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1. 发明申请

WO2004036502A1 FORMATION OF A 4D (3D+T) IMAGE DATA SET OF A MOVING TUBULAR STRUCTURE 审中-公开
标题翻译：形成运动管状结构的4D（3D + T）图像数据集
公开(公告)号：WO2004036502A1
公开(公告)日：2004-04-29
申请号：PCT/IB2003/004413
申请日：2003-10-08
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N.V. , MOVASSAGHI, Babak , RASCHE, Volker , GRASS, Michael
发明人： MOVASSAGHI, Babak , RASCHE, Volker , GRASS, Michael
IPC分类号： G06T11/00
CPC分类号： G06T11/005 , G06T2211/412
摘要： The invention relates to a method and a device suitable for the formation of a 4D image data set of a three-dimensional tubular structure of an object to be examined, being subject to a periodic motion, from a number of 2D projection images (D) of the tubular structure which have been acquired from different projection directions and in different phases of motion, the periodic motion being represented by a motion signal (E) acquired in parallel with the acquisition of the 2D projection images (D). In order to obtain an as accurate as possible 4D image data set, in accordance with the invention it is proposed to determine 2D center line points (Z) in tubular structure elements (H) in at least two 2D projection images (D) of a first phase of motion, to extract therefrom a first model of 3D center line points (M) and to project these points into further 2D projection images (D) of other phases of motion. The 3D center line points (M) projected therein are automatically registered, so that ultimately the course of the tubular structure element (H) in the individual 2D projection images (D) is obtained, ultimately allowing the reconstruction of 3D images of the tubular structure in different phases of motion. The method in accordance with the invention is preferably used for the formation of a 4D image data set of the coronary vessels of a patient.
摘要翻译：本发明涉及一种适于从多个2D投影图像（D）形成待检查物体的三维管状结构的4D图像数据集的方法和装置，其被进行周期性运动，已经从不同的投影方向和不同运动阶段获取的管状结构，周期运动由与2D投影图像（D）的获取并行获取的运动信号（E）表示。为了获得尽可能准确的4D图像数据集，根据本发明，建议在至少两个2D投影图像（D）中确定管状结构元件（H）中的2D中心线点（Z）第一阶段的运动，从中提取3D中心线点（M）的第一模型，并将这些点投影到其他运动阶段的另外的2D投影图像（D）中。投影在其中的3D中心线点（M）被自动登记，从而最终获得单个2D投影图像（D）中的管状结构元件（H）的过程，最终允许重建管状结构的3D图像在不同的运动阶段。根据本发明的方法优选用于形成患者的冠状血管的4D图像数据集。

2. 发明申请

WO2005027051A1 IMAGING PROCESS AND DEVICE 审中-公开
标题翻译：成像过程和设备
公开(公告)号：WO2005027051A1
公开(公告)日：2005-03-24
申请号：PCT/IB2004/051782
申请日：2004-09-16
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N.V. , GRASS, Michael , RASCHE, Volker
发明人： GRASS, Michael , RASCHE, Volker
IPC分类号： G06T11/00
CPC分类号： G06T11/005 , A61B6/027
摘要： The invention relates to an imaging process with a beam source attached at a first end of an holder device, and with a detector unit attached to a second end of the holder device. The holder device is moved so that the beam source is guided about an examination area along a non-circular trajectory, where the beams emitted by the beam source pass through the examination area. The detector unit acquires measurement values which depend on the intensity of the beams on the far side of the examination area. From these measurement values using a filtered back projection an image of the examination area can be reconstructed, where each measurement value is filtered along a filter line which runs parallel to the tangent of the trajectory at the respective position of the beam source.
摘要翻译：本发明涉及一种成像过程，其中束源连接在保持器装置的第一端，并且检测器单元附接到保持器装置的第二端。保持器装置被移动，使得束源沿着非圆形轨迹围绕检查区域被引导，其中由光束源发射的光束通过检查区域。检测器单元获取取决于在检查区域的远侧的光束的强度的测量值。从使用滤波反投影的这些测量值可以重建检查区域的图像，其中每个测量值沿着平行于光束源的相应位置处的轨迹的切线延伸的滤波器线被滤波。

