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1. 发明授权

US08900594B2 Oral recombinant Helicobacter pylori vaccine and preparing method thereof 有权
标题翻译：口服重组幽门螺杆菌疫苗及其制备方法
公开(公告)号：US08900594B2
公开(公告)日：2014-12-02
申请号：US12310658
申请日：2007-09-05
申请人： Quanming Zou , Wende Tong , Xuhu Mao , Gang Guo , Dongshui Lu , Chao Wu , Hao Zeng , Yichao Wang , Jun Yang , Weijun Zhang , Kaiyun Liu , Ping Luo
发明人： Quanming Zou , Wende Tong , Xuhu Mao , Gang Guo , Dongshui Lu , Chao Wu , Hao Zeng , Yichao Wang , Jun Yang , Weijun Zhang , Kaiyun Liu , Ping Luo
IPC分类号： A61K39/116 , A61K9/50 , A61K39/00 , A61K39/385 , C12N9/96 , C12N15/00 , C07H21/04 , A61K47/26 , A61K39/02 , C12N9/80 , C07K14/205 , A61K9/19 , C07K14/245
CPC分类号： C12N9/80 , A61K9/19 , A61K39/00 , A61K39/105 , A61K47/26 , A61K2039/542 , A61K2039/55544 , C07K14/205 , C07K14/245 , C07K2319/00 , C07K2319/55
摘要： The invention relates to a recombinant protein used for immunoprophylaxis of human Helicobacter pylori infection and a degradable slow-releasing microsphere-encapsulated oral vaccine preparation prepared from the same, and the preparation method thereof. Said recombinant protein is composed of A2 subunit and B subunit of the LT of enterotoxigenic Escherichia coli and urease B subunit. The vaccine provided in the invention used in human Helicobacter pylori infection is safe and effective and convenient for oral intake.
摘要翻译：本发明涉及用于人幽门螺杆菌感染的免疫预防的重组蛋白质及其制备的可降解的缓释微球包封的口服疫苗制剂及其制备方法。所述重组蛋白由产生肠毒素的大肠杆菌LT和脲酶B亚基的A2亚基和B亚基组成。用于人幽门螺杆菌感染的本发明中提供的疫苗对于口服摄取是安全和有效且方便的。

2. 发明申请

US20110171315A1 Oral recombinant helicobacter pylori vaccine and preparing method thereof 有权
标题翻译：口服重组幽门螺杆菌疫苗及其制备方法
公开(公告)号：US20110171315A1
公开(公告)日：2011-07-14
申请号：US12310658
申请日：2007-09-05
申请人： Quanming Zou , Wende Tong , Xuhu Mao , Gang Guo , Dongshui Lu , Chao Wu , Hao Zeng , Yichao Wang , Jun Yang , Weijun Zhang , Kaiyun Liu , Ping Luo
发明人： Quanming Zou , Wende Tong , Xuhu Mao , Gang Guo , Dongshui Lu , Chao Wu , Hao Zeng , Yichao Wang , Jun Yang , Weijun Zhang , Kaiyun Liu , Ping Luo
IPC分类号： A61K9/14 , C12N9/96 , A61K39/116 , C07H21/00 , C12N15/63 , A61P37/04 , A61P31/04
CPC分类号： C12N9/80 , A61K9/19 , A61K39/00 , A61K39/105 , A61K47/26 , A61K2039/542 , A61K2039/55544 , C07K14/205 , C07K14/245 , C07K2319/00 , C07K2319/55
摘要： The invention relates to a recombinant protein used for immunoprophylaxis of human Helicobacter pylori infection and a degradable slow-releasing microsphere-encapsulated oral vaccine preparation prepared from the same, and the preparation method thereof. Said recombinant protein is composed of A2 subunit and B subunit of the LT of enterotoxigenic Escherichia coli and urease B subunit. The vaccine provided in the invention used in human Helicobacter pylori infection is safe and effective and convenient for oral intake.
摘要翻译：本发明涉及用于人幽门螺杆菌感染的免疫预防的重组蛋白质及其制备的可降解的缓释微球包封的口服疫苗制剂及其制备方法。所述重组蛋白由产生肠毒素的大肠杆菌LT和脲酶B亚基的A2亚基和B亚基组成。用于人幽门螺杆菌感染的本发明中提供的疫苗对于口服摄取是安全和有效且方便的。

