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1. 发明授权

US09381303B2 Sterility barrier for pen needle and storage container therefor 有权
标题翻译：笔针和储存容器的无菌屏障
公开(公告)号：US09381303B2
公开(公告)日：2016-07-05
申请号：US13205466
申请日：2011-08-08
申请人： Raj Abhijitsinh , Sean Sullivan , Robert Banik , James S. Bates , Cole Constantineau , Ryan Schoonmaker , Michel Bruehwiler , Joshua D. Horvath , Doug Lawrence
发明人： Raj Abhijitsinh , Sean Sullivan , Robert Banik , James S. Bates , Cole Constantineau , Ryan Schoonmaker , Michel Bruehwiler , Joshua D. Horvath , Doug Lawrence
IPC分类号： A61M5/32 , A61M5/24 , A61M5/00 , A61M5/31 , A61M39/26
CPC分类号： A61M5/2455 , A61M5/002 , A61M5/008 , A61M2005/3117 , A61M2005/3118 , A61M2005/312 , A61M2039/267 , Y10T29/49826
摘要： A pen needle includes a hub having a first opening at a first end and a second opening at a second end. A needle is connected to the hub and extends through the first opening at the first end. Access to the needle through the second opening is prevented by a sterility barrier, which has a movable portion that is moved along a longitudinal axis of the needle to provide access to the needle. A storage container includes a housing having a plurality of cavities to receive a plurality of pen needles. A cover is rotatably connected to the housing and is rotated such that an access portion thereof is aligned with one of the cavities, thereby providing access to the pen needle in the cavity.
摘要翻译：笔针包括在第一端具有第一开口和在第二端具有第二开口的毂。针连接到轮毂并且在第一端延伸穿过第一开口。通过第二开口进入针头是通过无菌屏障来防止的，该无菌屏障具有沿着针的纵向轴线移动的可移动部分以提供对针的接近。存储容器包括具有多个腔以容纳多个笔针的壳体。盖可旋转地连接到壳体并且旋转，使得其通路部分与空腔中的一个对准，从而提供对腔中的笔针的接近。

2. 发明授权

US08814831B2 Ballistic microneedle infusion device 有权
标题翻译：弹道微针输液装置
公开(公告)号：US08814831B2
公开(公告)日：2014-08-26
申请号：US13303027
申请日：2011-11-22
申请人： Cole Constantineau , Ryan Schoonmaker , Michel Bruehwiler , Eric Bené
发明人： Cole Constantineau , Ryan Schoonmaker , Michel Bruehwiler , Eric Bené
IPC分类号： A61M5/178 , A61M5/158 , A61M5/142
CPC分类号： A61M5/158 , A61M2005/14264 , A61M2005/1585 , A61M2005/1586 , A61M2205/0216
摘要： An infusion set has a disposable inserter that can insert a needle at a controlled rate of speed to a depth to deliver insulin or other medicament to the upper 3 mm of skin surface, and a skin securing, adhesive layer to secure the skin surface at the insertion site such that the inserter that can insert a needle without a risk of tenting of the skin surface. Position of the inserted needle can be maintained by providing a separated inner and outer hub of the infusion set that can isolate the inserted needle from external forces such that the needle can be maintained at a depth to deliver insulin or other medicament to the upper 3 mm of skin surface during normal use.
摘要翻译：输液器具有一次性插入器，其可以以受控的速度将针头插入到深度以将胰岛素或其它药物输送到皮肤表面的上部3mm，以及皮肤固定粘合剂层，以将皮肤表面固定在插入位置使得插入器能够插入针而没有皮肤表面的隆起的危险。可以通过提供输注组件的分离的内部和外部毂来保持插入的针的位置，该内部和外部毂可以将插入的针与外力隔离，使得针可以保持在深度以将胰岛素或其它药物输送到上部3mm 的皮肤表面正常使用。

