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1. 发明申请

US20130244929A1 BRIDGED LIPOGLYCOPEPTIDES THAT POTENTIATE THE ACTIVITY OF BETA-LACTAM ANTIBACTERIALS 审中-公开
标题翻译：阻止β-乳酸菌抗菌活性的桥联脂质体
公开(公告)号：US20130244929A1
公开(公告)日：2013-09-19
申请号：US13583462
申请日：2011-03-04
申请人： Michel Gallant , Karine Villeneuve , Patrick Beaulieu , Joel Robichaud , Helene Juteau , Yves Gareau , Sherman T. Waddell , Nancy Kevin , Xin Gu , Joann Huber , Michael J. Salvatore, JR. , Kenneth Wilson , Scott K. Smith , Deborah Zink
发明人： Michel Gallant , Karine Villeneuve , Patrick Beaulieu , Joel Robichaud , Helene Juteau , Yves Gareau , Sherman T. Waddell , Nancy Kevin , Xin Gu , Joann Huber , Michael J. Salvatore, JR. , Kenneth Wilson , Scott K. Smith , Deborah Zink
IPC分类号： A61K38/08 , A61K31/407 , C07K7/02
CPC分类号： A61K38/08 , A61K31/407 , A61K38/00 , C07K5/0202 , C07K7/02
摘要： The present invention provides novel lipoglycopeptide compounds which are Type 1 signal peptidase inhibitors (SpsB). Compounds of the present invention are useful for the treatment of various bacterial related infectious diseases, particularly when used as a potentiator of a β-lactam antibiotic such as imipenem and ertapenem. Accordingly, the present invention provides a method for the treatment of bacterial related infections using the compounds described herein, either alone or in combination with a β-lactam antibiotic.
摘要翻译：本发明提供了作为1型信号肽酶抑制剂（SpsB）的新型脂多糖化合物。本发明的化合物可用于治疗各种细菌相关感染性疾病，特别是用作β-内酰胺抗生素如亚胺培南和厄他替班的增效剂时。因此，本发明提供了使用本文所述的化合物单独或与β-内酰胺抗生素组合治疗细菌相关感染的方法。

2. 发明申请

US20140316322A1 WRAPPING APPARATUS 审中-公开
标题翻译：包装设备
公开(公告)号：US20140316322A1
公开(公告)日：2014-10-23
申请号：US13868576
申请日：2013-04-23
申请人： Kenneth Wilson
发明人： Kenneth Wilson
IPC分类号： A61F15/00 , A61F15/02
CPC分类号： A61F15/002 , A61F15/02
摘要： A wrapping apparatus for wrapping a sheet of a covering material from a roll onto an outer surface of a surgical site. The wrapping apparatus includes a handle and a body portion having a housing, a first end, and a second end. The housing and the first and second ends generally defining an interior region that is configured to receive the placement of the roll. The wrapping apparatus further includes first and second spindles that are configured to allow rotation of the roll relative to the handle for the dispensing of the sheet of covering material from the roll. The wrapping apparatus may also include a cap that is operably connected to the second end, and which secures the roll to the wrapping apparatus. Additionally, the wrapping apparatus may include a cutting apparatus that cuts or tears dispensed covering material away from the roll of covering material.
摘要翻译：一种用于将覆盖材料片从卷包裹到外科手术部位的外表面上的包装装置。包装装置包括手柄和具有壳体，第一端和第二端的主体部分。壳体以及第一和第二端部大体上限定了内部区域，该内部区域被配置为容纳辊的放置。包装设备还包括第一和第二主轴，其构造成允许辊相对于把手旋转以从辊中分配覆盖材料片。包装设备还可以包括可操作地连接到第二端并且将卷固定到包装设备的盖。此外，包装设备可以包括切割或撕裂分配的覆盖材料远离覆盖材料卷的切割设备。

