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1. 发明授权

US08077940B2 Method for reconstructing a three-dimensional target volume in realtime and displaying it 有权
标题翻译：实时重建三维目标体积并进行显示的方法
公开(公告)号：US08077940B2
公开(公告)日：2011-12-13
申请号：US11725830
申请日：2007-03-20
申请人： Matthias John , Norbert Rahn
发明人： Matthias John , Norbert Rahn
IPC分类号： G06K9/00
CPC分类号： A61B8/12 , A61B5/0066 , A61B5/0456 , A61B8/543 , G06T11/005 , G06T2211/428
摘要： The invention relates to a method for reconstructing a three-dimensional target volume, particularly within the human body, in realtime and displaying it, with a three-dimensional reconstruction volume being determined from a basic set comprising a minimum number of two-dimensional images obtained from an image recording device located within the target volume, wherein, when a new image is included in the basic set, locally limited updating at least of the reconstruction volume's partial areas covered by the new image will under a predefined condition be performed and the updated reconstruction volume will be displayed.
摘要翻译：本发明涉及一种用于重建三维目标体积，特别是在人体内实时地显示三维目标体积的方法，并且显示三维目标体积，其中三维重建体积是从包括最小数目的二维图像获得的基本集合确定的从位于所述目标体积内的图像记录装置，其中，当在所述基本组中包括新图像时，在执行所述新图像所覆盖的至少所述重建体积的部分区域内的局部限制更新将被执行，并且所述更新重建体积将被显示。

2. 发明申请

US20110019892A1 METHOD AND APPARATUS FOR VISUALLY SUPPORTING AN ELECTROPHYSIOLOGICAL CATHETER APPLICATION 审中-公开
标题翻译：用于视觉支持电生理导管应用的方法和装置
公开(公告)号：US20110019892A1
公开(公告)日：2011-01-27
申请号：US12840361
申请日：2010-07-21
申请人： Norbert Rahn , Dietrich Till
发明人： Norbert Rahn , Dietrich Till
IPC分类号： G06K9/00
CPC分类号： A61B6/12 , A61B6/4441 , A61B6/466 , A61B6/503 , A61B6/504 , A61B8/0891 , A61B18/1492 , A61B2090/065 , G06T19/00 , G06T2210/41
摘要： A method for visually supporting an electrophysiological catheter application is provided. An electroanatomical 3D mapping data of a region of interest in the heart is visualized. A 3D image data of the region of interest is captured before the catheter application. A 3D surface profile of objects in the region of interest is extracted from the 3D image data by segmentation. The electroanatomical 3D mapping data and 3D image data forming at least the 3D surface profile is assigned by registration and visualized superimposed on one another. Characteristic parameters are measured for catheter guidance during the catheter application. The characteristic parameters are compared with at least one predefined threshold value and regulation data for catheter guidance is generated as a function of the comparison result. The regulation data is integrally displayed and represented in the superimposed visualization.
摘要翻译：提供了用于视觉上支持电生理学导管应用的方法。可视化心脏中感兴趣区域的电解剖3D绘图数据。在导管应用之前捕获感兴趣区域的3D图像数据。通过分割从3D图像数据中提取感兴趣区域中的对象的3D表面轮廓。形成至少3D表面轮廓的电解剖3D图形数据和3D图像数据通过配准分配并且可视化地彼此叠加。在导管应用期间测量导管引导的特征参数。将特征参数与至少一个预定义的阈值进行比较，并且作为比较结果的函数产生用于导管引导的调节数据。调整数据在叠加的可视化中一体地显示和表示。

