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1. 发明专利

JP2010151677A Uterine cancer diagnosis method and uterine cancer diagnosis kit 审中-公开
标题翻译：子宫癌诊断方法和子宫癌诊断包
公开(公告)号：JP2010151677A
公开(公告)日：2010-07-08
申请号：JP2008331273
申请日：2008-12-25
申请人： National Cancer Center-Japan , Olympus Corp , オリンパス株式会社 , 国立がんセンター総長
发明人： KOBAYASHI TAMIYO , MURASE YUMI , MATSUMURA YASUHIRO , KOGA NOBUKATSU , YASUNAGA MASAHIRO
IPC分类号： G01N33/574 , G01N33/543
摘要： PROBLEM TO BE SOLVED: To provide an uterine cancer diagnosis method, which is a cell base screening method for directly measuring and analyzing cervical cancer and body cancer cells, non-invasive, decreasing test load, and obtaining diagnosis result with high reliability, and a kit used in the diagnosis method.
SOLUTION: According to this uterine cancer diagnosis method, an uterine cancer is diagnosed according to whether an uterine cancer cell is contained in a living body sample. The method includes: (a1) a process of dyeing cells in the living body sample after being fixed in a cell observation container; and (b1) a process of acquiring a microscopic image of the cell dyed in the process (a1), and analyzing the image to detect an uterine cancer cell. The living body sample derives from a womb. A uterine cancer diagnosis kit is also provided which is used in the diagnosis method for the uterine cancer.
COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供一种子宫癌诊断方法，其是用于直接测量和分析子宫颈癌和体癌细胞的非侵入性，降低的测试负荷并获得具有高可靠性的诊断结果的细胞基础筛选方法，以及用于诊断方法的试剂盒。解决方案：根据该子宫癌诊断方法，根据子宫癌细胞是否含有活体样本来诊断子宫癌。该方法包括：（a1）固定在细胞观察容器中后，将活体样品中的细胞染色的工序; 和（b1）获得在步骤（a1）中染色的细胞的显微图像并分析该图像以检测子宫癌细胞的过程。活体样本来源于子宫。还提供了用于子宫癌诊断方法的子宫癌诊断试剂盒。版权所有（C）2010，JPO＆INPIT

2. 发明专利

JP2010151678A Large intestine cancer diagnosis method and kit for large intestine cancer diagnosis 审中-公开
标题翻译：大肠癌诊断方法和大肠癌诊断试剂盒
公开(公告)号：JP2010151678A
公开(公告)日：2010-07-08
申请号：JP2008331274
申请日：2008-12-25
申请人： National Cancer Center-Japan , Olympus Corp , オリンパス株式会社 , 国立がんセンター総長
发明人： KOBAYASHI TAMIYO , MURASE YUMI , MATSUMURA YASUHIRO , KOGA NOBUKATSU , YASUNAGA MASAHIRO
IPC分类号： G01N33/574 , G01N21/78 , G01N33/53 , G01N33/543
摘要： PROBLEM TO BE SOLVED: To provide a large intestine cancer diagnosis method and a kit for the large intestine cancer diagnosis, non-invasive, decreasing test load, and obtaining diagnosis result with high reliability, and a kit for the method.
SOLUTION: This large intestine cancer diagnosis method includes: a process (a-1) of adding a solid phase support to which a collecting antibody specifically coupled to a cell surface antigen appearing in common to a normal cell derived from a large intestine mucous and a large intestine cancer cell is coupled through a linker to a feces sample and mixing the same to form a large intestine cancer cell-collecting antibody-solid phase support complex; a process (a-2) of collecting the formed complex; a process (a-3) of separating the large intestine cancer cell in the collected complex from the solid phase support; a process (a-4) of fixing the obtained large intestine cancer cell in a cell observation container, and dyeing the same using a detecting antibody specifically coupled to the large intestine cancer cell; and a process (b) of acquiring a microscopic image of the dyed large intestine cancer cell and analyzing the image to detect a large intestine cancer cell. The linker is formed of protein G, protein A or DNA.
COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供大肠癌诊断方法和用于大肠癌诊断，非侵入性，降低试验负荷并获得高可靠性的诊断结果的试剂盒，以及该方法的试剂盒。解决方案：这种大肠癌诊断方法包括：添加固相支持物的方法（a-1），其中特异性偶联于来自大肠的正常细胞共同出现的细胞表面抗原的收集抗体粘液和大肠癌细胞通过接头与粪便样品偶联并混合，形成大肠癌细胞收集抗体 - 固相支持复合物; 收集形成的络合物的方法（a-2）将收集的复合物中的大肠癌细胞与固相载体分离的方法（a-3）将获得的大肠癌细胞固定在细胞观察容器中的方法（a-4），并使用与大肠癌细胞特异性结合的检测抗体对其进行染色; 以及获取染色的大肠癌细胞的显微图像并分析图像以检测大肠癌细胞的方法（b）。接头由蛋白G，蛋白A或DNA组成。版权所有（C）2010，JPO＆INPIT

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