3. 发明申请

US20120143136A1 Ballistic Microneedle Infusion Device 有权
标题翻译：弹道微针输液装置
公开(公告)号：US20120143136A1
公开(公告)日：2012-06-07
申请号：US13303027
申请日：2011-11-22
申请人： Cole Constantineau , Ryan Schoonmaker , Michel Bruehwiler , Eric Bené
发明人： Cole Constantineau , Ryan Schoonmaker , Michel Bruehwiler , Eric Bené
IPC分类号： A61B17/34
CPC分类号： A61M5/158 , A61M2005/14264 , A61M2005/1585 , A61M2005/1586 , A61M2205/0216
摘要： An infusion set has a disposable inserter that can insert a needle at a controlled rate of speed to a depth to deliver insulin or other medicament to the upper 3 mm of skin surface, and a skin securing, adhesive layer to secure the skin surface at the insertion site such that the inserter that can insert a needle without a risk of tenting of the skin surface. Position of the inserted needle can be maintained by providing a separated inner and outer hub of the infusion set that can isolate the inserted needle from external forces such that the needle can be maintained at a depth to deliver insulin or other medicament to the upper 3 mm of skin surface during normal use.
摘要翻译：输液器具有一次性插入器，其可以以受控的速度将针头插入到深度以将胰岛素或其它药物输送到皮肤表面的上部3mm，以及皮肤固定粘合剂层，以将皮肤表面固定在插入位置使得插入器能够插入针而没有皮肤表面的隆起的危险。可以通过提供输注组件的分离的内部和外部毂来保持插入的针的位置，该内部和外部毂可以将插入的针与外力隔离，使得针可以保持在深度以将胰岛素或其它药物输送到上部3mm 的皮肤表面正常使用。

4. 发明申请

US20120136300A1 Adjustable Height Needle Infusion Device 有权
标题翻译：可调节高度针头输液装置
公开(公告)号：US20120136300A1
公开(公告)日：2012-05-31
申请号：US13303055
申请日：2011-11-22
申请人： Ryan Schoonmaker , Cole Constantineau , Michel Bruehwiler
发明人： Ryan Schoonmaker , Cole Constantineau , Michel Bruehwiler
IPC分类号： A61M5/46 , A61B17/34
CPC分类号： A61M5/46 , A61M5/158 , A61M5/488 , A61M2005/14252 , A61M2005/14264 , A61M2005/1581 , A61M2005/1585 , A61M2005/1586 , A61M2005/1587 , A61M2005/3289
摘要： An infusion set has a retraction dial that can be removably assembled with the infusion set and access a threaded needle hub contained therein such that the dial can be used to advance or retract a needle hub and an inserted needle to a more precisely controlled insertion depth to deliver insulin or other medicament intradermally (i.e. to the upper 3 mm of skin surface). Position of the inserted needle can be maintained by providing a separated and isolated needle hub, main base and main hub of the infusion set that can isolate the inserted needle from external forces such that the needle can be maintained at a depth to deliver content to the upper 3 mm of skin surface during normal use.
摘要翻译：输液器具有可以与输液器组合并且进入其中包含的螺纹针座的退回拨盘，使得表盘可用于使针座和插入的针前进或缩回以更准确地控制的插入深度皮内递送胰岛素或其他药物（即皮肤表面的上部3mm）。可以通过提供分离和隔离的针座，输液装置的主底座和主轮毂来保持插入的针的位置，其可以将插入的针与外力隔离，使得针可以保持在深度以将内容物输送到正常使用时皮肤表面上方3 mm。

5. 发明申请

US20120136299A1 Slide-Activated Angled Inserter And Cantilevered Ballistic Insertion For Intradermal Drug Infusion 有权
标题翻译：滑动活动角插入器和悬臂弹道插入用于皮内药物输注
公开(公告)号：US20120136299A1
公开(公告)日：2012-05-31
申请号：US13302843
申请日：2011-11-22
申请人： Cole Constantineau , Ryan Schoonmaker , Michel Bruehwiler , Eric Bené
发明人： Cole Constantineau , Ryan Schoonmaker , Michel Bruehwiler , Eric Bené
IPC分类号： A61M5/46 , A61B17/34
CPC分类号： A61M5/158 , A61M2005/1585
摘要： An infusion set has an adhesively secured main hub, and a slidable top cover, needle hub and angled or cantilevered needle that can be used for performing an intradermal needle insertion precisely targeting the upper 3 mm of skin surface, for example, one that substantially duplicates the Mantoux insertion technique, for injecting into the intradermal layers of skin, while maintaining a degree of comfort to the user. By sliding the top cover, the cantilevered needle is loaded and released or the angled needle is slid into an insertion site, while flexible arms and adhesive are used to stretch and/or flatten a skin surface, or otherwise create skin tension, at the insertion site.
摘要翻译：输液器具有粘合固定的主毂，以及可滑动的顶盖，针座和成角度或悬臂针，其可以用于精确地针对皮肤表面上3mm的皮内针插入，例如基本上重复的 Mantoux插入技术，用于将皮肤的皮内层注入，同时保持对使用者的一定程度的舒适度。通过滑动顶盖，悬臂针被装载和释放，或者成角度的针被滑入插入位置，而柔性臂和粘合剂用于在插入时拉伸和/或平坦化皮肤表面或者产生皮肤张力现场。

