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1. 发明申请

US20060038118A1 Microwave-assisted chromatography preparation 有权
标题翻译：微波辅助色谱法制备
公开(公告)号：US20060038118A1
公开(公告)日：2006-02-23
申请号：US10923243
申请日：2004-08-20
申请人： Michael Collins , Wyatt Hargett , James Thomas , Michael Collins , E. Barnhardt
发明人： Michael Collins , Wyatt Hargett , James Thomas , Michael Collins , E. Barnhardt
IPC分类号： H05H3/02
CPC分类号： H05B6/806 , F26B3/347 , F26B5/048 , F26B9/003 , F26B21/14 , G01N1/44 , G01N30/06 , G01N2030/567
摘要： An instrument and associated method are disclosed for preparing samples for column chromatography. The method includes the steps of applying microwave energy to a sample composition containing at least one solvent to encourage a chemical reaction and generate desired products, thereafter mixing an absorbent media with the sample to absorb the solvent, the media being compatible with liquid chromatography that will separate the expected products, being chemically inert to the expected products, and being added in an amount sufficient to provide a substantially dry mixture of the media and the sample, but less than an amount that overly broadens the resolution of the sample during liquid chromatography, thereafter applying microwave energy to the dry mixture of the media and the sample to thereby encourage the solvent to evaporate under the influence of the microwave energy, and thereafter adding the dry mixture of the media and the remaining sample to a liquid chromatography column and separating the components of the remaining sample for identification and purification purposes.
摘要翻译：公开了用于制备用于柱色谱法的样品的仪器和相关方法。该方法包括以下步骤：向含有至少一种溶剂的样品组合物施加微波能量以促进化学反应并产生所需产物，然后将吸收介质与样品混合以吸收溶剂，该介质与液相色谱相容，将期望的产品分离，对预期产品具有化学惰性，并且以足以提供介质和样品的基本上干燥的混合物的量加入，但小于在液相色谱法过度扩大样品分辨率的量，然后将微波能量施加到介质和样品的干燥混合物中，从而促使溶剂在微波能量的影响下蒸发，然后将介质和剩余样品的干混合物加入液相色谱柱中，剩余样品的组分用于鉴定和纯化目的。

2. 发明申请

US20050133498A1 Method and apparatus for continuous flow microwave-assisted chemistry techniques 审中-公开
标题翻译：连续流微波辅助化学技术的方法和装置
公开(公告)号：US20050133498A1
公开(公告)日：2005-06-23
申请号：US11047348
申请日：2005-01-28
申请人： Michael Collins , Michael Collins , Wyatt Hargett , Edward King , Gary Busse
发明人： Michael Collins , Michael Collins , Wyatt Hargett , Edward King , Gary Busse
IPC分类号： B01J19/12 , C07C51/38 , C07C67/03 , C07C67/08 , C07C221/00 , C07C223/06 , H05B6/78 , H05B6/80
CPC分类号： H05B6/806 , B01J19/126 , B01J2219/0009 , B01J2219/00162 , B01J2219/1227 , B01J2219/1239 , C07C51/38 , C07C67/03 , C07C67/08 , C07C221/00 , C07C57/44 , C07C69/76 , C07C69/78 , C07C223/06
摘要： The invention is a method and associated instrument for microwave assisted chemistry. The invention includes the steps of directing a continuous flow of fluid through a microwave cavity while applying microwave radiation to the cavity and to the continuous flow of materials therein, monitoring the pressure of the fluid in the cavity; and cooling the fluid in the cavity when the pressure exceeds a predetermined setpoint pressure.
摘要翻译：本发明是用于微波辅助化学的方法和相关仪器。本发明包括以下步骤：引导流体连续流过微波空腔，同时向空腔施加微波辐射并且在其中连续流动材料，监测空腔中的流体的压力; 并且当压力超过预定的设定点压力时，冷却腔体中的流体。

3. 发明申请

US20060219710A1 Spectroscopy-based real-time control for microwave-assisted chemistry 有权
公开(公告)号：US20060219710A1
公开(公告)日：2006-10-05
申请号：US11097859
申请日：2005-04-01
申请人： Michael McManus , Michael Collins , Michael Collins
发明人： Michael McManus , Michael Collins , Michael Collins
IPC分类号： H05B6/50
CPC分类号： H05B6/806 , B01J19/126 , B01J2219/1215 , B01J2219/1227 , B01J2219/123 , B01J2219/1233 , B01J2219/1236 , B01J2219/1239 , B01J2219/1242 , B01J2219/1245 , B01J2219/1254 , B01J2219/1263 , B01J2219/1266 , B01J2219/1269 , B01J2219/1272 , B01J2219/1284 , B01J2219/1293 , G01N21/65 , G01N21/68
摘要： The invention is an instrument and method for microwave-assisted chemical synthesis. The instrument includes a source of microwave radiation for applying microwave energy to a sample, a microwave cavity in wave communication with the source for holding the sample during the application of microwave energy, and a substantially monochromatic radiation source in electromagnetic communication with the cavity for applying substantially monochromatic light to the sample. The instrument further includes a detector positioned to detect Raman scattering of light from the monochromatic source by the sample, and a controller in signal communication with the microwave energy source and the Raman scattering detector for moderating the application of microwave energy to the sample based upon the detected Raman scattering.

