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1. 发明申请

WO2012130703A1 DOSE SETTING MECHANISM AND INJECTION DEVICE 审中-公开
标题翻译：剂量设定机构和注射装置
公开(公告)号：WO2012130703A1
公开(公告)日：2012-10-04
申请号：PCT/EP2012/055054
申请日：2012-03-22
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , PLUMPTRE, David, Aubrey
发明人： PLUMPTRE, David, Aubrey
IPC分类号： A61M5/24 , A61M5/315
CPC分类号： A61M5/31535 , A61M5/24 , A61M5/31525 , A61M5/31528 , A61M5/3155 , A61M5/31551 , A61M5/31555 , A61M5/31585
摘要： A dose setting mechanism (1) for a drug delivery device is provided comprising a dose setting member (3), a drive member (4), a clutch (5a, 5b), a first clicker (6') and second clicker (6''). The first clutch (5a, 5b) and a second clutch (10, 11) are designed and adapted to each other such that at any time during operation either the first clutch (5a, 5b) rotationally couples the dose setting member (3) and the drive member (4) and/or the second clutch (10, 11) rotationally couples the drive member (4) and the first clicker component (6'). Further, the invention refers to an injection device with such a dose setting mechanism.
摘要翻译：提供了一种用于药物输送装置的剂量设定机构（1），其包括剂量设定部件（3），驱动部件（4），离合器（5a，5b），第一打卡器（6'）和第二打印器 ''）。第一离合器（5a，5b）和第二离合器（10,11）被设计和彼此适配，使得在操作期间的任何时候，第一离合器（5a，5b）将剂量设定构件（3）和所述驱动构件（4）和/或所述第二离合器（10,11）旋转地联接所述驱动构件（4）和所述第一击打构件（6'）。此外，本发明涉及具有这种剂量设定机构的注射装置。

2. 发明申请

WO2022090274A1 ELECTRONIC SYSTEM FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE 审中-公开
公开(公告)号：WO2022090274A1
公开(公告)日：2022-05-05
申请号：PCT/EP2021/079747
申请日：2021-10-27
申请人： SANOFI
发明人： ALT, Stefan , GAZELEY, Oliver, Charles , HARVEY-COOK, Adam, Moyo , INGRAM, Stephen , MASON, Craig, Ashley , O'HARE, Aidan, Michael , PLUMPTRE, David, Aubrey
IPC分类号： A61M5/315
摘要： 62 PAT20006-WO-PCT Abstract 5 Electronic system for a drug delivery device and drug delivery device An electronic system (1000) for a drug delivery device (1) is provided, the electronic system comprising: at least one user interface member (1600) configured to be manipulated by a user for performing a dose operation, e.g. a dose setting operation to set a dose of drug to be 10 delivered by the drug delivery device and/or a dose delivery operation for delivering a set dose, an electronic control unit (1100), the electronic control unit being configured to control operation of the electronic system, the electronic system having a first state and a second state, wherein the electronic system has an increased electrical power consumption in the second state as compared to the first state, an electrical signaling unit (1300), the signaling unit being configured 15 to provide an electrical signal indicative that the user interface member is being manipulated, wherein the electronic control unit is configured to switch the electronic system from the first state into the second state in response to the electrical signal, and wherein the user interface member comprises a first portion (1603) and a second portion (1604), wherein the first portion is movable relative to the second portion from a rest position of the first portion to a signaling 20 position of the first portion, wherein the signaling unit is configured to provide the electrical signal in response to the movement of the first portion relative to the second portion from the rest position into the signaling position. Figure 7A 25