6. 发明授权

US09950109B2 Slide-activated angled inserter and cantilevered ballistic insertion for intradermal drug infusion 有权
公开(公告)号：US09950109B2
公开(公告)日：2018-04-24
申请号：US13302843
申请日：2011-11-22
申请人： Cole Constantineau , Ryan Schoonmaker , Michel Bruehwiler , Eric Bené
发明人： Cole Constantineau , Ryan Schoonmaker , Michel Bruehwiler , Eric Bené
IPC分类号： A61M5/158
CPC分类号： A61M5/158 , A61M2005/1585
摘要： An infusion set has an adhesively secured main hub, and a slidable top cover, needle hub and angled or cantilevered needle that can be used for performing an intradermal needle insertion precisely targeting the upper 3 mm of skin surface, for example, one that substantially duplicates the Mantoux insertion technique, for injecting into the intradermal layers of skin, while maintaining a degree of comfort to the user. By sliding the top cover, the cantilevered needle is loaded and released or the angled needle is slid into an insertion site, while flexible arms and adhesive are used to stretch and/or flatten a skin surface, or otherwise create skin tension, at the insertion site.

7. 发明授权

US09433757B2 Compact spring inserter for drug delivery infusion set 有权
标题翻译：紧凑弹簧插入器用于药物输注输液器
公开(公告)号：US09433757B2
公开(公告)日：2016-09-06
申请号：US14002210
申请日：2012-02-08
申请人： Cole Constantineau , Ryan Schoonmaker
发明人： Cole Constantineau , Ryan Schoonmaker
IPC分类号： A61M25/06 , A61M5/158
CPC分类号： A61M25/0606 , A61M5/158 , A61M2005/1581 , A61M2005/1585 , A61M2005/1586 , A61M2005/1587
摘要： An infusion set (101) includes a base (111) and an inserter (121) removably connected to the base (111). A catheter (134) is movable from a first catheter position disposed substantially entirely within the inserter (121) to a second catheter position' in which a free end of the catheter (134) is disposed externally of the base (111). An introducer needle (142) is located within the catheter (134) and is movable with the catheter (134) between a first introducer needle position disposed substantially entirely within the inserter (121) and a second introducer needle position in which a free end of the introducer needle (142) is disposed externally of the base (111). A spring member (171) moves the catheter (134) from the first to the second catheter position and the introducer needle (142) from the first to the second introducer needle position to facilitate insertion of the catheter (134). The spring member (171) is disposed substantially entirely within the base (111) when the catheter (134) is in the second catheter position.
摘要翻译：输液器（101）包括可移除地连接到基座（111）的基座（111）和插入件（121）。导管（134）可从基本上完全设置在插入器（121）内的第一导管位置移动至第二导管位置，其中导管（134）的自由端设置在基座（111）的外部。导引针（142）位于导管（134）内并且可以随着导管（134）在基本上完全设置在插入器（121）内的第一引导器针位置和第二引导器针位置之间移动导引针（142）设置在基部（111）的外部。弹簧构件（171）将导管（134）从第一导管位置和导引器针头（142）移动到第一导引器针位置到第二导引器针位置，以便于插入导管（134）。当导管（134）处于第二导管位置时，弹簧构件（171）基本上全部设置在基座（111）内。

8. 发明授权

US09216253B2 Needle dispensing and storing apparatus for medicament delivery device 有权
标题翻译：用于药物输送装置的针头分配和储存装置
公开(公告)号：US09216253B2
公开(公告)日：2015-12-22
申请号：US13204632
申请日：2011-08-05
申请人： Ira Spool , Cole Constantineau , Ryan Schoonmaker , Sean P. Sullivan , Abhijitsinh Raj , Michel Bruehwiler
发明人： Ira Spool , Cole Constantineau , Ryan Schoonmaker , Sean P. Sullivan , Abhijitsinh Raj , Michel Bruehwiler
IPC分类号： B65D83/10 , A61M5/32 , A61M5/00 , A61M5/24
CPC分类号： A61M5/002 , A61M5/003 , A61M5/008 , A61M5/24 , A61M5/3202 , A61M5/3205
摘要： A flip-open multi-pack assembly is provided which can contain a plurality of new pen needles, such as through the provision of a rectangular or tube-shaped shaped, hinged shell housing, wherein new pen needles can be stored in a plurality of user accessible openings each having a sterility barrier formed, for example, by covers that cover the non-patient end of the openings in which the new pen needles are contained. Used pen needles can be returned and stored in openings accessible by rotatably opening the shell housing. One or more of the openings within first and second opposite ends of the housing shell can be provided with a slidable internal holder within the device and are configured to releasably secure the inner shield of the new pen needle, and to then be pulled forward when the new pen needle is removed and lock at a forward position, and thereby create an interior space, accessible from an opposite end when the hinged housing is opened, for a used pen needle to be inserted and stored.
摘要翻译：提供了一种翻转多组件组件，其可以包含多个新的笔针，例如通过设置矩形或管状形状的铰接壳体壳体，其中新的笔针可以存储在多个用户中可接近的开口各自具有例如通过覆盖其中容纳有新的笔针的开口的非患者端的覆盖物形成的无菌屏障。可以将二手笔针返回并储存在可旋转打开壳体外壳的开口中。壳体壳体的第一和第二相对端内的一个或多个开口可以在该装置内设置有可滑动的内部保持器，并且构造成可释放地固定新笔针的内护罩，然后在新的笔针被移除并锁定在前部位置，从而形成内部空间，当打开铰接的外壳时，可以从相对端接近，以便插入和存储用过的笔针。