4. 发明申请

US20060261058A1 Microwave-Assisted Chromatography Preparation 有权
标题翻译：微波辅助色谱法制备
公开(公告)号：US20060261058A1
公开(公告)日：2006-11-23
申请号：US11456997
申请日：2006-07-12
申请人： Michael Collins , Wyatt Hargett , James Thomas , Michael Collins , E. Barnhardt
发明人： Michael Collins , Wyatt Hargett , James Thomas , Michael Collins , E. Barnhardt
IPC分类号： B01L9/00
CPC分类号： H05B6/806 , F26B3/347 , F26B5/048 , F26B9/003 , F26B21/14 , G01N1/44 , G01N30/06 , G01N2030/567
摘要： An instrument and associated method are disclosed for preparing samples for column chromatography. The method includes the steps of applying microwave energy to a sample composition containing at least one solvent to encourage a chemical reaction and generate desired products, thereafter mixing an absorbent media with the sample to absorb the solvent, the media being compatible with liquid chromatography that will separate the expected products, being chemically inert to the expected products, and being added in an amount sufficient to provide a substantially dry mixture of the media and the sample, but less than an amount that overly broadens the resolution of the sample during liquid chromatography, thereafter applying microwave energy to the dry mixture of the media and the sample to thereby encourage the solvent to evaporate under the influence of the microwave energy, and thereafter adding the dry mixture of the media and the remaining sample to a liquid chromatography column and separating the components of the remaining sample for identification and purification purposes.
摘要翻译：公开了用于制备用于柱色谱法的样品的仪器和相关方法。该方法包括以下步骤：向含有至少一种溶剂的样品组合物施加微波能量以促进化学反应并产生所需产物，然后将吸收介质与样品混合以吸收溶剂，该介质与液相色谱相容，将期望的产品分离，对预期产品具有化学惰性，并且以足以提供介质和样品的基本上干燥的混合物的量加入，但小于在液相色谱法过度扩大样品分辨率的量，然后将微波能量施加到介质和样品的干燥混合物中，从而促使溶剂在微波能量的影响下蒸发，然后将介质和剩余样品的干混合物加入液相色谱柱中，剩余样品的组分用于鉴定和纯化目的。

5. 发明授权

US10672286B2 Cloud based test environment 审中-公开
公开(公告)号：US10672286B2
公开(公告)日：2020-06-02
申请号：US12899085
申请日：2010-10-06
申请人： Steve Saxon , Michael Collins , Dan Weinmann , William Dorman
发明人： Steve Saxon , Joel Neubeck , Michael Collins , Dan Weinmann , William Dorman
IPC分类号： G09B7/02 , G06F9/50 , G09B7/00 , G09B5/00 , G06Q50/20 , G06Q10/06 , G06F21/31
摘要： Systems and methods described herein provide for administering and proctoring of a secure online examination utilizing a ‘cloud’ computing environment. The cloud computing environment provides scalable, shared computing resources such as processing, memory, communications, storage and other hardware and software resources associated with the online examination. The computing resources provided by the cloud computing environment can be provisioned dynamically to match the requirements of the particular computing tasks carried out at the client and/or server level during the administration of the examination.

6. 发明授权

US08815215B2 Hydrophobic tooth whitening system and methods of use 有权
标题翻译：疏水牙齿美白系统及使用方法
公开(公告)号：US08815215B2
公开(公告)日：2014-08-26
申请号：US10915125
申请日：2004-08-10
申请人： Michael Prencipe , Suman K Chopra , Michael Collins
发明人： Michael Prencipe , Suman K Chopra , Michael Collins
IPC分类号： A61Q11/00 , A61K6/00 , A61K8/25 , A61K8/22 , A61C19/06 , A61K8/81 , A61K8/891
CPC分类号： A61K8/89 , A61C19/066 , A61K8/22 , A61K8/8176 , A61K8/891 , A61K8/895 , A61Q11/00
摘要： A tooth whitening system comprising a dental tray having a surface operable to confront a tooth surface, and a tooth whitening composition comprising a whitening agent and a hydrophobic polymer carrier. The tooth whitening composition is preferably substantially non-water soluble. A tooth whitening kit is also provided using a dental tray and the tooth whitening composition comprising a whitening composition and a hydrophobic polymer carrier.
摘要翻译：一种牙齿美白系统，其包括具有可操作以面对牙齿表面的表面的牙托盘，和包含增白剂和疏水性聚合物载体的牙齿增白组合物。牙齿美白组合物优选基本上是非水溶性的。还使用牙科托盘和含有美白组合物和疏水性聚合物载体的牙齿增白组合物来提供牙齿美白试剂盒。

