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1. 发明申请

WO2019097338A1 MULTI-SPOT LASER PROBE WITH ILLUMINATION FEATURES 审中-公开
公开(公告)号：WO2019097338A1
公开(公告)日：2019-05-23
申请号：PCT/IB2018/058551
申请日：2018-10-31
申请人： NOVARTIS AG
发明人： MIRSEPASSI, Alireza , DIAO, Chenguang , FARLEY, Mark Harrison , SMITH, Ronald T. , HORN, Jochen
IPC分类号： A61F9/008
CPC分类号： A61B90/30 , A61B2018/208 , A61B2018/2211 , A61B2090/306 , A61F9/008 , A61F9/00821 , A61F9/00823 , A61F2009/00863 , G02B6/0006 , G02B6/0008
摘要： Multi-fiber laser probes utilize relative motion of fibers and other laser probe elements to preserve small-gauge compatibility while providing for multi-spot beam deliver, or to provide for the selectively delivery of single-spot or multi-spot beam patterns. An example probe includes fibers having distal ends that are movable as a group onto a distal ramp element affixed to a distal end of a cannula, so that the distal ends of the fibers can be moved between a retracted position, in which the distal ends of the fibers are within the cannula or ramp element, and an extended position, in which distal ends of the fibers are guided by grooves or channels of the ramp so as to extend at least partially through external openings in the distal end of the laser probe and so as to be pointed angularly away from a longitudinal axis of the cannula.

2. 发明申请

WO2018092002A1 MEDICAL INSTRUMENT WITH AN INTEGRATED OPTICAL FIBER 审中-公开
公开(公告)号：WO2018092002A1
公开(公告)日：2018-05-24
申请号：PCT/IB2017/056965
申请日：2017-11-07
申请人： NOVARTIS AG
发明人： MIRSEPASSI, Alireza , WHEATLEY, Barry L. , SMITH, Ronald T. , PAPAC, Michael J. , DIAO, Chenguang , PARTO, Kambiz , MCDONELL, Brian William , FARLEY, Mark Harrison
IPC分类号： A61F9/007 , A61B18/00 , A61B90/30
摘要： Provided herein is an illuminated microsurgical instrument system and an illuminated microsurgical instrument. In one implementation, the system includes a microsurgical instrument having a distally projecting tubular member arranged to perform a medical procedure at an interventional site. The tubular member has a distal tip and an outer surface, the outer surface having a flat surface formed therein. The instrument includes a sheath member surrounding a portion of the tubular member and extending toward the distal tip of the tubular member and an optical fiber extending along a length of the flat surface between the tubular member and the sheath member. The instrument may further include a slack chamber, collar structure, and fiber guard member to support and guide the optical fiber to the distal tip.