3. 发明申请

WO2003105017A2 ANALYSIS OF A MULTI-DIMENSIONAL STRUCTURE 审中-公开
标题翻译：多维结构分析
公开(公告)号：WO2003105017A2
公开(公告)日：2003-12-18
申请号：PCT/IB2003/002161
申请日：2003-05-21
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , RASCHE, Volker , MOVASSAGHI, Babak , GRASS, Michael
发明人： RASCHE, Volker , MOVASSAGHI, Babak , GRASS, Michael
IPC分类号： G06F15/60
CPC分类号： G06T7/60 , G06T7/593 , G06T2207/30101 , Y10S128/922
摘要： A method is provided for analysis of a multi-dimensional structure which includes a tubular structure from two-dimensional datasets for respective pre-determined projection directions. A pair of corresponding initial projected centre points of the tubular structure is identified in two respective initial and further two-dimensional datasets.Projected edges of the tubular structure in said initial two-dimensional datasets and in said further two-dimensional dataset near the respective projected centre points are identified. A local size of the tubular structure is derived at the three-dimensional spatial position of the centre point of the tubular structure from said projected edges and the predetermined projection directions.
摘要翻译：提供了一种用于分析多维结构的方法，其包括用于各个预定投影方向的二维数据集的管状结构。管状结构的一对对应的初始投影中心点在两个相应的初始和另外的二维数据集中被识别。所述初始二维数据集中的所述管状结构的边缘以及所述另外的二维数据集中的相应投影确定中心点。在管状结构的中心点从所述投影边缘和预定投影方向的三维空间位置导出管状结构的局部尺寸。

4. 发明申请

WO2012117366A1 VISUALIZATION FOR NAVIGATION GUIDANCE 审中-公开
标题翻译：可视化导航指导
公开(公告)号：WO2012117366A1
公开(公告)日：2012-09-07
申请号：PCT/IB2012/050966
申请日：2012-03-01
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , KING'S COLLEGE LONDON , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , MANZKE, Robert , ETYNGIER, Patrick , CATHIER, Pascal, Yves, François , VILLAIN, Nicolas, François , RASCHE, Volker , RHODE, Kawaldeep, Singh
发明人： MANZKE, Robert , ETYNGIER, Patrick , CATHIER, Pascal, Yves, François , VILLAIN, Nicolas, François , RASCHE, Volker , RHODE, Kawaldeep, Singh
IPC分类号： A61B6/00
CPC分类号： A61B5/066 , A61B6/032 , A61B6/12 , A61B6/488 , A61B6/503 , A61B6/5235 , A61B90/37 , A61B2034/2065 , A61B2090/364 , A61B2090/376
摘要： The present invention relates to visualizing information of an object. In order to provide spatial information and in addition situation specific data to the user while ensuring an effective perceptibility, a method (110) is provided comprising the steps of: a) providing (112) pre-navigation data (114) of a region of interest of an object (22); wherein the pre-navigation data comprises spatial geometrical data (116) and a functional parameter surface (118) in correspondence to the spatial geometrical data; b) acquiring (120) live image data (122) of the region of interest; c) detecting (124) an element (126) in the live image data; d) determining (128) spatial relation (130) of the pre-navigation data and the live image data; e) determining (132)the position (134) of the detected element in the spatial geometrical data, which determining is based on the spatial relation, and computing (136) a predetermined related point of location (138) on the functional parameter surface; f) generating (140) a combination (142) of a simplified surface representation (144) of the region of interest, which simplified surface representation is based on a visualization of the functional parameter surface, and a marker (146) indicating the computed predetermined related point of location; and g) displaying (148) the combination as navigation guidance (150).
摘要翻译：本发明涉及可视化对象的信息。为了在确保有效的可感知性的同时向用户提供空间信息和附加情况特定数据，提供了一种方法（110），包括以下步骤：a）提供（112）前导数据（114）物体（22）的兴趣; 其中所述预导数据包括对应于所述空间几何数据的空间几何数据（116）和功能参数表面（118）; b）获取（120）感兴趣区域的实时图像数据（122）; c）在实况图像数据中检测（124）元素（126）; d）确定前导数据和实况图像数据的（128）空间关系（130）; e）确定（132）在空间几何数据中检测到的元素的位置（134），其基于空间关系进行确定，并且计算（136）功能参数表面上的预定相关位置点（138）; f）产生（140）所述感兴趣区域的简化表面表示（144）的组合（142），所述简化表面表示基于所述功能参数表面的可视化，以及指示所计算的预定相关点位置; 以及g）将所述组合显示（148）作为导航指导（150）。