3. 发明授权

US07792593B2 Method and system for patient-specific production of a cardiac electrode 有权
标题翻译：用于患者特异性生产心脏电极的方法和系统
公开(公告)号：US07792593B2
公开(公告)日：2010-09-07
申请号：US11600976
申请日：2006-11-17
申请人： Norbert Rahn , Jan Boese
发明人： Norbert Rahn , Jan Boese
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N2001/0585
摘要： In a method and system for patient-specific production of a cardiac electrode lead, a 3D representation of the coronary sinus vessel tree is segmented to indicate the interior surface thereof and a representative line from an opening of the coronary sinus vessel tree to an implantation site for the electrode lead, and a computerized model of the electrode is generated that includes deformation properties of the mechanical structure of the electrode lead. A computerized virtual implantation of the electrode through the 3D representation of the coronary sinus vessel tree is implemented using the model and the internal surface and the representative line from which determination is made as to whether an electrode conforming to the model can be guided to and implanted at the implantation site in a medically acceptable manner, or whether modification of the electrode lead is necessary.
摘要翻译：在用于患者特异性生产心脏电极引线的方法和系统中，冠状窦血管树的3D表示被分割以指示其内表面和从冠状窦血管树的开口到植入部位的代表性线并且产生电极的计算机化模型，其包括电极引线的机械结构的变形特性。通过冠状窦血管树的3D表示的电极的电脑化虚拟植入是使用模型和内表面以及代表性线来实现的，其中确定是否能够引导符合模型的电极和植入在植入部位以医学上可接受的方式，或者是否需要修改电极引线。

4. 发明授权

US07761135B2 Method and device for correction motion in imaging during a medical intervention 有权
标题翻译：用于在医疗干预期间成像中校正运动的方法和装置
公开(公告)号：US07761135B2
公开(公告)日：2010-07-20
申请号：US11636953
申请日：2006-12-11
申请人： Marcus Pfister , Norbert Rahn
发明人： Marcus Pfister , Norbert Rahn
IPC分类号： A61B5/05
CPC分类号： A61B6/504 , A61B6/12 , G06T5/50 , G06T7/33 , G06T7/38 , G06T2207/10072 , G06T2207/10121 , G06T2207/20221 , G06T2207/30101
摘要： The present invention relates to a method and a device for correcting motion in imaging during a medical intervention, by which method a 3D tomographic image of a target area for the intervention is first recorded while there are one or more medical instruments in the target area that will remain there during the intervention. During the intervention 2D fluoroscopic images of the target area are recorded and registered with the 3D image. The registration is therein adjusted for each 2D fluoroscopic image in realtime based in each case on the one or more instruments. The 2D fluoroscopic images are then in each case visualized with representations, concurring in terms of perspective, of the 3D image. Virtually error-free overlaying of the 3D image with in each case one 2D fluoroscopic image can be implemented using the present method and associated device.
摘要翻译：本发明涉及一种用于在医疗介入期间校正成像中的运动的方法和装置，通过该方法首先记录用于干预的目标区域的3D断层图像，同时目标区域中存在一个或多个医疗器械将在干预期间留在那里。在干预期间，记录2D目标区域的二维透视图像并将其与3D图像一起登记。在每个情况下，在一个或多个仪器上实时地对每个2D透视图像进行配准。然后，2D透视图像在每种情况下可视化，并以透视方式同意3D图像。在每种情况下，3D图像的几乎无误差的重叠可以使用本方法和相关联的装置来实现一个2D透视图像。

5. 发明申请

US20100104164A1 Method and device for obtaining a volume data set of a mobile tissue or organ of a patient 有权
标题翻译：用于获得患者的移动组织或器官的体积数据集的方法和装置
公开(公告)号：US20100104164A1
公开(公告)日：2010-04-29
申请号：US12518123
申请日：2008-04-04
申请人： Meir Bartal , Jan Boese , Assaf Govari , Matthias John , Assaf Preiss , Norbert Rahn
发明人： Meir Bartal , Jan Boese , Assaf Govari , Matthias John , Assaf Preiss , Norbert Rahn
IPC分类号： G06K9/62
CPC分类号： A61B6/4441 , A61B5/1127 , A61B6/503 , A61B6/583
摘要： A method and a device for obtaining a volume data set of a mobile tissue or organ of a patient by a C-arm X-ray device are provided. An electromagnetic sensor of a position detection system is arranged indirectly on the tissue or organ. The X-ray device obtains a plurality of X-ray projections from the tissue or organ from various projection directions. A first method consists of reconstructing a volume data set from the X-ray projections, in which the electromagnetic sensor adopts a position characterizing a displacement phase of the tissue or organ. A second method consists of reconstructing a volume data set from the X-ray projections captured when the electromagnetic sensor was located in a position characterizing a displacement phase of the tissue or organ. A third method does not capture an X-ray projection for the reconstruction if the electromagnetic sensor is located in a position characterizing a displacement phase.
摘要翻译：提供了一种用于通过C臂X射线装置获得患者的移动组织或器官的体积数据集的方法和装置。位置检测系统的电磁传感器间接地布置在组织或器官上。 X射线装置从各种投影方向从组织或器官获得多个X射线投射。第一种方法包括从X射线投影重建体数据集，其中电磁传感器采用表征组织或器官位移阶段的位置。第二种方法包括当电磁传感器位于表征组织或器官的位移阶段的位置时，从所捕获的X射线投影中重建体数据集。如果电磁传感器位于表征位移相位置的位置，则第三种方法不能捕获用于重建的X射线投影。