3. 发明申请

WO2014139917A1 ASSEMBLY FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE WITH SUCH AN ASSEMBLY 审中-公开
标题翻译：用于具有这种组装的药物递送装置和药物递送装置的组装
公开(公告)号：WO2014139917A1
公开(公告)日：2014-09-18
申请号：PCT/EP2014/054529
申请日：2014-03-10
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： PLUMPTRE, David, Aubrey , DRAPER, Paul, Richard , MERCER, David, Richard , REKAYA, Naceur , GRIFFIN, Paul
IPC分类号： A61M5/31 , A61M5/14
CPC分类号： A61M5/3146 , A61M5/31551 , A61M5/3158 , A61M2005/3126 , A61M2205/6018
摘要： The present disclosure pertains to an assembly for a drug delivery device (1) comprising a housing part (10), a piston rod (17) displaceable relative to the housing part (10), a first sleeve member (6) and a second sleeve member (7). First and second sleeve members (6, 7) are coupled to the housing part (10). In an initial state of the assembly the first sleeve member (6) is movable from an initial position to a second position relative to the second sleeve member (7) which allows the piston rod (17) to axially travel from an initial position to a predetermined second position such that the assembly is in a primed state. Moreover, in the primed state of the assembly, with the first sleeve member (6) being in the second position relative to the second sleeve member (7), first and second sleeve members (6, 7) are permanently rotationally and axially locked to each other by a first engagement feature (9) such that first and second sleeve members (6, 7) together form a sleeve (14). Additionally, a drug delivery device (1) with such an assembly is described.
摘要翻译：本公开涉及用于药物输送装置（1）的组件，其包括壳体部分（10），相对于壳体部分（10）可移位的活塞杆（17），第一套筒构件（6）和第二套筒会员（7）。第一和第二套筒构件（6,7）联接到壳体部分（10）。在组件的初始状态下，第一套筒构件（6）能够相对于第二套筒构件（7）从初始位置移动到第二位置，从而允许活塞杆（17）从初始位置轴向移动到预定的第二位置，使得组件处于起动状态。此外，在组件的底漆状态下，第一套筒构件（6）相对于第二套筒构件（7）处于第二位置，第一和第二套筒构件（6,7）永久地旋转并轴向锁定到彼此通过第一接合特征（9），使得第一和第二套筒构件（6,7）一起形成套筒（14）。另外，描述了具有这种组件的药物输送装置（1）。

4. 发明申请

WO2021255215A1 SYSTEM FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE 审中-公开
公开(公告)号：WO2021255215A1
公开(公告)日：2021-12-23
申请号：PCT/EP2021/066529
申请日：2021-06-18
申请人： SANOFI
发明人： PLUMPTRE, David, Aubrey , VEASEY, Robert , GRIFFIN, Paul , HAWKINS, Rory, James, Livingston , BERTINAT, Charles, Henry
IPC分类号： A61M5/24 , A61M2005/2407 , A61M2005/2477 , A61M2005/2488
摘要： The present invention refers to a system for a drug delivery device comprising a housing (1, 8) and a cartridge holder (2, 2a, 2b, 2c, 2d, 2e, 2f, 2g) which may contain a cartridge (13) filled with a medicament. The housing (1, 8) and the cartridge holder (2, 2a) comprise a coding interface (5, 6) for dedicating a certain cartridge (2a) to a certain housing (1, 8) and a bayonet type attachment interface (3, 4) for releasably attaching the cartridge holder (2, 2a) to the housing (1, 8) by an attachment movement comprising a first stage and a second stage. The system further comprises at least one compliant spring member (7, 17,19, 21) arranged and designed such that it is strained during the first and/or the second stage of the attachment movement at least if the housing coding element (6) does not match the holder coding element (5), and wherein the compliant spring member (7, 17,19, 21) is arranged and designed to move the cartridge holder (2, 2a) relative to the housing (1, 8) in a direction contrary to the attachment movement when relaxing.

5. 发明申请

WO2015032777A1 DRIVE MECHANISM FOR A DRUG DELIVERY DEVICE 审中-公开
标题翻译：用于药物递送装置的驱动机构
公开(公告)号：WO2015032777A1
公开(公告)日：2015-03-12
申请号：PCT/EP2014/068650
申请日：2014-09-03
申请人： SANOFI
发明人： BILTON, Simon, Lewis , VEASEY, Robert , JONES, Matthew , PLUMPTRE, David, Aubrey , MARSH, William , BAINTON, Michael , HIGGINS, Daniel, David
IPC分类号： A61M5/315
CPC分类号： A61M5/31551 , A61M5/31511 , A61M5/31553 , A61M5/31568 , A61M5/31583 , A61M5/31585 , A61M2205/581 , A61M2205/582
摘要： A drive mechanism (1) for use in a drug delivery device (100) is provided. The drive mechanism (1) comprises a housing (10, 11, 12, 14, 15) with a proximal and a distal end and a piston rod (22) which is rotatable with respect to the housing (10, 11, 12, 14, 15). The drive mechanism (1) further comprises a nut member (31) which is selectively rotationally lockable with respect to the housing (10, 11, 12, 14, 15), wherein the drive mechanism (1) is switchable between a setting mode of operation and a dispensing mode of operation. The drive mechanism (1) is configured such that in the setting mode of operation, the nut member (31) and the piston rod (22) are rotatable with respect to the housing (10, 11, 12, 14, 15), and in the dispensing mode of operation, the piston rod (22) is rotatable with respect to the housing (10, 11, 12, 14, 15) and the nut member (31) is rotationally locked with respect to the housing (10, 11, 12, 14, 15), wherein, when the piston rod (22) rotates, the piston rod (22) moves distally with respect to the nut member (31).
摘要翻译：提供了一种用于药物输送装置（100）的驱动机构（1）。驱动机构（1）包括具有近端和远端的壳体（10,11,12,14,15）和可相对于壳体（10,11,12,14和15）旋转的活塞杆（22），15）。驱动机构（1）还包括螺母构件（31），该螺母构件相对于壳体（10,11,12,14,15）选择性地可旋转地锁定，其中驱动机构（1）可以在操作和分配操作模式。驱动机构（1）构造成使得在设定操作模式下，螺母构件（31）和活塞杆（22）能够相对于壳体（10,11,12,14,15）旋转，并且在分配操作模式中，活塞杆（22）能够相对于壳体（10,11,12,14,15）旋转，并且螺母构件（31）相对于壳体（10,11）旋转地锁定，12,14,15），其中，当活塞杆（22）旋转时，活塞杆（22）相对于螺母构件（31）向远侧移动。