3. 发明申请

WO2017103847A1 METHOD OF MAKING DIVERGING-LIGHT FIBER OPTICS ILLUMINATION DELIVERY SYSTEM 审中-公开
标题翻译：制造发散光纤光学照明传输系统的方法
公开(公告)号：WO2017103847A1
公开(公告)日：2017-06-22
申请号：PCT/IB2016/057670
申请日：2016-12-15
申请人： NOVARTIS AG
发明人： MIRSEPASSI, Alireza , SMITH, Ronald T. , PAPAC, Michael J. , DIAO, Chenguang
IPC分类号： F21V8/00 , A61B1/07 , A61F9/007 , G02B6/24 , G02B6/26 , A61B90/00
CPC分类号： A61B90/30 , A61B1/00096 , A61B1/0011 , A61B1/07 , A61B17/00 , A61B90/36 , A61B2017/00526 , A61B2090/306 , A61F9/007 , G02B5/021 , G02B5/0242 , G02B5/0247 , G02B6/0008 , G02B6/241 , G02B6/262
摘要： A process of making a diverging-light fiber optics illumination delivery system includes providing a micro-post comprising a glass-ceramic light-scattering element that includes at least one of a ceramic, a glass ceramic, an immiscible glass, a porous glass, opal glass, amorphous glass, an aerated glass, and a nanostructured glass; and fusion-splicing the glass-ceramic micro-post to the optical fiber by pulling an arc between electrodes across a gap formed by the optical fiber and the glass-ceramic micro-post; maintaining the arc for a time sufficiently long to make facing surfaces of the optical fiber and the micro-post one of malleable and molten; and pushing and thereby fusing together the facing surfaces of the optical fiber and the micro-post. Some embodiments can include fusing the glass-ceramic micro-post to the optical fiber by applying a laser beam to heat up at least one of the facing surfaces of the optical fiber and the glass-ceramic micro-post.
摘要翻译：制造发散光纤光学照明输送系统的方法包括提供包括玻璃陶瓷光散射元件的微柱，所述微柱包括陶瓷，玻璃陶瓷，玻璃陶瓷，不混溶玻璃，多孔玻璃，蛋白石玻璃，非晶玻璃，充气玻璃和纳米结构玻璃; 通过在由光纤和玻璃陶瓷微柱形成的间隙上的电极之间牵引电弧，将玻璃 - 陶瓷微柱与光纤熔接; 将电弧保持足够长的时间以使光纤和微柱的相对表面具有延展性和熔融性; 并推动并由此将光纤和微柱的相对表面熔合在一起。一些实施例可以包括通过施加激光束来加热光纤和玻璃陶瓷微柱的至少一个相对表面来将玻璃陶瓷微柱与光纤熔合。

4. 发明申请

WO2017103692A1 OPHTHALMIC ILLUMINATION SYSTEMS, DEVICES, AND METHODS 审中-公开
标题翻译：眼科照明系统，装置和方法
公开(公告)号：WO2017103692A1
公开(公告)日：2017-06-22
申请号：PCT/IB2016/055085
申请日：2016-08-25
申请人： NOVARTIS AG
发明人： SMITH, Ronald T. , MIRSEPASSI, Alireza
IPC分类号： A61B3/00 , A61B90/30 , G02B6/24
CPC分类号： A61B90/30 , A61B3/0008 , A61B3/10 , A61B2090/306 , A61F9/007 , G02B6/24 , G02B19/0028 , G02B19/0047 , G02B27/141
摘要： Systems, apparatuses, and methods of and for an ophthalmic illumination system are disclosed. In an exemplary implementation, an ophthalmic illumination system (220) includes a collimator (226) having at least one lens. The system includes a first mirror (224a) arranged to reflect light towards the collimator. The first mirror is configured for use with a first light source that emits a first light beam having a first parameter, such as a first numerical aperture. The system includes a second mirror (224b) arranged to reflect light towards the collimator (226). The second mirror (224b) is configured for use with a second light source emitting a second light beam having a second parameter that is different than the first parameter. The second mirror is shaped and arranged to cause a reflected portion of the second light beam to have the first parameter. The first mirror and the first light source, and the second mirror and the second light source, are separately usable with the collimator.
摘要翻译：公开了用于和用于眼科照明系统的系统，设备和方法。在示例性实现中，眼科照明系统（220）包括具有至少一个透镜的准直器（226）。该系统包括布置成朝向准直器反射光的第一反射镜（224a）。第一镜被配置为与发射具有第一参数（例如第一数值孔径）的第一光束的第一光源一起使用。该系统包括布置成朝向准直器（226）反射光的第二反射镜（224b）。第二反射镜（224b）被配置为与发射具有不同于第一参数的第二参数的第二光束的第二光源一起使用。第二反射镜被成形并布置成使第二光束的反射部分具有第一参数。第一反射镜和第一光源以及第二反射镜和第二光源可与准直器分开使用。

