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1. 发明申请

WO2023078853A1 INJECTION DEVICE AND METHOD OF UNLOCKING OPERATION OF THE INJECTION DEVICE 审中-公开
公开(公告)号：WO2023078853A1
公开(公告)日：2023-05-11
申请号：PCT/EP2022/080409
申请日：2022-11-01
申请人： SANOFI
发明人： ALT, Stefan , GLÄSSER, Tim , HELMER, Michael , MÜCKE, Stephan , NOBER, Peter , SCHABBACH, Michael , VITT, Martin
IPC分类号： A61M5/315
摘要： The present disclosure relates to an injection device and to a method of unlocking operation of the injection device. The injection device comprises: - a housing (11) of elongated shape and extending along a longitudinal direction (z), wherein the housing (11) comprises a distal housing component (12) and a proximal housing component (14), wherein the distal housing component (12) is configured to accommodate a medicament container (30) and wherein the proximal housing component (14) is configured to accommodate or to support a drive mechanism (8) to operably engage with the medicament container (30) for expelling or withdrawing of the dose of the medicament (4) from the medicament container (30), - the drive mechanism (8) to operably engage with the medicament container (30), - an electronic unit (70) coupled to the drive mechanism (8), - an electric sensor (150) provided at or near a distal end of the proximal housing component (14), electrically connected to the electronic unit (70) and configured to contactlessly detect an electric identifier (50) provided on or in one of the medicament container (30) and the distal housing component (12).

2. 发明申请

WO2023078849A1 INJECTION DEVICE AND METHOD OF UNLOCKING OPERATION OF THE INJECTION DEVICE 审中-公开
公开(公告)号：WO2023078849A1
公开(公告)日：2023-05-11
申请号：PCT/EP2022/080405
申请日：2022-11-01
申请人： SANOFI
发明人： ALT, Stefan , HELMER, Michael , SCHABBACH, Michael , VITT, Martin
IPC分类号： A61M5/315
摘要： The present disclosure relates to an injection device and to a method of unlocking operation of the injection device. The injection device comprises: - a housing (11) configured to accommodate a medicament container (30), - a drive mechanism (8) operably engageable with the medicament container (30) for expelling or withdrawing the dose of the medicament (4) from the medicament container (30), wherein the drive mechanism (8) comprises at least one interlock (90, 91, 92, 93) configured to disable at least one of setting of the dose and dispensing of the dose, - an identifier (50) provided on or associated with the medicament container (30), - an electronic unit (70) operable to control the at least one interlock (90, 91, 92, 93) and comprising a near field communication interface (78) for obtaining information being indicative of the identifier (50) and wherein the electronic unit (70) is configured to process signals of the near field communication interface (78) to at least temporally deactivate the at least one interlock (90, 91, 92, 93).

3. 发明申请

WO2023280419A1 DATA COLLECTION APPARATUS FOR DOSE DETERMINATION 审中-公开
公开(公告)号：WO2023280419A1
公开(公告)日：2023-01-12
申请号：PCT/EP2021/069124
申请日：2021-07-09
申请人： SANOFI
发明人： SCHABBACH, Michael , ZHITOMIRSKI, Victor , MISCHO, Horst
IPC分类号： A61M5/24 , A61M5/315
摘要： A data collection apparatus for measuring a dose of medicament comprises a gyroscope configured to detect rotation of a dose dialling component of a drug delivery device during at least one of a dose dialling operation and a dose dispensing operation and output a signal corresponding to the amount of rotation; and a mode sensing arrangement configured to output a signal indicative of whether the dose dialling operation or the dose dispensing operation is being performed on the drug delivery device.

4. 发明申请

WO2021001254A1 AWAKENING ELECTRONICS IN AN INJECTION DEVICE 审中-公开
公开(公告)号：WO2021001254A1
公开(公告)日：2021-01-07
申请号：PCT/EP2020/067851
申请日：2020-06-25
申请人： SANOFI
发明人： SCHABBACH, Michael , ALPERS, Johannes , APPUSAMY VEDHACHALAM, Ganesh , BIGALKE, Jörg , RAUSCH, Martin , BACCARO, Anna
IPC分类号： A61M5/31 , A61M5/32 , A61M5/50 , G16H20/17
摘要： An injection device (102) comprising: an energy source (104) configured to power an electronic system (105) of the injection device (102); one or more sensors (127a, 127b, 28b) in communication with the energy source (104), the one or more sensors (127a, 27b, 128b) configured to cause an activation signal to be provided to the energy source (104) to cause the energy source (104) to enter a powered state from a sleep state; and a processor (128a) configured to facilitate one or more functions of the injection device (102) when the injection device (102) is in the powered state.