3. 发明申请

US20100308556A1 Bicycles driven through driver units 审中-公开
标题翻译：自行车由司机单位驱动
公开(公告)号：US20100308556A1
公开(公告)日：2010-12-09
申请号：US12385226
申请日：2009-04-02
申请人： Qi Nong Jin , Jian Jin , Gang Guo
发明人： Qi Nong Jin , Jian Jin , Gang Guo
IPC分类号： B62M9/04
CPC分类号： B62M23/00 , B62M1/12 , B62M1/32
摘要： This invention relates to the drive technique of bicycles, particularly two-wheel and rear-wheel driven ones. This invention comprises a front-wheel driver unit which moves rectilinearly and directly matches the front-wheel ratchet wheel, to drive the front wheel. It also contains a curvilinear rear-wheel driver unit which moves along a curve and directly matches the rear-wheel ratchet wheel to drive the rear wheel. The two-wheel driven bicycle has a head tube in the front to form a bracket to support the cyclist's shoulders so that the cyclist, while using his or her arms to steer the bicycle and drive the front wheel, does not have to make big effort to support his/her upper body. In the case of the rear-wheel driven bicycle, the identical rear-wheel driver unit used for said two-wheel driven bicycle is used, and the front wheel and the handlebars are just the same as that of a conventional bicycle. Higher drive efficiency can be achieved by using driver units to directly drive cycle wheels, because it converts the maximum effort of the cyclist's arms and/or legs into the rotational moment to drive the bicycle forward. Moreover, the bicycle structure is simple.
摘要翻译：本发明涉及自行车，特别是两轮和后轮驱动的自行车的驱动技术。本发明包括前轮驱动单元，其直线运动并直接匹配前轮棘轮以驱动前轮。它还包含一个曲线后轮驱动单元，沿着曲线移动，直接匹配后轮棘轮驱动后轮。两轮驱动的自行车在前面有一个头管，形成一个支架，用于支撑骑自行车者的肩膀，以便骑自行车的人在用自己的手臂引导自行车并驾驶前轮时，不必付出巨大的努力支持他/她的上半身。在后轮自行车的情况下，使用用于所述两轮自行车的相同的后轮驱动单元，前轮和把手与常规自行车的相同。通过使用驱动单元来直接驱动循环轮可以实现更高的驱动效率，因为它将骑自行车者的手臂和/或腿的最大努力转换为旋转时刻以向前驱动自行车。此外，自行车结构简单。