5. 发明申请

WO2017103796A1 DIVERGING LIGHT FROM FIBER OPTICS ILLUMINATION DELIVERY SYSTEM 审中-公开
标题翻译：纤维光学照明传递系统中的散射光
公开(公告)号：WO2017103796A1
公开(公告)日：2017-06-22
申请号：PCT/IB2016/057591
申请日：2016-12-13
申请人： NOVARTIS AG
发明人： MIRSEPASSI, Alireza , SMITH, Ronald T. , PAPAC, Michael J. , DIAO, Chenguang
IPC分类号： F21V8/00 , A61B1/07 , A61F9/007 , G02B6/24 , G02B6/26 , A61B90/00
CPC分类号： G02B6/0008 , A61B1/07 , A61B90/36 , A61F9/00736 , A61F9/008 , G02B5/021 , G02B5/0242 , G02B5/0247 , G02B6/241 , G02B6/262
摘要： An illumination fiber optics is provided that includes an optical fiber, configured to receive illumination light at a proximal end from a light source; and a light-scattering element, at a distal end of the optical fiber, configured to receive the illumination light from the optical fiber at a proximal end and to emit the illumination light at a distal end in a wide angle. The illumination fiber optics can be prepared by providing an optical fiber, configured to receive illumination light at a proximal end from a light source; and creating a light-scattering element at a distal end of the optical fiber, configured to receive the illumination light from the optical fiber at a proximal end and to emit the illumination light at a distal end in a wide angle.
摘要翻译：提供了一种照明光纤，其包括：光纤，被配置为在光源的近端处接收照明光; 以及在光纤的远端处的光散射元件，所述光散射元件被构造成在近端处接收来自光纤的照明光并且以广角在远端处发射照明光。照明光纤可以通过提供光纤来制备，该光纤被配置为在光源的近端处接收照明光; 以及在所述光纤的远端处形成光散射元件，所述光散射元件被构造成在近端处接收来自所述光纤的所述照明光并且在远端处以广角发射所述照明光。

6. 发明申请

WO2016099956A1 BSS-ONLY MULTI-SPOT LASER PROBE 审中-公开
标题翻译： BSS只有多点激光探头
公开(公告)号：WO2016099956A1
公开(公告)日：2016-06-23
申请号：PCT/US2015/063958
申请日：2015-12-04
申请人： NOVARTIS AG , SMITH, Ronald T.
发明人： SMITH, Ronald T.
IPC分类号： A61F9/008 , A61B18/22 , G02B6/28 , A61B18/20
CPC分类号： A61F9/008 , A61B2018/2005 , A61F9/00825 , A61F9/0084 , A61F2009/00848 , A61F2009/00851 , A61F2009/0087 , A61F2009/00872 , A61F2009/00889 , A61F2009/00897 , G02B6/00 , G02B7/027 , G02B23/06
摘要： An optical surgical probe includes a cylindrical cannula; a light guide partially within the cannula to receive a light beam from a light source through a proximal end, to guide the light beam to a distal end of the light guide, and to emit the light beam through the distal end of the light guide; a multi-spot generator at a distal end of the cannula that includes an optical element with a proximal surface to receive the emitted light beam, and a focusing lens, positioned inside the optical element to focus the received light beam into a focused beam, wherein the optical element has a faceted distal surface to split the focused beam into multiple distally emitted beam-components when the optical surgical probe is operated in a fluid with an index of refraction of 1.30-1.40, and to confine the focused beam in the optical surgical probe when the optical surgical probe is operated in air.
摘要翻译：光学手术探针包括圆柱形插管; 部分地在套管内的光导，用于接收来自光源的光束通过近端，将光束引导到光导的远端，并且通过光导的远端发射光束; 在套管的远端处的多点发生器，其包括具有接近发射光束的近端表面的光学元件和位于光学元件内的聚焦透镜，以将所接收的光束聚焦到聚焦光束中，其中当光学手术探针在折射率为1.30-1.40的流体中操作时，光学元件具有刻面的远侧表面，以将聚焦的光束分成多个远端发射的光束分量，并且将聚焦光束限制在光学手术当光学手术探针在空气中操作时探测。