5. 发明申请

WO2019101962A1 MEDICAMENT INJECTION DEVICE WITH ROTARY ENCODER 审中-公开
公开(公告)号：WO2019101962A1
公开(公告)日：2019-05-31
申请号：PCT/EP2018/082438
申请日：2018-11-23
申请人： SANOFI
发明人： SCHABBACH, Michael , MORRIS, Anthony Paul , SMITH, Ronald Antony , MOLYNEUX, Brian Charles , DRAPER, Paul Richard , MASON, Craig Ashley , GAZELEY, Oliver Charles , CLARK, David Edward , PLUMPTRE, David Aubrey , O'HARE, Aidan Michael , THOMAS, Richard James , KRAMER, Felix , WYSS, Beat , MÜLLER, Philipp
IPC分类号： A61M5/24
CPC分类号： A61M5/24 , A61M5/31551 , A61M2205/3306 , A61M2205/3317 , A61M2205/3561 , A61M2205/50 , A61M2205/8212
摘要： The present disclosure relates to medicament injection devices. According to a first aspect, this disclosure describes an injection device comprising: a movable dosage programming component comprising a rotary encoder system having a predefined angular periodicity; a sensor arrangement comprising a first optical sensor configured to detect movement of the movable dosage programming component relative to the sensor arrangement during dosing of a medicament, wherein the first optical sensor is configured to operate in a strobe-sampling mode at a first frequency; a second optical sensor configured to detect movement of the rotary encoder system relative to the second optical sensor wherein the second optical sensor is configured to operate in a strobe-sampling mode at a second frequency lower than the first frequency; and a processor arrangement configured to, based on said detected movement, determine a medicament dosage administered by the injection device.

6. 发明申请

WO2019096904A1 MIXING AND/OR RECONSTITUTION SYSTEM 审中-公开
公开(公告)号：WO2019096904A1
公开(公告)日：2019-05-23
申请号：PCT/EP2018/081369
申请日：2018-11-15
申请人： SANOFI
发明人： SCHABBACH, Michael , HARVEY, Charlotte Emma , HUANG, Congyi , FREARSON, Timothy Charles , NORMAN, Alexander David , POTTER, Andrew Robert , STACEY, Gary
IPC分类号： A61M5/178
CPC分类号： A61M5/1782 , A61J1/2096 , A61M5/19 , A61M5/20 , A61M5/2053 , A61M5/2066 , A61M5/2448 , A61M5/31596 , A61M5/445 , A61M2005/2013 , A61M2005/2474 , A61M2005/3128 , A61M2005/31598 , A61M2005/3267 , A61M2205/0272 , A61M2209/04 , A61M2209/045
摘要： The invention refers to a mixing and/or reconstitution system which reduces the possibility of user error and provides an easy and automatic operation comprising -a device(300, 400) containing a first material within a first chamber (305, 405), further comprising a housing (301, 401) and a plunger (307, 407), -a vial (308, 408) containing a second material within a second chamber (309, 409), wherein at least one of the first material and the second material is a fluid, -a base station (350, 450) comprising at least one drive unit (370, 470), a first slide (374) and a driver, and -a needle (302, 402), wherein the device (300, 400) and the vial (308, 408) are attachable to the base station in an initial position in which the device (300, 400) and the vial (308, 408) have a pre-defined distance to each other, wherein the needle (302, 402) is attached to the device (300, 400) and fluidly connected with the first chamber (305, 405) of the device (300, 400), wherein in the initial position the at least one drive unit (370, 470) is connected to the first slide (374) that moves the vial (308, 408) and/or the housing (301, 401) of the device (300, 400) relative to each other in an axial direction of the device (300, 400) along a pre-defined distance into an activated position, in which the needle (302, 402) is fluidly connected with the second chamber (309, 409) and wherein in the activated position the at least one drive unit (370, 470) is connected to the driver that moves the plunger (307, 407) in the axial direction of the device (300, 400) along a pre- defined distance such that during fluid connection of the needle (302, 402) with the second chamber (309, 409) the first material is expelled from the first chamber (305, 405) of the device into the second chamber (309, 409) of the vial (308, 408) or the second material is expelled from the second chamber (309, 409) of the vial (308, 408) into the first chamber (305, 405) of the device (300, 400). The invention further refers to a base station thereto, a supporting unit and a respective mixing and/or reconstitution method.

7. 发明申请

WO2018202663A1 CARTRIDGE FOR DOSAGE SENSING 审中-公开
公开(公告)号：WO2018202663A1
公开(公告)日：2018-11-08
申请号：PCT/EP2018/061114
申请日：2018-05-02
申请人： SANOFI
发明人： SCHABBACH, Michael , DETTE, Christoph , ALLERDINGS, Alexander , OTTEN, Martin , HAMMEN, Dietmar , POMMEREAU, Christian , JANSEN, Paul Edward , BRUEGGEMANN, Ulrich
IPC分类号： A61M5/20
摘要： An injection device (100) is provided, comprising a cartridge (102) configured to hold a volume of fluid, the cartridge (102) having a proximal end (106) and a distal end (104a, 104b) through which the fluid is dispensed; a first stopper (108) disposed in the cartridge (102) and configured to move from the proximal end (106) toward the distal end (104a, 104b) to cause the fluid to be dispensed through the distal end (104a, 104b) of the cartridge (102); a second stopper (115) disposed at the distal end (104a, 104b) of the cartridge (102), the second stopper (115) including an aperture (119) through which the fluid is dispensed; a reflector (120a, 120b) disposed at the distal end (104a, 104b) of the cartridge (102); and a transmitter (122) and a receiver (124) disposed in the first stopper (108), the transmitter (122) configured to transmit one or more waves toward the reflector (120a, 120b) and the receiver (124) configured to receive reflections of the one or more waves from at least the reflector (120a, 120b).

