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1. 发明授权

US5642953A Multiplex writing implement 失效
标题翻译：复写书写工具
公开(公告)号：US5642953A
公开(公告)日：1997-07-01
申请号：US529585
申请日：1995-09-18
申请人： Seiichi Kobayashi , Naoki Sekiguchi
发明人： Seiichi Kobayashi , Naoki Sekiguchi
IPC分类号： B43K24/14 , B43K29/02 , B43K27/00
CPC分类号： B43K29/02 , B43K24/14
摘要： A multiplex writing implement includes a mechanical pencil refill and ball-point pen refill which can be selectively used as desired, and is equipped with a delivering mechanism for delivering a stick-shaped article such as an eraser etc. The multiplex writing implement further includes: a front barrel for accommodating at least tip portions of these refills; a middle barrel for accommodating the remaining parts of these refills; a rear barrel which is able to rotate clockwise or counterclockwise relative to the middle barrel; and a cylindrical cam which moves integrally with the rear barrel and, in accordance with the rotational direction of the rear barrel, allows selective use of one of the refills by projecting any one of the refills from the front end of the front barrel and retracting the other refill. In this configuration, the front and middle barrels are integrally joined in such a state that each barrel is prevented from rotating and falling off relative to the other barrel.
摘要翻译：一种多功能书写工具，包括可根据需要选择性地使用的机械式笔芯笔芯和圆珠笔笔芯，并配备有用于传送诸如橡皮擦等的棒状物品的输送机构。多重书写工具还包括：一个前筒，用于容纳至少这些笔芯的尖端部分; 用于容纳这些补充物的剩余部分的中间桶; 能够相对于中筒顺时针或逆时针旋转的后筒; 以及与后筒一体地移动的圆柱形凸轮，并且根据后筒的旋转方向，允许通过从前筒的前端突出任何一个重新填充物来选择性地使用重新填充物中的一个，并且缩回其他充值在这种构造中，前筒和中筒一体地接合在一起，使得每个筒相对于另一个筒被防止旋转和脱落。

2. 发明授权

US09086531B2 Plastic polarized lens, method for producing the same, and polarized film 有权
标题翻译：塑料偏光镜片，其制造方法和偏光膜
公开(公告)号：US09086531B2
公开(公告)日：2015-07-21
申请号：US13813312
申请日：2011-08-10
申请人： Akinori Ryu , Seiichi Kobayashi , Hiroyuki Kamio , Yoshiharu Kobayashi , Mitsuru Sakai , Yoshimitsu Aiiso
发明人： Akinori Ryu , Seiichi Kobayashi , Hiroyuki Kamio , Yoshiharu Kobayashi , Mitsuru Sakai , Yoshimitsu Aiiso
IPC分类号： G02B1/08 , B29D11/00 , C09B47/00 , G02B1/04 , G02B5/30 , B29C39/10 , B29C39/12 , B29C33/10 , B29K75/00
CPC分类号： G02B1/08 , B29C33/10 , B29C39/10 , B29C39/12 , B29K2075/00 , B29K2995/0034 , C09B47/00 , G02B1/041 , G02B5/3033 , G02B2207/113 , C08L81/00 , C08L75/04
摘要： The plastic polarized lens (10) of the present invention contains a polarized film (12) and layers (resin layers) (14a and 14b) comprising a thiourethane-based resin stacked over both surfaces of the polarized film (12), and the polarized film contains an organic coloring compound represented by the following general formula (1).
摘要翻译：本发明的塑料偏光透镜（10）包含偏振膜（12）和层叠在偏振膜（12）的两个表面上的硫代氨基甲酸酯类树脂的层（树脂层）（14a和14b），并且偏振膜包含由以下通式（1）表示的有机着色化合物。

