki Shibata , Shinichi Sugawara
发明人： Tetsuo Miyadera , Yukio Sugimura , Toshihiko Hashimoto , Teruo Tanaka , Kimio Iino , Tomoyuki Shibata , Shinichi Sugawara
IPC分类号： C07D487/04 , A61K31/40 , C07D20060101 , C07D207/12 , C07D477/00 , C07D477/20 , C07D487/00 , C07D487/06
CPC分类号： C07D477/20 , C07D207/12
摘要： Compounds of formula (I): ##STR1## .[.[.]. wherein: R.sup.1 .[.represents a hydrogen atom, an alkyl group, an alkoxy group or various substituted alkyl groups.]. .Iadd.is hydroxyethyl; .Iaddend.R.sup.2 represents a group of formula ##STR2## in which ##STR3## .[.represents an alicyclic amine group having from 4 to 8 ring atoms, optionally having a single double bond, optionally containing an additional hetero-atom and optionally having an oxo group on the ring;.]. .Iadd.is a 3-pyrrolidinyl group; .Iaddend.X represents a hydrogen atom.[.; an alkyl group, an alkoxy group, an alkylthio group, an alkylsulphinyl group, an alkylsulphonyl group, a hydroxy group, a halogen atom or various substituted alkyl groups.].;Y represents .[.a hydrogen atom, an alkyl group, an aliphatic acyl group or an acylimidoyl.]. .Iadd.an acetylimidoyl .Iaddend.group; andR.sup.3 represents a carboxy group or a protected carboxy group.[.].].and pharmaceutically acceptable salts thereof have valuable antibacterial activity, especially in vivo.

2. 发明授权

US4377591A 7-Oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives, their use and preparation 失效
标题翻译： 7-氧代-1-氮杂双环[3.2.0]庚-2-烯-2-羧酸衍生物，其用途和制备方法
公开(公告)号：US4377591A
公开(公告)日：1983-03-22
申请号：US239139
申请日：1981-02-27
申请人： Tetsuo Hiraoka , Takeo Kobayashi , Noboru Ishida , Shinichi Sugawara
发明人： Tetsuo Hiraoka , Takeo Kobayashi , Noboru Ishida , Shinichi Sugawara
IPC分类号： C07D477/00 , A61K31/397 , A61K31/40 , A61P31/04 , C07D205/08 , C07D477/14 , C07F7/10 , C07F7/18 , C07F9/568 , C07D487/04
CPC分类号： C07D477/14 , C07D205/08 , C07F7/10 , C07F7/186 , C07F9/5683 , Y02P20/55
摘要： 7-Oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives of formula (I): ##STR1## (in which:) R.sup.1 represents a hydrogen atom or an optionally substituted alkyl group;X represents an oxy group, a thio group, a sulphinyl group or a sulphonyl group;A represents a bivalent for trivalent saturated aliphatic hydrocarbon group;p is 1 (when A is bivalent) or 2 (when A is trivalent);R.sup.2 represents an azido, nitro or cyano group or one of the groups of formula ##STR2## m and n are the same or different and each is 0 or 1; R represents an amidino group or a group of formula R.sup.4, --N(R.sup.4).sub.2 or --YR.sup.4,B represents a group of formula ##STR3## D represents a group of formula ##STR4## (provided that, where m and n are both 1, the groups represented by B and D must be different);R.sup.4 represents a hydrogen atom or an alkyl group and, where there are 2 or more groups represented by R.sup.4, they may be the same or different, andY represents an oxygen atom or a sulphur atom; andR.sup.3 represents a carboxy group or a protected carboxy group)and pharmaceutically acceptable salts thereof are valuable antibiotics and may be prepared by a process which includes heating a corresponding phosphorus-ylide compound.
摘要翻译：（I）的7-氧代-1-氮杂双环[3.2.0]庚-2-烯-2-羧酸衍生物：其中：R 1表示氢原子或任选取代的烷基组; X表示氧基，硫基，亚磺酰基或磺酰基; A代表三价饱和脂族烃基的二价; p为1（当A为二价时）或2（当A为三价时）; R 2表示叠氮基，硝基或氰基，或者式中的一个基团m和n相同或不同，各自为0或1; R表示脒基或式R4，-N（R4）2或-YR4的基团，B表示式的基团D表示式的基团（条件是，其中m和n均为 1，由B和D表示的基团必须不同）; R 4表示氢原子或烷基，其中，R 2表示2个以上基团时，可以相同或不同，Y表示氧原子或硫原子。并且R 3表示羧基或保护的羧基）及其药学上可接受的盐是有价值的抗生素，并且可以通过包括加热相应的磷内酯化合物的方法来制备。

