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1. 发明授权

US06671549B2 Pacemaker utilizing QT dynamics to diagnose heart failure 有权
标题翻译：起搏器利用QT动力学诊断心力衰竭
公开(公告)号：US06671549B2
公开(公告)日：2003-12-30
申请号：US09987796
申请日：2001-11-16
申请人： Peter M. Van Dam , Diederick M. Keizer , Mattias Rouw Rouw , Jos P. A. Smit
发明人： Peter M. Van Dam , Diederick M. Keizer , Mattias Rouw Rouw , Jos P. A. Smit
IPC分类号： A61N137
CPC分类号： A61B5/02405 , A61B5/0452 , A61B5/11 , A61B5/7285 , A61N1/365 , A61N1/3684
摘要： The invention presents a medical device system and method for determining the degree of heart failure of a patient, utilizing information representative of dynamic variations in patient QT, or segments of QT, over time. The dynamic variations in QT that are measured relate to characteristics of the variation of QT with rate when rate is increasing and when it is decreasing. The dynamic variations include QT dynamic range, QT hysteresis, and QT directrix, each providing important information relating to the patient's variation of QT with heart rate, or QT(RR). QT and dynamic variations of QT can be measured in both left and right ventricles, and taken over the patient's normal rate range. The dynamic data is measured and stored periodically and compared with historical data to determine progression toward heart failure. In another embodiment, the QRST signals are divided into segments, namely QRS width; ST segment; and T wave width, and variations of these segments are analyzed to provide additional information indicative of the patient's heart condition. Preferably the system utilizes a microprocessor programmed to carry out an algorithm that weighs detected variations in QT, QT segments and/or QT dynamic parameters with time to track cardiac changes.
摘要翻译：本发明提出了一种用于确定患者心力衰竭程度的医疗装置系统和方法，利用代表患者QT中的动态变化的信息或QT的片段随时间推移。测量的QT的动态变化与QT的变化特征有关，其速率随着速率的增加而逐渐减小。动态变化包括QT动态范围，QT滞后和QT指令，每个提供与患者QT与心率变化或QT（RR）相关的重要信息。 QT和QT的动态变化可以在左心室和右心室中测量，并且超过患者的正常速率范围。定期测量和存储动态数据，并与历史数据进行比较，以确定进展为心力衰竭。在另一个实施例中，QRST信号被分成段，即QRS宽度; ST段; 和T波宽度，并且分析这些片段的变化以提供指示患者心脏状况的附加信息。优选地，该系统利用被编程的微处理器来执行一种算法，该算法可以随时间跟踪心脏变化来重新检测QT，QT段和/或QT动态参数中的变化。

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