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    • 10. 发明申请
    • HYDROXYPHENYLALKADIONES AND THEIR USE FOR MASKING BITTER TASTE AND/OR FOR INTENSIFYING SWEET TASTE
    • 羟基苯甲醛和它们用于掩盖苦味和/或用于强化甜味剂的用途
    • WO2007003527A1
    • 2007-01-11
    • PCT/EP2006/063576
    • 2006-06-27
    • SYMRISE GMBH & CO. KGLEY, JakobBERTRAM, Heinz-JürgenKRAMMER, GerhardKINDEL, Günter
    • LEY, JakobBERTRAM, Heinz-JürgenKRAMMER, GerhardKINDEL, Günter
    • A23L1/226C07C49/00
    • C07C49/258A23F3/405A23L2/56A23L27/20A23L27/84A23L27/86C07C45/62C07C45/74C07C49/245C07C49/248C07C49/255
    • The use of a hydroxyphenylalkadione derivative of the formula (I) wherein, for X, a and Y: X is a -CH 2 -, -NH- or -O- group, Y is a -CH 2 - group and a is a single bond or X and Y are in each case a -CH- group and a is a double bond in the Z or E configuration, wherein, for R 1 , R 2 and R 3 R 1 denotes hydrogen, an aliphatic radical having 1 to 4 C atoms or a -O-R 5 , -S-R 5 or -NR 5 R 6 group and R 2 and R 3 independently of one another denote hydrogen or an alkyl having 1, 2, 3, 4 or 5 C atoms which is optionally substituted by one or more oxo groups or R 7 -O- groups or R 1 and R 2 together form an aliphatic ring which contains a total of 4 to 10 carbon atoms and 0 or 1 oxygen atom, wherein the ring constituent represented by R 1 and R 2 is optionally substituted by one or more oxo groups and/or R 7 -O- groups and/or aliphatic radicals having 1 to 4 C atoms and R 3 denotes hydrogen or an alkyl having 1, 2, 3, 4 or 5 C atoms which is optionally substituted by one or more oxo groups or R 7 -O- groups or R 2 and R 3 together form an aliphatic ring which contains a total of 4 to 10 carbon atoms and 0 or 1 oxygen atom, wherein the ring constituent represented by R 2 and R3 is optionally substituted by one or more oxo groups and/or R 7 -O- groups and/or aliphatic radicals having 1 to 4 C atoms and R 1 denotes hydrogen, an aliphatic radical having 1 to 4 C atoms or a -O-R 5 , -S-R 5 or -NR 5 R 6 group, wherein, for R 4 and R: R 4 and R independently of one another denote hydrogen, methyl or ethyl and wherein, for R 5 , R 6 and R 7 : R 5 R 6 and R 7 independently of one another denote hydrogen or an aliphatic radical having 1 to 4 C atoms, a salt of such a hydroxyphenylalkadione of the formula (I), a mixture comprising or consisting of two or more different hydroxy- phenylalkadiones of the formula (I), wherein X, a, Y, R, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 and R 7 in each case have the meaning given above, a mixture comprising or consisting of salts of two or more different hydroxyphenylalkadiones of the formula (I), wherein X, a, Y, R, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 and R 7 in each case have the meaning given above, or a mixture comprising or consisting of a hydroxyphenylalkadione of the formula (I) or two or more different hydroxyphenylalkadiones of the formula (I), wherein X, a, Y, R, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 and R 7 in each case have the meaning given above, and a salt of a hydroxyphenylalkadione of the formula (I) or two or more salts of different hydroxyphenylalkadiones of the formula (I), wherein X, a, Y, R, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 and R 7 in each case have the meaning given above, for modifying, masking or reducing the unpleasant flavour impression of an unpleasantly tasting substance and/or for intensifying the sweet taste of a sweet-tasting substance and/or the sweet odour impression of an aroma substance which causes a sweet odour impression, as well as formulations and processes including a hydroxyphenylalkadione of the formula (I), are described.
    • 使用式(I)的羟基苯基二酮衍生物,其中,对于X,a和Y:X为-CH 2 - , - NH-或-O-基团,Y为-CH 基团和a是单键,或者X和Y各自为-CH-基团,a为Z或E构型的双键,其中,对于R 1 R 2,R 2,R 3和R 3表示氢,具有1-4个碳原子的脂族基团或-OR- SUP 5,-SR 5或-NR 5 R 6 6基团和R 2 O 2和 R 3彼此独立地表示氢或具有1,2,3,4或5个C原子的烷基,其任选被一个或多个氧代基或R 7 -O-基或R 1和R 2一起形成含有总共4至10个碳原子和0或1个氧原子的脂族环,其中环成分 由R 1和R 2表示的任选被一个或多个氧代基和/或R 7 -O-基团任选取代 和/或具有1至4个C原子的脂族基团和R 3表示氢或具有1,2,3,4或5个C原子的烷基,其任选被一个或多个氧代基团或R O-基或R 2和R 3一起形成含有总共4至10个碳原子的脂族环和0或 1个氧原子,其中由R 2和R 3表示的环成分任选被一个或多个氧代基和/或R 7 -O-基团和/或脂族基团取代 具有1至4个C原子的基团和R 1表示氢,具有1至4个C原子或-OR 5,-SR 5的脂族基团, 其中,对于R 4和R 4 R 4和R 4,R 4,R 4,R 4, 相互独立地表示氢,甲基或乙基,并且其中,对于R 5,R 6和R 7:R 5, R 6和R 7彼此独立地表示氢或脂族基团 具有1至4个C原子的式(I)的羟基苯基吲哚酮的盐,由式(I)的两种或更多种不同羟基苯基偶联物组成或由其组成的混合物,其中X,a,Y,R,R R 1,R 2,R 3,R 4,R 5,R 5,R 5, 在每种情况下,具有上述含义的混合物,包含式(I)的两种或更多种不同的羟基苯基偶联物的盐或由其组成的混合物,其中X, a,Y,R,R 1,R 2,R 3,R 4,R 4, 在每种情况下,R 6,R 6和R 7都具有上述含义,或包含式(I)的羟苯基基二酮或由式 两种或更多种不同的式(I)的羟基苯基偶联物,其中X,a,Y,R,R 1,R 2,R 3, 在每种情况下,R 4,R 5,R 6和R 7都具有上述含义, 羟基苯基烷烃的盐 式(I)的离子或式(I)的不同羟基苯基偶联物的两种或更多种盐,其中X,a,Y,R,R 1,R 2, R 3,R 4,R 5,R 6和R 7, 在每种情况下都具有上述含义,用于改变,掩蔽或减少不愉快品味物质的令人不愉快的风味印象和/或增强甜味物质的甜味和/或芳香物质的甜味气味 引起甜味气味,以及包括式(I)的羟基苯基吲哚酮的制剂和方法。