3. 发明授权

US08426551B2 Metal thietane compound, polymerizable composition containing the compound, resin and use of the resin 有权
标题翻译：金属硫杂环丁烷化合物，含有该化合物的可聚合组合物，树脂和该树脂的用途
公开(公告)号：US08426551B2
公开(公告)日：2013-04-23
申请号：US13616777
申请日：2012-09-14
申请人： Masakazu Murakami , Tomoyuki Ando , Hironori Kuboi , Hidetoshi Hayashi , Osamu Kohgo , Seiichi Kobayashi
发明人： Masakazu Murakami , Tomoyuki Ando , Hironori Kuboi , Hidetoshi Hayashi , Osamu Kohgo , Seiichi Kobayashi
IPC分类号： C08G75/00
CPC分类号： C08G75/06 , C08L81/02 , G02B1/041
摘要： Polymerizable compositions containing at least one metal thietane compound represented by general formulas (110), (201) or (120), respectively, wherein said formulas are as follows: and wherein the identified moieties and n, p, q and r are defined.
摘要翻译：分别含有至少一种由通式（110），（201）或（120）表示的金属硫杂环丁烷化合物的可聚合组合物，其中所述式如下：其中所定义的部分和n，p，q和r被定义。

4. 发明申请

US20130018169A1 Metal Thietane Compound, Polymerizable Composition Containing the Compound, Resin and Use of the Resin 有权
标题翻译：金属硫杂环丁烷化合物，含有化合物的可聚合组合物，树脂和树脂的用途
公开(公告)号：US20130018169A1
公开(公告)日：2013-01-17
申请号：US13616777
申请日：2012-09-14
申请人： Masakazu Murakami , Tomoyuki Ando , Hironori Kuboi , Hidetoshi Hayashi , Osamu Kohgo , Seiichi Kobayashi
发明人： Masakazu Murakami , Tomoyuki Ando , Hironori Kuboi , Hidetoshi Hayashi , Osamu Kohgo , Seiichi Kobayashi
IPC分类号： C07F9/90 , C08G79/00 , C09K3/00 , C07F9/94
CPC分类号： C08G75/06 , C08L81/02 , G02B1/041
摘要： Polymerizable compositions containing at least one metal thietane compound represented by general formulas (110), (201) or (120), respectively, wherein said formulas are as follows: and wherein the identified moieties and n, p, q and r are defined.
摘要翻译：分别含有至少一种由通式（110），（201）或（120）表示的金属硫杂环丁烷化合物的可聚合组合物，其中所述式如下：其中所定义的部分和n，p，q和r被定义。

5. 发明申请

US20110245531A1 PROCESS FOR PRODUCING PENTAERYTHRITOL MERCAPTOCARBOXYLIC ACID ESTER, PENTAERYTHRITOL MERCAPTOCARBOXYLIC ACID ESTER OBTAINED BY THE SAME, AND USE THEREOF 审中-公开
标题翻译：生产戊二酸三辛酯酸酯的方法，由其获得的戊二酸甘油酸酯酯及其用途
公开(公告)号：US20110245531A1
公开(公告)日：2011-10-06
申请号：US13160988
申请日：2011-06-15
申请人： Shigetoshi KUMA , Koichi Tokunaga , Norihiko Fukatsu , Seiichi Kobayashi
发明人： Shigetoshi KUMA , Koichi Tokunaga , Norihiko Fukatsu , Seiichi Kobayashi
IPC分类号： C07C323/52
CPC分类号： C07C319/12 , C08G18/3876 , C08G18/7642 , G02B1/04 , C08L75/04 , C07C323/52
摘要： Pentaerythritol which contains none of the alkali metals and the alkaline earth metals or which contains at least one of these in a total amount of 1.0 weight % or smaller is reacted with a mercaptocarboxylic acid to produce a pentaerythritol mercaptocarboxylic acid ester.
摘要翻译：不含有碱金属和碱土金属或其中至少一种的总量为1.0重量％以下的季戊四醇与巯基羧酸反应，生成季戊四醇巯基羧酸酯。