3. 发明申请

US20070087170A1 Manufacturing method of tape and tape 审中-公开
标题翻译：胶带和胶带的制造方法
公开(公告)号：US20070087170A1
公开(公告)日：2007-04-19
申请号：US11580914
申请日：2006-10-16
申请人： Kyouhisa Uchiumi , Yutaka Kakuishi , Shinichi Sugawara , Hideaki Yamada
发明人： Kyouhisa Uchiumi , Yutaka Kakuishi , Shinichi Sugawara , Hideaki Yamada
IPC分类号： B32B23/02
CPC分类号： G11B15/66 , G11B5/84 , Y10T428/24777
摘要： A manufacturing method of a tape for manufacturing a curved tape curving in the width direction along the longitudinal direction of the tape, wherein, in a cutting process which cuts an original tape with a wide width into a plurality of tapes with a predetermined width by continuously passing the original tape between a rotary blade and a rotary bed knife having a receiving portion for receiving the rotary blade, an edge which has a shorter edge length between both edges in the width direction of the tape is to become a cut side by being pushed into the receiving portion of the rotary bed knife.
摘要翻译：一种用于制造沿带的纵向在宽度方向上弯曲的弯曲带的带的制造方法，其中，在将具有宽宽度的原始带以连续的方式切割成预定宽度的多个带的切割过程中将原始带材转动在具有用于接收旋转刀片的接收部分的旋转刀片和旋转床刀之间，沿着带的宽度方向在两个边缘之间具有较短边缘长度的边缘通过被推动成为切割侧进入旋转床刀的接收部分。

4. 发明授权

US4395418A Penem-3-carboxylic acid derivatives 失效
标题翻译：甘氨酸-3-羧酸衍生物
公开(公告)号：US4395418A
公开(公告)日：1983-07-26
申请号：US271010
申请日：1981-06-05
申请人： Eiji Ohki , Sadao Oida , Akira Yoshida , Teruo Hayashi , Shinichi Sugawara
发明人： Eiji Ohki , Sadao Oida , Akira Yoshida , Teruo Hayashi , Shinichi Sugawara
IPC分类号： C07D205/09 , C07D499/88 , C07F7/18 , C07F9/568 , A61K31/425 , C07D499/00
CPC分类号： C07F7/186 , C07D205/09 , C07D499/88 , C07F9/5683 , Y02P20/55
摘要： Penem-3-carboxylic acid derivatives of formula (I): ##STR1## (wherein: R.sup.1 represents a hydrogen atom, an alkyl group, an alkoxy group, a hydroxyalkyl group, an acyloxyalkyl group, an alkylsulphonyloxyalkyl group, an arylsulphonyloxyalkyl group or a trialkylsilyloxyalkyl group;R.sup.2 represents a hydrogen atom or an alkyl group;R.sup.3 represents a hydrogen atom, an amino-protecting group or a group of formula ##STR2## in which R.sup.5 and R.sup.6 are the same or different and each represents a hydrogen atom or an alkyl group;A represents a branched-chain alkylene group; andR.sup.4 represents a carboxy group or a protected carboxy group)and pharmaceutically acceptable salts thereof, may be prepared by heating a corresponding phosphorus-ylide compound or by reacting a corresponding azetidin-2-one with a suitable phosphorous acid triester or triamide, and have been found to have excellent antibacterial activity accompanied by a very low acute toxicity.
摘要翻译：（I）的半酯-3-羧酸衍生物：其中：R1表示氢原子，烷基，烷氧基，羟烷基，酰氧基烷基，烷基磺酰氧基烷基，芳基磺酰氧基烷基基团或三烷基甲硅烷氧基烷基; R 2表示氢原子或烷基; R 3表示氢原子，氨基保护基或式“IMAGE”基团，其中R 5和R 6相同或不同，并且各自表示氢原子或烷基; A表示支链亚烷基; R4表示羧基或保护的羧基）及其药学上可接受的盐可以通过加热相应的磷内酯化合物或通过使相应的氮杂环丁烷 -2-酮与合适的亚磷酸三酯或三酰胺，发现具有优异的抗菌活性，伴随着非常低的急性毒性。