4. 发明申请

US20060121531A1 Piezoelectric bio-chip for detecting pathogen of mad cow disease and thereon preparation 审中-公开
标题翻译：用于检测疯牛病病原体的压电生物芯片及其制备方法
公开(公告)号：US20060121531A1
公开(公告)日：2006-06-08
申请号：US10523174
申请日：2003-05-22
申请人： Chuanzhong Wei , ZHIHONG Mo , Guiping Ma , Ping Jin , Bingling Li , Xuelong Tian , HAIYAN Tian , Gang Guo
发明人： Chuanzhong Wei , ZHIHONG Mo , Guiping Ma , Ping Jin , Bingling Li , Xuelong Tian , HAIYAN Tian , Gang Guo
IPC分类号： G01N33/53 , C12M1/34 , H01L21/00
CPC分类号： G01N33/6896 , G01N2800/2828
摘要： The present invention relates to the device for animal inspection and quarantine and the preparation method thereof. The present invention is especially applicable to the detection of the pathogen of bovine spongiform encephalopathy (BSE) (also known as “mad cow disease”). The present invention employs a piezoelectric chip, a microelectrode array and a common electrode fixed on the lower side surface and upper side surface of the piezoelectric chip, respectively, and a BSE PrP antibody array to constitute the piezoelectric biochip for the detection of the BSE pathogen. The BSE PrP antibodies are immobilized on the electrodes of the microelectrode array in a format corresponding uniquely to the electrodes of the microelectrode array by adsorbing, bonding, cross-linking, embedding or self-assembly process. The combination of the piezoelectric biochip and a detector constitutes the piezoelectric biochip detection system for the BSE pathogen. When the antibodies react with the corresponding PrPs immunochemically, the information about the PrPs can be detected at real time by measuring the resonant frequency, and the PrPs thus can be analyzed qualitatively and quantitatively. The present invention is applicable to the early, effective and rapid detection of the BSE pathogen.
摘要翻译：本发明涉及动物检疫检疫装置及其制备方法。本发明特别适用于牛海绵状脑病（BSE）病原体的检测（又称“疯牛病”）。本发明分别采用固定在压电芯片的下侧表面和上侧表面上的压电芯片，微电极阵列和公共电极以及BSE PrP抗体阵列，以构成用于检测BSE病原体的压电生物芯片。通过吸附，结合，交联，嵌入或自组装过程，BSE PrP抗体以与微电极阵列的电极唯一相对应的格式固定在微电极阵列的电极上。压电生物芯片和检测器的组合构成了BSE病原体的压电生物芯片检测系统。当抗体与相应的PrPs免疫化学反应时，可以通过测量共振频率实时检测关于PrPs的信息，因此可以定性和定量地分析PrPs。本发明适用于早期有效快速检测BSE病原体。

5. 发明授权

US09528413B2 Synergistic SCR/DOC configurations for lowering diesel emissions 有权
标题翻译：减少柴油排放的协同SCR / DOC配置
公开(公告)号：US09528413B2
公开(公告)日：2016-12-27
申请号：US12847265
申请日：2010-07-30
申请人： Santhoji Rao Katare , Giovanni Cavataio , Douglas Allen Dobson , Gang Guo , Paul M. Laing , William Charles Ruona , Paul Joseph Tennison
发明人： Santhoji Rao Katare , Giovanni Cavataio , Douglas Allen Dobson , Gang Guo , Paul M. Laing , William Charles Ruona , Paul Joseph Tennison
IPC分类号： F01N3/10 , F01N3/20 , F01N13/00
CPC分类号： F01N3/2066 , F01N3/10 , F01N3/106 , F01N13/009 , F01N2610/02 , Y02A50/2325 , Y02T10/24
摘要： A motor-vehicle engine system comprises a first DOC configured to receive exhaust from an engine and an SCR device coupled downstream of the first DOC in a flow direction of the exhaust. The system further comprises a second DOC coupled downstream of the SCR device. The system takes advantage of hydrocarbon sorption in the SCR catalyst that is a function of temperature to enable reduced hydrocarbon emissions via oxidation at the second DOC.
摘要翻译：机动车辆发动机系统包括构造成从发动机接收排气的第一DOC和在排气的流动方向上连接在第一DOC下游的SCR装置。该系统还包括耦合在SCR装置下游的第二DOC。该系统利用SCR催化剂中的烃吸附，其是温度的函数，以通过在第二DOC处的氧化来减少碳氢化合物排放。