5. 发明申请

WO2007138526A3 HIERARCHICAL MOTION ESTIMATION 审中-公开
公开(公告)号：WO2007138526A3
公开(公告)日：2007-12-06
申请号：PCT/IB2007/051915
申请日：2007-05-21
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N.V. , SCHÄFER, Dirk , ENGLER, Andreas , MOVASSAGHI, Babak , RASCHE, Volker , GRASS, Michael
发明人： SCHÄFER, Dirk , ENGLER, Andreas , MOVASSAGHI, Babak , RASCHE, Volker , GRASS, Michael
IPC分类号： A61B6/00 , A61B6/03 , G06T3/00 , G06T7/00 , G06T7/20
摘要： In three-dimensional rotational x-ray coronary imaging problems may arise when estimating the motion of small vessels. According to an exemplary embodiment of the present invention, an examination apparatus is provided which is adapted for performing a hierarchical motion estimation by global affine transformation for every heart phase, followed by vessel branch selective affine and non-affine transformations. This may provide for an improved image quality.

6. 发明申请

WO2006003578A1 EXAMINATION APPARATUS FOR PERFUSION STUDIES 审中-公开
标题翻译：检查设备用于灌注研究
公开(公告)号：WO2006003578A1
公开(公告)日：2006-01-12
申请号：PCT/IB2005/052095
申请日：2005-06-24
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , GRASS, Michael , RASCHE, Volker
发明人： GRASS, Michael , RASCHE, Volker
IPC分类号： G06T11/00
CPC分类号： G06T11/005 , A61B6/027 , G06T2211/404 , G06T2211/412 , G06T2211/416
摘要： The invention relates to an examination apparatus and a method for perfusion studies in a patient (1). According to the method, a rotational X-ray device (10) is moved on a closed, preferably non-planar trajectory (T) while continuously generating projections of the patient (1) after the injection of a contrast agent with an injection device (20). The projections are used by a data processing system (30) in a sliding window technique to reconstruct three-dimensional images of the body volume. The resulting sequence of 3D images may be displayed on a monitor (31) to reveal the desired information about the perfusion process.
摘要翻译：本发明涉及一种用于患者（1）中的灌注研究的检查装置和方法。根据该方法，旋转X射线装置（10）在闭合的，优选非平面的轨迹（T）上移动，同时在用注射装置注射造影剂之后连续产生患者（1）的突起 20）。数据处理系统（30）在滑动窗口技术中使用投影来重建身体体积的三维图像。所得到的3D图像序列可以显示在监视器（31）上，以显示关于灌注过程的期望信息。

7. 发明申请

WO2003105017A3 ANALYSIS OF A MULTI-DIMENSIONAL STRUCTURE 审中-公开
公开(公告)号：WO2003105017A3
公开(公告)日：2003-12-18
申请号：PCT/IB2003/002161
申请日：2003-05-21
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , RASCHE, Volker , MOVASSAGHI, Babak , GRASS, Michael
发明人： RASCHE, Volker , MOVASSAGHI, Babak , GRASS, Michael
IPC分类号： G06T7/00
摘要： A method is provided for analysis of a multi-dimensional structure which includes a tubular structure from two-dimensional datasets for respective pre-determined projection directions. A pair of corresponding initial projected centre points of the tubular structure is identified in two respective initial and further two-dimensional datasets.Projected edges of the tubular structure in said initial two-dimensional datasets and in said further two-dimensional dataset near the respective projected centre points are identified. A local size of the tubular structure is derived at the three-dimensional spatial position of the centre point of the tubular structure from said projected edges and the predetermined projection directions.

8. 发明申请

WO2006040715A1 IMAGING SYSTEM FOR THE GENERATION OF HIGH-QUALITY X-RAY PROJECTIONS 审中-公开
标题翻译：用于生成高质量X射线投影的成像系统
公开(公告)号：WO2006040715A1
公开(公告)日：2006-04-20
申请号：PCT/IB2005/053292
申请日：2005-10-06
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N.V. , RASCHE, Volker , PROKSA, Roland
发明人： RASCHE, Volker , PROKSA, Roland
IPC分类号： A61B6/03
CPC分类号： A61B6/466 , A61B6/032 , A61B6/4233 , A61B6/467 , A61B6/469 , A61B6/542
摘要： The invention relates to an imaging system and a method for generating high-quality X-ray projections (24) of a patient (1). The system comprises a rotational X-ray device (10), for example a cone-beam CT-gantry (12), and an associated data processing unit (20). During a medical intervention, low-dose raw projections (22) of the patient (1) are continuously generated from different directions. A volume of interest (23) is then reconstructed from said projections (22), from which high-quality virtual projections (24) can be calculated for a display on a monitor (25). The number and direction of said virtual projections (24) can be arbitrarily chosen by the user.
摘要翻译：本发明涉及一种用于产生患者（1）的高质量X射线投影（24）的成像系统和方法。该系统包括旋转X射线装置（10），例如锥形束CT机架（12）和相关联的数据处理单元（20）。在医疗干预期间，从不同方向连续地生成患者（1）的低剂量原始投影（22）。然后从所述投影（22）重建感兴趣的体积（23），从而可以计算高质量虚拟投影（24）以在监视器（25）上显示。所述虚拟投影（24）的数量和方向可以由用户任意选择。