3. 发明申请

US20050033925A1 Multi-processor computer system with cache-flushing system using memory recall 失效
标题翻译：具有缓存刷新系统的多处理器计算机系统使用存储器调用
公开(公告)号：US20050033925A1
公开(公告)日：2005-02-10
申请号：US10655661
申请日：2003-09-05
申请人： Kenneth Wilson , Fong Pong , Lance Russell , Tung Nguyen , Lu Xu
发明人： Kenneth Wilson , Fong Pong , Lance Russell , Tung Nguyen , Lu Xu
IPC分类号： G06F12/00 , G06F12/08
CPC分类号： G06F12/0808 , G06F12/0804 , G06F12/0817 , G06F2212/2542
摘要： A cache coherent distributed shared memory multi-processor computer system is provided with a memory controller which includes a recall unit. The recall unit allows selective forced write-backs of dirty cache lines to the home memory. After a request is posted in the recall unit, a recall (“flush”) command is issued which forces the owner cache to write-back the dirty cache line to be flushed. The memory controller will inform the recall unit as each recall operation is completed. The recall unit operation will be interrupted when all flush requests are completed.
摘要翻译：高速缓存一致分布式共享存储器多处理器计算机系统具有包括调用单元的存储器控制器。调用单元允许将脏的高速缓存行的选择性强制回写到家庭存储器。在调用单元中发布请求后，会发出召回（“flush”）命令，强制所有者高速缓存写回要清除的脏高速缓存行。每次召回操作完成后，存储器控制器将通知召回单元。所有刷新请求完成后，调用单元操作将中断。

4. 发明授权

US06446427B1 Solid fuel regression rate control method and device 失效
标题翻译：固体燃料回归率控制方法和装置
公开(公告)号：US06446427B1
公开(公告)日：2002-09-10
申请号：US09618412
申请日：2000-07-18
申请人： Kenneth Yu , Klaus C. Schadow , Kenneth Wilson , Timothy Parr
发明人： Kenneth Yu , Klaus C. Schadow , Kenneth Wilson , Timothy Parr
IPC分类号： C06D500
CPC分类号： F02K7/105 , F02K9/26 , F05D2260/96 , F05D2260/962
摘要： The present invention relates to a method and device for controlling the solid fuel regression rate of a solid fuel ramjet engine. In a preferred embodiment of the present invention, pressure oscillations are excited using active, closed-loop control to vary the heat transfer, and in turn the regression rate of a solid fuel ramjet engine. The pressure oscillations are excited by introducing small disturbances into the shear layer. The disturbances are amplified in the shear layer and excite pressure oscillations. The disturbances are introduced at a certain phase relative to the pressure oscillations. This is accomplished by closed-loop control. By varying the phase, the amplitude of the pressure oscillations can also be varied, which in turn will vary the heat transfer, regression rate, and thrust level.
摘要翻译：本发明涉及一种用于控制固体燃料冲压式喷气发动机的固体燃料回收率的方法和装置。在本发明的一个优选实施例中，使用主动闭环控制来激发压力振荡，以改变传热，并且进而改变固体燃料冲压式喷气发动机的回归率。通过在剪切层中引入小的扰动来激发压力振荡。扰动在剪切层中被放大并且激发压力振荡。在相对于压力振荡的某一阶段引入干扰。这是通过闭环控制实现的。通过改变相位，压力振荡的幅度也可以变化，这反过来将改变传热，回归率和推力水平。