7. 发明授权

US08814567B2 Dental implant prosthetic device with improved osseointegration and esthetic features 有权
标题翻译：具有改善的骨整合和美观特征的牙种植体假体装置
公开(公告)号：US08814567B2
公开(公告)日：2014-08-26
申请号：US11847476
申请日：2007-08-30
申请人： Kai Zhang , Michael Wallick , Jeffrey A. Bassett , Michael Collins
发明人： Kai Zhang , Michael Wallick , Jeffrey A. Bassett , Michael Collins
IPC分类号： A61C8/00
CPC分类号： A61C8/0012 , A61C8/0006
摘要： Dental implants made at least in part of a porous tantalum material for enhancing the osseointegration of the dental implant into surrounding bone. For example, there is provided a dental implant which includes a porous tantalum portion and an outer portion having a color generally replicating the color of natural teeth. The dental implant further comprises a core portion and the porous tantalum portion at least partially surrounds the core portion. An esthetic portion is disposed at least the outer portion and the porous tantalum portion is disposed for at least partially reinforcing the esthetic portion. After implantation of the implant, bone tissue may osseointegrate into the porous tantalum portion to anchor the implant in position within the surrounding bone. Other embodiments of implants are provided, each implant including at least a portion thereof formed of porous tantalum for improved osseointegration.
摘要翻译：至少部分由多孔钽材料制成的牙种植体，用于增强牙科植入物到骨骼的骨整合。例如，提供了一种牙科植入物，其包括多孔钽部分和具有通常复制天然颜色的颜色的外部部分。牙科植入物还包括芯部分，并且多孔钽部分至少部分地围绕芯部分。至少设置有外观部分的美观部分，多孔钽部分设置成至少部分地加强美观部分。在植入植入物之后，骨组织可以骨整合到多孔钽部分中以将植入物锚定在周围骨骼内的适当位置。提供植入物的其它实施方案，每个植入物包括由多孔钽形成的至少一部分，用于改善骨整合。

8. 发明授权

US08562346B2 Dental implant for a jaw with reduced bone volume and improved osseointegration features 有权
标题翻译：具有减少骨量和改善骨整合特征的颌骨牙植入物
公开(公告)号：US08562346B2
公开(公告)日：2013-10-22
申请号：US12167049
申请日：2008-07-02
申请人： Michael Collins , Jeffrey A. Bassett , Sean Cahill
发明人： Michael Collins , Jeffrey A. Bassett , Sean Cahill
IPC分类号： A61C8/00
CPC分类号： A61C8/0012 , A61C8/0013 , A61C8/0022 , A61C8/0075 , A61C2008/0046 , A61K6/04
摘要： A dental implant has a body with a porous metal portion for engaging bone. The porous metal portion has an outer coronal to apical height and an outer diameter. Both the height and diameter are about 4 mm to about 6 mm. This permits the implant to be placed on a jaw with a reduced bone volume.
摘要翻译：牙科植入物具有用于接合骨的多孔金属部分的主体。多孔金属部分具有顶端高度和外径的外冠。高度和直径都约为4毫米至6毫米。这允许将植入物放置在具有减小的骨量的钳口上。

9. 发明申请

US20120288453A1 FLUORIDE FREE AND ANIONIC SURFACTANT FREE DENTIFRICE HAVING A HIGH MICRO EFFICACY 审中-公开
标题翻译：无氟和无光泽的表面活性剂具有高效率的免费印花
公开(公告)号：US20120288453A1
公开(公告)日：2012-11-15
申请号：US13574100
申请日：2011-01-28
申请人： Michael Collins , Linh Fruge , Barbara Hepler , Kimdra Smith-Webster
发明人： Michael Collins , Linh Fruge , Barbara Hepler , Kimdra Smith-Webster
IPC分类号： A61K8/34 , A61Q11/00
CPC分类号： A61K8/345 , A61K8/36 , A61K2800/30 , A61K2800/5922 , A61Q11/00
摘要： An oral care composition and method are described in which the composition is free of an anionic surfactant and a fluoride source.
摘要翻译：描述了其中组合物不含阴离子表面活性剂和氟化物源的口腔护理组合物和方法。

10. 发明申请

US20100143034A1 Method and Apparatus for a Roadway Marker 审中-公开
标题翻译：道路标记的方法和装置
公开(公告)号：US20100143034A1
公开(公告)日：2010-06-10
申请号：US12626113
申请日：2009-11-25
申请人： Arra David Yeghiayan , Michael Collins
发明人： Arra David Yeghiayan , Michael Collins
IPC分类号： E01F9/00
CPC分类号： E01F9/627 , E01F9/619 , E01F9/692
摘要： A marker includes a base. The base has a first end, a middle portion and a second end, wherein the middle portion is located between the first end and the second end. A spring element is attached to the middle portion of the base. An elongated rod is attached to the spring element at a first end.
摘要翻译：标记包括基座。基部具有第一端部，中部部分和第二端部，其中中间部分位于第一端部和第二端部之间。弹簧元件连接到基座的中间部分。细长的杆在第一端附接到弹簧元件。

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