9. 发明申请

WO2006003576A3 IMAGE PROCESSING SYSTEM, PARTICULARLY FOR IMAGES OF IMPLANTS 审中-公开
公开(公告)号：WO2006003576A3
公开(公告)日：2006-01-12
申请号：PCT/IB2005/052093
申请日：2005-06-24
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , RASCHE, Volker
发明人： RASCHE, Volker
IPC分类号： G06T17/40
摘要： The invention relates to an image processing system that is adapted to generate a three-dimensional image (32) from projections (P, 31) of a body volume which may for example be generated by a rotational X-ray system (10). The image processing system is further adapted to display on a monitor (30) simultaneously at least one of the original projections (31) and the generated 3D-image (32) together with a superimposed representation of a target region like an implantable stent. The user may then change the dimensions and the shape of the target region in any of the displayed images (31, 32) and watch the results in all images (31, 32). As the original projections (31) are free of errors generated by the reconstruction and visualization of the 3D-image (32), their consideration yields an improved geometrical accuracy.

10. 发明申请

WO2004068412A1 METHOD FOR THE RECONSTRUCTION OF THREE-DIMENSIONAL OBJECTS 审中-公开
标题翻译：重建三维物体的方法
公开(公告)号：WO2004068412A1
公开(公告)日：2004-08-12
申请号：PCT/IB2004/000185
申请日：2004-01-23
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N.V. , WEESE, Jürgen , RASCHE, Volker , YOUNG, Stewart , MOVASSAGHI, Babak
发明人： WEESE, Jürgen , RASCHE, Volker , YOUNG, Stewart , MOVASSAGHI, Babak
IPC分类号： G06T7/00
CPC分类号： G06T7/11 , G06T7/55 , G06T2207/10121 , G06T2207/20156 , G06T2207/30101
摘要： The invention relates to a method for the computer-aided reconstruction of a three-dimensional anatomical object (3) from diagnostic image data. First of all, a diagnostic image data set of the object (3) is acquired. Then a seed point (5) is set, starting from which the object is reconstructed within a reconstruction volume (4). Thereafter, an adjacent point of the reconstruction volume (4) likewise belonging to the object (3) is located in accordance with a propagation criterion, which is calculated by means of a mathematical analysis of local areas (6, 7), assigned to the point concerned, of the image data set. Reconstruction of the three-dimensional structure of the object (3) is then performed within the reconstruction volume (4) by multiple repetition of this method step and propagation along the located adjacent points. To apply such a reconstruction method to image data obtained by means of rotational X-ray imaging, wherein a plurality of two-dimensional projection images (1, 2) are recorded from different projection directions, the invention proposes that the propagation criterion be calculated by subjecting the local image areas (6, 7) of the two-dimensional projection images (1, 2) in each case individually to the mathematical analysis.
摘要翻译：本发明涉及一种用于从诊断图像数据计算机辅助重构三维解剖体（3）的方法。首先，获取对象（3）的诊断图像数据集。然后设置种子点（5），从重建体积（4）中重建对象开始。此后，同样属于对象（3）的重构体积（4）的相邻点根据通过局部区域（6,7）的数学分析计算的传播标准来定位，分配给关注图像数据集。然后通过该方法步骤的多次重复和沿着定位的相邻点的传播，在重构体积（4）内重构物体（3）的三维结构。为了将这种重建方法应用于通过旋转X射线成像获得的图像数据，其中从不同的投影方向记录多个二维投影图像（1,2），本发明提出传播准则由在每种情况下对二维投影图像（1,2）的局部图像区域（6,7）进行数学分析。

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