5. 发明授权

US4147863A 7-D-(-)-mandelamido-3-(1-methyl-1H-tetrazol-5-yl)vinyl- 3-cephem-4-carboxylic acid 失效
标题翻译： 7-D - （{31-） - 扁桃酰氨基-3-（1-甲基-1H-四唑-5-基）乙烯基-3-头孢烯-4-羧酸
公开(公告)号：US4147863A
公开(公告)日：1979-04-03
申请号：US607690
申请日：1975-08-25
申请人： Tetsuo Miyadera , Mitsuo Nagano , Shinichi Sugawara
发明人： Tetsuo Miyadera , Mitsuo Nagano , Shinichi Sugawara
IPC分类号： C07D501/24 , C07D501/38 , C07D501/48 , C07F9/6524 , C07K5/06
CPC分类号： C07K5/06191 , C07F9/6524
摘要： Novel cephalosporin derivatives having a (1-alkyl-1H-tetrazol-5-yl)vinyl group at the 3-position of the cephem nucleus and showing an excellent antibacterial activity are disclosed. A process for preparing the cephalosporin derivatives is also disclosed.
摘要翻译：公开了在头孢烯核的3位具有（1-烷基-1H-四唑-5-基）乙烯基的新型头孢菌素衍生物，具有优异的抗菌活性。还公开了一种制备头孢菌素衍生物的方法。

6. 发明授权

US4007177A Cephalosporin derivatives 失效
标题翻译：头孢菌素衍生物
公开(公告)号：US4007177A
公开(公告)日：1977-02-08
申请号：US523819
申请日：1974-11-14
申请人： Hideo Nakao , Hiroaki Yanagisawa , Mitsuo Nagano , Bunji Shimizu , Masakatsu Kaneko , Shinichi Sugawara
发明人： Hideo Nakao , Hiroaki Yanagisawa , Mitsuo Nagano , Bunji Shimizu , Masakatsu Kaneko , Shinichi Sugawara
IPC分类号： C07C323/48 , C07D261/10 , C07D261/12 , C07D309/12 , C07D501/57 , C07D505/00 , C07D501/50 , C07D501/56
CPC分类号： C07D309/12 , C07D261/10 , C07D261/12 , Y02P20/55
摘要： A compound of the formula ##STR1## wherein A represents acetoxy group, carbamoyloxy group or (1-metyl-1H-tetrazol-5-yl)thio group and Y represents propargylthio group, azidomethylthio group, 2-hydroxyethylthio group, 3-isoxazolyloxy group, 3-isoxazolylthio group, methylsulfonyl group, ethylsulfonyl group, 2-cyanoethyl-sulfonyl group or sydnon-3-yl group and nontoxic pharmaceutically acceptable salts thereof are prepared by a process which comprises reacting a compound of the formula ##STR2## wherein R represents a protective group for a carboxyl group and A has the same meaning as defined above with a carboxylic acid of the formulaY - CH.sub.2 COOHwherein Y has the same meaning as defined above or a reactive derivative thereof to give a compound having the formula ##STR3## wherein A, R and Y have the same meanings as defined above and removing the protective group for the carboxyl group from said compound.The compounds are antibacterial agents.
摘要翻译：其中A表示乙酰氧基，氨基甲酰氧基或（1-甲基-1H-四唑-5-基）硫基，Y表示炔丙硫基，叠氮甲硫基，2-羟乙硫基，3-异恶唑基氧基 3-异恶唑基硫代基，甲基磺酰基，乙基磺酰基，2-氰基乙基磺酰基或者sydnon-3-基及其无毒的药学上可接受的盐通过以下方法制备，该方法包括使下式化合物羧基的保护基和A具有如上所定义的与式Y-CH 2 COOH的羧酸的含义，其中Y具有与上述相同的含义或其反应性衍生物，得到具有下式的化合物：其中A，R和Y具有与上述相同的含义，并从所述化合物中除去羧基的保护基。