8. 发明申请

WO2018108855A1 Data collection from a medicament delivery device 审中-公开
公开(公告)号：WO2018108855A1
公开(公告)日：2018-06-21
申请号：PCT/EP2017/082311
申请日：2017-12-12
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： SCHABBACH, Michael , FRANKE, Beate
IPC分类号： A61M5/315 , G06F19/00 , G16H10/60 , G06T7/73 , G06T7/77 , G06T7/70 , G06T7/90 , G06K9/32 , A61M5/31
摘要： Detecting status changes in a medicament delivery device. A data collection apparatus comprises: a camera configured to obtaining first and second recordings of at least a portion of a medicament delivery device using a camera, said portion including a first component and a second component, the first component being configured to move relative to the second component as medicament is expelled from the medicament delivery device; and a processing arrangement configured: to determine, from said first and second recordings, positions in the first and second recordings of the first component relative to the second component, and to determine an amount of medicament that has been expelled by the medicament delivery device by comparing the position in the first recording of the first component relative to the second component in the first recording with a position in the second recording of the first component relative to the second component in the second recording, the second recording having been captured at a different time to the first recording.

9. 发明申请

WO2018029238A1 MEDICAMENT DELIVERY DEVICE 审中-公开
标题翻译：药物输送装置
公开(公告)号：WO2018029238A1
公开(公告)日：2018-02-15
申请号：PCT/EP2017/070154
申请日：2017-08-09
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： SCHABBACH, Michael , FRANKE, Beate , NELSON, Andrew , PRADEL, Giuliano
IPC分类号： A61M5/142 , A61M5/145 , A61M5/158
摘要： A medicament delivery device comprises a needle for delivering a medicament; and an insertion mechanism configured to urge the needle in a first direction parallel to a longitudinal axis of the needle; wherein the insertion mechanism comprises a driving mechanism which is configured to exert a force in a second direction perpendicular to the first direction, and a cam which is coupled to the needle and is configured to receive a force from the driving mechanism and move in the first direction in response to the received force.
摘要翻译：药物输送装置包括用于输送药物的针头; 以及插入机构，所述插入机构构造成沿平行于所述针的纵向轴线的第一方向推动所述针; 其中，所述插入机构包括驱动机构和驱动机构，所述驱动机构构造成在与所述第一方向垂直的第二方向上施加力，所述凸轮联接到所述针并且构造成接收来自所述驱动机构的力并且在所述第一回应所收到的力量。

10. 发明申请

WO2015091761A1 DISPOSABLE CARTRIDGE FOR A DRUG DELIVERY DEVICE 审中-公开
标题翻译：用于药物递送装置的便携式药盒
公开(公告)号：WO2015091761A1
公开(公告)日：2015-06-25
申请号：PCT/EP2014/078413
申请日：2014-12-18
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： SCHABBACH, Michael , WERNER, Meinolf , ZECKAI, Olaf
IPC分类号： A61M5/152 , A61J1/10 , A61J1/14 , A61M5/142
CPC分类号： A61M5/1483 , A61M5/14228 , A61M5/14232 , A61M5/152 , A61M5/158 , A61M2205/12
摘要： The present invention relates to a disposable cartridge for a drug delivery device, the cartridge comprising: - a flexible bag (81; 181 ) to accommodate a liquid medicament and having an opening (81a, 181a) adjacent to a sidewall (81b, 181b), a socket (76, 176) having a fluid channel (86; 186) in fluid communication with a cartridge fluid coupling (90; 190), wherein the socket (76, 176) extends into the opening (81a, 181 a) of the flexible bag (81; 181), a housing (71; 171) covering at least a portion of the flexible bag (81; 181) and having a receptacle (71a, 171a) to receive the socket (76; 176) with the flexible bag (81; 181), wherein the flexible bag's (81; 181) sidewall (81b; 181b) is fixed between the socket (76; 176) and the receptacle (71a, 171a).
摘要翻译：本发明涉及一种用于药物输送装置的一次性药筒，所述药筒包括： - 柔性袋（81; 181），用于容纳液体药物并且具有邻近侧壁（81b，181b）的开口（81a，181a）具有与盒式液体联接器（90; 190）流体连通的流体通道（86; 186）的插座（76,176），其中所述插座（76,176）延伸到所述开口（81a，181a）的开口所述柔性袋（81; 181），覆盖所述柔性袋（81; 181）的至少一部分并具有容纳所述插座（76; 176）的容器（71; 171a）的壳体（71; 171）柔性袋（81; 181），其中所述柔性袋（81; 181）侧壁（81b; 181b）固定在所述插座（76; 176）和所述插座（71a，171a）之间。

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