6. 发明申请

US20110162347A1 Synergistic SCR / DOC Configurations for Lowering Diesel Emissions 有权
标题翻译：降低柴油排放的协同SCR / DOC配置
公开(公告)号：US20110162347A1
公开(公告)日：2011-07-07
申请号：US12847265
申请日：2010-07-30
申请人： Santhoji Rao Katare , Giovanni Cavataio , Douglas Allen Dobson , Gang Guo , Paul M. Laing , William Charles Ruona , Paul Joseph Tennison
发明人： Santhoji Rao Katare , Giovanni Cavataio , Douglas Allen Dobson , Gang Guo , Paul M. Laing , William Charles Ruona , Paul Joseph Tennison
IPC分类号： F01N3/00 , F01N3/10 , F01N3/035
CPC分类号： F01N3/2066 , F01N3/10 , F01N3/106 , F01N13/009 , F01N2610/02 , Y02A50/2325 , Y02T10/24
摘要： A motor-vehicle engine system comprises a first DOC configured to receive exhaust from an engine and an SCR device coupled downstream of the first DOC in a flow direction of the exhaust. The system further comprises a second DOC coupled downstream of the SCR device. The system takes advantage of hydrocarbon sorption in the SCR catalyst that is a function of temperature to enable reduced hydrocarbon emissions via oxidation at the second DOC.
摘要翻译：机动车辆发动机系统包括构造成从发动机接收排气的第一DOC和在排气的流动方向上连接在第一DOC下游的SCR装置。该系统还包括耦合在SCR装置下游的第二DOC。该系统利用SCR催化剂中的烃吸附，其是温度的函数，以通过在第二DOC处的氧化来减少碳氢化合物排放。

7. 发明申请

US20110023591A1 METHODS AND SYSTEMS FOR DIAGNOSTICS OF AN EMISSION SYSTEM WITH MORE THAN ONE SCR REGION 有权
标题翻译：具有超过一个SCR区域的排放系统的诊断方法和系统
公开(公告)号：US20110023591A1
公开(公告)日：2011-02-03
申请号：US12512640
申请日：2009-07-30
申请人： Douglas Allen Dobson , Giovanni Cavataio , Ed Badillo , Christine Kay Lambert , Gang Guo
发明人： Douglas Allen Dobson , Giovanni Cavataio , Ed Badillo , Christine Kay Lambert , Gang Guo
IPC分类号： G01M15/04
CPC分类号： G01M15/102 , F01N3/106 , F01N3/2006 , F01N3/208 , F01N11/00 , F01N13/0093 , F01N2550/02 , F01N2610/146 , F01N2900/1402 , F01N2900/1602 , F01N2900/1622 , F02D41/0255 , F02D41/029 , F02D41/401 , F02D2200/0802 , Y02A50/2325 , Y02T10/24 , Y02T10/26 , Y02T10/44 , Y02T10/47
摘要： Methods and systems for controlling and/or diagnosing an emission control system of a vehicle having a first SCR region upstream of a second SCR region are provided herein. One exemplary method includes, indicating degradation based on a first SCR region performance during a first condition; and indicating degradation based on a second SCR region performance during a second condition, the first condition different than the second condition. In this way, different levels of degradation among different SCR regions may be used to indicate emissions levels have increased above a threshold value, for example.
摘要翻译：本文提供了用于控制和/或诊断具有第二SCR区域上游的第一SCR区域的车辆的排放控制系统的方法和系统。一种示例性方法包括：在第一状态期间指示基于第一SCR区域性能的劣化; 并且指示在第二状态期间基于第二SCR区域性能的劣化，所述第一条件不同于所述第二条件。以这种方式，例如，可以使用不同SCR区域之间的不同水平的劣化来指示排放水平已经增加到阈值以上。

8. 发明授权

US06810660B2 System for minimizing the impact of poisoning of automotive exhaust aftertreatment systems 有权
标题翻译：用于最小化汽车尾气后处理系统中毒影响的系统
公开(公告)号：US06810660B2
公开(公告)日：2004-11-02
申请号：US10063285
申请日：2002-04-08
申请人： Jeffrey Scott Hepburn , Carolyn Parks Hubbard , Gang Guo , Lifeng Xu , Robert Walter McCabe
发明人： Jeffrey Scott Hepburn , Carolyn Parks Hubbard , Gang Guo , Lifeng Xu , Robert Walter McCabe
IPC分类号： F01N300
CPC分类号： F01N3/035 , B01D53/9495 , F01N3/022 , F01N13/009 , F01N2570/08 , Y10S55/30
摘要： An exhaust aftertreatment system for an internal combustion engine is disclosed which mitigates deleterious poisoning of a catalytic converter or exhaust gas oxygen sensor by phosphorus containing species.
摘要翻译：公开了一种用于内燃机的废气后处理系统，其减轻了含磷物质的催化转化器或废气氧传感器的有害中毒。