6. 发明授权

US07578787B2 Catheter device 有权
标题翻译：导管装置
公开(公告)号：US07578787B2
公开(公告)日：2009-08-25
申请号：US11040468
申请日：2005-01-21
申请人： Jan Boese , Martin Kleen , Norbert Rahn
发明人： Jan Boese , Martin Kleen , Norbert Rahn
IPC分类号： A61B1/00 , A61M31/00 , A61M25/00
CPC分类号： A61M25/0105 , A61M25/0155 , A61M2025/0161
摘要： Catheter device, comprising a catheter (2) for introduction into a hollow organ, especially a vessel, with a number of bending elements (12, 12a-12f, 12a′-12e′) arranged around the longitudinal axis of the catheter and distributed over at least a part of the catheter length, which can be activated separately for a specified change of shape via a control device (5), as well as a number of bending sensors (15, 15a-15e, 15a′-15e′) arranged around the longitudinal axis of the catheter and distributed over at least a part of the catheter length communicating with a control device (5), with the control device (5) being embodied to determine the given geometrical shape of the catheter (2) on the basis of the bending sensor signals and to determine the change of shape of the bending elements (12, 12a-12f, 12a′-12e′) necessary for a movement of the catheter (2) by a forward movement length preferably specifiable on the user side to enable the catheter (2) to move by itself at least in part, by explicit bend-dependent force application to the wall of the organ (16).
摘要翻译：导管装置，包括用于引入中空器官，特别是血管的导管（2），其具有围绕导管的纵向轴线布置的多个弯曲元件（12,12a-12f，12a'-12e'），并分布在导管长度的至少一部分，其可以通过控制装置（5）以及多个弯曲传感器（15,15a-15e，15a'-15e'）分别被激活以形成规定的形状变化，围绕所述导管的纵向轴线并且分布在与控制装置（5）连通的导管长度的至少一部分上，所述控制装置（5）被实施为确定所述导管（2）的给定几何形状弯曲传感器信号的基础并且确定导管（2）移动所需的弯曲元件（12,12a-12f，12a'-12e'）的形状的变化，该向前移动长度优选地可以在用户上指定侧使得导管（2）至少部分地移动到其自身明显的弯曲依赖力施加到器官的壁（16）。

7. 发明授权

US07460642B2 Method for generating an x-ray image sequence 有权
标题翻译：用于生成x射线图像序列的方法
公开(公告)号：US07460642B2
公开(公告)日：2008-12-02
申请号：US11478464
申请日：2006-06-29
申请人： Jan Boese , Norbert Rahn , Bernhard Sandkamp
发明人： Jan Boese , Norbert Rahn , Bernhard Sandkamp
IPC分类号： H05G1/42
CPC分类号： A61B6/12 , A61B6/06 , A61B6/4441 , A61B6/542 , A61B6/545
摘要： With a method for generating an x-ray image sequence for supporting an intervention on a patient with a catheter or guide wire for instance, automatic recognition of the catheter is carried out with recorded x-ray images using a computer system. The x-ray image recording parameters are changed on the basis of the determined quality of the imaging of the object, with the x-ray device preferably being automatically activated with the changed x-ray image recording parameters, to record x-ray images. The doctor can therefore concentrate on the actual intervention and does not have to worry about operating the x-ray device.
摘要翻译：通过使用例如用导管或引导线产生用于支持对患者的介入的X射线图像序列的方法，使用计算机系统用记录的X射线图像进行导管的自动识别。基于所确定的物体的成像质量来改变X射线图像记录参数，其中X射线装置优选地通过改变的X射线图像记录参数被自动激活，以记录x射线图像。因此，医生可以专注于实际的干预，而不必担心操作x射线装置。