5. 发明授权

US5012376A Tape head cleaner cartridge having a mesh cleaning layer 失效
标题翻译：具有网眼清洁层的带头清洁剂盒
公开(公告)号：US5012376A
公开(公告)日：1991-04-30
申请号：US410288
申请日：1989-09-21
申请人： Kyriacos Joannou , Kenneth Wilson , Alan B. Lowry
发明人： Kyriacos Joannou , Kenneth Wilson , Alan B. Lowry
IPC分类号： G11B5/41 , G11B23/04
CPC分类号： G11B5/41 , G11B23/049 , Y10S15/12
摘要： A tape head cleaner cartridge for receipt in a tape machine having a magnetic tape head and comprising a cartridge housing for supporting a cleaning pad that is supported by and operated from a lever. The lever may be manually operated to cause the cleaning pad to transition across the tape head in direction of tape travel. In an alternate embodiment of the invention, the cartridge supports both a magnetic head cleaning pad and a capstan cleaning pad. A dispenser is provided for a plurality of cleaning pads. A kit is provided for containing the cartridge, dispenser and cleaning fluid.
摘要翻译：一种用于接收在具有磁带头的带式机中的带头清洁器盒，并且包括用于支撑由杠杆支撑和操作的清洁垫的盒壳体。杠杆可以被手动操作，以使得清洁垫在磁带行进方向上跨越磁带头。在本发明的替代实施例中，盒支持磁头清洁垫和绞盘清洁垫。为多个清洁垫提供分配器。提供了一个用于容纳墨盒，分配器和清洁液的工具箱。

6. 发明授权

US4626807A Phase shifting device 失效
标题翻译：相移装置
公开(公告)号：US4626807A
公开(公告)日：1986-12-02
申请号：US744040
申请日：1985-06-12
申请人： Kenneth Wilson
发明人： Kenneth Wilson
IPC分类号： H01P1/185 , H01P3/08
CPC分类号： H01P1/185
摘要： A phase shifting device including a coupling device having an input port, an output port and a further port. The further port is connected to a transmission line, along the length of which are connected a number of switches. Each switch is operable to connect a low impedance across the transmission line such that an input signal applied to the input port is reflected at a connected one of the switches to produce an output signal at the output port whose phase is shifted relative to that of the input signal by an amount dependent on the length of transmission line traversed by the input signal. Alternatively the capacitance of each of the switches may be operated so as to vary the propagation constant of the transmission line to thereby produce the required phase shift.
摘要翻译：一种移相装置，包括具有输入端口，输出端口和另一端口的耦合装置。另外的端口连接到传输线，其长度连接有多个开关。每个开关可操作以在传输线路上连接低阻抗，使得施加到输入端口的输入信号在连接的一个开关处被反射以在输出端口处产生输出信号，该输出端口的相位相对于输入信号取决于输入信号所经过的传输线的长度。或者，可以操作每个开关的电容，以便改变传输线的传播常数，从而产生所需的相移。

7. 发明授权

US09068310B2 Sediment retention bag 有权
标题翻译：沉积物保留袋
公开(公告)号：US09068310B2
公开(公告)日：2015-06-30
申请号：US13317683
申请日：2011-10-25
申请人： Kenneth Wilson
发明人： Kenneth Wilson
IPC分类号： E02B3/02 , C02F1/52 , C02F1/28 , C02F1/56 , C02F1/00
CPC分类号： E02B3/023 , C02F1/286 , C02F1/52 , C02F1/5263 , C02F1/56 , C02F2001/007 , Y02A10/28
摘要： A sediment retention device including a water-permeable outer containment structure, a water-impermeable injection tube including an outlet disposed within the outer containment structure, and a flocculent treatment material disposed within the injection tube. The injection tube can include an agitation structure to promote mixing contaminated water with the treatment material. A baffle including water distribution openings can be disposed over the outlet to distribute water into the outer containment structure.
摘要翻译：一种沉积物保持装置，包括透水的外部容纳结构，包括设置在外部容纳结构内的出口的不透水的注入管和设置在注射管内的絮凝处理材料。注入管可以包括搅拌结构，以促进将污染的水与处理材料混合。包括分配开口的挡板可布置在出口上方以将水分配到外部容纳结构中。