6. 发明申请

WO2021224289A1 SUPPLEMENTAL DEVICE FOR AN INJECTION DEVICE 审中-公开
公开(公告)号：WO2021224289A1
公开(公告)日：2021-11-11
申请号：PCT/EP2021/061773
申请日：2021-05-05
申请人： SANOFI
发明人： HARVEY-COOK, Adam, Moyo , PLUMPTRE, David, Aubrey , GAZELEY, Oliver, Charles , VEASEY, Robert , O'HARE, Aidan, Michael
IPC分类号： A61M5/20 , A61M5/31
摘要： A supplemental device is configured to be coupled to an injection device, the supplemental device comprising a sensor arrangement and a processor arrangement, wherein the processor arrangement is configured to cause the supplemental device to use the sensor arrangement to sense an identification feature of the injection device and to determine a type of the injection device based on the sensed identification feature.

7. 发明申请

WO2021214275A1 ELECTRONIC MODULE AND DRUG DELIVERY DEVICE 审中-公开
公开(公告)号：WO2021214275A1
公开(公告)日：2021-10-28
申请号：PCT/EP2021/060631
申请日：2021-04-23
申请人： SANOFI
发明人： HARVEY-COOK, Adam, Moyo , EARWALKER, Tom, Alexander , PLUMPTRE, David, Aubrey , GAZELEY, Oliver, Charles , VEASEY, Robert , MASON, Craig, Ashley
IPC分类号： A61M5/20 , A61M5/24 , A61M5/315
摘要： The present invention refers to an electronic module (11) for releasable attachment to a drug delivery device (1) and to such a drug delivery device. The module (11) may comprise at least one module lockout form (323) adapted for mating abutment with a corresponding device lockout form (21) of a dedicated a drug delivery device (1). Further, the module (11) may comprise at least one attachment element (324) for releasable attachment of the module (11) on a drug delivery device (1). Further, the module (11) may comprise at least one light pipe (325) for guiding a light beam from a light source (121) to a reflective surface (24) of the drug delivery device (1) and from said reflective surface (24) to a light detector sensor (122). Still further, the module (11) may comprise at least one light guide (321) for guiding a light beam from a light source (141) to a user feedback surface (322) of said component adapted to emit light. Further, the module (11) may comprise at least one elastically deformable switch arm (326). The component (320) may be a unitary component part injection molded from a polycarbonate material.

8. 发明申请

WO2021191322A1 ELECTRONIC SYSTEM FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE 审中-公开
公开(公告)号：WO2021191322A1
公开(公告)日：2021-09-30
申请号：PCT/EP2021/057665
申请日：2021-03-25
申请人： SANOFI
发明人： MARSH, William, Geoffrey, Arthur , MORRIS, Anthony, Paul , EARDLEY, Zoë, Georgina , DRAPER, Paul, Richard , VEASEY, Robert , PLUMPTRE, David, Aubrey , GAZELEY, Oliver, Charles , SMITH, Ronald, Antony
IPC分类号： A61M5/20 , A61M5/24 , A61M5/315
摘要： An electronic system (1000) for a drug delivery device (1, 2) is provided, the electronic system comprising: - a dose setting and drive mechanism (1780, 1790) which is configured to perform a dose setting operation for setting a dose to be delivered by the drug delivery device and a dose delivery operation for delivering the set dose, the dose setting and drive mechanism comprising a first member (1780) and a second member (1790), wherein the dose setting and drive mechanism is configured such that, in the dose delivery operation and/or in the dose setting operation, the first member moves, e.g. rotates, relative to the second member, - an electronic control unit (1100) configured to control an operation of the electronic system, the electronic system having a first state and a second state, wherein the electronic system has an increased electrical power consumption in the second state as compared to the first state, - an electrical use detection unit (1300), the electrical use detection unit being operatively connected to the electronic control unit, the electrical use detection unit being configured to generate a use signal which is indicative that the user has commenced the dose setting operation or the dose delivery operation, wherein the electronic system is configured such that it is switched from the first state into the second state by the electronic control unit in response to the use signal, and wherein the electrical use detection unit is configured to generate the use signal in response to the relative movement, e.g. in response to the relative rotational movement, between the first member and the second member, preferably during the dose delivery operation.