7. 发明申请

WO2019116287A1 THERMALLY ROBUST LASER PROBE ASSEMBLY 审中-公开
公开(公告)号：WO2019116287A1
公开(公告)日：2019-06-20
申请号：PCT/IB2018/059981
申请日：2018-12-12
申请人： NOVARTIS AG
发明人： COOK, Christopher , DIAO, Chenguang , FARLEY, Mark Harrison , MIRSEPASSI, Alireza , PARTO, Kambiz , SMITH, Ronald T.
IPC分类号： A61F9/008 , A61B18/20 , A61B18/24 , A61B18/22 , G02B6/02
摘要： Certain aspects of the present disclosure provide a thermally robust laser probe assembly comprising a cannula, wherein one or more optical fibers extend at least partially through the cannula for transmitting laser light from a laser source to a target location. The probe assembly further comprises a lens housed in the cannula and a protective component press-fitted to the distal end of the cannula, wherein the lens is positioned between the one or more optical fibers and the protective component.

8. 发明申请

WO2019116281A1 MULTIPLE-INPUT-COUPLED ILLUMINATED MULTI-SPOT LASER PROBE 审中-公开
公开(公告)号：WO2019116281A1
公开(公告)日：2019-06-20
申请号：PCT/IB2018/059975
申请日：2018-12-12
申请人： NOVARTIS AG
发明人： SMITH, Ronald T. , MIRSEPASSI, Alireza , FARLEY, Mark Harrison , BACHER, Gerald David
IPC分类号： A61F9/008 , A61B18/20
摘要： Systems and methods for creating multi-spot laser light beams, multiplexing an illumination light and the multi-spot laser light beams, delivering the multiplexed light to a surgical handpiece via a multi-core optical fiber cable, and delivering the multiplexed light onto patient anatomy.

9. 发明申请

WO2018158653A1 MULTI-FIBER MULTI-SPOT LASER PROBE WITH ARTICULATING BEAM SEPARATION 审中-公开
公开(公告)号：WO2018158653A1
公开(公告)日：2018-09-07
申请号：PCT/IB2018/051038
申请日：2018-02-20
申请人： NOVARTIS AG
发明人： DIAO, Chenguang , FARLEY, Mark Harrison , MIRSEPASSI, Alireza , SMITH, Ronald T.
IPC分类号： A61B18/22 , A61F9/008 , F21V8/00 , G02B6/04 , G02B6/26 , G02B6/36
摘要： Multi-fiber laser probes utilize relative motion of fibers and other laser probe elements to preserve small-gauge compatibility while providing for multi-spot beam deliver, or to provide for the selectively delivery of single-spot or multi-spot beam patterns. An example probe includes fibers having distal ends that are movable as a group onto a distal ramp element affixed to a distal end of a cannula, so that the distal ends of the fibers can be moved between a retracted position, in which the distal ends of the fibers are within the cannula or ramp element, and an extended position, in which distal ends of the fibers are guided by grooves or channels of the ramp so as to extend at least partially through external openings in the distal end of the laser probe and so as to be pointed angularly away from a longitudinal axis of the cannula.

10. 发明申请

WO2018158652A1 MULTI-FIBER MULTI-SPOT LASER PROBE WITH SIMPLIFIED TIP CONSTRUCTION 审中-公开
公开(公告)号：WO2018158652A1
公开(公告)日：2018-09-07
申请号：PCT/IB2018/051036
申请日：2018-02-20
申请人： NOVARTIS AG
发明人： DIAO, Chenguang , FARLEY, Mark Harrison , MIRSEPASSI, Alireza , PARTO, Kambiz , SMITH, Ronald T.
IPC分类号： A61F9/008 , A61B18/22 , G02B6/04 , G02B6/24
摘要： An example multi-fiber, multi-spot laser probe comprises a plurality of fibers extending from a proximal end of the laser probe to at least near a distal end of the laser probe, where the proximal end of the laser probe is configured to be coupled to a laser source via an adapter interface, and a cannula having a distal end and surrounding the plurality of fibers along at least a portion of the laser probe at or near the distal end of the laser probe, where a distal end of each of the plurality of fibers is angle-polished so that the distal end of each fiber is angled relative to a longitudinal axis of the cannula and relative to a plane perpendicular to the longitudinal axis of the cannula. Additional embodiments employ lensed fibers, a distal window, ball lens, lens array, or faceted wedge.

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