8. 发明授权

US08860417B2 Downhole activation system using magnets and method thereof 有权
标题翻译：使用磁体的井下激活系统及其方法
公开(公告)号：US08860417B2
公开(公告)日：2014-10-14
申请号：US13351904
申请日：2012-01-17
申请人： Kenneth Wilson
发明人： Kenneth Wilson
IPC分类号： G01V3/08 , G01V3/00 , E21B31/06
CPC分类号： E21B23/00 , E21B4/00 , E21B34/066 , E21B34/102 , E21B41/00
摘要： A downhole activation system within a tubular. The system includes an axially movable mover. A first magnet attached to the mover. The first magnet axially movable with the mover. A second magnet separated from the first magnet. The second magnet magnetically repulsed by the first magnet. A biasing device urging the second magnet towards the first magnet; wherein movement of the first magnet via the mover towards the second magnet moves the second magnet in a direction against the biasing device. Also included is a method of activating an activatable member in a downhole tubular.
摘要翻译：管内的井下活化系统。该系统包括可轴向移动的移动器。附在动臂上的第一颗磁铁。第一个磁体与动子可以轴向移动。与第一磁体分离的第二磁体。由第一磁铁磁力排斥的第二磁体。朝向第一磁体推动第二磁体的偏置装置; 其中所述第一磁体经由所述动子朝向所述第二磁体的移动使所述第二磁体沿抵靠所述偏置装置的方向移动。还包括激活井下管中的可激活构件的方法。

9. 发明授权

US08674100B2 Inhibitors of C-FMS kinase 有权
标题翻译： C-FMS激酶抑制剂
公开(公告)号：US08674100B2
公开(公告)日：2014-03-18
申请号：US11736635
申请日：2007-04-18
申请人： Carl R. Illig , Shelley K. Ballentine , Jinsheng Chen , Renee Louise DesJariais , Sanath K. Meegalla , Mark Wall , Kenneth Wilson
发明人： Carl R. Illig , Shelley K. Ballentine , Jinsheng Chen , Renee Louise DesJariais , Sanath K. Meegalla , Mark Wall , Kenneth Wilson
IPC分类号： C07D417/12 , C07D279/12 , C07D413/12 , C07D403/12 , C07D233/22 , C07D405/12 , A61K31/535 , A61K31/54 , A61K31/497 , A61K31/445 , A61K31/415
CPC分类号： C07D401/12 , C07C53/18 , C07D233/90 , C07D235/24 , C07D307/68 , C07D401/14 , C07D403/12 , C07D405/12 , C07D491/056
摘要： The invention is directed to compounds of Formula I: wherein Z, X, J, R2 and W are as set forth in the specification, as well as solvates, hydrates, tautomers and pharmaceutically acceptable salts thereof, that inhibit protein tyrosine kinases, especially c-fms kinase. The compounds of formula I are useful for treating a variety of disorders including autoimmune diseases such as rheumatoid arthritis, multiple sclerosis and psoriasis.
摘要翻译：本发明涉及式I化合物：其中Z，X，J，R 2和W如说明书中所述，以及其抑制蛋白酪氨酸激酶的溶剂合物，水合物，互变异构体和药学上可接受的盐，特别是c -fms激酶。式I的化合物可用于治疗各种疾病，包括自身免疫性疾病如类风湿性关节炎，多发性硬化和牛皮癣。

10. 发明申请

US20130305825A1 METHOD OF MONITORING THE POSITION OF A VALVE 审中-公开
标题翻译：监控阀位置的方法
公开(公告)号：US20130305825A1
公开(公告)日：2013-11-21
申请号：US13895984
申请日：2013-05-16
申请人： Joseph Comparetto , Kenneth Wilson
发明人： Joseph Comparetto , Kenneth Wilson
IPC分类号： G01N29/44
CPC分类号： G01N29/4427 , F02D11/106 , F02D41/0077 , F02D2041/286 , F02D2041/288 , F02D2200/0404 , F16K37/0041
摘要： A method of detecting a valve position includes imparting a vibration-inducing energy to a valve, detecting vibration of the valve and producing a sensor signal corresponding to the vibration of the valve, processing the sensor signal determining a measured response of the valve, and comparing the measured response to one or more predetermined characteristic frequencies for selected valve positions to determine the position of the valve.
摘要翻译：检测阀位置的方法包括向阀施加振动诱发能量，检测阀的振动并产生对应于阀的振动的传感器信号，处理传感器信号以确定阀的测量响应，以及比较对所选阀位置的一个或多个预定特征频率的测量响应，以确定阀的位置。

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