8. 发明授权

US07366563B2 Catheter device 有权
标题翻译：导管装置
公开(公告)号：US07366563B2
公开(公告)日：2008-04-29
申请号：US11012971
申请日：2004-12-14
申请人： Martin Kleen , Marcus Pfister , Norbert Rahn
发明人： Martin Kleen , Marcus Pfister , Norbert Rahn
IPC分类号： A61B5/05
CPC分类号： A61B5/0071 , A61B5/0073 , A61B5/0084 , A61B5/06 , A61B5/062 , A61B5/7285 , A61B34/20 , A61B90/36 , A61B90/361 , A61B2034/2051 , A61B2090/367 , A61B2090/373
摘要： Catheter device for insertion into an area being examined, in particular into a vessel or cavity-containing organ in the body of a person or animal, wherein in the area of the catheter tip a device (3) is provided for emitting excitation light for light-optically exciting an area being examined surrounding the catheter tip, furthermore a device (3) is provided for collecting response light emitted, owing to excitation, from the area being examined, and furthermore a position sensor (13, 24, 27) is provided enabling the catheter tip's spatial position and/or orientation to be registered in a system of coordinates of a position-registering system (7, 14).
摘要翻译：用于插入被检查区域的导管装置，特别是插入人或动物身体中的容器或含腔器官中，其中在导管末端的区域中设置有用于发射光的激发光的装置（3） - 光学激发围绕导管尖端的被检查的区域，此外，提供了一种装置（3），用于从被检查的区域收集由于激发而发射的响应光，并且还提供了位置传感器（13,24,27）使得导管末端的空间位置和/或取向能够登记在位置登记系统（7,14）的坐标系统中。

9. 发明申请

US20080044105A1 Method for Determining a Transformation of Coordinates of Different Images of an Object 有权
标题翻译：确定对象不同图像坐标变换的方法
公开(公告)号：US20080044105A1
公开(公告)日：2008-02-21
申请号：US11631769
申请日：2005-07-05
申请人： Jan Boese , Martin Kleen , Norbert Rahn
发明人： Jan Boese , Martin Kleen , Norbert Rahn
IPC分类号： G06K9/32
CPC分类号： G06T7/33 , G06T7/32 , G06T2207/30004
摘要： Disclosed is a method for registering images of an object according to which a landmark that is common to the images is first identified, and the transformations in relation to the remaining degrees of freedom are determined by means of a position alignment that is not based on the landmark.
摘要翻译：公开了一种用于登记物体的图像的方法，根据该方法，首先识别与图像相同的地标，并且通过不基于该图像的位置对准来确定与剩余自由度相关的变换地标

10. 发明申请

US20070265518A1 Method and arrangement for locating a medical instrument at least partly inserted into an object under examination 审中-公开
标题翻译：用于定位至少部分地插入被检查物体的医疗器械的方法和装置
公开(公告)号：US20070265518A1
公开(公告)日：2007-11-15
申请号：US11522262
申请日：2006-09-15
申请人： Jan Boese , Norbert Rahn , Bernhard Sandkamp
发明人： Jan Boese , Norbert Rahn , Bernhard Sandkamp
IPC分类号： A61B5/05
CPC分类号： A61B90/36 , A61B6/00 , A61B6/541 , A61B8/543 , A61B34/10 , A61B34/20 , A61B90/39 , A61B2090/364 , A61B2090/374 , A61B2090/376
摘要： The invention relates to a method for locating a medical instrument (2a, 2b) at least partly inserted into an object under examination (U), there being acquired (11, 13) images of the object under examination (U) which capture the medical instrument (2a, 2b). A method which requires as little user interaction as possible can be provided by virtue of the fact that an image is acquired under first acquisition conditions and a substantially identical image is acquired under second acquisition conditions (11, 13), and the fact that the medical instrument (2a, 2b) is located from a subtraction (14) of image data sets of first and second acquisition conditions.
摘要翻译：本发明涉及一种用于定位至少部分地插入被检查物体（U）的医疗器械（2a，2b）的方法，存在被检查对象（U）的（11,13）图像，其被捕获医疗器械（2a，2b）。可以通过在第一获取条件下获取图像并且在第二获取条件（11,13）下获取基本相同的图像的事实来提供尽可能少的用户交互尽可能少的方法，以及医疗仪器（2a，2b）位于第一和第二获取条件的图像数据集的减法（14）中。

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