7. 发明申请

US20060220277A1 Tape-form recording medium and manufacturing method thereof 审中-公开
标题翻译：带状记录介质及其制造方法
公开(公告)号：US20060220277A1
公开(公告)日：2006-10-05
申请号：US11396575
申请日：2006-04-04
申请人： Ryota Suzuki , Shinichi Sugawara
发明人： Ryota Suzuki , Shinichi Sugawara
IPC分类号： B29C71/00
CPC分类号： G11B5/84 , B29C71/0072 , B29C71/02 , B29L2017/008
摘要： A manufacturing method of a tape-form recoding medium in the present invention is configured with a raw web winding process of winding on a winding core raw web having a support body, a data recoding layer laminated on one side of the support body, and a minute convexity laminated on the other side thereof; a raw web rewinding process of rewinding on other winding cores the raw web wound on the winding core in the raw web winding core; and a heat treatment process of heating the rewound raw web and decreasing a number of a concavity not less than 30 nm in depth formed in the data recording layer in the raw web winding process to not more than 80 pieces/mm2.
摘要翻译：在本发明的带状记录介质的制造方法中，将卷绕在具有支撑体的卷绕芯部原料网上的原料卷绕过程，层叠在支撑体一侧的数据记录层，以及其另一侧层叠有微小凸起; 在其他卷绕芯上卷绕卷绕在原料卷绕芯中的卷绕芯上的原料卷的原料卷筒卷绕过程; 以及在原料卷绕过程中将数据记录层中形成的深度不小于30nm的多个凹面加热到不超过80个/ mm 2的热卷绕处理过程， / SUP>。

8. 发明申请

US20060103961A1 Digital recording and reproducing apparatus, recording medium used therefor, and error factor estimating method and error factor estimating system thereof 审中-公开
标题翻译：数字记录和再现装置，用于其的记录介质，以及误差因子估计方法和误差因子估计系统
公开(公告)号：US20060103961A1
公开(公告)日：2006-05-18
申请号：US11260262
申请日：2005-10-28
申请人： Shinichi Sugawara , Masayuki Usui
发明人： Shinichi Sugawara , Masayuki Usui
IPC分类号： G11B27/36
CPC分类号： G11B20/18 , G11B27/36 , G11B2220/90
摘要： An error factor estimating method estimates a factor of an error occurring when information recorded on a digital recording medium is reproduced by a digital recording and reproducing apparatus. The error factor estimating method includes the steps of: recording error factor estimation data on a digital recording medium; reproducing the error factor estimation data from the digital recording medium to obtain an error factor estimation signal; and estimating the factor of the error based on the factor estimation. The error factor estimating method can estimate the factor of occurrence of the error based on a factor estimation signal obtained by reproducing the error factor estimation data from the recording medium by the digital recording and reproducing device without affecting user data recorded on the recording medium at all.
摘要翻译：当由数字记录和再现装置再现记录在数字记录介质上的信息时，误差因子估计方法估计发生的误差因子。误差因子估计方法包括以下步骤：在数字记录介质上记录误差因子估计数据; 从数字记录介质再现误差因子估计数据以获得误差因子估计信号; 并基于因子估计来估计误差因子。误差因子估计方法可以基于通过由数字记录和再现装置从记录介质再现误差因子估计数据而获得的因子估计信号来估计误差的出现因子，而不影响记录在记录介质上的用户数据。