9. 发明申请

WO2021116388A1 ELECTRONIC MODULE AND MODULAR SYSTEM FOR A DRUG DELIVERY DEVICE 审中-公开
公开(公告)号：WO2021116388A1
公开(公告)日：2021-06-17
申请号：PCT/EP2020/085729
申请日：2020-12-11
申请人： SANOFI
发明人： HARVEY-COOK, Adam, Moyo , PLUMPTRE, David, Aubrey , GAZELEY, Oliver, Charles , VEASEY, Robert
IPC分类号： A61M5/20 , A61M5/24
摘要： The present disclosure relates to an electronic module (320; 420; 520; 620) configured for attachment to a proximal end (P) of a drug delivery device (100) in a predefined fastening configuration, the drug delivery device (100) comprising an elongated housing extending in a longitudinal direction and comprising a distal end (D) and the proximal end (P), the electronic module (320; 420; 520; 620) comprising: - a mechanical coding (350; 450; 550; 650) comprising a mechanical coding feature (351; 451; 551; 651) to engage with a mechanical counter coding feature (371; 471; 571; 671) of a mechanical counter coding (370; 470; 570; 670) provided at the proximal end (P) of the drug delivery device (100), - wherein one of the mechanical coding feature (351; 451; 551; 651) and the mechanical counter coding feature (371; 471; 571; 671) comprises a protrusion (352; 452; 552; 652) extending in the longitudinal direction and wherein the other one of the mechanical coding feature (351; 451; 551; 651) and the mechanical counter coding feature (371; 471; 571; 671) comprises a recess (372; 472; 572; 672), - wherein when a geometric shape of the protrusion (352; 452; 552; 652) is not matching with a geometric shape of the recess (372; 472; 572; 672), or - when a position of the protrusion (352; 452; 552; 652) in a plane transverse to the longitudinal direction is not matching with a position of the recess (372; 472; 572; 672) in the transverse plane, or - when a longitudinal extent of the protrusion (352; 452; 552; 652) is larger than a longitudinal extent of the recess (372; 472; 572; 672), the mechanical coding (350; 450; 550; 650) and the mechanical counter coding (370; 470; 570; 670) being operable to prevent a fastening of the electronic module (320; 420; 520; 620) to the proximal end (P) of the drug delivery device (100) in the predefined fastening configuration.

10. 发明申请

WO2012130704A1 DRUG DELIVERY DEVICE 审中-公开
标题翻译：药物递送装置
公开(公告)号：WO2012130704A1
公开(公告)日：2012-10-04
申请号：PCT/EP2012/055056
申请日：2012-03-22
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , PLUMPTRE, David, Aubrey , SMITH, Christopher, James
发明人： PLUMPTRE, David, Aubrey , SMITH, Christopher, James
IPC分类号： A61M5/24 , A61M5/315
CPC分类号： A61M5/31528 , A61M5/24 , A61M5/3146 , A61M5/31543 , A61M5/31573 , A61M2005/2488 , A61M2005/3142 , A61M2005/3152 , A61M2205/581 , A61M2205/582
摘要： A resettable drug delivery device (1) is provided comprising a body (9, 11), a cartridge holder (7) for receiving a cartridge (8), and means (13, 14, 17, 18) for releasably coupling the cartridge holder (7) to the body (9, 11) or the dose setting mechanism. During an initial rotational coupling movement of the cartridge holder (7) relative to the body (9, 11) or the dose setting mechanism the cartridge holder (7) is caused to move in a first axial direction relative to the body (9, 11) or the dose setting mechanism and during a continued rotational coupling movement of the cartridge holder (7) relative to the body (9, 11) or the dose setting mechanism the cartridge holder (7) is caused to move in a second, contrary axial direction.
摘要翻译：提供了一种可重置药物输送装置（1），其包括主体（9,11），用于容纳盒（8）的盒保持器（7）和用于可释放地联接盒保持器的装置（13,14,17,18）（7）到身体（9,11）或剂量设定机构。在盒保持器（7）相对于主体（9,11）或剂量设定机构的初始旋转联接运动期间，使盒保持器（7）相对于主体（9,11）在第一轴向方向上移动）或剂量设定机构，并且在盒保持器（7）相对于本体（9,11）或剂量设定机构的连续旋转联接运动期间，使盒保持器（7）在第二相反的轴向方向。

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