6. 发明授权

US07994154B2 Substituted liposaccharides useful in the treatment and prevention of endotoxemia 有权
标题翻译：用于治疗和预防内毒素血症的取代脂肪糖
公开(公告)号：US07994154B2
公开(公告)日：2011-08-09
申请号：US12781166
申请日：2010-05-17
申请人： William J. Christ , Daniel P. Rossignol , Seiichi Kobayashi , Tsutomu Kawata
发明人： William J. Christ , Daniel P. Rossignol , Seiichi Kobayashi , Tsutomu Kawata
IPC分类号： A61K31/70
CPC分类号： C07H15/04 , A61K9/0073 , C07H3/04 , C07H11/00 , C07H15/12
摘要： Novel substituted liposaccharides useful as in the prophylactic and affirmative treatment of endotoxemia including sepsis, septicemia and various forms of septic shock and methods of using these agents are provided. Also provided are methods of preparing these agents and intermediates useful therein.
摘要翻译：提供了用于预防和肯定治疗包括败血症，败血症和各种形式的败血性休克的内毒素血症的新型取代的脂糖和使用这些药剂的方法。还提供了制备这些试剂和在其中有用的中间体的方法。

7. 发明申请

US20110176220A1 Process for Producing Polythiol Compound for Optical Materials, and Polymerizable Composition Containing Polythiol Compound 审中-公开
标题翻译：用于制造光学材料的聚硫醇化合物的方法和含有聚硫醇化合物的可聚合组合物
公开(公告)号：US20110176220A1
公开(公告)日：2011-07-21
申请号：US13075426
申请日：2011-03-30
申请人： Shigetoshi Kuma , Masaru Kawaguchi , Seiichi Kobayashi
发明人： Shigetoshi Kuma , Masaru Kawaguchi , Seiichi Kobayashi
IPC分类号： G02B3/00 , C07C319/14 , C08G18/00
CPC分类号： C07C319/14 , C08G18/3876 , C08G18/7642 , C07C321/14
摘要： Provided is a process for producing a polythiol compound for an optical material, the method includes reacting 2-mercaptoethanol with an epihalohydrin compound to give polyalcohol, and preparing a polythiol compound through the polyalcohol, wherein a content of bis(2-hydroxyethyl)disulfide in the 2-mercaptoethanol is 0.5 wt % or less.
摘要翻译：本发明提供了一种用于制备光学材料用多硫醇化合物的方法，该方法包括使2-巯基乙醇与表卤代醇化合物反应得到多元醇，并通过多元醇制备多硫醇化合物，其中二（2-羟乙基）二硫化物的含量 2-巯基乙醇为0.5重量％以下。

8. 发明申请

US20110124836A1 COMPOSITION, POLYMERIZABLE COMPOSITION, RESIN, OPTICAL COMPONENT, AND METHOD FOR PRODUCING THE COMPOSITION 有权
标题翻译：组合物，可聚合组合物，树脂，光学组分和用于生产组合物的方法
公开(公告)号：US20110124836A1
公开(公告)日：2011-05-26
申请号：US13055494
申请日：2009-07-23
申请人： Tomoyuki Ando , Masakazu Murakami , Mamoru Takashima , Seiichi Kobayashi
发明人： Tomoyuki Ando , Masakazu Murakami , Mamoru Takashima , Seiichi Kobayashi
IPC分类号： C08G79/12 , C07F9/90 , C08G79/00
CPC分类号： C08G18/3876 , C07F9/005 , C07F9/90 , C08G18/73 , C08G18/758 , C08G18/7642 , C08G59/66 , G02B1/041 , C08L75/04 , C08L81/00
摘要： The composition of the present invention contains a product having a thiol group obtained by reacting an Sb or Bi oxide or an Sb or Bi halide with at least one kind of polythiol compounds selected from compounds having at least two thiol groups in a molecule.
摘要翻译：本发明的组合物含有通过使Sb或Bi氧化物或Sb或Bi卤化物与选自分子中具有至少两个硫醇基的化合物中的至少一种多硫醇化合物反应而获得的硫醇基的产物。