9. 发明授权

US4639441A 2-penem-3-carboxylic acid derivatives and use 失效
标题翻译： 2-青霉烯-3-羧酸衍生物和用途
公开(公告)号：US4639441A
公开(公告)日：1987-01-27
申请号：US582152
申请日：1984-02-24
申请人： Tetsuo Miyadera , Yukio Sugimura , Teruo Tanaka , Toshihiko Hashimoto , Kimio Iino , Shinichi Sugawara
发明人： Tetsuo Miyadera , Yukio Sugimura , Teruo Tanaka , Toshihiko Hashimoto , Kimio Iino , Shinichi Sugawara
IPC分类号： C07D205/09 , C07D499/26 , C07D499/86 , C07D499/88 , C07F7/18 , C07D499/00 , A61K31/425
CPC分类号： C07D205/09 , C07D499/88 , C07F7/186
摘要： Compounds of formula (I): ##STR1## in which: R.sup.1 represents a hydrogen atom, an alkyl group, an alkoxy group or various substituted alkyl groups;R.sup.2 represents a hydrogen atom, a group of formula ##STR2## (in which R.sup.5 and R.sup.6 each represents an alkyl group, an aralkyl group or an aryl group, or R.sup.5 and R.sup.6 together represent a nitrogen-containing heterocyclic group) or a group of formula ##STR3## (in which R.sup.7 represents a hydrogen atom, a substituted or unsubstituted alkyl group, a substituted or unsubstituted amino group, a cyclic amino group, a hydroxy group, an alkoxy group, an aryloxy group, an aralkyloxy group, a substituted or unsubstituted hydrazino group or a guanidino group, and A' represents a bivalent saturated aliphatic hydrocarbon group); andR.sup.3 represents a carboxy group or a protected carboxy group; and pharmaceutically acceptable salts thereof are valuable antibiotics and may be prepared from the corresponding 1-(protected carboxymethyl)-4-alkylthio-azetidin-2-one.
摘要翻译：式（I）化合物：其中：R1表示氢原子，烷基，烷氧基或各种取代的烷基; R 2表示氢原子，式（IMAGE）（其中R 5和R 6各自表示烷基，芳烷基或芳基，或R 5和R 6一起代表含氮杂环基团）的基团式中，R 7表示氢原子，取代或未取代的烷基，取代或未取代的氨基，环状氨基，羟基，烷氧基，芳氧基，芳烷氧基，取代的或未取代的肼基或胍基，A'表示二价饱和脂族烃基）。并且R 3表示羧基或保护的羧基; 和其药学上可接受的盐是有价值的抗生素，并且可以由相应的1-（保护的羧甲基）-4-烷硫基 - 氮杂环丁-2-酮制备。

10. 发明授权

US4613595A Penem derivatives, and composition containing them 失效
标题翻译： Penem衍生物和含有它们的组合物
公开(公告)号：US4613595A
公开(公告)日：1986-09-23
申请号：US494570
申请日：1983-05-13
申请人： Tetsuo Miyadera , Yukio Sugimura , Toshihiko Hashimoto , Teruo Tanaka , Kimio Iino , Tomoyuki Shibata , Shinichi Sugawara
发明人： Tetsuo Miyadera , Yukio Sugimura , Toshihiko Hashimoto , Teruo Tanaka , Kimio Iino , Tomoyuki Shibata , Shinichi Sugawara
IPC分类号： C07D205/08 , A61K31/397 , A61K31/505 , A61P31/04 , C07D205/09 , C07D207/12 , C07D477/00 , C07D477/20 , C07D499/88 , C07D499/897 , C07F7/18 , C07D499/00 , A61K31/425
CPC分类号： C07D477/20 , C07D207/12 , Y02P20/55
摘要： Compounds of formula (I): ##STR1## (wherein R.sup.1 represents a C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.3 alpha-hydroxyalkyl group;R.sup.2 represents a hydrogen atom, a substituted or unsubstituted alkyl group or a cycloalkyl group;R.sup.3 represents a hydrogen atom or an alkyl group; and n is 1 or 2) and their salts and esters have valuable antibiotic activity and can be used for the treatment of diseases caused by a wide range of pathogenic microorganisms.
摘要翻译：式（I）化合物：其中R 1表示C 1 -C 4烷基或C 1 -C 3α-羟基烷基; R 2表示氢原子，取代或未取代的烷基或环烷基; R 3表示氢原子或烷基; n为1或2），其盐和酯具有有价值的抗生素活性，可用于治疗由广泛的致病微生物引起的疾病。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式