9. 发明授权

US08661882B2 Methods and systems for diagnostics of an emission system with more than one SCR region 有权
标题翻译：具有多个SCR区域的排放系统的诊断方法和系统
公开(公告)号：US08661882B2
公开(公告)日：2014-03-04
申请号：US13572478
申请日：2012-08-10
申请人： Douglas Allen Dobson , Giovanni Cavataio , Ed Badillo , Christine Kay Lambert , Gang Guo
发明人： Douglas Allen Dobson , Giovanni Cavataio , Ed Badillo , Christine Kay Lambert , Gang Guo
IPC分类号： G01M15/10
CPC分类号： G01M15/102 , F01N3/106 , F01N3/2006 , F01N3/208 , F01N11/00 , F01N13/0093 , F01N2550/02 , F01N2610/146 , F01N2900/1402 , F01N2900/1602 , F01N2900/1622 , F02D41/0255 , F02D41/029 , F02D41/401 , F02D2200/0802 , Y02A50/2325 , Y02T10/24 , Y02T10/26 , Y02T10/44 , Y02T10/47
摘要： Methods and systems for controlling and/or diagnosing an emission control system of a vehicle having a first SCR region upstream of a second SCR region are provided herein. One exemplary method includes, indicating degradation based on a first SCR region performance during a first condition; and indicating degradation based on a second SCR region performance during a second condition, the first condition different than the second condition. In this way, different levels of degradation among different SCR regions may be used to indicate emissions levels have increased above a threshold value, for example.
摘要翻译：本文提供了用于控制和/或诊断具有第二SCR区域上游的第一SCR区域的车辆的排放控制系统的方法和系统。一种示例性方法包括：在第一状态期间指示基于第一SCR区域性能的劣化; 并且指示在第二状态期间基于第二SCR区域性能的劣化，所述第一条件不同于所述第二条件。以这种方式，例如，可以使用不同SCR区域之间的不同水平的劣化来指示排放水平已经增加到阈值以上。

10. 发明授权

US08516798B2 Methods and systems for control of an emission system with more than one SCR region 有权
标题翻译：用于控制具有多于一个SCR区域的排放系统的方法和系统
公开(公告)号：US08516798B2
公开(公告)日：2013-08-27
申请号：US12512634
申请日：2009-07-30
申请人： Douglas Allen Dobson , Ed Badillo , Gang Guo , James Robert Warner
发明人： Douglas Allen Dobson , Ed Badillo , Gang Guo , James Robert Warner
IPC分类号： F01N3/00
CPC分类号： F01N3/208 , F01N3/035 , F01N3/106 , F01N9/002 , F01N13/009 , F01N13/0093 , F01N13/0097 , F01N2560/021 , F01N2560/14 , F01N2610/02 , F01N2900/1402 , F01N2900/1622 , Y02A50/2325 , Y02T10/24
摘要： Methods and systems for controlling an emission control system of a vehicle having a first SCR region upstream of a second SCR region are provided herein. One exemplary method includes, in a first mode: adjusting an amount of reductant injected upstream of a first SCR region based on a condition of the first SCR region. The method may also include, in a second mode: adjusting the amount of reductant injected upstream of the first SCR region based on a condition of the second SCR region.
摘要翻译：本文提供了用于控制具有第二SCR区域上游的第一SCR区域的车辆的排放控制系统的方法和系统。一种示例性方法包括在第一模式中：基于第一SCR区域的条件来调节在第一SCR区域上游注入的还原剂的量。该方法还可以包括在第二模式中：基于第二SCR区域的条件来调节在第一SCR区域上游注入的还原剂的量。

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