9. 发明申请

US20110105427A1 DEAZAPURINES AND USES THEREOF 失效
标题翻译： DEAZAPURINES及其用途
公开(公告)号：US20110105427A1
公开(公告)日：2011-05-05
申请号：US12917669
申请日：2010-11-02
申请人： Jane Daun , Heather A. Davis , Bruce DeCosta , Fabian Gusovsky , Ieharu Hishinuma , Yimin Jiang , Toshihiko Kaneko , Kouichi Kikuchi , Seiichi Kobayashi , André Lescarbeau , Xiang-Yi Li , Kenzo Muramoto , Norihito Ohi , Marc Pesant , Boris M. Seletsky , Motohiro Soejima , Mark Spyvee , Lynda Tremblay , Ye Yao , Hiromitsu Yokohama , Yan (Janet) Zhao , Wanjun Zheng
发明人： Jane Daun , Heather A. Davis , Bruce DeCosta , Fabian Gusovsky , Ieharu Hishinuma , Yimin Jiang , Toshihiko Kaneko , Kouichi Kikuchi , Seiichi Kobayashi , André Lescarbeau , Xiang-Yi Li , Kenzo Muramoto , Norihito Ohi , Marc Pesant , Boris M. Seletsky , Motohiro Soejima , Mark Spyvee , Lynda Tremblay , Ye Yao , Hiromitsu Yokohama , Yan (Janet) Zhao , Wanjun Zheng
IPC分类号： A61K31/437 , A61K31/5377 , A61K31/496 , A61K31/541 , A61K31/4545 , A61K31/444 , A61K31/4709 , A61K31/55 , A61K31/439 , A61K31/4725 , A61K31/695 , A61P29/00 , A61P35/00 , A61P37/06 , A61P17/06 , A61P11/06 , A61P9/00
CPC分类号： A61K31/437 , C07D471/04
摘要： The present invention provides compounds having formula (I): wherein R1, R2, R3 and n are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof in the treatment of inflammatory or autoimmune and proliferative disorders and as inhibitors of cell adhesion molecule expression and inflammatory cytokine signal transduction generally.
摘要翻译：本发明提供了具有式（I）的化合物：其中R 1，R 2，R 3和n如本文中一般和本领域和亚类所述，并且另外提供其药物组合物，及其用于治疗炎症或自身免疫的方法和增殖性疾病以及作为细胞粘附分子表达和炎性细胞因子信号转导的抑制剂。

10. 发明授权

US07868002B2 Deazapurines and uses thereof 有权
标题翻译：脱氮嘌呤及其用途
公开(公告)号：US07868002B2
公开(公告)日：2011-01-11
申请号：US11906056
申请日：2007-09-28
申请人： Jane Daun , Heather A. Davis , Bruce DeCosta , Fabian Gusovsky , Ieharu Hishinuma , Yimin Jiang , Toshihiko Kaneko , Kouichi Kikuchi , Seiichi Kobayashi , André Lescarbeau , Xiang-Yi Li , Kenzo Muramoto , Norihito Ohi , Marc Pesant , Boris M. Seletsky , Motohiro Soejima , Mark Spyvee , Lynda Tremblay , Ye Yao , Hiromitsu Yokohama , Yan (Janet) Zhao , Wanjun Zheng
发明人： Jane Daun , Heather A. Davis , Bruce DeCosta , Fabian Gusovsky , Ieharu Hishinuma , Yimin Jiang , Toshihiko Kaneko , Kouichi Kikuchi , Seiichi Kobayashi , André Lescarbeau , Xiang-Yi Li , Kenzo Muramoto , Norihito Ohi , Marc Pesant , Boris M. Seletsky , Motohiro Soejima , Mark Spyvee , Lynda Tremblay , Ye Yao , Hiromitsu Yokohama , Yan (Janet) Zhao , Wanjun Zheng
IPC分类号： C07D413/14 , C07D471/02 , A61K31/4745 , A61K31/5377 , A61P11/06 , A61P19/02 , A61P25/00 , A61P3/10 , A61P9/00
CPC分类号： A61K31/437 , C07D471/04
摘要： As discussed above, there remains a need for the development of novel therapeutic agents useful for treating inflammatory or autoimmune and proliferative diseases. The present invention provides novel compounds of general formula (I), and pharmaceutical compositions thereof, as described generally and in classes and subclasses herein, as well as methods of making and using such compounds.
摘要翻译：如上所述，仍然需要开发可用于治疗炎性或自身免疫性和增殖性疾病的新型治疗剂。本发明提供了通式（I）的新型化合物及其药物组合物，如本文中一般和本课程和亚类所述，以及制备和使用这些化合物的方法。

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