9. 发明申请

US20120041383A1 Circuitous Band Needle Changing Apparatus 有权
标题翻译：电路带针更换装置
公开(公告)号：US20120041383A1
公开(公告)日：2012-02-16
申请号：US13206405
申请日：2011-08-09
申请人： Michel Bruehwiler , Cole Constantineau , Ryan Schoonmaker , James Bates , Margaret Taylor , Robert Banik
发明人： Michel Bruehwiler , Cole Constantineau , Ryan Schoonmaker , James Bates , Margaret Taylor , Robert Banik
IPC分类号： A61M5/34 , A61M5/31 , A61M5/32
CPC分类号： A61M5/008 , A61M2005/004
摘要： An apparatus is disclosed for storing and changing needles for a medicament delivery device having a medicament container, including a fixed mount for connecting the apparatus with the medicament delivery device, a needle holder displaceable along a circuitous path and connecting a plurality of needles displaceably disposed thereon, and a guide member for guiding displacement of the needle holder, the guide member being disposed about the fixed mount. The apparatus also includes a user interface rotatably disposed about the fixed mount and having at least one internal engaging structure for displacing the needle holder along the circuitous path.
摘要翻译：公开了一种用于存储和更换用于具有药物容器的药物输送装置的针的装置，其包括用于将装置与药物输送装置连接的固定支架，可沿着迂回路径移位并连接可移动地设置在其上的多个针的针保持器以及用于引导针保持器的位移的引导构件，所述引导构件围绕固定座设置。该装置还包括可旋转地设置在固定安装件周围的用户界面，并且具有至少一个内部接合结构，用于沿着迂回路径移动针保持器。

10. 发明申请

US20120041382A1 Pen Injection Device Needle Dispensing and Storing Apparatus 有权
标题翻译：笔注射装置针头分配和储存装置
公开(公告)号：US20120041382A1
公开(公告)日：2012-02-16
申请号：US13205561
申请日：2011-08-08
申请人： David S. Chapin , Daniel M. Stipe , Ryan Schoonmaker , Cole Constantineau , Michel Bruehwiler
发明人： David S. Chapin , Daniel M. Stipe , Ryan Schoonmaker , Cole Constantineau , Michel Bruehwiler
IPC分类号： A61M5/32
CPC分类号： A61M5/3205 , A61M5/002 , A61M5/003 , A61M5/3202 , A61M5/321
摘要： An apparatus is disclosed for storing and dispensing pen needles for an injection device, including a case having dispensing and storage ends for dispensing and storing a plurality of pen needles and a plurality of needle cover units, each pen needle having a patient end and a hub for connection to the injection device, and each needle cover unit having a needle-covering portion for covering a patient end and a hub-covering portion for covering a hub. A needle-covering portion covering the needle of one pen needle is coupled with a hub-covering portion covering a hub of another pen needle. Prior to use, a hub-covering portion covering the hub of a pen needle is exposed to an outside at the dispensing end of the case, and subsequent to use, the pen needle is stored in the storage end of the case.
摘要翻译：公开了一种用于存储和分配用于注射装置的笔针的装置，包括具有用于分配和存储多个笔针的分配和存储端的壳体和多个针盖单元，每个笔针具有患者端和毂用于连接到注射装置，并且每个针头盖单元具有用于覆盖患者端的针覆盖部分和用于覆盖轮毂的轮毂覆盖部分。覆盖一根笔针的针的针覆盖部分与覆盖另一笔针的毂的轮毂覆盖部分联接。在使用之前，覆盖笔针的轮毂的轮毂覆盖部分暴露在壳体的分配端处的外侧，并且在使用之后，笔针被存储在壳体的存储端中。

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